| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
recently, we have shown no.-generation to be essential for tnf alpha-induced apoptosis of various tumor cell lines. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
incubation with tnf alpha (+/- cycloheximide) led to activation of the caspase cascade and was followed by apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
simultaneously, tnf alpha stimulated induction of inos and generation of no.. caspase inhibitors devd-cho, yvad-cmk and yvad-cho effectively inhibited caspase activation and prevented apoptosis. |
1999-09-20 |
2023-08-12 |
Not clear |
| C Binder, M Schulz, W Hiddemann, M Oelleric. Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis. Anticancer research. vol 19. issue 3A. 1999-09-20. PMID:10470105. |
taken together, tnf alpha induces apoptosis in mcf-7 cells by initiating a two-sided effector pathway including inos-induction and activation of caspase 1- and 3-like proteases. |
1999-09-20 |
2023-08-12 |
Not clear |
| J Shibata, H Goto, T Arisawa, Y Niwa, T Hayakawa, A Nakayama, N Mor. Regulation of tumour necrosis factor (TNF) induced apoptosis by soluble TNF receptors in Helicobacter pylori infection. Gut. vol 45. issue 1. 1999-09-17. PMID:10369700. |
regulation of tumour necrosis factor (tnf) induced apoptosis by soluble tnf receptors in helicobacter pylori infection. |
1999-09-17 |
2023-08-12 |
Not clear |
| J Shibata, H Goto, T Arisawa, Y Niwa, T Hayakawa, A Nakayama, N Mor. Regulation of tumour necrosis factor (TNF) induced apoptosis by soluble TNF receptors in Helicobacter pylori infection. Gut. vol 45. issue 1. 1999-09-17. PMID:10369700. |
tnf induces apoptosis in a variety of cells. |
1999-09-17 |
2023-08-12 |
Not clear |
| H Dai, J Guzman, U Costabe. Increased expression of apoptosis signalling receptors by alveolar macrophages in sarcoidosis. The European respiratory journal. vol 13. issue 6. 1999-09-17. PMID:10445626. |
the fas receptor (fasr) and the tumour necrosis factor (tnf) receptor 55/60 kda (tnfr1) are recognized as apoptosis signalling receptors. |
1999-09-17 |
2023-08-12 |
human |
| S Bulfone-Paus, E Bulanova, T Pohl, V Budagian, H Durkop, R Ruckert, U Kunzendorf, R Paus, H Kraus. Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 13. issue 12. 1999-09-17. PMID:10463949. |
one prominent path toward apoptosis is the ligand-induced association of tnf receptor 1 (tnfr1) with death domain adaptor proteins. |
1999-09-17 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
induction of apoptosis by tumor necrosis factor (tnf) is modulated by changes in the expression and activity of several cell cycle regulatory proteins. |
1999-09-09 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
both compounds blocked cell growth, but only tnf induced the common events of apoptosis, i.e., chromatin condensation and ladder pattern of dna fragmentation in these cell lines. |
1999-09-09 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
the role of proteases in the tnf and butyrolactone-induced apoptosis was evaluated by comparing the number and expression of polypeptides in the cell lysates by gel electrophoresis. |
1999-09-09 |
2023-08-12 |
Not clear |
| J E Belizário, S Sherwood, W Beça. Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 32. issue 4. 1999-09-09. PMID:10347813. |
these findings link the decrease of cyclin-dependent kinase activities to the increase of protease activities within the growth arrest and apoptosis pathways induced by tnf. |
1999-09-09 |
2023-08-12 |
Not clear |
| M Lotz, S Hashimoto, K Küh. Mechanisms of chondrocyte apoptosis. Osteoarthritis and cartilage. vol 7. issue 4. 1999-09-09. PMID:10419776. |
chondrocyte apoptosis can be induced in vitro by nitric oxide donors, but not by pro-inflammatory cytokines, such as il-1 or tnf. |
1999-09-09 |
2023-08-12 |
human |
| P R Faraco, E C Ledgerwood, P Vandenabeele, J B Prins, J R Bradle. Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage. Biochemical and biophysical research communications. vol 261. issue 2. 1999-09-08. PMID:10425195. |
tnf induces caspase activity in both settings, and the broad spectrum caspase inhibitor zvad-fmk inhibits this activity and blocks both tnf-induced apoptosis and necrosis. |
1999-09-08 |
2023-08-12 |
Not clear |
| W S Wold, K Doronin, K Toth, M Kuppuswamy, D L Lichtenstein, A E Tollefso. Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic. Current opinion in immunology. vol 11. issue 4. 1999-09-02. PMID:10448144. |
adenoviruses encode proteins that block responses to interferons, intrinsic cellular apoptosis, killing by cd8(+) cytotoxic t lymphocytes and killing by the death ligands tnf, fas ligand and trail. |
1999-09-02 |
2023-08-12 |
Not clear |
| A Laouar, D Glesne, E Huberma. Involvement of protein kinase C-beta and ceramide in tumor necrosis factor-alpha-induced but not Fas-induced apoptosis of human myeloid leukemia cells. The Journal of biological chemistry. vol 274. issue 33. 1999-09-01. PMID:10438532. |
the role of protein kinase c-beta (pkc-beta) in apoptosis induced by tumor necrosis factor (tnf)-alpha and anti-fas monoclonal antibody (mab) in the human myeloid hl-60 leukemia cell line was studied by using its variant hl-525, which is deficient in pkc-beta. |
1999-09-01 |
2023-08-12 |
human |
| D R Meldrum, K K Donnaho. Role of TNF in mediating renal insufficiency following cardiac surgery: evidence of a postbypass cardiorenal syndrome. The Journal of surgical research. vol 85. issue 2. 1999-08-30. PMID:10423318. |
following its production and release, tnf results in both renal and myocardial apoptosis and dysfunction. |
1999-08-30 |
2023-08-12 |
Not clear |
| D R Meldrum, K K Donnaho. Role of TNF in mediating renal insufficiency following cardiac surgery: evidence of a postbypass cardiorenal syndrome. The Journal of surgical research. vol 85. issue 2. 1999-08-30. PMID:10423318. |
the purposes of this review are: (1) to evaluate the evidence which indicates that tnf is produced by the heart following cardiopulmonary bypass; (2) to examine the effect of tnf on myocardial performance; (3) to outline the mechanisms by which the kidney produces significant tnf in response to ischemia and reperfusion; (5) to investigate the role of tnf in renal ischemia-reperfusion injury, (6) to describe the mechanisms of tnf-induced renal cell apoptosis, and (7) to suggest potential anti-tnf strategies designed to reduce renal insufficiency following cardiac surgery. |
1999-08-30 |
2023-08-12 |
Not clear |
| S D Mundle, S Reza, A Ali, Y Mativi, V Shetty, P Venugopal, S A Gregory, A Raz. Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromes. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403560. |
furthermore, high amounts of tumor necrosis factor alpha (tnf alpha) have previously been correlated with apoptosis in mds marrows. |
1999-08-19 |
2023-08-12 |
Not clear |
| S D Mundle, S Reza, A Ali, Y Mativi, V Shetty, P Venugopal, S A Gregory, A Raz. Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromes. Cancer letters. vol 140. issue 1-2. 1999-08-19. PMID:10403560. |
finally in hl60 cells the effects of different caspase inhibitors and pentoxifylline (ptx) (interferes with lipid signaling of cytokines) on tnf alpha-induced apoptosis were evaluated. |
1999-08-19 |
2023-08-12 |
Not clear |