| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arne Lange, Lutz Thon, Sabine Mathieu, Dieter Ada. The apoptosis inhibitory domain of FE65-like protein 1 regulates both apoptotic and caspase-independent programmed cell death mediated by tumor necrosis factor. Biochemical and biophysical research communications. vol 335. issue 2. 2005-10-14. PMID:16083851. |
here, we demonstrate that stable transfection of a cdna encompassing the c-terminal apoptosis inhibitory domain (aid) of fe65-like protein 1 into mouse l929 fibrosarcoma cells protects from caspase-independent as well as from apoptotic pcd induced by tnf. |
2005-10-14 |
2023-08-12 |
mouse |
| Yuhang Zhang, Stephen Rosenberg, Hanming Wang, Hongxia Z Imtiyaz, Ying-Ju Hou, Jianke Zhan. Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis. Journal of immunology (Baltimore, Md. : 1950). vol 175. issue 5. 2005-10-14. PMID:16116191. |
sorted gfp-negative thymocytes and peripheral t cells contained undetectable levels of fadd and were resistant to apoptosis induced by fas, tnf, and tcr restimulation. |
2005-10-14 |
2023-08-12 |
mouse |
| Masami Ishid. Overexpression of Bcl-2 inhibits nuclear localization of annexin I during tumor necrosis factor-alpha-mediated apoptosis in porcine renal LLC-PK1 cells. Regulatory peptides. vol 124. issue 1-3. 2005-10-06. PMID:15544840. |
the addition of tumor necrosis factor (tnf)-alpha into the cultured porcine kidney llc-pk1 cells caused apoptosis concomitantly with caspase-3 activation and the inductions of an endogenous bcl-2 protein. |
2005-10-06 |
2023-08-12 |
Not clear |
| Roberto Stasi, Sergio Amadori, Adrian C Newland, Drew Prova. Infliximab chimeric antitumor necrosis factor-a monoclonal antibody as potential treatment for myelodysplastic syndromes. Leukemia & lymphoma. vol 46. issue 4. 2005-10-05. PMID:16019478. |
the identification of tnf-a as a regulator of apoptosis and the increased susceptibility of mds cells to this cytokine provided the basis for several clinical trials of tnf inhibitors. |
2005-10-05 |
2023-08-12 |
human |
| Zuzana Strakova, Patricia Mavrogianis, Xuemei Meng, Julie M Hastings, Kevin S Jackson, Paula Cameo, Allison Brudney, Oluwatoyin Knight, Asgerally T Fazleaba. In vivo infusion of interleukin-1beta and chorionic gonadotropin induces endometrial changes that mimic early pregnancy events in the baboon. Endocrinology. vol 146. issue 9. 2005-09-29. PMID:15932926. |
protein arrays of uterine flushings showed significant suppression of death receptors, fas and tnf receptor 1, in the hcg- with or without il-1beta-treated groups, suggesting an inhibition of apoptosis. |
2005-09-29 |
2023-08-12 |
human |
| Axel Thiefes, Sabine Wolter, J Frederic Mushinski, Elke Hoffmann, Oliver Dittrich-Breiholz, Nadine Graue, Anneke Dörrie, Heike Schneider, Dagmar Wirth, Bruno Luckow, Klaus Resch, Michael Krach. Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes. The Journal of biological chemistry. vol 280. issue 30. 2005-09-22. PMID:15837794. |
expression of this protein inhibited tumor necrosis factor (tnf)-induced activation of nfkappab, jnk, and p38 mapk and sensitized the cells to tnf-induced apoptosis. |
2005-09-22 |
2023-08-12 |
Not clear |
| John Verbsky, Philip W Majeru. Increased levels of inositol hexakisphosphate (InsP6) protect HEK293 cells from tumor necrosis factor (alpha)- and Fas-induced apoptosis. The Journal of biological chemistry. vol 280. issue 32. 2005-09-22. PMID:15967797. |
the overexpression of inositol 1,3,4-trisphosphate 5/6-kinase has recently been shown to protect hek293 cells from tumor necrosis factor alpha (tnf(alpha))-induced apoptosis. |
2005-09-22 |
2023-08-12 |
Not clear |
| Jae-Won Seol, You-Jin Lee, Hyung-sub Kang, In-shik Kim, Nam-soo Kim, Yong-Geun Kwak, Tae-Hyung Kim, Dai-Wu Seol, Sang-Youel Par. Wortmannin elevates tumor necrosis factor-related apoptosis-inducing ligand sensitivity in LNCaP cells through down-regulation of IAP-2 protein. Experimental oncology. vol 27. issue 2. 2005-09-20. PMID:15995629. |
tnf-related apoptosis-inducing ligand (trail), which is a member of the tumor necrosis factor (tnf) family, has been shown to effectively induce tumor apoptosis without any detectable cytotoxic side effects. |
2005-09-20 |
2023-08-12 |
Not clear |
| Lina Y Dimberg, Anna I Dimberg, Karolina Ivarsson, Thomas Strömberg, Anders Osterborg, Kenneth Nilsson, Fredrik Oberg, Helena Jernberg Wiklun. Ectopic and IFN-induced expression of Fas overcomes resistance to Fas-mediated apoptosis in multiple myeloma cells. Blood. vol 106. issue 4. 2005-09-19. PMID:15860671. |
in a wide screening of apoptosis-related genes, apo2l/trail (tumor necrosis factor [tnf]-related apoptosis inducing ligand) and fas were identified as ifn targets. |
2005-09-19 |
2023-08-12 |
Not clear |
| Tanya N Mayadas, Xavier Culler. Neutrophil beta2 integrins: moderators of life or death decisions. Trends in immunology. vol 26. issue 7. 2005-09-15. PMID:15922663. |
however, in the presence of pro-apoptotic signals, such as tumor necrosis factor (tnf), mac-1 engagement accelerates apoptosis. |
2005-09-15 |
2023-08-12 |
Not clear |
| Bart Depuydt, Geert van Loo, Peter Vandenabeele, Wim Declerc. Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors. Journal of cell science. vol 118. issue Pt 3. 2005-09-14. PMID:15657078. |
induction of apoptosis by tnf receptor 2 in a t-cell hybridoma is fadd dependent and blocked by caspase-8 inhibitors. |
2005-09-14 |
2023-08-12 |
human |
| Bart Depuydt, Geert van Loo, Peter Vandenabeele, Wim Declerc. Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors. Journal of cell science. vol 118. issue Pt 3. 2005-09-14. PMID:15657078. |
tnfr2-induced apoptosis is independent of endogenous tnf or other death-inducing ligand production and subsequent activation of tnfr1 or other death receptors. |
2005-09-14 |
2023-08-12 |
human |
| Hun Sik Kim, Inik Chang, Ja Young Kim, Kyung-Hee Choi, Myung-Shik Le. Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis. Cancer research. vol 65. issue 14. 2005-09-14. PMID:16024612. |
however, signal transduction in trail-mediated apoptosis is not clearly understood compared with other tnf family members. |
2005-09-14 |
2023-08-12 |
Not clear |
| Ramya Sundararajan, Guanghua Chen, Chandreyee Mukherjee, Eileen Whit. Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling. Oncogene. vol 24. issue 31. 2005-09-01. PMID:15824730. |
we identified the generation of amino-terminally truncated versions of dbc-1 during tumor necrosis factor (tnf)-alpha-mediated apoptosis. |
2005-09-01 |
2023-08-12 |
human |
| Sang-Yun Lee, Rama P Cherla, Isa Caliskan, Vernon L Tes. Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase-8-dependent, tumor necrosis factor receptor-independent mechanism. Infection and immunity. vol 73. issue 8. 2005-08-26. PMID:16041028. |
here, we show that stx1 induces apoptosis in the undifferentiated myelogenous leukemia cell line thp-1 in the absence of tumor necrosis factor alpha (tnf-alpha) or death receptor (tnf receptor or fas) expression. |
2005-08-26 |
2023-08-12 |
human |
| Richard E Kast, Erick L Altschule. Anti-apoptosis function of TNF-alpha in chronic lymphocytic leukemia: lessons from Crohn's disease and the therapeutic potential of bupropion to lower TNF-alpha. Archivum immunologiae et therapiae experimentalis. vol 53. issue 2. 2005-08-24. PMID:15928583. |
that failure is partly due to increased signaling by tumor necrosis factor (tnf)-alpha, and their respective pathologies directly follow from this apoptosis failure. |
2005-08-24 |
2023-08-12 |
Not clear |
| Andy Wullaert, Ben Wielockx, Sofie Van Huffel, Veerle Bogaert, Bart De Geest, Peggy Papeleu, Peter Schotte, Karim El Bakkouri, Karen Heyninck, Claude Libert, Rudi Beyaer. Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality. Hepatology (Baltimore, Md.). vol 42. issue 2. 2005-08-18. PMID:16025521. |
indeed, abin-1 was found to prevent not only nf-kappab activation, but also apoptosis of cultured hepatocytes in response to tnf, explaining its protective effect against tnf-induced liver failure. |
2005-08-18 |
2023-08-12 |
mouse |
| Haruyo Ichikawa, Yasunari Takada, Akira Murakami, Bharat B Aggarwa. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 11. 2005-08-08. PMID:15905586. |
aca also enhanced the apoptosis induced by tnf and chemotherapeutic agents and suppressed invasion. |
2005-08-08 |
2023-08-12 |
Not clear |
| Martin Handfield, Jeffrey J Mans, Gaolin Zheng, M Cecilia Lopez, Song Mao, Ann Progulske-Fox, Giri Narasimhan, Henry V Baker, Richard J Lamon. Distinct transcriptional profiles characterize oral epithelium-microbiota interactions. Cellular microbiology. vol 7. issue 6. 2005-08-02. PMID:15888084. |
furthermore, with a. actinomycetemcomitans, the induction of apoptosis did not appear to be fas- or tnf(alpha)-mediated. |
2005-08-02 |
2023-08-12 |
human |
| A Zambon Bertoja, M L Zenclussen, I Wollenberg, S Paeschke, A Sollwedel, K Gerlof, C Woiciechowsky, H-D Volk, A C Zenclusse. Upregulation of Bcl-2 at the foetal-maternal interface from mice undergoing abortion. Scandinavian journal of immunology. vol 61. issue 6. 2005-07-28. PMID:15963043. |
excessive production of th1 cytokines, particularly of tumour necrosis factor (tnf)-alpha, also triggers apoptosis. |
2005-07-28 |
2023-08-12 |
mouse |