| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui-Yu Qin, Pratibha Chaturvedi, Bhagirath Sing. In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha. International immunology. vol 16. issue 12. 2005-04-18. PMID:15492021. |
bcg immunization sequentially induced the production of tnf-alpha, ifn-gamma and il-4 by splenocytes, increased the expression of fas(high) (apo-1/cd95), fas ligand (fasl, cd95l) and tnf receptor (tnfr) on t cells leading to t cell apoptosis. |
2005-04-18 |
2023-08-12 |
mouse |
| Hui-Yu Qin, Pratibha Chaturvedi, Bhagirath Sing. In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha. International immunology. vol 16. issue 12. 2005-04-18. PMID:15492021. |
we show that fas and tnf are two pathways in bcg-induced apoptosis of diabetogenic t cells, since in vitro blocking fasl or tnfr1 with antibody reduced t cell apoptosis and increased t cell proliferative response. |
2005-04-18 |
2023-08-12 |
mouse |
| Hui-Yu Qin, Pratibha Chaturvedi, Bhagirath Sing. In vivo apoptosis of diabetogenic T cells in NOD mice by IFN-gamma/TNF-alpha. International immunology. vol 16. issue 12. 2005-04-18. PMID:15492021. |
our results suggest that bcg down-regulates destructive autoimmunity by tnf-alpha/ifn-gamma-induced apoptosis of diabetogenic t cells through both fas and tnf pathways. |
2005-04-18 |
2023-08-12 |
mouse |
| Ying-Hsin Chang, Yee Chao, Shie-Liang Hsieh, Wan-Wan Li. Mechanism of LIGHT/interferon-gamma-induced cell death in HT-29 cells. Journal of cellular biochemistry. vol 93. issue 6. 2005-04-14. PMID:15486969. |
light is a member of tumor necrosis factor (tnf) superfamily, and previous studies have indicated that in the presence of interferon-gamma (ifn-gamma), light through ltbetar signaling can induce cell death with features unlike classic apoptosis. |
2005-04-14 |
2023-08-12 |
Not clear |
| Koichi Setsuta, Yoshihiko Seino, Takeshi Ogawa, Toshiaki Ohtsuka, Kohji Seimiya, Teruo Takan. Ongoing myocardial damage in chronic heart failure is related to activated tumor necrosis factor and Fas/Fas ligand system. Circulation journal : official journal of the Japanese Circulation Society. vol 68. issue 8. 2005-04-12. PMID:15277733. |
cardiomyocyte necrosis and/or apoptosis via activated tumor necrosis factor (tnf) and the fas/fas ligand (fasl) system may be related to the development of omd. |
2005-04-12 |
2023-08-12 |
Not clear |
| O Bajenova, B Tang, R Pearse, R Feinman, B H Childs, J Michael. RIP kinase is involved in arsenic-induced apoptosis in multiple myeloma cells. Apoptosis : an international journal on programmed cell death. vol 9. issue 5. 2005-04-12. PMID:15314284. |
rip is a key downstream protein in fasl/ tnf alpha /trail induced apoptosis and a major antiapoptotic adaptor of pathways through nf-kappa b and jnk. |
2005-04-12 |
2023-08-12 |
human |
| Melissa J Peart, Gordon K Smyth, Ryan K van Laar, David D Bowtell, Victoria M Richon, Paul A Marks, Andrew J Holloway, Ricky W Johnston. Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 10. 2005-04-07. PMID:15738394. |
multiple genes within the myc, type beta tgf, cyclin/cyclin-dependent kinase, tnf, bcl-2, and caspase pathways were regulated in a manner that favored induction of apoptosis and decreased cellular proliferation. |
2005-04-07 |
2023-08-12 |
Not clear |
| Dongmei Lu, Jie Huang, Alakananda Bas. Deregulation of PKB influences antiapoptotic signaling by PKC in breast cancer cells. International journal of oncology. vol 25. issue 3. 2005-04-04. PMID:15289868. |
we have previously shown that novel protein kinase c (npkc) isozymes, such as npkcepsilon, negatively regulate tnf-induced apoptosis in breast cancer cells although the level on npkcs did not correlate with cellular sensitivity to tnf. |
2005-04-04 |
2023-08-12 |
Not clear |
| Tadashi Narita, Tadahiro Nishimura, Kazuyuki Yoshizaki, Tadayoshi Taniyam. CIN85 associates with TNF receptor 1 via Src and modulates TNF-alpha-induced apoptosis. Experimental cell research. vol 304. issue 1. 2005-04-04. PMID:15707590. |
cin85 associates with tnf receptor 1 via src and modulates tnf-alpha-induced apoptosis. |
2005-04-04 |
2023-08-12 |
human |
| László Leindler, Eva Morschl, Ferenc László, Yvette Mándi, Tamás Takács, Katalin Jármai, Gyula Farka. Importance of cytokines, nitric oxide, and apoptosis in the pathological process of necrotizing pancreatitis in rats. Pancreas. vol 29. issue 2. 2005-03-29. PMID:15257108. |
the aim of our study was to determine the production of cytokines, tumor necrosis factor (tnf) and interleukin-6 (il-6), the activation of the inducible nitric oxide synthase (inos), and the development of apoptosis during this pathologic process. |
2005-03-29 |
2023-08-12 |
rat |
| Katya Chobotova, Natalia Karpovich, Janet Carver, Sanjiv Manek, William J Gullick, David H Barlow, Helen J Mardo. Heparin-binding epidermal growth factor and its receptors mediate decidualization and potentiate survival of human endometrial stromal cells. The Journal of clinical endocrinology and metabolism. vol 90. issue 2. 2005-03-24. PMID:15562026. |
our data suggest that hb-egf has a function in endometrial maturation in mediating decidualization and attenuating tnf alpha- and tgf beta-induced apoptosis of endometrial stromal cells. |
2005-03-24 |
2023-08-12 |
human |
| Zhongbiao Wang, Pulipaka J Rao, Manuel R Castresana, Walter H Newma. TNF-alpha induces proliferation or apoptosis in human saphenous vein smooth muscle cells depending on phenotype. American journal of physiology. Heart and circulatory physiology. vol 288. issue 1. 2005-03-22. PMID:15358608. |
tumor necrosis factor (tnf)-alpha is implicated in development of restenotic and atherosclerotic vascular lesions, which are pathological processes involving both proliferation and apoptosis of vascular smooth muscle cells (vsmcs). |
2005-03-22 |
2023-08-12 |
human |
| Zhongbiao Wang, Pulipaka J Rao, Manuel R Castresana, Walter H Newma. TNF-alpha induces proliferation or apoptosis in human saphenous vein smooth muscle cells depending on phenotype. American journal of physiology. Heart and circulatory physiology. vol 288. issue 1. 2005-03-22. PMID:15358608. |
tnf did not induce apoptosis in sp-smcs as determined by nuclear staining and cellular dna electrophoresis. |
2005-03-22 |
2023-08-12 |
human |
| Zhongbiao Wang, Pulipaka J Rao, Manuel R Castresana, Walter H Newma. TNF-alpha induces proliferation or apoptosis in human saphenous vein smooth muscle cells depending on phenotype. American journal of physiology. Heart and circulatory physiology. vol 288. issue 1. 2005-03-22. PMID:15358608. |
the data presented here demonstrate for the first time that tnf either promotes growth or induces apoptosis in human vsmcs depending on phenotype. |
2005-03-22 |
2023-08-12 |
human |
| Fiona C Kimberley, Gavin R Screato. Following a TRAIL: update on a ligand and its five receptors. Cell research. vol 14. issue 5. 2005-03-22. PMID:15538968. |
identification of tumour necrosis factor apoptosis inducing ligand (trail), a tnf family ligand, sparked a torrent of research, following an initial observation that it could kill tumour cells, but spare normal cells. |
2005-03-22 |
2023-08-12 |
Not clear |
| A M Mueller, X Pedré, I Kleiter, M Hornberg, A Steinbrecher, G Giegeric. Targeting fibroblast growth factor-inducible-14 signaling protects from chronic relapsing experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 159. issue 1-2. 2005-03-18. PMID:15652403. |
the tnf-related weak inducer of apoptosis (tweak) is a tnf family member mediating proinflammatory effects by its receptor fibroblast growth factor-inducible-14 (fn14). |
2005-03-18 |
2023-08-12 |
mouse |
| Mary Philip, Donald A Rowley, Hans Schreibe. Inflammation as a tumor promoter in cancer induction. Seminars in cancer biology. vol 14. issue 6. 2005-03-16. PMID:15489136. |
tnf, a key pro-inflammatory cytokine when binding to tnf receptor 1 (tnfr1), may cause survival or apoptosis, dependent on biochemical modifications that determine the type of complex formed; one complex causes nfkappab activation and gives a cell survival signal (pro-oncogenic), while the other (modified) complex recruits caspases and causes apoptosis (anti-oncogenic). |
2005-03-16 |
2023-08-12 |
Not clear |
| Yoshinori Kobayashi, Masaaki Mori, Takuya Naruto, Naoki Kobayashi, Toshiyuki Sugai, Tomoyuki Imagawa, Shumpei Yokot. Dynamic movement of cytochrome c from mitochondria into cytosol and peripheral circulation in massive hepatic cell injury. Pediatrics international : official journal of the Japan Pediatric Society. vol 46. issue 6. 2005-03-10. PMID:15660868. |
in the process of apoptosis, it is known that the transition of cytochrome c from mitochondria into the cytosol occurs, and tumor necrosis factor (tnf)-alpha is one of the molecules responsible for this event. |
2005-03-10 |
2023-08-12 |
Not clear |
| Miyuki Harada, Yutaka Osuga, Tetsuya Hirata, Yasushi Hirota, Kaori Koga, Osamu Yoshino, Chieko Morimoto, Toshihiro Fujiwara, Mikio Momoeda, Tetsu Yano, Osamu Tsutsumi, Yuji Taketan. Concentration of osteoprotegerin (OPG) in peritoneal fluid is increased in women with endometriosis. Human reproduction (Oxford, England). vol 19. issue 10. 2005-03-08. PMID:15242994. |
osteoprotegerin (opg) is a survival factor that exerts its effect by binding to tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), thus preventing trail from binding to the apoptosis receptors dr4 and dr5. |
2005-03-08 |
2023-08-12 |
Not clear |
| Hironaga Kamiyama, Kunikazu Kurosaki, Masanori Kurimoto, Toyomasa Katagiri, Yusuke Nakamura, Masahiko Kurokawa, Hitoshi Sato, Shunro Endo, Kimiyasu Shirak. Herpes simplex virus-induced, death receptor-dependent apoptosis and regression of transplanted human cancers. Cancer science. vol 95. issue 12. 2005-03-08. PMID:15596049. |
the infected cells underwent histochemically confirmed apoptosis without lymphocyte infiltration after expressing cd30, cd30 ligand (cd30l), tumor necrosis factor (tnf)-alpha, tnf receptor 1 (tnf-r1), fas, and fas ligand (fas-l) with activation of caspases 3 and 8. |
2005-03-08 |
2023-08-12 |
mouse |