| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shinobu Suzuki, Nobutaka Suzuki, Christine Mirtsos, Thomas Horacek, Elizabeth Lye, Seo-Kyu Noh, Alexandra Ho, Denis Bouchard, Tak W Mak, Wen-Chen Ye. Nur77 as a survival factor in tumor necrosis factor signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 14. 2003-09-04. PMID:12815108. |
in mouse embryonic fibroblasts, nur77 remains in the nucleus in response to tnf and is not translocated to the mitochondria, where it was reported to mediate apoptosis. |
2003-09-04 |
2023-08-12 |
mouse |
| Min Wu, Liang-Guo Xu, Zhonghe Zhai, Hong-Bing Sh. SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription. The Journal of biological chemistry. vol 278. issue 29. 2003-08-27. PMID:12736262. |
consistent with its role in inhibition of nf-kappab-dependent transcription, sink also sensitized cells to apoptosis induced by tnf and trail (tnf-related apoptosis-inducing ligand). |
2003-08-27 |
2023-08-12 |
Not clear |
| A Markotic, L Hensley, T Geisbert, K Spik, C Schmaljoh. Hantaviruses induce cytopathic effects and apoptosis in continuous human embryonic kidney cells. The Journal of general virology. vol 84. issue Pt 8. 2003-08-27. PMID:12867652. |
although studies by others suggest that the nucleocapsid protein of puumala virus interacts with the fas-mediated apoptosis enhancer daxx at the gene expression level, it was determined that members of the tnf receptor superfamily did not contribute to the apoptosis observed in infected hek293 cells. |
2003-08-27 |
2023-08-12 |
human |
| Yong Song, Yi Shi, Alden H Harken, Xianzhong Men. Induction of type II alveolar epithelial cells apoptosis in mouse by lipopolysaccharide does not require TNF-alpha. Chinese medical journal. vol 116. issue 4. 2003-08-21. PMID:12875736. |
to examine whether lipopolysaccharide (lps)-induced apoptosis correlates with tnf-alpha release by type ii alveolar epithelial cells (aec ii), whether tnf-alpha knockout (tnf ko) abrogates the induction of apoptosis by lps and whether tnf-alpha is sufficient to induce apoptosis in this cell type. |
2003-08-21 |
2023-08-12 |
mouse |
| Michelle Emily Weisfelner, Alice B Gottlie. The role of apoptosis in human epidermal keratinocytes. Journal of drugs in dermatology : JDD. vol 2. issue 4. 2003-08-19. PMID:12884460. |
both the passive and active apoptosis, including the tnf alpha and fas-mediated pathways are highlighted, with regards to utilization in normal human epidermal turnover. |
2003-08-19 |
2023-08-12 |
human |
| R Onuki, H Kawasaki, T Baba, K Tair. Use of Bid-ribozymes to characterize and Bid-affiliated apoptotic pathway. Nucleic acids research. Supplement (2001). issue 1. 2003-08-15. PMID:12836265. |
the data assign caspase 9 as an upstream activator of caspase 7 in tnf alpha-induced bid-mediated apoptosis. |
2003-08-15 |
2023-08-12 |
Not clear |
| Nicholas Harper, Michelle Hughes, Marion MacFarlane, Gerald M Cohe. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. The Journal of biological chemistry. vol 278. issue 28. 2003-08-14. PMID:12721308. |
tnf failed to induce apoptosis in fadd- and caspase-8-deficient jurkat cells, indicating that these apoptotic mediators were required for tnf-induced apoptosis. |
2003-08-14 |
2023-08-12 |
Not clear |
| Nicholas Harper, Michelle Hughes, Marion MacFarlane, Gerald M Cohe. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. The Journal of biological chemistry. vol 278. issue 28. 2003-08-14. PMID:12721308. |
taken together these results suggest that apoptosis signaling by tnf is distinct from that induced by cd95 and trail. |
2003-08-14 |
2023-08-12 |
Not clear |
| Nazario Rubio, Begoña Martin-Clemente, Howard L Lipto. High-neurovirulence GDVII virus induces apoptosis in murine astrocytes through tumor necrosis factor (TNF)-receptor and TNF-related apoptosis-inducing ligand. Virology. vol 311. issue 2. 2003-08-13. PMID:12842625. |
high-neurovirulence gdvii virus induces apoptosis in murine astrocytes through tumor necrosis factor (tnf)-receptor and tnf-related apoptosis-inducing ligand. |
2003-08-13 |
2023-08-12 |
mouse |
| P Valente, D Arzani, A Cesario, S Margaritora, E Carbone, P Russ. TNF increases camptothecin-induced apoptosis by inhibition of NF-kappaB. European journal of cancer (Oxford, England : 1990). vol 39. issue 10. 2003-08-12. PMID:12826051. |
tnf increases camptothecin-induced apoptosis by inhibition of nf-kappab. |
2003-08-12 |
2023-08-12 |
human |
| P Valente, D Arzani, A Cesario, S Margaritora, E Carbone, P Russ. TNF increases camptothecin-induced apoptosis by inhibition of NF-kappaB. European journal of cancer (Oxford, England : 1990). vol 39. issue 10. 2003-08-12. PMID:12826051. |
these findings show that tnf, in combination with cpt, reduces the time that nf-kappab complexes persist in cells likely resulting in the induction of apoptosis. |
2003-08-12 |
2023-08-12 |
human |
| John C Reed, Kutbuddin Doctor, Ana Rojas, Juan M Zapata, Christian Stehlik, Loredana Fiorentino, Jason Damiano, Wilfried Roth, Shu-Ichi Matsuzawa, Ruchi Newman, Shinichi Takayama, Hiroyuki Marusawa, Famming Xu, Guy Salvesen, Adam Godzi. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome research. vol 13. issue 6B. 2003-08-11. PMID:12819136. |
using a combination of public (ncbi) and private (riken) databases, we compared the repertoire of apoptosis and nfkappab-inducing genes in humans and mice from cdna/est/genomic data, focusing on the following domain families: (1) caspase proteases; (2) caspase recruitment domains (card); (3) death domains (dd); (4) death effector domains (ded); (5) bir domains of inhibitor of apoptosis proteins (iaps); (6) bcl-2 homology (bh) domains of bcl-2 family proteins; (7) tumor necrosis factor (tnf)-family ligands; (8) tnf receptors (tnfr); (9) tir domains; (10) paad (pyrin; pyd, dapin); (11) nucleotide-binding nacht domains; (12) trafs; (13) hsp70-binding bag domains; (14) endonuclease-associated cide domains; and (15) miscellaneous additional proteins. |
2003-08-11 |
2023-08-12 |
mouse |
| Kourous A Rezai, Lili Farrokh-Siar, Elzbieta M Gasyna, J Terry Ernest, Gijs A van Sevente. The effect of type I and II interferons on human fetal retinal pigment epithelium-induced apoptosis in Jurkat T cells. Investigative ophthalmology & visual science. vol 44. issue 7. 2003-08-04. PMID:12824262. |
to examine the regulatory effects of interferon (ifn)-alpha, ifn-gamma, transforming growth factor (tgf)-beta, and tumor necrosis factor (tnf)-alpha on human fetal retinal pigment epithelial (hfrpe) cell-induced apoptosis of human jurkat t (jkt) cells. |
2003-08-04 |
2023-08-12 |
human |
| Yashin Sreenivasan, Abira Sarkar, Sunil K Mann. Mechanism of cytosine arabinoside-mediated apoptosis: role of Rel A (p65) dephosphorylation. Oncogene. vol 22. issue 28. 2003-08-01. PMID:12853972. |
arac, but not tnf or ceramide was able to induce apoptosis in these cells as detected by assays for lipid peroxidation, reactive oxygen intermediates generation, caspase activation, cytotoxicity, bcl-2 degradation, and dna fragmentation. |
2003-08-01 |
2023-08-12 |
Not clear |
| Jing Wang, Yang-Xin F. LIGHT (a cellular ligand for herpes virus entry mediator and lymphotoxin receptor)-mediated thymocyte deletion is dependent on the interaction between TCR and MHC/self-peptide. Journal of immunology (Baltimore, Md. : 1950). vol 170. issue 8. 2003-07-31. PMID:12682226. |
we previously reported that light (a cellular ligand for herpes virus entry mediator and lymphotoxin receptor), a tnf family member, plays an important role in thymocyte development via promoting apoptosis of double-positive thymocytes. |
2003-07-31 |
2023-08-12 |
mouse |
| Eui-Cheol Shin, Young Rim Seong, Chul Hoon Kim, Hoguen Kim, Young Soo Ahn, Kunhong Kim, Se Jong Kim, Seung-Suh Hong, Jeon Han Par. Human hepatocellular carcinoma cells resist to TRAIL-induced apoptosis, and the resistance is abolished by cisplatin. Experimental & molecular medicine. vol 34. issue 2. 2003-07-30. PMID:12085986. |
tnf-related apoptosis-inducing ligand (trail), a member of the tnf family, selectively induce apoptosis in various transformed cell lines but not in almost-normal tissues. |
2003-07-30 |
2023-08-12 |
human |
| C A Wilson, J L Brownin. Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis. Cell death and differentiation. vol 9. issue 12. 2003-07-30. PMID:12478469. |
death of ht29 adenocarcinoma cells induced by tnf family receptor activation is caspase-independent and displays features of both apoptosis and necrosis. |
2003-07-30 |
2023-08-12 |
Not clear |
| C A Wilson, J L Brownin. Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis. Cell death and differentiation. vol 9. issue 12. 2003-07-30. PMID:12478469. |
to provide a frame of reference, the phenotype of ht29 death was compared to four other tnf family receptor triggered death events; fas induced jurkat cell apoptosis, tnf/zvad induced l929 fibroblast necrosis, tnf induced death of wehi 164 fibroblastoid cells and tnf/zvad induced u937 death. |
2003-07-30 |
2023-08-12 |
Not clear |
| A Pituch-Noworolska, B Hajto, W Balwierz, K Klu. Induction of apoptosis and bcl-2 expression in acute lymphoblastic leukaemia and non-Hodgkin's lymphoma in children. Haematologia. vol 31. issue 3. 2003-07-25. PMID:11855781. |
this study assessed the induction of apoptosis of acute lymphoblastic leukaemia (all) and non-hodgkin's lymphoma (nhl) blastic cells following in vitro treatment with dexamethasone (dxm), vincristine (vcr), and tumour necrosis factor (tnf) in relation to the expression of bcl-2 and p-gp. |
2003-07-25 |
2023-08-12 |
Not clear |
| S Christakos, F Barletta, M Huening, P Dhawan, Y Liu, A Porta, X Pen. Vitamin D target proteins: function and regulation. Journal of cellular biochemistry. vol 88. issue 2. 2003-07-25. PMID:12520521. |
recent findings have indicated that calbindin-d(28k), the first known target of vitamin d action, is present in osteoblasts and protects against tnf and glucocorticoid induced apoptosis of osteoblastic cells. |
2003-07-25 |
2023-08-12 |
Not clear |