| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Drew L Lichtenstein, Konstantin Doronin, Karoly Toth, Mohan Kuppuswamy, William S M Wold, Ann E Tollefso. Adenovirus E3-6.7K protein is required in conjunction with the E3-RID protein complex for the internalization and degradation of TRAIL receptor 2. Journal of virology. vol 78. issue 22. 2004-11-23. PMID:15507617. |
among these immunomodulatory proteins, the receptor internalization and degradation (rid) protein complex, which is composed of the ridalpha (formerly e3-10.4k) and ridbeta (formerly e3-14.5k) subunits, stimulates the internalization and degradation of certain members of the tumor necrosis factor (tnf) receptor superfamily, thus blocking apoptosis initiated by fas and tnf-related apoptosis-inducing ligand (trail). |
2004-11-23 |
2023-08-12 |
Not clear |
| Hideki Fujii, Shuichi Seki, Kazuki Nakatani, Kazuo Ikeda, Masaru Ikemoto, Yuji Nakajima, Tetsuo Arakawa, Kenji Kaned. Localization of lymphocyte apoptosis in murine lymphoid tissues after stimulation of natural killer T cells with alpha-galactosylceramide. Archives of histology and cytology. vol 66. issue 5. 2004-11-22. PMID:15018142. |
alpha-galcer-induced lymphocyte apoptosis was seen in tumor-necrosis factor (tnf)-deficient mice as well, but was not in lpr/lpr (fas-deficient) or gld/gld (fas ligand-deficient) mice. |
2004-11-22 |
2023-08-12 |
mouse |
| Uday Kishore, Christine Gaboriaud, Patrick Waters, Annette K Shrive, Trevor J Greenhough, Kenneth B M Reid, Robert B Sim, Gerard J Arlau. C1q and tumor necrosis factor superfamily: modularity and versatility. Trends in immunology. vol 25. issue 10. 2004-11-19. PMID:15364058. |
the members of this newly designated 'c1q and tnf superfamily' are involved in processes as diverse as host defense, inflammation, apoptosis, autoimmunity, cell differentiation, organogenesis, hibernation and insulin-resistant obesity. |
2004-11-19 |
2023-08-12 |
Not clear |
| Sita Aggarwal, Yasunari Takada, Abner M Mhashilkar, Kerry Sieger, Sunil Chada, Bharat B Aggarwa. Melanoma differentiation-associated gene-7/IL-24 gene enhances NF-kappa B activation and suppresses apoptosis induced by TNF. Journal of immunology (Baltimore, Md. : 1950). vol 173. issue 7. 2004-11-15. PMID:15383566. |
melanoma differentiation-associated gene-7/il-24 gene enhances nf-kappa b activation and suppresses apoptosis induced by tnf. |
2004-11-15 |
2023-08-12 |
human |
| Sanjeev Shukla, Sanjay Gupt. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 10. issue 9. 2004-11-10. PMID:15131058. |
development of androgen independence and resistance to apoptosis in prostate cancer are often correlated with high levels of serum tumor necrosis factor (tnf)-alpha in these patients. |
2004-11-10 |
2023-08-12 |
human |
| Stéphanie Plenchette, Séverine Cathelin, Cédric Rébé, Sophie Launay, Sylvain Ladoire, Olivier Sordet, Tibor Ponnelle, Najet Debili, Thi-Hai Phan, Rose-Ann Padua, Laurence Dubrez-Daloz, Eric Solar. Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event. Blood. vol 104. issue 7. 2004-11-04. PMID:15187025. |
the caspase inhibitor and ring finger-containing protein cellular inhibitor of apoptosis protein 1 (c-iap1) has been shown to be involved in both apoptosis inhibition and signaling by members of the tumor necrosis factor (tnf) receptor family. |
2004-11-04 |
2023-08-12 |
mouse |
| Charles Dudognon, Frédéric Pendino, Josette Hillion, Anne Saumet, Michel Lanotte, Evelyne Ségal-Bendirdjia. Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance. Oncogene. vol 23. issue 45. 2004-11-02. PMID:15326479. |
here, we show that overexpression of the catalytic subunit of telomerase (htert) protects a maturation-resistant acute promyelocytic leukemia (apl) cell line from apoptosis induced by the tumor necrosis factor (tnf) or tnf-related apoptosis-inducing ligand (trail) and not from apoptosis induced by chemotherapeutic drugs such as etoposide or cisplatin. |
2004-11-02 |
2023-08-12 |
human |
| Monika Podhoreck. [Apoptosis in pathogenesis of B-cell chronic lymphocytic leukemia]. Postepy higieny i medycyny doswiadczalnej (Online). vol 58. 2004-10-25. PMID:15224009. |
il-4, il-2, ifn-gamma, and tnf are proven inhibitors, while il-5 and il-10 are inducers of apoptosis of these cells. |
2004-10-25 |
2023-08-12 |
Not clear |
| Yasunari Takada, Xianjun Fang, Md Saha Jamaluddin, Douglas D Boyd, Bharat B Aggarwa. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. The Journal of biological chemistry. vol 279. issue 38. 2004-10-25. PMID:15252041. |
tnf induced expression of the nf-kappab-regulated gene products cyclin d1, cox-2, mmp-9, survivin, iap 1, iap 2, bcl-x(l), bfl-1/a1, traf1, and flip in wild-type mouse embryonic fibroblasts but not in gsk-3beta(-/-) cells, and this correlated with potentiation of tnf-induced apoptosis as indicated by cell viability, annexin v staining, and caspase activation. |
2004-10-25 |
2023-08-12 |
mouse |
| Uwe Platzbecker, Peter Kurre, Philippe Guardiola, Jessica L Ward, Jerald P Radich, Hans-Peter Kiem, H Joachim Dee. Fanconi anemia type C-deficient hematopoietic cells are resistant to TRAIL (TNF-related apoptosis-inducing ligand)-induced cleavage of pro-caspase-8. Experimental hematology. vol 32. issue 9. 2004-10-21. PMID:15345282. |
the pathophysiology of bone marrow failure in fanconi anemia (fa) patients is thought to involve excessive apoptosis involving signaling triggered by fas ligation and tumor necrosis factor (tnf)-alpha, or interferon (ifn)-gamma exposure. |
2004-10-21 |
2023-08-12 |
Not clear |
| Kyoung-Han Choi, Hye Young Choi, Jae-Kyun Ko, Sung-Shin Park, Yong-Nyun Kim, Chul-Woo Ki. Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells. Journal of cellular biochemistry. vol 91. issue 2. 2004-10-19. PMID:14743399. |
in this study, we investigated mrna regulation of tnf family receptors and bcl-2 family members after treating the murine colon cancer cell line, ct26, with various apoptosis inducers. |
2004-10-19 |
2023-08-12 |
Not clear |
| Susan Moir, Angela Malaspina, Oxana K Pickeral, Eileen T Donoghue, Joshua Vasquez, Natalie J Miller, Surekha R Krishnan, Marie A Planta, John F Turney, J Shawn Justement, Shyamasundaran Kottilil, Mark Dybul, JoAnn M Mican, Colin Kovacs, Tae-Wook Chun, Charles E Birse, Anthony S Fauc. Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily. The Journal of experimental medicine. vol 200. issue 5. 2004-10-18. PMID:15353552. |
increased expression of the tumor necrosis factor (tnf) superfamily (tnfsf) receptor cd95 correlated with increased susceptibility to cd95-mediated apoptosis of cd21(low) b cells, which, in turn, correlated with hiv plasma viremia. |
2004-10-18 |
2023-08-12 |
human |
| Sayed Abdalla Abdalla, Hiroyuki Horiuchi, Shuichi Furusawa, Haruo Matsud. Molecular cloning and characterization of chicken tumor necrosis factor (TNF)-superfamily ligands, CD30L and TNF-related apoptosis inducing ligand (TRAIL). The Journal of veterinary medical science. vol 66. issue 6. 2004-10-12. PMID:15240938. |
molecular cloning and characterization of chicken tumor necrosis factor (tnf)-superfamily ligands, cd30l and tnf-related apoptosis inducing ligand (trail). |
2004-10-12 |
2023-08-12 |
human |
| Sayed Abdalla Abdalla, Hiroyuki Horiuchi, Shuichi Furusawa, Haruo Matsud. Molecular cloning and characterization of chicken tumor necrosis factor (TNF)-superfamily ligands, CD30L and TNF-related apoptosis inducing ligand (TRAIL). The Journal of veterinary medical science. vol 66. issue 6. 2004-10-12. PMID:15240938. |
cd30 ligand (cd30l) and tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) are members of the tnf-superfamily that have many important biological activities in cell proliferation and apoptotic death. |
2004-10-12 |
2023-08-12 |
human |
| Carmen Veríssima Ferreira, Carina L Bos, Henri H Versteeg, Giselle Z Justo, Nelson Durán, Maikel P Peppelenbosc. Molecular mechanism of violacein-mediated human leukemia cell death. Blood. vol 104. issue 5. 2004-10-04. PMID:15130948. |
hence, violacein represents the first member of a novel class of cytotoxic drugs mediating apoptosis of hl60 cells by way of the specific activation of tnf receptor 1. |
2004-10-04 |
2023-08-12 |
human |
| Yun-Ching Fu, Ching-Shiang Chi, Sui-Chu Yin, Betau Hwang, Yung-Tsung Chiu, Shih-Lan Hs. Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species-TNF alpha-caspase signaling pathway. Cardiovascular research. vol 62. issue 3. 2004-10-04. PMID:15158148. |
tumor necrosis factor-alpha (tnf), a well-known mediator that stimulates apoptosis, is not only produced by macrophages but also by cardiomyocytes. |
2004-10-04 |
2023-08-12 |
rat |
| Yun-Ching Fu, Ching-Shiang Chi, Sui-Chu Yin, Betau Hwang, Yung-Tsung Chiu, Shih-Lan Hs. Norepinephrine induces apoptosis in neonatal rat cardiomyocytes through a reactive oxygen species-TNF alpha-caspase signaling pathway. Cardiovascular research. vol 62. issue 3. 2004-10-04. PMID:15158148. |
until now, the role of tnf and its relationship to ros in ne-induced apoptosis of cardiomyocytes have never been investigated. |
2004-10-04 |
2023-08-12 |
rat |
| Barbara Vischioni, Giuseppe Giaccone, Simone W Span, Frank A E Kruyt, Jose A Rodrigue. Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2. Experimental cell research. vol 298. issue 2. 2004-10-04. PMID:15265700. |
ciap1 and ciap2 are two closely related members of inhibitor of apoptosis (iap) family that play a role both as caspase inhibitors and as mediators of tumor necrosis factor (tnf) receptor signaling. |
2004-10-04 |
2023-08-12 |
human |
| Simone Grethe, Mikko P S Ares, Tommy Andersson, M Isabella Pörn-Are. p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L). Experimental cell research. vol 298. issue 2. 2004-10-04. PMID:15265709. |
here, we investigated the involvement of p38 mapk in endothelial apoptosis induced by tumor necrosis factor alpha (tnf). |
2004-10-04 |
2023-08-12 |
Not clear |
| H W Zhao, S Y Hu, M W Barger, J K H Ma, V Castranova, J Y C M. Time-dependent apoptosis of alveolar macrophages from rats exposed to bleomycin: involvement of tnf receptor 2. Journal of toxicology and environmental health. Part A. vol 67. issue 17. 2004-09-30. PMID:15371238. |
time-dependent apoptosis of alveolar macrophages from rats exposed to bleomycin: involvement of tnf receptor 2. |
2004-09-30 |
2023-08-12 |
rat |