| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dae Jun Jung, Jin Jong Bong, Myunggi Bai. Extracellular proteinase inhibitor-accelerated apoptosis is associated with B cell activating factor in mammary epithelial cells. Experimental cell research. vol 292. issue 1. 2004-02-27. PMID:14720511. |
furthermore, we have found that the expi-accelerated apoptosis is mediated via baff receptor among three known baff receptors: baff receptor, tumor necrosis factor (tnf) receptor homologue taci (transmembrane activator and caml-interactor), and bcma (another tnfr homologue, b cell maturation antigen). |
2004-02-27 |
2023-08-12 |
Not clear |
| E A Martynova, E V Poddubskaia, E P Polosukhina, S V Klimov. [TNF-induced apoptosis and necrosis in myeloleukemia cells HL-60 is regulated by reactive oxygen metabolites depending on a cell cycle phase]. Biomeditsinskaia khimiia. vol 49. issue 1. 2004-02-23. PMID:14569872. |
tnf is the known death receptor ligand which induce apoptosis and necrosis. |
2004-02-23 |
2023-08-12 |
Not clear |
| E A Martynova, E V Poddubskaia, E P Polosukhina, S V Klimov. [TNF-induced apoptosis and necrosis in myeloleukemia cells HL-60 is regulated by reactive oxygen metabolites depending on a cell cycle phase]. Biomeditsinskaia khimiia. vol 49. issue 1. 2004-02-23. PMID:14569872. |
pretreatment of these cells with exogenous bacterial sphingomyelinase (smase) potentiates tnf-alpha induced apoptosis only, suggesting the role of ceramide from sphingomyelin cycle in tnf signaling pathways of apoptosis. |
2004-02-23 |
2023-08-12 |
Not clear |
| M Kimura, M Haisa, H Uetsuka, M Takaoka, T Ohkawa, R Kawashima, T Yamatsuji, M Gunduz, Y Kaneda, N Tanaka, Y Naomot. TNF combined with IFN-alpha accelerates NF-kappaB-mediated apoptosis through enhancement of Fas expression in colon cancer cells. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761580. |
tnf combined with ifn-alpha accelerates nf-kappab-mediated apoptosis through enhancement of fas expression in colon cancer cells. |
2004-02-19 |
2023-08-12 |
human |
| I Petak, R Vernes, K S Szucs, M Anozie, K Izeradjene, L Douglas, D M Tillman, D C Phillips, J A Houghto. A caspase-8-independent component in TRAIL/Apo-2L-induced cell death in human rhabdomyosarcoma cells. Cell death and differentiation. vol 10. issue 6. 2004-02-19. PMID:12761581. |
tumor necrosis factor related apoptosis inducing ligand (trail) belongs to the tumor necrosis factor (tnf) family of death-inducing ligands, and signaling downstream of trail ligation to its receptor(s) remains to be fully elucidated. |
2004-02-19 |
2023-08-12 |
human |
| Gérard Socié, Jean-Yves Mary, Marc Lemann, Marjan Daneshpouy, Philippe Guardiola, Véronique Meignin, Lionel Ades, Hélène Esperou, Patricia Ribaud, Agnés Devergie, Eliane Gluckman, Jean-Claude Ameisen, Anne Jani. Prognostic value of apoptotic cells and infiltrating neutrophils in graft-versus-host disease of the gastrointestinal tract in humans: TNF and Fas expression. Blood. vol 103. issue 1. 2004-02-17. PMID:12881313. |
in rodents both tumor necrosis factor (tnf) and fas-dependent apoptosis have been shown to play a major role in gvhd lesions, but data in humans on tnf and fas in situ expression are scarce. |
2004-02-17 |
2023-08-12 |
Not clear |
| Izabela Młnarczuk, Paweł Mróz, Grazyna Hoser, Dominika Nowis, Łukasz P Biały, Halina Ziemba, Tomasz Grzela, Wojciech Feleszko, Jacek Malejczyk, Cezary Wójcik, Marek Jakóbisiak, Jakub Goła. AAF-cmk sensitizes tumor cells to trail-mediated apoptosis. Leukemia research. vol 28. issue 1. 2004-02-17. PMID:14630081. |
altogether, our studies indicate that aaf-cmk might effectively sensitize human leukemia cells to apoptosis induced by trail and tnf. |
2004-02-17 |
2023-08-12 |
human |
| Emese Mezosi, Su He Wang, Saho Utsugi, Laszlo Bajnok, James D Bretz, Paul G Gauger, Norman W Thompson, James R Bake. Interleukin-1beta and tumor necrosis factor (TNF)-alpha sensitize human thyroid epithelial cells to TNF-related apoptosis-inducing ligand-induced apoptosis through increases in procaspase-7 and bid, and the down-regulation of p44/42 mitogen-activated protein kinase activity. The Journal of clinical endocrinology and metabolism. vol 89. issue 1. 2004-02-11. PMID:14715858. |
interleukin-1beta and tumor necrosis factor (tnf)-alpha sensitize human thyroid epithelial cells to tnf-related apoptosis-inducing ligand-induced apoptosis through increases in procaspase-7 and bid, and the down-regulation of p44/42 mitogen-activated protein kinase activity. |
2004-02-11 |
2023-08-12 |
human |
| Mani Alikhani, Zoubin Alikhani, Hongbing He, Rongkun Liu, Barbara I Popek, Dana T Grave. Lipopolysaccharides indirectly stimulate apoptosis and global induction of apoptotic genes in fibroblasts. The Journal of biological chemistry. vol 278. issue 52. 2004-02-10. PMID:14551216. |
in vitro studies demonstrated that lps did not induce apoptosis of fibroblasts, whereas tumor necrosis factor (tnf) did. |
2004-02-10 |
2023-08-12 |
mouse |
| Mani Alikhani, Zoubin Alikhani, Hongbing He, Rongkun Liu, Barbara I Popek, Dana T Grave. Lipopolysaccharides indirectly stimulate apoptosis and global induction of apoptotic genes in fibroblasts. The Journal of biological chemistry. vol 278. issue 52. 2004-02-10. PMID:14551216. |
moreover, pre-treatment of cells with tnf greatly enhanced apoptosis induced by a second stimulation with tnf 24 h later, suggesting that the global induction of pro-apoptotic genes was functionally significant. |
2004-02-10 |
2023-08-12 |
mouse |
| Mani Alikhani, Zoubin Alikhani, Hongbing He, Rongkun Liu, Barbara I Popek, Dana T Grave. Lipopolysaccharides indirectly stimulate apoptosis and global induction of apoptotic genes in fibroblasts. The Journal of biological chemistry. vol 278. issue 52. 2004-02-10. PMID:14551216. |
thus, lps acts to modulate the expression of a large number of genes that favor apoptosis of fibroblastic cells that is dependent upon activation of caspase-8 and is largely mediated by tnf. |
2004-02-10 |
2023-08-12 |
mouse |
| Junko Yasuda, Wakako Nishioka, Akikazu Sakudo, Sachiko Yama, Ruka Setoguchi, Keiichi Saeki, Yoshitsugu Matsumoto, Akira Awaya, Takashi Onoder. Suppressor mechanism of serum thymic factor on tumor necrosis factor-alpha-induced apoptosis in the mouse pancreatic beta-cell line. Biochemical and biophysical research communications. vol 311. issue 2. 2004-02-10. PMID:14592444. |
expression of tnf receptor i, inducible form of nitric oxide synthase (inos), interleukin-1 beta-converting enzyme (ice), bcl-2, and nuclear factor kappa b (nf-kappa b) was analyzed by reverse transcriptase-polymerase chain reaction to investigate the suppressor mechanism of fts on tnf-alpha-induced apoptosis. |
2004-02-10 |
2023-08-12 |
mouse |
| Klaus Pfeffe. Biological functions of tumor necrosis factor cytokines and their receptors. Cytokine & growth factor reviews. vol 14. issue 3-4. 2004-02-09. PMID:12787558. |
tumor necrosis factor (tnf; formerly known as tnfalpha) and lymphotoxin (lt)alpha, originally characterized by their ability to induce tumor cell apoptosis and cachexia, are now considered as central mediators of a broad range of biological activities. |
2004-02-09 |
2023-08-12 |
mouse |
| Steven R Wiley, Jeffrey A Winkle. TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor. Cytokine & growth factor reviews. vol 14. issue 3-4. 2004-02-09. PMID:12787562. |
the cytokine tumor necrosis factor-like weak inducer of apoptosis (tweak) was initially described as a member of the tumor necrosis factor (tnf) superfamily in 1997. |
2004-02-09 |
2023-08-12 |
human |
| Alexandru Almasan, Avi Ashkenaz. Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy. Cytokine & growth factor reviews. vol 14. issue 3-4. 2004-02-09. PMID:12787570. |
apo2 ligand or tumor necrosis factor (tnf)-related apoptosis-inducing ligand (apo2l/trail) is one of several members of the tnf gene superfamily that induce apoptosis through engagement of death receptors. |
2004-02-09 |
2023-08-12 |
Not clear |
| Rodolfo Sacco, Takeya Tsutsumi, Ryosuke Suzuki, Motoyuki Otsuka, Hideki Aizaki, Shinichiro Sakamoto, Mami Matsuda, Naohiko Seki, Yoshiharu Matsuura, Tatsuo Miyamura, Tetsuro Suzuk. Antiapoptotic regulation by hepatitis C virus core protein through up-regulation of inhibitor of caspase-activated DNase. Virology. vol 317. issue 1. 2004-02-03. PMID:14675622. |
by transcriptional profiling, we identified differentially expressed genes, some of which are involved in cell growth or apoptosis such as inhibitor of caspase-activated dnase (icad), defender against cell death 1, tumor necrosis factor (tnf) receptor 1, and cytochrome c oxidase subunit viii. |
2004-02-03 |
2023-08-12 |
human |
| Noboru Yamaguchi, Chie Kubo, Yoshikazu Masuhiro, Edward T Lally, Toshihiko Koga, Shigemasa Hanazaw. Tumor necrosis factor alpha enhances Actinobacillus actinomycetemcomitans leukotoxin-induced HL-60 cell apoptosis by stimulating lymphocyte function-associated antigen 1 expression. Infection and immunity. vol 72. issue 1. 2004-02-02. PMID:14688105. |
taken together, the results of the present study indicate that tnf-alpha acts as a potent stimulator of ltx-induced hl-60 cell apoptosis via tnf receptor 1-mediated upregulation of lfa-1 expression. |
2004-02-02 |
2023-08-12 |
human |
| Francis Ka-Ming Chan, Joanna Shisler, Jacqueline G Bixby, Martin Felices, Lixin Zheng, Michael Appel, Jan Orenstein, Bernard Moss, Michael J Lenard. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. The Journal of biological chemistry. vol 278. issue 51. 2004-01-30. PMID:14532286. |
members of the tumor necrosis factor (tnf) receptor (tnfr) superfamily are potent regulators of apoptosis, a process that is important for the maintenance of immune homeostasis. |
2004-01-30 |
2023-08-12 |
mouse |
| Rey Paglinawan, Ursula Malipiero, Ralph Schlapbach, Karl Frei, Walter Reith, Adriano Fontan. TGFbeta directs gene expression of activated microglia to an anti-inflammatory phenotype strongly focusing on chemokine genes and cell migratory genes. Glia. vol 44. issue 3. 2004-01-30. PMID:14603463. |
the focus of tgfbeta inhibition is observed to be directed in genes involved in chemotaxis (il-15, cxcl1, cxcl2, ccl3, ccl4, ccl5, ccl9), chemokine receptors (ccr5, ccr9), lif receptor, and fpr2, and on genes mediating cell migration (mmp9, mmp13, macmarcks, endothelin receptor b, ena/vasp, gas7), apoptosis (fas, tnf, tnf receptor, caspase-1 and -11), and host response to infection (toll-like receptor 6, mx-1, and marco). |
2004-01-30 |
2023-08-12 |
Not clear |
| B Wielockx, C Liber. Serine proteases of the fibrinolysis pathway are not involved in lethal hepatitis and fibrinogen breakdown induced by tumor necrosis factor. Cytokine. vol 21. issue 6. 2004-01-29. PMID:12824001. |
tumor necrosis factor (tnf) plays a key role in several types of fulminant and acute hepatitis, and induces massive apoptosis and necrosis of hepatocytes. |
2004-01-29 |
2023-08-12 |
mouse |