| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vladimir N Ivanov, Anindita Bhoumik, Ze'ev Rona. Death receptors and melanoma resistance to apoptosis. Oncogene. vol 22. issue 20. 2003-07-07. PMID:12789291. |
changes at genomic, transcriptional and post-translational levels of g-proteins and protein kinases (ras, b-raf) and their transcription factor effectors (c-jun, atf2, stat3 and nf-kappab) affects tnf, fas and trail receptors, which play important roles in acquiring melanoma's resistance to apoptosis. |
2003-07-07 |
2023-08-12 |
Not clear |
| Sharron A N Brown, Christine M Richards, Heather N Hanscom, Sheau-Line Y Feng, Jeffrey A Winkle. The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. The Biochemical journal. vol 371. issue Pt 2. 2003-07-03. PMID:12529173. |
the human fn14 protein was recently identified as a cell-surface receptor for the tumour necrosis factor (tnf) superfamily member named tweak (tnf-like weak inducer of apoptosis). |
2003-07-03 |
2023-08-12 |
human |
| Cristina Muñoz-Pinedo, Carmen Ruiz-Ruiz, Carmen Ruiz de Almodóvar, Carmen Palacios, Abelardo López-Riva. Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing. The Journal of biological chemistry. vol 278. issue 15. 2003-07-03. PMID:12556444. |
we show that both substitution of glucose for pyruvate and treatment with 2-deoxyglucose enhanced apoptosis induced by tumor necrosis factor (tnf)-alpha, cd95 agonistic antibody, and tnf-related apoptosis-inducing ligand (trail). |
2003-07-03 |
2023-08-12 |
human |
| Veronica Galvan, Anna Logvinova, Sabina Sperandio, Hidenori Ichijo, Dale E Bredese. Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1). The Journal of biological chemistry. vol 278. issue 15. 2003-07-03. PMID:12556535. |
apoptosis signal-regulating kinase 1 (ask1) is a map kinase kinase kinase (mapkkk) that is required for c-jun n-terminal kinase (jnk) and p38 activation in response to fas and tumor necrosis factor (tnf) receptor stimulation, and for oxidative stress- and tnfalpha-induced apoptosis. |
2003-07-03 |
2023-08-12 |
Not clear |
| Hilmar Quentmeier, Julia Reinhardt, Margarete Zaborski, Hans G Drexle. Granulocyte-macrophage colony-stimulating factor: inhibitor of tumor necrosis factor-induced apoptosis. Leukemia research. vol 27. issue 6. 2003-07-01. PMID:12648514. |
tumor necrosis factor (tnf) can induce proliferation as well as apoptosis in acute myeloid leukemia (aml)-derived cells. |
2003-07-01 |
2023-08-12 |
Not clear |
| Masakazu Sawanobori, Shuichi Yamaguchi, Maki Hasegawa, Miori Inoue, Kenshi Suzuki, Ryuichi Kamiyama, Katsuiku Hirokawa, Masanobu Kitagaw. Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. Leukemia research. vol 27. issue 7. 2003-07-01. PMID:12681357. |
in this study, we examined the role of tumor necrosis factor (tnf)-induced apoptosis in the bone marrow cells of mds patients. |
2003-07-01 |
2023-08-12 |
human |
| Anna Jurewicz, Mariola Matysiak, Krzysztof Tybor, Krzysztof Selma. TNF-induced death of adult human oligodendrocytes is mediated by c-jun NH2-terminal kinase-3. Brain : a journal of neurology. vol 126. issue Pt 6. 2003-07-01. PMID:12764057. |
expression of a dominant-negative mutant of jnk upstream kinase, mkk4/sek1, inhibited apoptosis induced by tnf, whereas expression of a constitutive active mutant of mekk1, an upstream kinase to jnk, accelerates tnf-induced apoptosis. |
2003-07-01 |
2023-08-12 |
human |
| Alma Zernecke, Wolfgang Erl, Line Fraemohs, Michael Lietz, Christian Webe. Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 9. 2003-06-25. PMID:12692090. |
pretreatment of endothelial cells with dpgj2 or pga1 at low concentrations dose dependently inhibited the up-regulation of cam expression and monocyte arrest by tumor necrosis factor (tnf)-alpha but not expression of inhibitor of apoptosis proteins. |
2003-06-25 |
2023-08-12 |
Not clear |
| Daniel F Legler, Olivier Micheau, Marie-Agnès Doucey, Jürg Tschopp, Claude Bro. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity. vol 18. issue 5. 2003-06-25. PMID:12753742. |
engagement of tnf receptor 1 by tnfalpha activates the transcription factor nf-kappab but can also induce apoptosis. |
2003-06-25 |
2023-08-12 |
Not clear |
| Sarah M Richardson-Burns, Douglas J Kominsky, Kenneth L Tyle. Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors. Journal of neurovirology. vol 8. issue 5. 2003-06-23. PMID:12402163. |
reovirus-induced apoptosis in neuronal cultures is initiated by activation of the tumor necrosis factor (tnf) receptor superfamily death receptors and is inhibited by treatment with soluble death receptors (drs). |
2003-06-23 |
2023-08-12 |
mouse |
| Shujie Wang, Zhiliang Wang, Paul Dent, Steven Gran. Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells. Blood. vol 101. issue 9. 2003-06-20. PMID:12522001. |
coadministration of tumor necrosis factor (tnf) soluble receptors, or ectopic expression of crma or dominant-negative caspase-8, abrogated potentiation of paclitaxel-induced mitochondrial injury and apoptosis by bryostatin 1, implicating the extrinsic apoptotic pathway in this process. |
2003-06-20 |
2023-08-12 |
human |
| Katsuhiko Matsumaru, Cheng Ji, Neil Kaplowit. Mechanisms for sensitization to TNF-induced apoptosis by acute glutathione depletion in murine hepatocytes. Hepatology (Baltimore, Md.). vol 37. issue 6. 2003-06-18. PMID:12774022. |
we previously reported that depletion of glutathione in murine hepatocytes by diethylmaleate (dem) or acetaminophen (apap) leads to oxidative stress-dependent necrosis and sensitizes to tumor necrosis factor (tnf)-induced apoptosis in an oxidative stress-independent fashion, which could not be explained by interference with nuclear factor kappab (nf-kappab) nuclear translocation. |
2003-06-18 |
2023-08-12 |
Not clear |
| Kohji Komatsu, Noboru Manabe, Minako Kiso, Munetake Shimabe, Hajime Miyamot. Changes in localization of immune cells and cytokines in corpora lutea during luteolysis in murine ovaries. Journal of experimental zoology. Part A, Comparative experimental biology. vol 296. issue 2. 2003-06-17. PMID:12658721. |
we histochemically investigated the changes in distribution and cell density of macrophages and t lymphocytes and in tumor necrosis factor (tnf)-alpha and interferon (ifn)-gamma, which can induce apoptosis in the luteal cells in murine cls during luteal regression. |
2003-06-17 |
2023-08-12 |
Not clear |
| M Itoh, T Noutomi, H Toyota, J Mizuguch. Etoposide-mediated sensitization of squamous cell carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced loss in mitochondrial membrane potential. Oral oncology. vol 39. issue 3. 2003-06-16. PMID:12618199. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), which belongs to the tnf family of proteins, induces apoptosis in tumor, but not in normal, cells. |
2003-06-16 |
2023-08-12 |
Not clear |
| Takashi Hiromatsu, Toshiki Yajima, Tetsuya Matsuguchi, Hitoshi Nishimura, Worawidh Wajjwalku, Toshiyuki Arai, Yuji Nimura, Yasunobu Yoshika. Overexpression of interleukin-15 protects against Escherichia coli-induced shock accompanied by inhibition of tumor necrosis factor-alpha-induced apoptosis. The Journal of infectious diseases. vol 187. issue 9. 2003-06-04. PMID:12717626. |
interleukin (il)-15, a potent inhibitor of tumor necrosis factor (tnf)-alpha-mediated apoptosis, causes multiple organ failure during endotoxic shock. |
2003-06-04 |
2023-08-12 |
mouse |
| Farideh Sabri, Francesca Chiodi, Jean-Pascal Piret, Cheng-Hong Wei, Eugene Major, Bengt Westermark, Maria G Masucci, Victor Levitsk. Soluble factors released by virus specific activated cytotoxic T-lymphocytes induce apoptotic death of astroglioma cell lines. Brain pathology (Zurich, Switzerland). vol 13. issue 2. 2003-06-04. PMID:12744470. |
experiments with purified lymphokines and lymphokine specific blocking antibodies indicate that synergistic activities of tumor necrosis factor (tnf)-alpha and interferon (inf)-gamma are required for the apoptosis inducing effect on some astroglioma cell lines. |
2003-06-04 |
2023-08-12 |
human |
| Nam-On Ku, Roy M Soetikno, M Bishr Omar. Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury. Hepatology (Baltimore, Md.). vol 37. issue 5. 2003-05-30. PMID:12717381. |
k18 is a major caspase substrate during apoptosis, and k8- or k18-null mice are significantly predisposed to fas- and possibly tumor necrosis factor (tnf)-mediated apoptosis in the liver. |
2003-05-30 |
2023-08-12 |
mouse |
| Nam-On Ku, Roy M Soetikno, M Bishr Omar. Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury. Hepatology (Baltimore, Md.). vol 37. issue 5. 2003-05-30. PMID:12717381. |
this supports the association of keratin mutations with cirrhosis in patients with liver disease and suggests that keratins modulate apoptosis induced by fas but not tnf. |
2003-05-30 |
2023-08-12 |
mouse |
| Myriam Roussigne, Corinne Cayrol, Thomas Clouaire, François Amalric, Jean-Philippe Girar. THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies. Oncogene. vol 22. issue 16. 2003-05-23. PMID:12717420. |
here, we report that thap1 is a novel nuclear proapoptotic factor associated with pml nbs, which potentiates both serum withdrawal- and tnf alpha-induced apoptosis, and interacts with prostate-apoptosis-response-4 (par-4), a well characterized proapoptotic factor, previously linked to prostate cancer and neurodegenerative diseases. |
2003-05-23 |
2023-08-12 |
Not clear |
| Seema S Ahuja, Shujie Zhao, Teresita Bellido, Lilian I Plotkin, Fabio Jimenez, Lynda F Bonewal. CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4. Endocrinology. vol 144. issue 5. 2003-05-22. PMID:12697681. |
in three different assays for apoptosis, including trypan blue exclusion, changes in nuclear morphology, and fluorescence-activated cell sorting staining for annexin v/propidium iodide, cd40l significantly inhibited apoptosis of mlo-y4 cells induced by dexamethasone, tnf alpha, or etoposide. |
2003-05-22 |
2023-08-12 |
Not clear |