| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shoshana Greenberger, Aviv Shaish, Nira Varda-Bloom, Keren Levanon, Eyal Breitbart, Iris Goldberg, Iris Barshack, Israel Hodish, Niva Yaacov, Livnat Bangio, Tanya Goncharov, David Wallach, Dror Harat. Transcription-controlled gene therapy against tumor angiogenesis. The Journal of clinical investigation. vol 113. issue 7. 2004-05-25. PMID:15057308. |
expression of a chimeric death receptor, composed of fas and tnf receptor 1, resulted in specific apoptosis of endothelial cells in vitro and sensitization of cells to the proapoptotic effect of tnf-alpha. |
2004-05-25 |
2023-08-12 |
mouse |
| Hannes Hentze, Markus Latta, Gerald Künstle, Saravanakumar Dhakshinamoorthy, Poh Yong Ng, Alan G Porter, Albrecht Wende. Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis. Hepatology (Baltimore, Md.). vol 39. issue 5. 2004-05-24. PMID:15122760. |
when incubated with cpt, murine hepatocytes displayed an inhibition of protein synthesis and were thereby rendered sensitive to apoptosis induction by tnf. |
2004-05-24 |
2023-08-12 |
mouse |
| Hannes Hentze, Markus Latta, Gerald Künstle, Saravanakumar Dhakshinamoorthy, Poh Yong Ng, Alan G Porter, Albrecht Wende. Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis. Hepatology (Baltimore, Md.). vol 39. issue 5. 2004-05-24. PMID:15122760. |
hepatocytes derived from tnf receptor-1 knockout mice were resistant to cpt/tnf-induced apoptosis. |
2004-05-24 |
2023-08-12 |
mouse |
| Tongtong Zou, Jaladanki N Rao, Xin Guo, Lan Liu, Huifang M Zhang, Eric D Strauch, Barbara L Bass, Jian-Ying Wan. NF-kappaB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion. American journal of physiology. Cell physiology. vol 286. issue 5. 2004-05-20. PMID:15075199. |
decreased levels of c-iap2 and xiap proteins by inactivation of nf-kappab through adikappabsr infection or treatment with the specific inhibitor smac also overcame the resistance of polyamine-depleted cells to apoptosis induced by the combination of tumor necrosis factor (tnf)-alpha and cycloheximide (chx). |
2004-05-20 |
2023-08-12 |
Not clear |
| Yong Lin, Swati Choksi, Han-Ming Shen, Qing-Feng Yang, Gang Min Hur, You Sun Kim, Jamie Hong Tran, Sergei A Nedospasov, Zheng-gang Li. Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. The Journal of biological chemistry. vol 279. issue 11. 2004-05-19. PMID:14701813. |
the mechanism of tumor necrosis factor (tnf)-induced nonapoptotic cell death is largely unknown, although the mechanism of tnf-induced apoptosis has been studied extensively. |
2004-05-19 |
2023-08-12 |
mouse |
| Keith Del Villar, Carol A Mille. Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 12. 2004-05-10. PMID:15007167. |
increased expression of several members of the tnf pathway and jnk activation of c-jun ultimately result in neuronal apoptosis. |
2004-05-10 |
2023-08-12 |
mouse |
| Y W Park, J D Ji, J S Lee, D W Ryang, D H Yo. Actinomycin D renders cultured synovial fibroblasts susceptible to tumour necrosis factor related apoptosis-inducing ligand (TRAIL)-induced apoptosis. Scandinavian journal of rheumatology. vol 32. issue 6. 2004-05-07. PMID:15080267. |
to investigate the expression of tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) receptors in cultured synovial fibroblasts from rheumatoid arthritis (ra) and osteoarthritis (oa) patients, and to examine their susceptibility to trail-induced apoptosis in the presence or absence of metabolic inhibitors. |
2004-05-07 |
2023-08-12 |
Not clear |
| J O'Sullivan, L Whyte, J Drake, M Tenniswoo. Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis. Cell death and differentiation. vol 10. issue 8. 2004-05-05. PMID:12867999. |
these studies describe the biogenesis and intracellular trafficking of clusterin in mcf-7 cells before and after the initiation of apoptosis with antiestrogens and tnf alpha. |
2004-05-05 |
2023-08-12 |
Not clear |
| Stephen J Turner, Nicole L La Gruta, John Stambas, Gabriela Diaz, Peter C Dohert. Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8+ effector T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 10. 2004-05-05. PMID:14993609. |
the d(b)pa(224)-specific cd8(+) effector t cells make more tumor necrosis factor (tnf) alpha than the comparable cd8(+)d(b)np(366)(+) set, a difference reflected in the greater sensitivity of the cd8(+)d(b)pa(224)(+) population to tnf receptor (tnfr) 2-mediated apoptosis under conditions of in vitro culture. |
2004-05-05 |
2023-08-12 |
mouse |
| Nicholas J Donato, Jim Klostergaar. Distinct stress and cell destruction pathways are engaged by TNF and ceramide during apoptosis of MCF-7 cells. Experimental cell research. vol 294. issue 2. 2004-05-05. PMID:15023539. |
distinct stress and cell destruction pathways are engaged by tnf and ceramide during apoptosis of mcf-7 cells. |
2004-05-05 |
2023-08-12 |
human |
| Nicholas J Donato, Jim Klostergaar. Distinct stress and cell destruction pathways are engaged by TNF and ceramide during apoptosis of MCF-7 cells. Experimental cell research. vol 294. issue 2. 2004-05-05. PMID:15023539. |
ceramide has been proposed to be an important signaling intermediate in tumor necrosis factor (tnf)-induced apoptosis in human mcf-7 breast adenocarcinoma cells. |
2004-05-05 |
2023-08-12 |
human |
| Hidenobu Kamohara, Wataru Matsuyama, Osamu Shimozato, Koichiro Abe, Carole Galligan, Shin-Ichi Hashimoto, Kouji Matsushima, Teizo Yoshimur. Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptor expression in human neutrophils. Immunology. vol 111. issue 2. 2004-05-03. PMID:15027904. |
tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf superfamily, which is capable of inducing apoptosis in many cell types, including tumour and virus-infected cells, but rarely in normal cells. |
2004-05-03 |
2023-08-12 |
human |
| Harry L A Janssen, Hajime Higuchi, Ahmad Abdulkarim, Gregory J Gore. Hepatitis B virus enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity by increasing TRAIL-R1/death receptor 4 expression. Journal of hepatology. vol 39. issue 3. 2004-04-30. PMID:12927928. |
apoptosis by death receptors, such as fas and tumor necrosis factor (tnf)-alpha receptor-1, play a significant role in the pathogenesis of hepatitis b virus (hbv)-infections. |
2004-04-30 |
2023-08-12 |
Not clear |
| M A McDonnell, D Wang, S M Khan, M G Vander Heiden, A Keleka. Caspase-9 is activated in a cytochrome c-independent manner early during TNFalpha-induced apoptosis in murine cells. Cell death and differentiation. vol 10. issue 9. 2004-04-16. PMID:12934075. |
fl5.12 pro-b lymphoma cells utilize the mitochondrial pathway to apoptosis in response to tumor necrosis factor (tnf) receptor occupation, yet high levels of the bcl-2 family antiapoptotic protein, bcl-x(l), fail to protect these cells against tnf-receptor-activated death. |
2004-04-16 |
2023-08-12 |
Not clear |
| Pamela Fischer-Posovszky, Hans Tornqvist, Klaus-Michael Debatin, Martin Wabitsc. Inhibition of death-receptor mediated apoptosis in human adipocytes by the insulin-like growth factor I (IGF-I)/IGF-I receptor autocrine circuit. Endocrinology. vol 145. issue 4. 2004-04-16. PMID:14691011. |
we found that death receptors (cd95, tnf-related apoptosis-inducing ligand receptors 1 and 2, and tnf receptor 1) are expressed in human fat cells and that apoptosis can be induced by specific ligands. |
2004-04-16 |
2023-08-12 |
human |
| Eugene E Varfolomeev, Avi Ashkenaz. Tumor necrosis factor: an apoptosis JuNKie? Cell. vol 116. issue 4. 2004-04-15. PMID:14980217. |
tnf also can trigger apoptosis through caspase-8, but the role and underlying mechanism of this activity are not fully understood. |
2004-04-15 |
2023-08-12 |
Not clear |
| Eugene E Varfolomeev, Avi Ashkenaz. Tumor necrosis factor: an apoptosis JuNKie? Cell. vol 116. issue 4. 2004-04-15. PMID:14980217. |
here, we review recent data on the role of jnk in the regulation of tnf-dependent apoptosis and discuss what is known so far about how cells decide whether to live or die in response to tnf. |
2004-04-15 |
2023-08-12 |
Not clear |
| Chulhee Choi, Etty N Benvenist. Fas ligand/Fas system in the brain: regulator of immune and apoptotic responses. Brain research. Brain research reviews. vol 44. issue 1. 2004-04-14. PMID:14739003. |
the external pathway is mainly triggered by ligation of death receptors such as fas, tumor necrosis factor (tnf)-related apoptosis inducing ligand-r1 (trail-r1), trail-r2 and tnfrp55, and mediated by direct activation of upstream caspases. |
2004-04-14 |
2023-08-12 |
Not clear |
| Rita N Bárcia, Nicola S Della Valle, Julie D McLeo. Caspase involvement in RIP-associated CD95-induced T cell apoptosis. Cellular immunology. vol 226. issue 2. 2004-04-13. PMID:14962495. |
although, rip is best known for its role in tnf signalling and nf-kappab activation, it contains a death domain and it is capable of causing apoptosis upon cleavage. |
2004-04-13 |
2023-08-12 |
Not clear |
| Robert R Myers, Yasufumi Sekiguchi, Shinichi Kikuchi, Brian Scott, Satya Medicherla, Andrew Protter, W Marie Campan. Inhibition of p38 MAP kinase activity enhances axonal regeneration. Experimental neurology. vol 184. issue 2. 2004-04-02. PMID:14769353. |
tnf dose-dependently induces schwann cell and macrophage activation in vivo and apoptosis in primary sc cultures in vitro, while inhibition of p38 mapk is thought to block these cellular processes. |
2004-04-02 |
2023-08-12 |
Not clear |