| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Saito, I Kuss, G Dworacki, W Gooding, J T Johnson, T L Whitesid. Spontaneous ex vivo apoptosis of peripheral blood mononuclear cells in patients with head and neck cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 5. issue 6. 1999-09-30. PMID:10389908. |
pbmcs were incubated at 37 degrees c in medium (spontaneous apoptosis) and in the presence of ch-11 antibody (anti-fas) or tumor necrosis factor (tnf)-alpha, both capable of inducing dna fragmentation in activated t cells expressing the tnf family of receptors. |
1999-09-30 |
2023-08-12 |
Not clear |
| Y Liu, V Tergaonkar, S Krishna, E J Androph. Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species. The Journal of biological chemistry. vol 274. issue 35. 1999-09-30. PMID:10455154. |
here we report that, although l929 cells underwent dna fragmentation after exposure to tnf, they retained the morphology of intact nuclei while gaining permeability to propidium iodide, features characteristic of necrosis rather than apoptosis. |
1999-09-30 |
2023-08-12 |
human |
| J R Ciacci-Zanella, C Jone. Fumonisin B1, a mycotoxin contaminant of cereal grains, and inducer of apoptosis via the tumour necrosis factor pathway and caspase activation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 37. issue 7. 1999-09-30. PMID:10496371. |
iap blocks apoptosis which is induced by the tumour necrosis factor (tnf) pathway. |
1999-09-30 |
2023-08-12 |
mouse |
| J R Ciacci-Zanella, C Jone. Fumonisin B1, a mycotoxin contaminant of cereal grains, and inducer of apoptosis via the tumour necrosis factor pathway and caspase activation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 37. issue 7. 1999-09-30. PMID:10496371. |
in summary, these results demonstrate that the tnf pathway and caspases plays an important role in fb1-induced apoptosis. |
1999-09-30 |
2023-08-12 |
mouse |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
caspase-activation and induction of inducible nitric oxide-synthase during tnf alpha-triggered apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
recently, we have shown no.-generation to be essential for tnf alpha-induced apoptosis of various tumor cell lines. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
incubation with tnf alpha (+/- cycloheximide) led to activation of the caspase cascade and was followed by apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
simultaneously, tnf alpha stimulated induction of inos and generation of no.. caspase inhibitors devd-cho, yvad-cmk and yvad-cho effectively inhibited caspase activation and prevented apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
taken together, tnf alpha induces apoptosis in mcf-7 cells by initiating a two-sided effector pathway including inos-induction and activation of caspase 1- and 3-like proteases. |
1999-09-20 |
2023-08-12 |
Not clear |
| J Shibata, H Goto, T Arisawa, Y Niwa, T Hayakawa, A Nakayama, N Mor. Regulation of tumour necrosis factor (TNF) induced apoptosis by soluble TNF receptors in Helicobacter pylori infection. Gut. vol 45. issue 1. 1999-09-17. PMID:10369700. |
regulation of tumour necrosis factor (tnf) induced apoptosis by soluble tnf receptors in helicobacter pylori infection. |
1999-09-17 |
2023-08-12 |
Not clear |
| J Shibata, H Goto, T Arisawa, Y Niwa, T Hayakawa, A Nakayama, N Mor. Regulation of tumour necrosis factor (TNF) induced apoptosis by soluble TNF receptors in Helicobacter pylori infection. Gut. vol 45. issue 1. 1999-09-17. PMID:10369700. |
tnf induces apoptosis in a variety of cells. |
1999-09-17 |
2023-08-12 |
Not clear |
| H Dai, J Guzman, U Costabe. Increased expression of apoptosis signalling receptors by alveolar macrophages in sarcoidosis. The European respiratory journal. vol 13. issue 6. 1999-09-17. PMID:10445626. |
the fas receptor (fasr) and the tumour necrosis factor (tnf) receptor 55/60 kda (tnfr1) are recognized as apoptosis signalling receptors. |
1999-09-17 |
2023-08-12 |
human |
| S Bulfone-Paus, E Bulanova, T Pohl, V Budagian, H Durkop, R Ruckert, U Kunzendorf, R Paus, H Kraus. Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 12. 1999-09-17. PMID:10463949. |
one prominent path toward apoptosis is the ligand-induced association of tnf receptor 1 (tnfr1) with death domain adaptor proteins. |
1999-09-17 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
induction of apoptosis by tumor necrosis factor (tnf) is modulated by changes in the expression and activity of several cell cycle regulatory proteins. |
1999-09-09 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
both compounds blocked cell growth, but only tnf induced the common events of apoptosis, i.e., chromatin condensation and ladder pattern of dna fragmentation in these cell lines. |
1999-09-09 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
the role of proteases in the tnf and butyrolactone-induced apoptosis was evaluated by comparing the number and expression of polypeptides in the cell lysates by gel electrophoresis. |
1999-09-09 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
these findings link the decrease of cyclin-dependent kinase activities to the increase of protease activities within the growth arrest and apoptosis pathways induced by tnf. |
1999-09-09 |
2023-08-12 |
Not clear |
| M Lotz, S Hashimoto, K Küh. Mechanisms of chondrocyte apoptosis. Osteoarthritis and cartilage. vol 7. issue 4. 1999-09-09. PMID:10419776. |
chondrocyte apoptosis can be induced in vitro by nitric oxide donors, but not by pro-inflammatory cytokines, such as il-1 or tnf. |
1999-09-09 |
2023-08-12 |
human |
| P R Faraco, E C Ledgerwood, P Vandenabeele, J B Prins, J R Bradle. Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage. Biochemical and biophysical research communications. vol 261. issue 2. 1999-09-08. PMID:10425195. |
tnf induces caspase activity in both settings, and the broad spectrum caspase inhibitor zvad-fmk inhibits this activity and blocks both tnf-induced apoptosis and necrosis. |
1999-09-08 |
2023-08-12 |
Not clear |
| W S Wold, K Doronin, K Toth, M Kuppuswamy, D L Lichtenstein, A E Tollefso. Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic. Current opinion in immunology. vol 11. issue 4. 1999-09-02. PMID:10448144. |
adenoviruses encode proteins that block responses to interferons, intrinsic cellular apoptosis, killing by cd8(+) cytotoxic t lymphocytes and killing by the death ligands tnf, fas ligand and trail. |
1999-09-02 |
2023-08-12 |
Not clear |