| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
establishment of a mutant from human monocytic leukaemia u937 that exhibits a genetically dominant resistance to tnf alpha-induced apoptosis. |
2003-12-23 |
2023-08-12 |
human |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
tumour necrosis factor-alpha (tnf alpha) is a cytokine that induces apoptosis in various cell systems by binding to a tnf receptor (tnfr). |
2003-12-23 |
2023-08-12 |
human |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
to study tnf alpha-induced apoptosis, we isolated and characterized a novel tnf alpha resistant variant, u937/tnf clone ii-5, from human monocytic leukaemia u937 cells. |
2003-12-23 |
2023-08-12 |
human |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
the ii-5 cells resist apoptosis by tnf alpha and anti-fas antibody but not by anticancer drugs, such as vp-16 and ara-c. somatic cell hybridization between u937 and ii-5 showed that the apoptosis resistance to tnf alpha in ii-5 was genetically dominant. |
2003-12-23 |
2023-08-12 |
human |
| R G Goodwin, C A Smit. The TRAIL of Death. Apoptosis : an international journal on programmed cell death. vol 3. issue 2. 2003-12-23. PMID:14646505. |
the tnf ligand family member termed trail has been shown to induce apoptosis in a wide variety of transformed cell lines. |
2003-12-23 |
2023-08-12 |
Not clear |
| U Brinkmann, E Mansfield, I Pasta. Effects of BCL-2 overexpression on the sensitivity of MCF-7 breast cancer cells to ricin, diphtheria and Pseudomonas toxin and immunotoxins. Apoptosis : an international journal on programmed cell death. vol 2. issue 2. 2003-12-23. PMID:14646554. |
we compared the sensitivity of mcf-7 breast cancer cells that were stably transfected with a bcl-2 expression plasmid and thus protected against apoptosis and of mcf-7 cells transfected with a control plasmid towards ricin, diphtheria and pseudomonas toxin, a pseudomonas toxin-derived immunotoxin (lmb-7) and tumour necrosis factor alpha (tnf). |
2003-12-23 |
2023-08-12 |
Not clear |
| Quan Chen, Subrata Ray, Mohamad A Hussein, Gordan Srkalovic, Alexandru Almasa. Role of Apo2L/TRAIL and Bcl-2-family proteins in apoptosis of multiple myeloma. Leukemia & lymphoma. vol 44. issue 7. 2003-12-18. PMID:12916874. |
apo2 ligand or tumour necrosis factor (tnf)-related apoptosis-inducing ligand (apo2l/trail) is a member of the tnf gene superfamily that selectively induces apoptosis in tumor cells of diverse origins through engagement of death receptors. |
2003-12-18 |
2023-08-12 |
Not clear |
| A Wanchu, A Bhatnagar, B Kumar, P Bambery, S Sing. Reduced apoptosis by pentoxiphylline among patients with HIV infection. International immunopharmacology. vol 3. issue 3. 2003-12-17. PMID:12639813. |
caspase 8 (flice) is involved in apoptosis mediated by fas and p55 tumor necrosis factor (tnf) receptor ligation. |
2003-12-17 |
2023-08-12 |
Not clear |
| Bärbel Lange-Sperandio, Simone Fulda, Alain Vandewalle, Robert L Chevalie. Macrophages induce apoptosis in proximal tubule cells. Pediatric nephrology (Berlin, Germany). vol 18. issue 4. 2003-12-17. PMID:12700958. |
although tumor necrosis factor (tnf)-alpha and transforming growth factor (tgf)-beta(1), measured by elisa, increased significantly in supernatants from activated macrophages, blocking tnf-alpha and tgf-beta did not decrease apoptosis in pksv-pr cells co-cultured with macrophages. |
2003-12-17 |
2023-08-12 |
Not clear |
| H N LeBlanc, A Ashkenaz. Apo2L/TRAIL and its death and decoy receptors. Cell death and differentiation. vol 10. issue 1. 2003-12-12. PMID:12655296. |
apo2 ligand or tumour necrosis factor-related apoptosis-inducing ligand (apo2l/trail) is one of the several members of the tumour necrosis factor (tnf) gene superfamily that induce apoptosis through engagement of death receptors (drs). |
2003-12-12 |
2023-08-12 |
Not clear |
| Shulin Wang, Wafik S El-Deir. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene. vol 22. issue 53. 2003-12-11. PMID:14634624. |
tumor necrosis factor-related apoptosis-inducing ligand or apo 2 ligand (trail/apo2l) is a member of the tumor necrosis factor (tnf) family of ligands capable of initiating apoptosis through engagement of its death receptors. |
2003-12-11 |
2023-08-12 |
Not clear |
| Shulin Wang, Wafik S El-Deir. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene. vol 22. issue 53. 2003-12-11. PMID:14634624. |
death receptors, members of the tnf receptor family, signal apoptosis independently of the p53 tumor-suppressor gene. |
2003-12-11 |
2023-08-12 |
Not clear |
| Xavier Mariett. [Pathophysiology of Sjögren's syndrome]. Annales de medecine interne. vol 154. issue 3. 2003-12-09. PMID:12910042. |
recently discovered new elements probably play a role in the pathogenesis of this multifactorial disease: genetic predisposition remains largely unknown, but there isa link between certain hla molecules and the type of autoantibodies secreted; sometimes called autoimmune epithelitis, ss is associated with abnormal apoptosis activity in epithelial cells leading to an abnormal accumulation of degradation products of the cytoskeleton proteins such as alpha- and beta-fordrine and also to the presentation of numerous antinuclear autoantigens to the immune system; significant polyclonal activation of b lymphocytes is probably mediated, at least in part, by a major increase in molecules of the tnf family (e.g. |
2003-12-09 |
2023-08-12 |
Not clear |
| Oskar W Rokhlin, Michael B Cohe. Bisindolylmaleimide IX Induces Reversible and Time-Dependent Tumor Necrosis Factor Receptor Family-Mediated Caspase Activation and Cell Death. Cancer biology & therapy. vol 2. issue 3. 2003-12-04. PMID:12878863. |
using human prostatic carcinoma cell lines du145 and lncap that are resistant to treatment with tnf family death-inducing ligands, we have shown that different, albeit still unidentified, inhibitory factors are responsible for the resistance to trail-, fas-, and tnf-a-mediated apoptosis. |
2003-12-04 |
2023-08-12 |
human |
| Avrum Spira, J David Carroll, Gang Liu, Zeeshan Aziz, Vishal Shah, Hardy Kornfeld, Joseph Kean. Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor. American journal of respiratory cell and molecular biology. vol 29. issue 5. 2003-12-02. PMID:12748057. |
tumor necrosis factor (tnf)-alpha-dependent apoptosis of alveolar macrophages (am) after infection with avirulent mycobacterium tuberculosis (mtb) results in bacillary death and the destruction of a growth niche for the pathogen. |
2003-12-02 |
2023-08-12 |
human |
| Tatsuya Saitoh, Masafumi Nakayama, Hiroyasu Nakano, Hideo Yagita, Naoki Yamamoto, Shoji Yamaok. TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. The Journal of biological chemistry. vol 278. issue 38. 2003-11-20. PMID:12840022. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a member of the tnf superfamily that has been shown to induce angiogenesis, apoptosis in tumor cells, and nf-kappab activation through binding to its receptor, fibroblast growth factor-inducible 14. |
2003-11-20 |
2023-08-12 |
Not clear |
| Upasna Gaur, Bharat B Aggarwa. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochemical pharmacology. vol 66. issue 8. 2003-11-20. PMID:14555214. |
regulation of proliferation, survival and apoptosis by members of the tnf superfamily. |
2003-11-20 |
2023-08-12 |
human |
| Upasna Gaur, Bharat B Aggarwa. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochemical pharmacology. vol 66. issue 8. 2003-11-20. PMID:14555214. |
various members of the tnf super family mediate either proliferation, survival, or apoptosis of cells. |
2003-11-20 |
2023-08-12 |
human |
| Eric D Tang, Cun-Yu Wang, Yue Xiong, Kun-Liang Gua. A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. The Journal of biological chemistry. vol 278. issue 39. 2003-11-17. PMID:12867425. |
in addition, the ubiquitination of nemo is mediated by c-iap1, an inhibitor of apoptosis protein that is a component of the tnf receptor signaling complex. |
2003-11-17 |
2023-08-12 |
Not clear |
| Zofia Sułowska, Ewa Majewska, Henryk Tchórzewski, Magdalena Klin. Effect of exogenous opioid peptides on TNF-alpha-induced human neutrophil apoptosis in vitro. Archivum immunologiae et therapiae experimentalis. vol 51. issue 4. 2003-11-12. PMID:12956436. |
the effect of opioid peptides such as met-enkephalin (m-enk) and beta-endorphin (beta-end) on tumor necrosis factor (tnf)-alpha-induced apoptosis in human neutrophils in vitro was investigated. |
2003-11-12 |
2023-08-12 |
human |