Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xiu-Xian Wu, Osamu Ogawa, Yoshiyuki Kakeh. TRAIL and chemotherapeutic drugs in cancer therapy. Vitamins and hormones. vol 67. 2004-07-07. PMID:15110186. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail/apo2l) is a recently identified member of the tnf ligand family that selectively induces apoptosis in tumor cells in vitro and in vivo but not in most normal cells. |
2004-07-07 |
2023-08-12 |
Not clear |
Christine Odoux, Andreas Alber. Additive effects of TRAIL and paclitaxel on cancer cells: implications for advances in cancer therapy. Vitamins and hormones. vol 67. 2004-07-07. PMID:15110187. |
together, pa and trail lead to tumor regression in in vivo therapy and induce apoptosis through the interaction of tnf family death receptors, caspase activation, and?or cytochrome c release from mitochondria. |
2004-07-07 |
2023-08-12 |
Not clear |
Rongfa Bu, Christopher W Borysenko, Yanan Li, Lihuan Cao, Afsie Sabokbar, Harry C Blai. Expression and function of TNF-family proteins and receptors in human osteoblasts. Bone. vol 33. issue 5. 2004-07-06. PMID:14623051. |
however, in media supporting osteoblast-like phenotype, apoptosis was induced by anti-fas or tnf, in contrast to other studies with human osteoblasts. |
2004-07-06 |
2023-08-12 |
human |
Dalliah Black, Mark A Bird, Melissa Hayden, Laura W Schrum, Patricia Lange, Charles Samson, Etsuro Hatano, Richard A Rippe, David A Brenner, Kevin E Behrn. TNF alpha-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein. Surgery. vol 135. issue 6. 2004-07-01. PMID:15179368. |
tnf alpha-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein. |
2004-07-01 |
2023-08-12 |
Not clear |
C Choi, K-K Hwang, C Cha. Classical swine fever virus induces tumor necrosis factor-alpha and lymphocyte apoptosis. Archives of virology. vol 149. issue 5. 2004-06-25. PMID:15098104. |
the expression of tumor necrosis factor (tnf)-alpha and apoptosis was studied in lymph nodes from pigs infected with classical swine fever virus (csfv). |
2004-06-25 |
2023-08-12 |
Not clear |
Hongri Xu, Atsushi Okamoto, Jiro Ichikawa, Takashi Ando, Kachio Tasaka, Keisuke Masuyama, Hideoki Ogawa, Hideo Yagita, Ko Okumura, Atsuhito Naka. TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF. Biochemical and biophysical research communications. vol 318. issue 2. 2004-06-25. PMID:15120617. |
tnf-like weak inducer of apoptosis (tweak), a member of the tumor necrosis factor (tnf) family, is a multifunctional cytokine that regulates cellular proliferation, angiogenesis, inflammation, and apoptosis. |
2004-06-25 |
2023-08-12 |
human |
Long Jin, Atsuhito Nakao, Masafumi Nakayama, Noriko Yamaguchi, Yuko Kojima, Nobuhiro Nakano, Ryoji Tsuboi, Ko Okumura, Hideo Yagita, Hideoki Ogaw. Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes. The Journal of investigative dermatology. vol 122. issue 5. 2004-06-25. PMID:15140220. |
tnf-like weak inducer of apoptosis (tweak), a member of the tumor necrosis factor (tnf) family, is a multifunctional cytokine that regulate cellular proliferation, angiogenesis, inflammation, and apoptosis. |
2004-06-25 |
2023-08-12 |
human |
Masahiro Minagawa, Qinggao Deng, Zhang-Xu Liu, Hidekazu Tsukamoto, Gunther Denner. Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-alpha during alcohol consumption. Gastroenterology. vol 126. issue 5. 2004-06-23. PMID:15131799. |
natural killer t cells are mediators of important regulator and effector functions making use of fas and tumor necrosis factor (tnf)-alpha in apoptosis induction. |
2004-06-23 |
2023-08-12 |
Not clear |
Bing He, Amy Chadburn, Erin Jou, Elaine J Schattner, Daniel M Knowles, Andrea Cerutt. Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 5. 2004-06-21. PMID:14978135. |
lymphoma b cells evade apoptosis through the tnf family members baff/blys and april. |
2004-06-21 |
2023-08-12 |
Not clear |
Myung-Shik Lee, Ja-Young Kim, Sun Young Par. Resistance of rho(0) cells against apoptosis. Annals of the New York Academy of Sciences. vol 1011. 2004-06-17. PMID:15126292. |
trail, a recently identified member of the tnf family with cytotoxicity on a wide variety of transformed cells, killed sk-hep1 cells with characteristic features of apoptosis such as dna fragmentation, sub-g1 ploidy peak, and cytochrome c translocation. |
2004-06-17 |
2023-08-12 |
Not clear |
V Duverger, A-M Murphy, D Sheehan, K England, T G Cotter, I Hayes, F J Murph. The anticancer drug mithramycin A sensitises tumour cells to apoptosis induced by tumour necrosis factor (TNF). British journal of cancer. vol 90. issue 10. 2004-06-16. PMID:15138489. |
the anticancer drug mithramycin a sensitises tumour cells to apoptosis induced by tumour necrosis factor (tnf). |
2004-06-16 |
2023-08-12 |
Not clear |
David W Draper, Virginia G Harris, Carolyn A Culver, Scott M Laste. Calcium and its role in the nuclear translocation and activation of cytosolic phospholipase A2 in cells rendered sensitive to TNF-induced apoptosis by cycloheximide. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 4. 2004-06-15. PMID:14764712. |
as our model, we used a murine fibroblast cell line (c3ha) that was induced to undergo apoptosis by a combination of tnf and cycloheximide. |
2004-06-15 |
2023-08-12 |
Not clear |
Patrick N Cunningham, Ying Wang, Rongqing Guo, Gang He, Richard J Quig. Role of Toll-like receptor 4 in endotoxin-induced acute renal failure. Journal of immunology (Baltimore, Md. : 1950). vol 172. issue 4. 2004-06-15. PMID:14764737. |
c3h/hej mice released no tnf into the circulation at 2 h (0.00 vs 1.24 +/- 0.16 ng/ml), had less renal neutrophil infiltration (6.4 +/- 1.0 vs 11.4 +/- 1.3 neutrophils per high power field), and less renal apoptosis, as assessed by dna laddering. |
2004-06-15 |
2023-08-12 |
mouse |
Annie Abadie, Juana Wietzerbi. Involvement of TNF-related apoptosis-inducing ligand (TRAIL) induction in interferon gamma-mediated apoptosis in Ewing tumor cells. Annals of the New York Academy of Sciences. vol 1010. 2004-06-15. PMID:15033706. |
it was shown recently that ewing cells undergo apoptosis upon treatment with recombinant trail (tnf-related apoptosis inducing ligand), a member of the tnf family. |
2004-06-15 |
2023-08-12 |
Not clear |
Annie Abadie, Juana Wietzerbi. Involvement of TNF-related apoptosis-inducing ligand (TRAIL) induction in interferon gamma-mediated apoptosis in Ewing tumor cells. Annals of the New York Academy of Sciences. vol 1010. 2004-06-15. PMID:15033706. |
the results reported here are consistent with the notion that cell-associated and secreted trail contribute in an autocrine or paracrine manner to the triggering of ewing cell apoptosis induced by ifn gamma alone or combined with ifn alpha or tnf. |
2004-06-15 |
2023-08-12 |
Not clear |
Claudio Napol. Oxidation of LDL, atherogenesis, and apoptosis. Annals of the New York Academy of Sciences. vol 1010. 2004-06-15. PMID:15033814. |
a plethora of studies in cultured cells have established that oxidized low-density lipoprotein (oxldl) may enhance arterial apoptosis that involves both mitochondrial and death receptor pathways (fas/fasl, tnf receptors i and ii), thereby activating caspase cascade and other proteases. |
2004-06-15 |
2023-08-12 |
Not clear |
Jun Zhang, Liang-Guo Xu, Ke-Jun Han, Hong-Bing Sh. Identification of a ZU5 and death domain-containing inhibitor of NF-kappaB. The Journal of biological chemistry. vol 279. issue 17. 2004-06-10. PMID:14769797. |
consistent with its role in inhibition of nf-kappab-dependent transcription, zud sensitized cells to apoptosis induced by tnf and the tnf-related apoptosis-inducing ligand (trail). |
2004-06-10 |
2023-08-12 |
Not clear |
Michael Lagunoff, Patrick Andrew Carrol. Inhibition of apoptosis by the gamma-herpesviruses. International reviews of immunology. vol 22. issue 5-6. 2004-06-01. PMID:12959751. |
virally encoded genes inhibit the activation of caspase-8 by the tnf receptor and fas; activate nf-kappab to increase expression of antiapoptotic genes; inhibit interferon response; bind to p53, thereby blocking p53 dependent apoptosis; and interact with other pro- and antiapoptotic cellular genes. |
2004-06-01 |
2023-08-12 |
human |
R Joel Low. Influenza virus induction of apoptosis by intrinsic and extrinsic mechanisms. International reviews of immunology. vol 22. issue 5-6. 2004-06-01. PMID:12959753. |
influenza virus also has important exocrine paracrine effects, which are likely mediated via tnf family ligands and oxygen, free radicals capable of inducing apoptosis. |
2004-06-01 |
2023-08-12 |
Not clear |
Yasunari Takada, Sujay Singh, Bharat B Aggarwa. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. The Journal of biological chemistry. vol 279. issue 15. 2004-06-01. PMID:14711835. |
suppression of nf-kappab by ptd-p65-p1 enhanced the apoptosis induced by tnf and chemotherapeutic agents. |
2004-06-01 |
2023-08-12 |
Not clear |