| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chenggang Li, Baoqiang Guo, Shigang Ding, Carlos Rius, Carmen Langa, Pat Kumar, Carmelo Bernabeu, Shant Kuma. TNF alpha down-regulates CD105 expression in vascular endothelial cells: a comparative study with TGF beta 1. Anticancer research. vol 23. issue 2B. 2003-07-25. PMID:12820370. |
the pro-inflammatory cytokine, tnf alpha, and anti-inflammatory cytokine, tgf beta 1, regulate multiple cellular processes such as proliferation, differentiation and apoptosis. |
2003-07-25 |
2023-08-12 |
human |
| Songyi Han, Kwiyeom Yoon, Kyunghye Lee, Kyunghee Kim, Hyunduk Jang, Na Kyung Lee, Kichul Hwang, Soo Young Le. TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors. Biochemical and biophysical research communications. vol 305. issue 4. 2003-07-24. PMID:12767899. |
tnf-related weak inducer of apoptosis receptor, a tnf receptor superfamily member, activates nf-kappa b through tnf receptor-associated factors. |
2003-07-24 |
2023-08-12 |
Not clear |
| Songyi Han, Kwiyeom Yoon, Kyunghye Lee, Kyunghee Kim, Hyunduk Jang, Na Kyung Lee, Kichul Hwang, Soo Young Le. TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors. Biochemical and biophysical research communications. vol 305. issue 4. 2003-07-24. PMID:12767899. |
tnf-related weak inducer of apoptosis (tweak) is a member of the tnf ligand family that induces angiogenesis in vivo. |
2003-07-24 |
2023-08-12 |
Not clear |
| Sébastien Vallée, Francis Fouchier, Patricia Brémond, Claudette Briand, Jacques Marvaldi, Serge Champio. Insulin-like growth factor-1 downregulates nuclear factor kappa B activation and upregulates interleukin-8 gene expression induced by tumor necrosis factor alpha. Biochemical and biophysical research communications. vol 305. issue 4. 2003-07-24. PMID:12767906. |
this event may be important for the cross-talk between igf-1- and tnf alpha-mediated pathways leading to the control of inflammatory processes and the decision concerning apoptosis or cell survival. |
2003-07-24 |
2023-08-12 |
Not clear |
| Dara Ditsworth, Margaret A Priestley, Andreas W Loepke, Chandra Ramamoorthy, John McCann, Lauren Staple, C Dean Kurt. Apoptotic neuronal death following deep hypothermic circulatory arrest in piglets. Anesthesiology. vol 98. issue 5. 2003-07-22. PMID:12717133. |
caspases, cytochrome c, tumor necrosis factor (tnf), and fas play a role in apoptosis in many ischemic models. |
2003-07-22 |
2023-08-12 |
Not clear |
| Q Yao, S Wang, A Gambotto, J C Glorioso, C H Evans, P D Robbins, S C Ghivizzani, T J Oligin. Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium. Gene therapy. vol 10. issue 12. 2003-07-21. PMID:12776164. |
in this study, we examined the ability to eliminate the hyperplastic synovium by adenoviral-mediated gene transfer of human tnf-related apoptosis-inducing ligand (trail), a member of the tnf family that is able to induce apoptosis through interaction with receptors containing death domains, dr4 and dr5. |
2003-07-21 |
2023-08-12 |
human |
| Chong-Shan Shi, John H Kehr. Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2). The Journal of biological chemistry. vol 278. issue 17. 2003-07-16. PMID:12591926. |
tumor necrosis factor (tnf)-induced activation of apoptosis signal-regulating kinase 1 (ask1) and germinal center kinases (gcks) and the subsequent activation of stress-activated protein kinases (sapks and c-jun nh(2)-terminal kinases) requires tnf receptor-associated factor 2 (traf2). |
2003-07-16 |
2023-08-12 |
Not clear |
| U Ramp, E Caliskan, C Mahotka, A Krieg, S Heikaus, H E Gabbert, C D Gerhar. Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage. British journal of cancer. vol 88. issue 11. 2003-07-15. PMID:12771998. |
tnf-related apoptosis-inducing ligand (trail apo-2l) is a member of the tnf family and induces apoptosis in cancer cells without affecting most non-neoplastic cells. |
2003-07-15 |
2023-08-12 |
human |
| Ramkumar Menon, Salvatore J Lombardi, Stephen J Fortunat. TNF-alpha promotes caspase activation and apoptosis in human fetal membranes. Journal of assisted reproduction and genetics. vol 19. issue 4. 2003-07-11. PMID:12036088. |
this study examines the role of tnf in promoting fetal membrane apoptosis. |
2003-07-11 |
2023-08-12 |
human |
| Sabiha Abbas, Yousef Abu-Ame. Dominant-negative IkappaB facilitates apoptosis of osteoclasts by tumor necrosis factor-alpha. The Journal of biological chemistry. vol 278. issue 22. 2003-07-10. PMID:12637573. |
however, administration of dn-ikappab to cultures prior to tnf exposure averts the osteoclastogenic effect of tnf into apoptosis. |
2003-07-10 |
2023-08-12 |
Not clear |
| Sabiha Abbas, Yousef Abu-Ame. Dominant-negative IkappaB facilitates apoptosis of osteoclasts by tumor necrosis factor-alpha. The Journal of biological chemistry. vol 278. issue 22. 2003-07-10. PMID:12637573. |
taken together, these findings suggest that under conditions of nf-kappab inactivity levels of pro-survival factors are diminished, which in turn facilitates tnf induction of pro-apoptotic factors leading to apoptosis. |
2003-07-10 |
2023-08-12 |
Not clear |
| Klaus-Peter Wandinger, Jan D Lünemann, Oliver Wengert, Judith Bellmann-Strobl, Orhan Aktas, Alexandra Weber, Eva Grundström, Stefan Ehrlich, Klaus-D Wernecke, Hans-Dieter Volk, Frauke Zip. TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis. Lancet (London, England). vol 361. issue 9374. 2003-07-10. PMID:12814715. |
we aimed to assess the functional relevance of tumour necrosis factor (tnf)-related apoptosis inducing ligand (trail), which is upregulated on incubation with interferon beta, for clinical treatment response. |
2003-07-10 |
2023-08-12 |
Not clear |
| Jon B Klein, Guang-Wu Wang, Zhanxiang Zhou, Abdul Buridi, Y James Kan. Inhibition of tumor necrosis factor-alpha-dependent cardiomyocyte apoptosis by metallothionein. Cardiovascular toxicology. vol 2. issue 3. 2003-07-09. PMID:12665666. |
tumor necrosis factor-alpha (tnf) accumulates in the failing heart and causes myocyte apoptosis, but the mechanism of this action is unclear. |
2003-07-09 |
2023-08-12 |
mouse |
| Jon B Klein, Guang-Wu Wang, Zhanxiang Zhou, Abdul Buridi, Y James Kan. Inhibition of tumor necrosis factor-alpha-dependent cardiomyocyte apoptosis by metallothionein. Cardiovascular toxicology. vol 2. issue 3. 2003-07-09. PMID:12665666. |
the treatment of wildtype cardiomyocytes with tnf at 10 ng/ml induced apoptosis, as detected by terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling and confirmed by annexin v-fluorescein isothiocyanate binding. |
2003-07-09 |
2023-08-12 |
mouse |
| Norbert W Lutz, Margaret E Tome, Patrick J Cozzon. Early changes in glucose and phospholipid metabolism following apoptosis induction by IFN-gamma/TNF-alpha in HT-29 cells. FEBS letters. vol 544. issue 1-3. 2003-07-07. PMID:12782301. |
apoptosis was induced by co-incubation with 200 u/ml tumor necrosis factor (tnf)-alpha for 4, 8 or 15 h, after sensitization with 500 u/ml interferon (ifn)-gamma for 7 h. perchloric acid extracts were analyzed by (1)h and (31)p nuclear magnetic resonance (nmr) spectroscopy. |
2003-07-07 |
2023-08-12 |
human |
| Vladimir N Ivanov, Anindita Bhoumik, Ze'ev Rona. Death receptors and melanoma resistance to apoptosis. Oncogene. vol 22. issue 20. 2003-07-07. PMID:12789291. |
changes at genomic, transcriptional and post-translational levels of g-proteins and protein kinases (ras, b-raf) and their transcription factor effectors (c-jun, atf2, stat3 and nf-kappab) affects tnf, fas and trail receptors, which play important roles in acquiring melanoma's resistance to apoptosis. |
2003-07-07 |
2023-08-12 |
Not clear |
| Sharron A N Brown, Christine M Richards, Heather N Hanscom, Sheau-Line Y Feng, Jeffrey A Winkle. The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. The Biochemical journal. vol 371. issue Pt 2. 2003-07-03. PMID:12529173. |
the human fn14 protein was recently identified as a cell-surface receptor for the tumour necrosis factor (tnf) superfamily member named tweak (tnf-like weak inducer of apoptosis). |
2003-07-03 |
2023-08-12 |
human |
| Cristina Muñoz-Pinedo, Carmen Ruiz-Ruiz, Carmen Ruiz de Almodóvar, Carmen Palacios, Abelardo López-Riva. Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing. The Journal of biological chemistry. vol 278. issue 15. 2003-07-03. PMID:12556444. |
we show that both substitution of glucose for pyruvate and treatment with 2-deoxyglucose enhanced apoptosis induced by tumor necrosis factor (tnf)-alpha, cd95 agonistic antibody, and tnf-related apoptosis-inducing ligand (trail). |
2003-07-03 |
2023-08-12 |
human |
| Veronica Galvan, Anna Logvinova, Sabina Sperandio, Hidenori Ichijo, Dale E Bredese. Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1). The Journal of biological chemistry. vol 278. issue 15. 2003-07-03. PMID:12556535. |
apoptosis signal-regulating kinase 1 (ask1) is a map kinase kinase kinase (mapkkk) that is required for c-jun n-terminal kinase (jnk) and p38 activation in response to fas and tumor necrosis factor (tnf) receptor stimulation, and for oxidative stress- and tnfalpha-induced apoptosis. |
2003-07-03 |
2023-08-12 |
Not clear |
| Hilmar Quentmeier, Julia Reinhardt, Margarete Zaborski, Hans G Drexle. Granulocyte-macrophage colony-stimulating factor: inhibitor of tumor necrosis factor-induced apoptosis. Leukemia research. vol 27. issue 6. 2003-07-01. PMID:12648514. |
tumor necrosis factor (tnf) can induce proliferation as well as apoptosis in acute myeloid leukemia (aml)-derived cells. |
2003-07-01 |
2023-08-12 |
Not clear |