| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Linda C Gilbert, Janet Rubin, Mark S Nane. The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis. American journal of physiology. Endocrinology and metabolism. vol 288. issue 5. 2005-05-18. PMID:15625085. |
to evaluate the relationship between the tnf receptor mediating inhibition of ob differentiation and the role of apoptosis, marrow stromal cells (msc) were cultured from mice deficient in either or both receptors. |
2005-05-18 |
2023-08-12 |
mouse |
| Linda C Gilbert, Janet Rubin, Mark S Nane. The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis. American journal of physiology. Endocrinology and metabolism. vol 288. issue 5. 2005-05-18. PMID:15625085. |
tnf treatment that reduced differentiation by 50% did not decrease cell viability or increase apoptosis, as determined by alamar blue reduction, trypan blue exclusion, and percentage of annexin v-positive cells. |
2005-05-18 |
2023-08-12 |
mouse |
| Linda C Gilbert, Janet Rubin, Mark S Nane. The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis. American journal of physiology. Endocrinology and metabolism. vol 288. issue 5. 2005-05-18. PMID:15625085. |
these results suggest that the p55 receptor is essential, and p75 dispensable, for tnf inhibition of ob differentiation through a mechanism that does not require apoptosis. |
2005-05-18 |
2023-08-12 |
mouse |
| Mingjie Wang, Yanxin Liu, Shilian Liu, Dexian Zhen. 8-Chloro-adenosine sensitizes a human hepatoma cell line to TRAIL-induced apoptosis by caspase-dependent and -independent pathways. Oncology reports. vol 12. issue 1. 2005-05-16. PMID:15201983. |
tumor necrosis factor-related apoptosis-inducing ligand (trail), a member of the tumor necrosis factor (tnf) super-family, induces apoptosis in various cancer cells with little or no effect on normal cells. |
2005-05-16 |
2023-08-12 |
human |
| Salvatore Papa, Francesca Zazzeroni, Can G Pham, Concetta Bubici, Guido Franzos. Linking JNK signaling to NF-kappaB: a key to survival. Journal of cell science. vol 117. issue Pt 22. 2005-05-16. PMID:15483317. |
during an inflammatory response, nf-kappab activation antagonizes apoptosis induced by tumor necrosis factor (tnf)-alpha, a protective activity that involves suppression of the jun n-terminal kinase (jnk) cascade. |
2005-05-16 |
2023-08-12 |
Not clear |
| Mayank Shukla, Shuxia Yang, Carlos Milla, Angela Panoskaltsis-Mortari, Bruce R Blazar, Imad Y Hadda. Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome. American journal of physiology. Lung cellular and molecular physiology. vol 288. issue 5. 2005-05-16. PMID:15608149. |
the interaction of tnf-alpha with tnf receptor 1 (tnfr1) activates several signal transduction pathways that lead to apoptosis or nf-kappa b-dependent inflammation and immunity. |
2005-05-16 |
2023-08-12 |
mouse |
| E K Schmitz, D M Kraus, G A Bull. Tissue-specificity of apoptosis in hepatoma-derived cell lines. Apoptosis : an international journal on programmed cell death. vol 9. issue 3. 2005-05-13. PMID:15258469. |
here, we show that dedifferentiated hepatoma cells undergo apoptosis in response to multiple compounds, including sorbitol (to induce hyperosmotic shock), tnf alpha and the microtubule damaging agent vinblastin. |
2005-05-13 |
2023-08-12 |
Not clear |
| Mani Alikhani, Zoubin Alikhani, Dana T Grave. FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. The Journal of biological chemistry. vol 280. issue 13. 2005-05-13. PMID:15632117. |
these results indicate that tnf induces activation of the foxo1 transcription factor, which acts as a master switch to control apoptosis. |
2005-05-13 |
2023-08-12 |
human |
| Elad Katz, Mohamed H Lareef, John C Rassa, Shannon M Grande, Leslie B King, Jose Russo, Susan R Ross, John G Monro. MMTV Env encodes an ITAM responsible for transformation of mammary epithelial cells in three-dimensional culture. The Journal of experimental medicine. vol 201. issue 3. 2005-05-12. PMID:15684322. |
env-expressing cells bear hallmarks of cell transformation such as sensitivity to apoptosis induced by tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) or tnfalpha, as well as down-regulation of e-cadherin and keratin-18. |
2005-05-12 |
2023-08-12 |
mouse |
| Ximing Tang, Weiguo Wu, Shi-Yong Sun, Ignacio I Wistuba, Waun Ki Hong, Li Ma. Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells. Molecular cancer research : MCR. vol 2. issue 12. 2005-05-05. PMID:15634757. |
death-associated protein (dap) kinase plays an important role in ifn-gamma, tumor necrosis factor (tnf)-alpha, or fas-ligand induced apoptosis. |
2005-05-05 |
2023-08-12 |
human |
| Ximing Tang, Weiguo Wu, Shi-Yong Sun, Ignacio I Wistuba, Waun Ki Hong, Li Ma. Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells. Molecular cancer research : MCR. vol 2. issue 12. 2005-05-05. PMID:15634757. |
tnf-related apoptosis-inducing ligand (trail) is a member of the tnf ligand family and can induce caspase-dependent apoptosis in cancer cells while sparing most of the normal cells. |
2005-05-05 |
2023-08-12 |
human |
| Andrew S Cowburn, Jessica F White, John Deighton, Sarah R Walmsley, Edwin R Chilver. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood. vol 105. issue 7. 2005-05-03. PMID:15572588. |
z-vad-fmk augmentation of tnf alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. |
2005-05-03 |
2023-08-12 |
Not clear |
| Andrew S Cowburn, Jessica F White, John Deighton, Sarah R Walmsley, Edwin R Chilver. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood. vol 105. issue 7. 2005-05-03. PMID:15572588. |
while confirming that z-vad-fmk (> 100 microm) enhances tnf alpha-induced neutrophil apoptosis, lower concentrations (1-30 microm) completely blocked tnf alpha-stimulated apoptosis. |
2005-05-03 |
2023-08-12 |
Not clear |
| Andrew S Cowburn, Jessica F White, John Deighton, Sarah R Walmsley, Edwin R Chilver. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood. vol 105. issue 7. 2005-05-03. PMID:15572588. |
boc-d-fmk, a similar broad-spectrum caspase inhibitor, and z-ietd-fmk, a selective caspase-8 inhibitor, caused a concentration-dependent inhibition of only tnf alpha-stimulated apoptosis. |
2005-05-03 |
2023-08-12 |
Not clear |
| Andrew S Cowburn, Jessica F White, John Deighton, Sarah R Walmsley, Edwin R Chilver. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood. vol 105. issue 7. 2005-05-03. PMID:15572588. |
moreover, the caspase-9 inhibitor, ac-lehd-cmk, had no effect on tnf alpha-induced apoptosis, and z-vad-fmk and boc-d-fmk inhibited tnf alpha-stimulated reactive oxygen species (ros) generation. |
2005-05-03 |
2023-08-12 |
Not clear |
| Andrew S Cowburn, Jessica F White, John Deighton, Sarah R Walmsley, Edwin R Chilver. z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species. Blood. vol 105. issue 7. 2005-05-03. PMID:15572588. |
these data suggest that tnf alpha-induced apoptosis in neutrophils is fully caspase dependent and uses a mitochondrial-independent pathway and that the proapoptotic effects of z-vad-fmk are compound specific and ros independent. |
2005-05-03 |
2023-08-12 |
Not clear |
| A C Bharti, B B Aggarwa. Ranking the role of RANK ligand in apoptosis. Apoptosis : an international journal on programmed cell death. vol 9. issue 6. 2005-04-28. PMID:15505411. |
many members of tumor necrosis factor (tnf) superfamily are characterized by their ability to induce apoptosis once they bind in a homotrimeric manner to their cognate receptors. |
2005-04-28 |
2023-08-12 |
Not clear |
| Eiko Takada, Kuniaki Shimo, Kikumi Hata, Maira Abiake, Yasuo Mukai, Masami Moriyama, Lynn Heasley, Junichiro Mizuguch. Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells. Experimental cell research. vol 304. issue 2. 2005-04-28. PMID:15748896. |
in the present study, we demonstrate that ifn-beta induced apoptosis and the loss of mitochondrial membrane potential (delta psi m) in the murine ch31 b lymphoma cell line, and this was accompanied by the up-regulation of cd95, but not cd95-ligand (cd95-l), tumor necrosis factor (tnf), or tnf-related apoptosis-inducing ligand (trail). |
2005-04-28 |
2023-08-12 |
Not clear |
| Chun-Ling Sun, Chuck C-K Cha. Cross-resistance to death ligand-induced apoptosis in cisplatin-selected HeLa cells associated with overexpression of DDB2 and subsequent induction of cFLIP. Molecular pharmacology. vol 67. issue 4. 2005-04-20. PMID:15644494. |
these findings reveal that ddb2 regulates tnf signaling-mediated apoptosis via cflip and contributes to acquired cross-resistance. |
2005-04-20 |
2023-08-12 |
Not clear |
| Ingo H Engels, Gudrun Totzke, Ute Fischer, Klaus Schulze-Osthoff, Reiner U Jänick. Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner. Molecular and cellular biology. vol 25. issue 7. 2005-04-19. PMID:15767684. |
here we show that expression of caspase-10 sensitizes mcf-7 breast carcinoma cells to trail- but not tumor necrosis factor (tnf)-induced apoptosis. |
2005-04-19 |
2023-08-12 |
Not clear |