| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S D Mundle, S Reza, A Ali, Y Mativi, V Shetty, P Venugopal, S A Gregory, A Raz. Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromes. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403560. |
the present studies thus identify the downstream effectors of tnf alpha-inducible apoptosis in mds and so also the suppressors of tnf alpha apoptotic signaling. |
1999-08-19 |
2023-08-12 |
Not clear |
| R Shao, M C Hu, B P Zhou, S Y Lin, P J Chiao, R H von Lindern, B Spohn, M C Hun. E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. The Journal of biological chemistry. vol 274. issue 31. 1999-08-19. PMID:10419449. |
the adenovirus e1a protein has been implicated in increasing cellular susceptibility to apoptosis induced by tumor necrosis factor (tnf); however, its mechanism of action is still unknown. |
1999-08-19 |
2023-08-12 |
Not clear |
| R Shao, M C Hu, B P Zhou, S Y Lin, P J Chiao, R H von Lindern, B Spohn, M C Hun. E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. The Journal of biological chemistry. vol 274. issue 31. 1999-08-19. PMID:10419449. |
since activation of nuclear factor kappab (nf-kappab) has been shown to play an anti-apoptotic role in tnf-induced apoptosis, we examined apoptotic susceptibility and nf-kappab activation induced by tnf in the e1a transfectants and their parental cells. |
1999-08-19 |
2023-08-12 |
Not clear |
| D De Valck, D Y Jin, K Heyninck, M Van de Craen, R Contreras, W Fiers, K T Jeang, R Beyaer. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene. vol 18. issue 29. 1999-08-19. PMID:10435631. |
like a20, overexpression of txbp151 could inhibit apoptosis induced by tumour necrosis factor (tnf) in nih3t3 cells. |
1999-08-19 |
2023-08-12 |
human |
| D De Valck, D Y Jin, K Heyninck, M Van de Craen, R Contreras, W Fiers, K T Jeang, R Beyaer. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases. Oncogene. vol 18. issue 29. 1999-08-19. PMID:10435631. |
furthermore, apoptosis induced by tnf or cd95 (fas/apo-1) was associated with proteolysis of txbp151. |
1999-08-19 |
2023-08-12 |
human |
| A Ashkenazi, R C Pai, S Fong, S Leung, D A Lawrence, S A Marsters, C Blackie, L Chang, A E McMurtrey, A Hebert, L DeForge, I L Koumenis, D Lewis, L Harris, J Bussiere, H Koeppen, Z Shahrokh, R H Schwal. Safety and antitumor activity of recombinant soluble Apo2 ligand. The Journal of clinical investigation. vol 104. issue 2. 1999-08-12. PMID:10411544. |
tnf and fas ligand induce apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their application to cancer therapy. |
1999-08-12 |
2023-08-12 |
mouse |
| D M Katschinski, H I Robins, M Schad, S Frede, J Fandre. Role of tumor necrosis factor alpha in hyperthermia-induced apoptosis of human leukemia cells. Cancer research. vol 59. issue 14. 1999-08-12. PMID:10416602. |
the threshold temperature for the onset of apoptosis was 42 degrees c. whereas hyperthermia exerted no effect on the expression of bcl-2 and bax, heat induced a >30-fold increase of tumor necrosis factor (tnf) alpha mrna expression and a significant increase in tnf-alpha protein secretion. |
1999-08-12 |
2023-08-12 |
human |
| O Cohen, B Inbal, J L Kissil, T Raveh, H Berissi, T Spivak-Kroizaman, E Feinstein, A Kimch. DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. The Journal of cell biology. vol 146. issue 1. 1999-08-09. PMID:10402466. |
here, we report that this kinase is involved in tumor necrosis factor (tnf)-alpha and fas-induced apoptosis. |
1999-08-09 |
2023-08-12 |
Not clear |
| E V Korobko, L P Saschenko, E B Prockhorchouk, I V Korobko, N V Gnuchev, S L Kisele. Resistance to tumor necrosis factor induced apoptosis in vitro correlates with high metastatic capacity of cells in vivo. Immunology letters. vol 67. issue 2. 1999-08-06. PMID:10232385. |
our data demonstrate that those cell lines lacking capability to form metastatic tumors in vivo are susceptible to tnf induced apoptosis in vitro. |
1999-08-06 |
2023-08-12 |
Not clear |
| T Grzela, M Ołdak, J Jóźwiak, J Malejczy. [Induction of apoptosis by receptors for factors from the TNF family]. Postepy higieny i medycyny doswiadczalnej. vol 53. issue 2. 1999-08-03. PMID:10355300. |
[induction of apoptosis by receptors for factors from the tnf family]. |
1999-08-03 |
2023-08-12 |
Not clear |
| T Grzela, M Ołdak, J Jóźwiak, J Malejczy. [Induction of apoptosis by receptors for factors from the TNF family]. Postepy higieny i medycyny doswiadczalnej. vol 53. issue 2. 1999-08-03. PMID:10355300. |
mechanisms leading to induction of apoptosis by tnf family receptors involve intracellular activation of cysteinyl-aspartate-specific proteases (caspases). |
1999-08-03 |
2023-08-12 |
Not clear |
| T Grzela, M Ołdak, J Jóźwiak, J Malejczy. [Induction of apoptosis by receptors for factors from the TNF family]. Postepy higieny i medycyny doswiadczalnej. vol 53. issue 2. 1999-08-03. PMID:10355300. |
the outcome of induction of apoptosis by tnf receptor family depends on the cell type, its physiological condition and influence of environmental factors. |
1999-08-03 |
2023-08-12 |
Not clear |
| K K Donnahoo, B D Shames, A H Harken, D R Meldru. Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury. The Journal of urology. vol 162. issue 1. 1999-07-19. PMID:10379787. |
tnf receptor binding can also induce renal cell apoptosis, the major form of cell death associated with renal ischemia-reperfusion injury. |
1999-07-19 |
2023-08-12 |
Not clear |
| M A Williams, A C Newland, S M Kelse. The potential for monocyte-mediated immunotherapy during infection and malignancy. Part I: apoptosis induction and cytotoxic mechanisms. Leukemia & lymphoma. vol 34. issue 1-2. 1999-07-15. PMID:10350328. |
tnf is highly cytotoxic to micro-organisms and susceptible malignant cells and in most cases delivers its cytotoxic signal to tumour cells by highly regulated mechanisms of programmed cell death or apoptosis. |
1999-07-15 |
2023-08-12 |
Not clear |
| M A Williams, A C Newland, S M Kelse. The potential for monocyte-mediated immunotherapy during infection and malignancy. Part I: apoptosis induction and cytotoxic mechanisms. Leukemia & lymphoma. vol 34. issue 1-2. 1999-07-15. PMID:10350328. |
in this review, the mechanisms by which secreted and monocyte cell-membrane-associated tnf induce apoptosis will be discussed. |
1999-07-15 |
2023-08-12 |
Not clear |
| E Haas, M Grell, H Wajant, P Scheuric. Continuous autotropic signaling by membrane-expressed tumor necrosis factor. The Journal of biological chemistry. vol 274. issue 25. 1999-07-15. PMID:10364265. |
moreover, cycloheximide-induced apoptosis in transmembrane tnf transfectants can be blocked by the caspase inhibitor zvad-fmk and does not necessarily need cell to cell contact, indicating a critical role of constitutive autotropic signaling of tnf.tnf receptor complexes. |
1999-07-15 |
2023-08-12 |
Not clear |
| J B Prins, E C Ledgerwood, P Ameloot, P Vandenabeele, P R Faraco, N A Bright, S O'Rahilly, J R Bradle. Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II. Bioscience reports. vol 18. issue 6. 1999-07-09. PMID:10357175. |
tumor necrosis factor (tnf) may cause apoptosis or necrosis and induces mitochondrial changes that have been proposed to be central to cytotoxicity. |
1999-07-09 |
2023-08-12 |
Not clear |
| J B Prins, E C Ledgerwood, P Ameloot, P Vandenabeele, P R Faraco, N A Bright, S O'Rahilly, J R Bradle. Tumor necrosis factor-induced cytotoxicity is not related to rates of mitochondrial morphological abnormalities or autophagy-changes that can be mediated by TNFR-I or TNFR-II. Bioscience reports. vol 18. issue 6. 1999-07-09. PMID:10357175. |
these changes do not invariably lead to cell death, and survival or progression to apoptosis or necrosis following tnf exposure may depend in part on the extent of mitochondrial damage and/or the autophagic capacity of the cell. |
1999-07-09 |
2023-08-12 |
Not clear |
| P Schneider, R Schwenzer, E Haas, F Mühlenbeck, G Schubert, P Scheurich, J Tschopp, H Wajan. TWEAK can induce cell death via endogenous TNF and TNF receptor 1. European journal of immunology. vol 29. issue 6. 1999-07-08. PMID:10382740. |
here we show that soluble tweak is sufficient to induce apoptosis in kym-1 cells within 18 h. tweak-induced apoptosis is indirect and is mediated by the interaction of endogenous tnf and tnf receptor (tnfr)1, as each tnfr1-fc, neutralizing tnf-specific antibodies and tnfr1-specific fab fragments efficiently antagonize cell death induction. |
1999-07-08 |
2023-08-12 |
Not clear |
| J Li, C A Bombeck, S Yang, Y M Kim, T R Billia. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. The Journal of biological chemistry. vol 274. issue 24. 1999-07-06. PMID:10358093. |
we found that both exogenous no as well as endogenously produced no via adenoviral inducible no synthase gene transfer protected hepatocytes from tumor necrosid factor (tnf) alpha plus actinomycin d (tnfalpha/actd)-induced apoptosis. |
1999-07-06 |
2023-08-12 |
Not clear |