| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rajko Reljic, Carol Crawford, Stephen Challacombe, Juraj Ivany. Mouse IgA inhibits cell growth by stimulating tumor necrosis factor-alpha production and apoptosis of macrophage cell lines. International immunology. vol 16. issue 4. 2005-01-14. PMID:15039391. |
we demonstrated that iga binds to j774 cells, stimulates tumor necrosis factor (tnf)-alpha production and induces apoptosis which is not dependent on no or fas/cd95. |
2005-01-14 |
2023-08-12 |
mouse |
| Soo-Jung Park, Ching-Haung Wu, John D Gordon, Xiaoling Zhong, Armaghan Emami, Ahmad R Saf. Taxol induces caspase-10-dependent apoptosis. The Journal of biological chemistry. vol 279. issue 49. 2005-01-11. PMID:15452117. |
pretreating the cells with neutralizing antibodies to fas, tumor necrosis factor (tnf)-alpha receptor 1, or tnf-related apoptosis-inducing ligand receptors (dr4 and dr5) did not affect taxol-induced apoptosis, but transfection of the cells with a dominant negative fadd plasmid resulted in inhibition of taxol-induced apoptosis, revealing that taxol induces apoptosis independently of these death receptors but dependently on fadd. |
2005-01-11 |
2023-08-12 |
human |
| Cynthia A Ellison, Shannon A Natuik, Jacqie M M Fischer, Alan R McIntosh, Sheila A Scully, Eric J Bow, Dimitry M Danilenko, Kent T Hayglass, John G Gartne. Effect of recombinant human keratinocyte growth factor (rHuKGF) on the immunopathogenesis of intestinal graft-vs.-host disease induced without a preconditioning regimen. Journal of clinical immunology. vol 24. issue 2. 2005-01-04. PMID:15024187. |
lps augmented serum tnf alpha release and intestinal no production, but did not induce intestinal epithelial cell apoptosis, a phenomenon associated with acute gvhd. |
2005-01-04 |
2023-08-12 |
mouse |
| Wen-Horng Wang, Gérald Grégori, Ronald L Hullinger, Ourania M Andrisan. Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression. Molecular and cellular biology. vol 24. issue 23. 2005-01-04. PMID:15542843. |
sustained activation of p38 mitogen-activated protein kinase and c-jun n-terminal kinase pathways by hepatitis b virus x protein mediates apoptosis via induction of fas/fasl and tumor necrosis factor (tnf) receptor 1/tnf-alpha expression. |
2005-01-04 |
2023-08-12 |
Not clear |
| Chinatsu Kasuga, Tomohiko Ebata, Nobuhiko Kayagaki, Hideo Yagita, Makoto Hishii, Hajime Arai, Kiyoshi Sato, Ko Okumur. Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors. Cancer science. vol 95. issue 10. 2005-01-03. PMID:15504253. |
trail is a member of the tnf family, which selectively induces apoptosis in certain neoplastic cells, but not normal cells. |
2005-01-03 |
2023-08-12 |
human |
| Shishir Shishodia, Bharat B Aggarwa. Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis. The Journal of biological chemistry. vol 279. issue 45. 2004-12-28. PMID:15322087. |
in addition, guggulsterone decreased the expression of gene products involved in anti-apoptosis (iap1, xiap, bfl-1/a1, bcl-2, cflip, and survivin), proliferation (cyclin d1 and c-myc), and metastasis (mmp-9, cox-2, and vegf); this correlated with enhancement of apoptosis induced by tnf and chemotherapeutic agents. |
2004-12-28 |
2023-08-12 |
Not clear |
| Kathie A Mihindukulasuriya, Guisheng Zhou, Jun Qin, Tse-Hua Ta. Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation. The Journal of biological chemistry. vol 279. issue 45. 2004-12-28. PMID:15331607. |
protein phosphatase 4 (pp4; also named ppx or ppp4) is a pp2a-related protein serine/threonine phosphatase with important roles in a variety of cellular processes such as microtubule growth/organization, apoptosis, tumor necrosis factor (tnf)-alpha signaling, and activation of c-jun n-terminal kinase and nf-kappab. |
2004-12-28 |
2023-08-12 |
human |
| Paola Secchiero, Mauro Vaccarezza, Arianna Gonelli, Giorgio Zaul. TNF-related apoptosis-inducing ligand (TRAIL): a potential candidate for combined treatment of hematological malignancies. Current pharmaceutical design. vol 10. issue 29. 2004-12-27. PMID:15579063. |
tnf-related apoptosis-inducing ligand (trail) is a member of the tnf gene superfamily, which induces apoptosis through engagement of death receptors. |
2004-12-27 |
2023-08-12 |
Not clear |
| Paola Secchiero, Mauro Vaccarezza, Arianna Gonelli, Giorgio Zaul. TNF-related apoptosis-inducing ligand (TRAIL): a potential candidate for combined treatment of hematological malignancies. Current pharmaceutical design. vol 10. issue 29. 2004-12-27. PMID:15579063. |
moreover, with respect to other members of the tnf superfamily, such as cd95l and tnf-alpha, trail has generated great interest as a potential tumor-specific cancer therapeutic because as a stable soluble trimer it selectively induces apoptosis in many transformed cells but not in normal cells. |
2004-12-27 |
2023-08-12 |
Not clear |
| Paolo Monti, Federica Marchesi, Michele Reni, Alessia Mercalli, Valeria Sordi, Alessandro Zerbi, Giampaolo Balzano, Valerio Di Carlo, Paola Allavena, Lorenzo Piemont. A comprehensive in vitro characterization of pancreatic ductal carcinoma cell line biological behavior and its correlation with the structural and genetic profile. Virchows Archiv : an international journal of pathology. vol 445. issue 3. 2004-12-23. PMID:15258755. |
all the pdcl showed resistance to fas-mediated apoptosis but were significantly sensitive to the pro-apoptotic effect of inflammatory cytokines [interleukin (il)-1beta, tumor necrosis factor (tnf)alpha and interferon gamma]. |
2004-12-23 |
2023-08-12 |
Not clear |
| Jagan R Muppidi, Jürg Tschopp, Richard M Siege. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. Immunity. vol 21. issue 4. 2004-12-23. PMID:15485624. |
signaling by receptors in the tnf receptor (tnfr) superfamily mediate biological outcomes ranging from inflammation to apoptosis and other forms of programmed cell death. |
2004-12-23 |
2023-08-12 |
Not clear |
| Susan Moir, Angela Malaspina, Oxana K Pickeral, Eileen T Donoghue, Joshua Vasquez, Natalie J Miller, Surekha R Krishnan, Marie A Planta, John F Turney, J Shawn Justement, Shyamasundaran Kottilil, Mark Dybul, JoAnn M Mican, Colin Kovacs, Tae-Wook Chun, Charles E Birse, Anthony S Fauc. Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily. The Journal of experimental medicine. vol 200. issue 7. 2004-12-23. PMID:15508184. |
increased expression of the tumor necrosis factor (tnf) superfamily (tnfsf) receptor cd95 correlated with increased susceptibility to cd95-mediated apoptosis of cd21(low) b cells, which, in turn, correlated with hiv plasma viremia. |
2004-12-23 |
2023-08-12 |
human |
| H L Neville-Webbe, N A Cross, C L Eaton, R Nyambo, C A Evans, R E Coleman, I Hole. Osteoprotegerin (OPG) produced by bone marrow stromal cells protects breast cancer cells from TRAIL-induced apoptosis. Breast cancer research and treatment. vol 86. issue 3. 2004-12-22. PMID:15567943. |
the potential survival effects of opg are mediated through binding to a member of the tnf super family, tnf-related apoptosis inducing ligand (trail), preventing association between trail and its death-inducing receptors present on a number of tumour cell types. |
2004-12-22 |
2023-08-12 |
Not clear |
| Sang-Youel Park, Jae-Won Seol, You-Jin Lee, Jong-Hoo Cho, Hyung-Sub Kang, In-Shik Kim, Soo-Hyun Park, Tae-Hyoung Kim, John H Yim, Moonil Kim, Timothy R Billiar, Dai-Wu Seo. IFN-gamma enhances TRAIL-induced apoptosis through IRF-1. European journal of biochemistry. vol 271. issue 21. 2004-12-17. PMID:15511228. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf family and a potent inducer of apoptosis. |
2004-12-17 |
2023-08-12 |
Not clear |
| J M Mellado-Gil, M Aguilar-Diosdad. High glucose potentiates cytokine- and streptozotocin-induced apoptosis of rat islet cells: effect on apoptosis-related genes. The Journal of endocrinology. vol 183. issue 1. 2004-12-14. PMID:15525583. |
rat islets treated with a cytokine combination (interleukin (il)-1beta, tumor necrosis factor (tnf)-alpha and interferon (ifn)-gamma) displayed a significant increase in islet cell apoptosis when the islets were incubated in 24.4 mm glucose compared with untreated islets at the same glucose concentration (13.07 +/- 1.78% vs 6.09 +/- 0.78%; p < 0.01) or islets incubated in 5.5 mm glucose concentration and cytokines (13.07 +/- 1.78% vs 8.04 +/- 1.56%; p < 0.05). |
2004-12-14 |
2023-08-12 |
rat |
| Fang Yan, Sutha K John, Guinn Wilson, David S Jones, M Kay Washington, D Brent Pol. Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. The Journal of clinical investigation. vol 114. issue 9. 2004-12-13. PMID:15520859. |
tnf plays a pathogenic role in inflammatory bowel diseases (ibds), which are characterized by altered cytokine production and increased intestinal epithelial cell apoptosis. |
2004-12-13 |
2023-08-12 |
mouse |
| Can G Pham, Concetta Bubici, Francesca Zazzeroni, Salvatore Papa, Joy Jones, Kellean Alvarez, Shanthi Jayawardena, Enrico De Smaele, Rong Cong, Carole Beaumont, Frank M Torti, Suzy V Torti, Guido Franzos. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell. vol 119. issue 4. 2004-12-09. PMID:15537542. |
during inflammation, nf-kappab transcription factors antagonize apoptosis induced by tumor necrosis factor (tnf)alpha. |
2004-12-09 |
2023-08-12 |
Not clear |
| Léa Tourneur, Stéphanie Delluc, Vincent Lévy, Françoise Valensi, Isabelle Radford-Weiss, Ollivier Legrand, Jacques Vargaftig, Charlotte Boix, Elizabeth A Macintyre, Bruno Varet, Gilles Chiocchia, Agnès Buzy. Absence or low expression of fas-associated protein with death domain in acute myeloid leukemia cells predicts resistance to chemotherapy and poor outcome. Cancer research. vol 64. issue 21. 2004-11-30. PMID:15520222. |
in acute myeloid leukemia (aml), coexpression of death receptors and ligands of the tumor necrosis factor (tnf) receptor/tnf-alpha superfamily on leukemic cells after chemotherapy is not always accompanied by apoptosis, suggesting that the apoptotic death receptor signaling pathway is disrupted. |
2004-11-30 |
2023-08-12 |
Not clear |
| b' Lan-yi Lin, Shu-chen Li, Shu-lan L\\xc3\\xb. [Hepatitis C virus nonstructural 5A protein inhibits tumor necrosis factor alpha mediated apoptosis of HepG2 cells]. Zhonghua nei ke za zhi. vol 42. issue 6. 2004-11-23. PMID:12895322.' |
to study the suppressive effect of hcv nonstructural 5a (ns5a) protein on tumor necrosis factor alpha (tnf alpha) mediated apoptosis of hepg2 cells. |
2004-11-23 |
2023-08-12 |
Not clear |
| Soizic Daniel, Maria B Arvelo, Virendra I Patel, Christopher R Longo, Gautam Shrikhande, Tala Shukri, Jerome Mahiou, David W Sun, Christina Mottley, Shane T Grey, Christiane Ferra. A20 protects endothelial cells from TNF-, Fas-, and NK-mediated cell death by inhibiting caspase 8 activation. Blood. vol 104. issue 8. 2004-11-23. PMID:15251990. |
a20 serves a dual cytoprotective function, protecting from tumor necrosis factor (tnf)-mediated apoptosis and inhibiting inflammation via blockade of the transcription factor nuclear factor-kappab (nf-kappab). |
2004-11-23 |
2023-08-12 |
Not clear |