| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Costa, N K Bell, T J Stabel, W L Fodo. Use of porcine tumor necrosis factor receptor 1-Ig fusion protein to prolong xenograft survival. Xenotransplantation. vol 11. issue 6. 2005-03-04. PMID:15479458. |
tumor necrosis factor (tnf) is believed to play a role in this process by promoting cell activation, apoptosis and the recruitment of inflammatory cells. |
2005-03-04 |
2023-08-12 |
human |
| Werner Stenzel, Sabine Soltek, Hrvoje Miletic, Manuel Marcel Hermann, Heinrich Körner, Jonathon D Sedgwick, Dirk Schlüter, Martina Decker. An essential role for tumor necrosis factor in the formation of experimental murine Staphylococcus aureus-induced brain abscess and clearance. Journal of neuropathology and experimental neurology. vol 64. issue 1. 2005-03-03. PMID:15715082. |
infiltrates was delayed in tnf(0/0)mice correlating with reduced apoptosis of inflammatory leukocytes and formation of a fibrous abscess capsule. |
2005-03-03 |
2023-08-12 |
mouse |
| M Gerlic, J Horowitz, S Horowit. Mycoplasma fermentans inhibits tumor necrosis factor alpha-induced apoptosis in the human myelomonocytic U937 cell line. Cell death and differentiation. vol 11. issue 11. 2005-03-02. PMID:15286682. |
we investigated whether m. fermentans has a pathogenic potential by affecting tumor necrosis factor (tnf)alpha-induced apoptosis in the human myelomonocytic u937 cell line. |
2005-03-02 |
2023-08-12 |
human |
| H Hasegawa, Y Yamada, H Harasawa, T Tsuji, K Murata, K Sugahara, K Tsuruda, S Ikeda, Y Imaizumi, M Tomonaga, M Masuda, N Takasu, S Kamihir. Sensitivity of adult T-cell leukaemia lymphoma cells to tumour necrosis factor-related apoptosis-inducing ligand. British journal of haematology. vol 128. issue 2. 2005-03-02. PMID:15638862. |
tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces apoptosis in many transformed cells, but not in normal cells, and hence trail has recently emerged as a novel anti-cancer agent. |
2005-03-02 |
2023-08-12 |
human |
| Konstantin G Lyamzaev, Denis S Izyumov, Armine V Avetisyan, Fuyu Yang, Olga Yu Pletjushkina, Boris V Chernya. Inhibition of mitochondrial bioenergetics: the effects on structure of mitochondria in the cell and on apoptosis. Acta biochimica Polonica. vol 51. issue 2. 2005-02-25. PMID:15218549. |
the inhibitors of respiration (piericidin, antimycin, myxothiazol), the f(1)-component of atp synthase (aurovertin) and uncouplers (dnp, fccp) did not affect viability of hela cells, apoptosis induced by tnf or staurosporin and the anti-apoptotic action of bcl-2. |
2005-02-25 |
2023-08-12 |
Not clear |
| Tai-Guang Jin, Alexei Kurakin, Nordine Benhaga, Karon Abe, Mehrdad Mohseni, Ferry Sandra, Keli Song, Brian K Kay, Roya Khosravi-Fa. Fas-associated protein with death domain (FADD)-independent recruitment of c-FLIPL to death receptor 5. The Journal of biological chemistry. vol 279. issue 53. 2005-02-25. PMID:15485835. |
here we show a novel mechanism by which flice-like inhibitory protein (c-flip) regulates apoptosis induced by tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and one of its receptors, dr5. |
2005-02-25 |
2023-08-12 |
Not clear |
| Francisco J Dieguez-Acuña, William W Polk, Maureen E Ellis, P Lynne Simmonds, John V Kushleika, James S Wood. Nuclear factor kappaB activity determines the sensitivity of kidney epithelial cells to apoptosis: implications for mercury-induced renal failure. Toxicological sciences : an official journal of the Society of Toxicology. vol 82. issue 1. 2005-02-22. PMID:15282405. |
however, when tnf was given following hg(2+) pretreatment (0.5 to 5 microm for 30 min), the proportion of cells undergoing apoptosis increased by 2- to 6-fold over that seen in untreated controls. |
2005-02-22 |
2023-08-12 |
rat |
| Francisco J Dieguez-Acuña, William W Polk, Maureen E Ellis, P Lynne Simmonds, John V Kushleika, James S Wood. Nuclear factor kappaB activity determines the sensitivity of kidney epithelial cells to apoptosis: implications for mercury-induced renal failure. Toxicological sciences : an official journal of the Society of Toxicology. vol 82. issue 1. 2005-02-22. PMID:15282405. |
kidney cells pretreated with specific nf-kappab inhibitors (bay11-7082 or sn50) prior to tnf also showed a significant increase in apoptosis. |
2005-02-22 |
2023-08-12 |
rat |
| Anca Irinel Catrina, Christina Trollmo, Erik af Klint, Marianne Engstrom, Jon Lampa, Ylva Hermansson, Lars Klareskog, Ann Kristin Ulfgre. Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: extended report. Arthritis and rheumatism. vol 52. issue 1. 2005-02-15. PMID:15641091. |
since anti-tnf therapy induces a decrease in synovial cellularity, this study focused on the modulation of ra synovial apoptosis following treatment with either soluble tnf receptor (etanercept) or tnf chimeric monoclonal antibody (infliximab). |
2005-02-15 |
2023-08-12 |
Not clear |
| M Sawada, T Kiyono, S Nakashima, J Shinoda, T Naganawa, S Hara, T Iwama, N Saka. Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways. Cell death and differentiation. vol 11. issue 9. 2005-02-14. PMID:15131591. |
the present study was designed to examine the roles of p53, reactive oxygen species (ros), and ceramide, and to determine their mutual relationships during tumor necrosis factor (tnf)-alpha-induced apoptosis of human glioma cells. |
2005-02-14 |
2023-08-12 |
human |
| Maowen Hu, Xinchun Lin, Qiaoting Du, Edmund J Miller, Ping Wang, H Hank Simm. Regulation of polymorphonuclear leukocyte apoptosis: role of lung endothelium-epithelium bilayer transmigration. American journal of physiology. Lung cellular and molecular physiology. vol 288. issue 2. 2005-02-11. PMID:15475382. |
furthermore, the reduced apoptosis was correlated with downregulation of fas ligand and tnf receptor 1 expression. |
2005-02-11 |
2023-08-12 |
human |
| Claudine Tardy, Hélène Autefage, Virgine Garcia, Thierry Levade, Nathalie Andrieu-Abadi. Mannose 6-phosphorylated proteins are required for tumor necrosis factor-induced apoptosis: defective response in I-cell disease fibroblasts. The Journal of biological chemistry. vol 279. issue 51. 2005-02-04. PMID:15452110. |
this study investigated the role of lysosomal mannose 6-phosphorylated proteins in tumor necrosis factor (tnf)-induced apoptosis. |
2005-02-04 |
2023-08-12 |
mouse |
| Hong Xiang, Cindy B Nguyen, Sean K Kelley, Noel Dybdal, Enrique Escandó. Tissue distribution, stability, and pharmacokinetics of Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in human colon carcinoma COLO205 tumor-bearing nude mice. Drug metabolism and disposition: the biological fate of chemicals. vol 32. issue 11. 2005-02-01. PMID:15282212. |
apo2l/trail [apo2 ligand/tumor necrosis factor (tnf)-related apoptosis-inducing ligand], a member of the tnf cytokine superfamily, induces cell death by apoptosis in a number of human cancer cells and is a potential agent for cancer therapy. |
2005-02-01 |
2023-08-12 |
mouse |
| Lance R Thomas, Ronald L Johnson, John C Reed, Andrew Thorbur. The C-terminal tails of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas receptors have opposing functions in Fas-associated death domain (FADD) recruitment and can regulate agonist-specific mechanisms of receptor activation. The Journal of biological chemistry. vol 279. issue 50. 2005-02-01. PMID:15452120. |
members of the tumor necrosis factor (tnf) superfamily of receptors such as fas/cd95 and the tnf-related apoptosis-inducing ligand (trail) receptors dr4 and dr5 induce apoptosis by recruiting adaptor molecules and caspases. |
2005-02-01 |
2023-08-12 |
Not clear |
| Bruce E Sand. Why do anti-tumor necrosis factor antibodies work in Crohn's disease? Reviews in gastroenterological disorders. vol 4 Suppl 3. 2005-02-01. PMID:15580148. |
transmembrane binding of tnf effects apoptosis of t cells, thereby alleviating a fundamental defect in crohn's disease in the regulation of t cell populations. |
2005-02-01 |
2023-08-12 |
Not clear |
| Wen-Xing Ding, Xiao-Ming Yi. Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury. Journal of cellular and molecular medicine. vol 8. issue 4. 2005-01-31. PMID:15601573. |
tumor necrosis factor (tnf)-alpha-induced hepatocyte apoptosis is implicated in a wide range of liver diseases including viral hepatitis, alcoholic hepatitis, ischemia/reperfusion liver injury, and fulminant hepatic failure. |
2005-01-31 |
2023-08-12 |
Not clear |
| Mihaela Ringheanu, Fredric Daum, James Markowitz, Jeremiah Levine, Seymour Katz, Xingyu Lin, Jack Silve. Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease. Inflammatory bowel diseases. vol 10. issue 6. 2005-01-31. PMID:15626899. |
infliximab, an anti-tumor necrosis factor (tnf) monoclonal antibody, might exert some of its long-term therapeutic effects in crohn's disease (cd) by interacting directly with cells of the immune system such as monocytes and t lymphocytes via membrane tnf and by inducing apoptosis. |
2005-01-31 |
2023-08-12 |
Not clear |
| Chunhai Hao, Jin H Song, Belinda Hsi, Jamie Lewis, Doyoun K Song, Kenneth C Petruk, David L J Tyrrell, Norman M Knetema. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer research. vol 64. issue 23. 2005-01-27. PMID:15574753. |
tumor necrosis factor (tnf) family ligand tnf-alpha and fas ligand (fasl) can trigger apoptosis in solid tumors, but their clinical usage has been limited by hepatotoxicity. |
2005-01-27 |
2023-08-12 |
mouse |
| Richard M Siegel, Jagan R Muppidi, Malabika Sarker, Adrian Lobito, Melinda Jen, David Martin, Stephen E Straus, Michael J Lenard. SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor-induced apoptosis at the plasma membrane. The Journal of cell biology. vol 167. issue 4. 2005-01-19. PMID:15557123. |
fas (cd95, apo-1, tnfrsf6) is a tnf receptor superfamily member that directly triggers apoptosis and contributes to the maintenance of lymphocyte homeostasis and prevention of autoimmunity. |
2005-01-19 |
2023-08-12 |
Not clear |
| Baoli Hu, Huabin Zhu, Songbo Qiu, Yue Su, Weifang Ling, Wei Xiao, Yipeng Q. Enhanced TRAIL sensitivity by E1A expression in human cancer and normal cell lines: inhibition by adenovirus E1B19K and E3 proteins. Biochemical and biophysical research communications. vol 325. issue 4. 2005-01-18. PMID:15555548. |
tnf-related apoptosis-inducing ligand (trail) is a member of the tnf superfamily of cytokines that induces apoptosis in a variety of cancer cells, but not in normal cells. |
2005-01-18 |
2023-08-12 |
human |