| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stuart J McKinno. Glaucoma: ocular Alzheimer's disease? Frontiers in bioscience : a journal and virtual library. vol 8. 2003-10-24. PMID:12957857. |
caspase-8, which initiates apoptosis after activation of receptors of the tumor necrosis factor (tnf) superfamily, is also activated in rgcs. |
2003-10-24 |
2023-08-12 |
rat |
| Eunice N Hatada, Richard K G Do, Amos Orlofsky, Hsiou-Chi Liou, Michael Prystowsky, Ian C M MacLennan, Jorge Caamano, Selina Chen-Kian. NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 2. 2003-10-23. PMID:12847243. |
b lymphocyte stimulator (blys), a tnf family protein essential for peripheral b cell development, functions primarily through attenuation of b cell apoptosis. |
2003-10-23 |
2023-08-12 |
Not clear |
| Gudrun Totzke, Klaus Schulze-Osthoff, Reiner U Jänick. Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition. Oncogene. vol 22. issue 39. 2003-10-21. PMID:12970750. |
tnf did also not induce pge(2) production in mcf-7/casp-3 cells stably expressing cox-2; however, nimesulide strongly enhanced tnf-induced apoptosis in these cells. |
2003-10-21 |
2023-08-12 |
Not clear |
| Yoshihiko Yano, Yoshitake Hayashi, Miyuki Nakaji, Hidenobu Nagano, Yasushi Seo, Toshiaki Ninomiya, Seitetsu Yoon, Atushi Wada, Midori Hirai, Soo Ryang Kim, Hiroshi Yokozaki, Masato Kasug. Different apoptotic regulation of TRAIL-caspase pathway in HBV- and HCV-related hepatocellular carcinoma. International journal of molecular medicine. vol 11. issue 4. 2003-10-16. PMID:12632104. |
like the fas/fas-l system, the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) transduces apoptosis in a number of cancers; it is also a clinical candidate for cancer therapy. |
2003-10-16 |
2023-08-12 |
human |
| Marshall S Baker, Xiaojuan Chen, Alizah R Rotramel, Jeffrey J Nelson, Dixon B Kaufma. Interferon regulatory factor-1 down-regulates cytokine-induced IP-10 expression in pancreatic islets. Surgery. vol 134. issue 2. 2003-10-16. PMID:12947309. |
interferon (ifn)-gamma acts synergistically with interleukin (il)-1beta and tumor necrosis factor (tnf)-alpha to activate isoform of nitric oxide synthetase (inos) gene expression, induce apoptosis, and impair glucose-stimulated insulin release (gsir) in pancreatic islets. |
2003-10-16 |
2023-08-12 |
Not clear |
| Frederic Clermont, Emmanuelle Adam, Jacques E Dumont, Bernard Robay. Survival pathways regulating the apoptosis induced by tumour necrosis factor-alpha in primary cultured bovine endothelial cells. Cellular signalling. vol 15. issue 5. 2003-10-14. PMID:12639717. |
the aim of the present study was to identify biochemical pathways driving the resistance of endothelial cells to apoptosis induced by tumour necrosis factor-alpha (tnf). |
2003-10-14 |
2023-08-12 |
cattle |
| Peter W Szlosarek, Frances R Balkwil. Tumour necrosis factor alpha: a potential target for the therapy of solid tumours. The Lancet. Oncology. vol 4. issue 9. 2003-10-09. PMID:12965278. |
it is a vital member of the multifunctional tnf superfamily and has important roles in immunity and cellular remodelling as well as influencing apoptosis and cell survival. |
2003-10-09 |
2023-08-12 |
Not clear |
| C S Mitsiades, V Poulaki, N Mitsiade. The role of apoptosis-inducing receptors of the tumor necrosis factor family in thyroid cancer. The Journal of endocrinology. vol 178. issue 2. 2003-10-07. PMID:12904168. |
the tumor necrosis factor (tnf) family comprises several ligands, such as the prototype tnf-alpha, the fas ligand (fasl) and tnf-related apoptosis-inducing ligand (trail/apo2l), which trigger apoptosis in susceptible cells by activating respective cell-surface receptors. |
2003-10-07 |
2023-08-12 |
human |
| Salah-Eddine Lamhamedi-Cherradi, Shijun Zheng, Roland M Tisch, Youhai H Che. Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes. Diabetes. vol 52. issue 9. 2003-10-07. PMID:12941766. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) selectively induces apoptosis of tumor cells but not most normal cells. |
2003-10-07 |
2023-08-12 |
mouse |
| Yulian Wu, Bing Han, Hongyu Luo, Raphael Roduit, Theodora W Salcedo, Paul A Moore, Jun Zhang, Jiangping W. DcR3/TR6 effectively prevents islet primary nonfunction after transplantation. Diabetes. vol 52. issue 9. 2003-10-07. PMID:12941767. |
dcr3/tr6 is a soluble death decoy receptor belonging to the tumor necrosis factor (tnf) receptor family, and it can block apoptosis mediated by several tnf receptor family members such as fas and lt beta r. in this study, we used tr6 to protect islets from pnf after transplantation. |
2003-10-07 |
2023-08-12 |
mouse |
| Leanne Cartee, Sonia C Maggio, Rebecca Smith, Heidi M Sankala, Paul Dent, Steven Gran. Protein kinase C-dependent activation of the tumor necrosis factor receptor-mediated extrinsic cell death pathway underlies enhanced apoptosis in human myeloid leukemia cells exposed to bryostatin 1 and flavopiridol. Molecular cancer therapeutics. vol 2. issue 1. 2003-10-03. PMID:12533676. |
bryostatin 1/fp-induced apoptosis was significantly diminished in cells ectopically expressing dominant-negative fas-associated death domain or by coadministration of tumor necrosis factor (tnf)-alpha soluble receptors, implicating the extrinsic pathway in bryostatin 1/fp actions. |
2003-10-03 |
2023-08-12 |
human |
| S Dubey, S Nityanan. Involvement of Fas and TNF pathways in the induction of apoptosis of T cells by antithymocyte globulin. Annals of hematology. vol 82. issue 8. 2003-09-30. PMID:12783210. |
involvement of fas and tnf pathways in the induction of apoptosis of t cells by antithymocyte globulin. |
2003-09-30 |
2023-08-12 |
Not clear |
| S Dubey, S Nityanan. Involvement of Fas and TNF pathways in the induction of apoptosis of T cells by antithymocyte globulin. Annals of hematology. vol 82. issue 8. 2003-09-30. PMID:12783210. |
our next objective was to investigate the effect of atg on modulation of fas and tnf pathways, the two main pathways of t-cell apoptosis. |
2003-09-30 |
2023-08-12 |
Not clear |
| S Dubey, S Nityanan. Involvement of Fas and TNF pathways in the induction of apoptosis of T cells by antithymocyte globulin. Annals of hematology. vol 82. issue 8. 2003-09-30. PMID:12783210. |
we conclude that atg-induced apoptosis in t cells involves both fas and tnf pathways and tnf-alpha is produced much earlier than fas and fasl expression. |
2003-09-30 |
2023-08-12 |
Not clear |
| Kohsuke Takeda, Atsushi Matsuzawa, Hideki Nishitoh, Hidenori Ichij. Roles of MAPKKK ASK1 in stress-induced cell death. Cell structure and function. vol 28. issue 1. 2003-09-26. PMID:12655147. |
recent findings from analyses of ask1-deficient mice have revealed that ask1 is required for apoptosis induced by oxidative stress, tnf and endoplasmic reticulum (er) stress. |
2003-09-26 |
2023-08-12 |
mouse |
| Olivier Micheau, Jürg Tschop. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell. vol 114. issue 2. 2003-09-22. PMID:12887920. |
induction of tnf receptor i-mediated apoptosis via two sequential signaling complexes. |
2003-09-22 |
2023-08-12 |
Not clear |
| Qing-Sheng Mi, Dalam Ly, S-E Lamhamedi-Cherradi, Konstantin V Salojin, Li Zhou, Marsha Grattan, Craig Meagher, Peter Zucker, Youhai H Chen, James Nagle, Dennis Taub, Terry L Delovitc. Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 diabetes in NOD mice. Diabetes. vol 52. issue 8. 2003-09-15. PMID:12882912. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is expressed in different tissues and cells, including pancreas and lymphocytes, and can induce apoptosis in various tumor cells but not in most normal cells. |
2003-09-15 |
2023-08-12 |
mouse |
| Jennifer L Aron, Mark R Parthun, Guido Marcucci, Shinichi Kitada, Andrew P Mone, Melanie E Davis, Tiansheng Shen, Timothy Murphy, Joseph Wickham, Chris Kanakry, David M Lucas, John C Reed, Michael R Grever, John C Byr. Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein. Blood. vol 102. issue 2. 2003-09-12. PMID:12649137. |
depsipeptide-induced apoptosis is caspase dependent, selectively involving the tumor necrosis factor (tnf) receptor (extrinsic pathway) initiating caspase 8 and effector caspase 3. |
2003-09-12 |
2023-08-12 |
Not clear |
| Shinobu Suzuki, Nobutaka Suzuki, Christine Mirtsos, Thomas Horacek, Elizabeth Lye, Seo-Kyu Noh, Alexandra Ho, Denis Bouchard, Tak W Mak, Wen-Chen Ye. Nur77 as a survival factor in tumor necrosis factor signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 14. 2003-09-04. PMID:12815108. |
we report here that nur77 can play a role in antagonizing apoptosis in tnf signaling. |
2003-09-04 |
2023-08-12 |
mouse |
| Shinobu Suzuki, Nobutaka Suzuki, Christine Mirtsos, Thomas Horacek, Elizabeth Lye, Seo-Kyu Noh, Alexandra Ho, Denis Bouchard, Tak W Mak, Wen-Chen Ye. Nur77 as a survival factor in tumor necrosis factor signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 14. 2003-09-04. PMID:12815108. |
interestingly, unlike most antiapoptotic molecules, this induced expression of nur77 is largely independent of nf-kappa b. ectopic expression of nur77 can protect wild-type, traf2-/-, and rela-/- cells from apoptosis induced by tnf, whereas expression of a dominant-negative form of nur77 (dn-nur77) accelerates tnf-mediated cell death in the mutant cells. |
2003-09-04 |
2023-08-12 |
mouse |