| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qinjie Weng, Mengting Zhao, Jiahuan Zheng, Lijun Yang, Zijie Xu, Zhikang Zhang, Jincheng Wang, Jiajia Wang, Bo Yang, Q Richard Lu, Meidan Ying, Qiaojun H. STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia. Cell death and differentiation. vol 27. issue 1. 2021-04-02. PMID:31097787. |
notably, the defective secretion of insulin and β-cells apoptosis was completely rescued by pten ablation in stat3-null islets or pten inhibitor bpv(phen) treatment. |
2021-04-02 |
2023-08-13 |
mouse |
| Yang Zou, Rong Li, Dabin Kuang, Meiling Zuo, Wenqun Li, Wei Tong, Li Jiang, Min Zhou, Yin Chen, Wencheng Gong, Lijuan Liu, Fangfang To. Galangin Inhibits Cholangiocarcinoma Cell Growth and Metastasis through Downregulation of MicroRNA-21 Expression. BioMed research international. vol 2020. 2021-04-01. PMID:32626749. |
mechanically, galangin increases the expression of phosphatase and tensin homolog (pten), a direct target of mir-21, resulting in decreased phosphorylation of akt, a protein kinase which plays a critical role in controlling survival and apoptosis. |
2021-04-01 |
2023-08-13 |
Not clear |
| Meng Zhang, Lin Wang, Sihua Huang, Xijing H. Exosomes with high level of miR-181c from bone marrow-derived mesenchymal stem cells inhibit inflammation and apoptosis to alleviate spinal cord injury. Journal of molecular histology. vol 52. issue 2. 2021-04-01. PMID:33548000. |
it was related to the inhibition of pten and the suppression of nf-κb signal, and finally decreasing inflammation and apoptosis in spinal cord and improved sci. |
2021-04-01 |
2023-08-13 |
rat |
| Hong Wei, Yuhao Xu, Qi Chen, Hui Chen, Xiaolan Zhu, Yuefeng L. Mesenchymal stem cell-derived exosomal miR-223 regulates neuronal cell apoptosis. Cell death & disease. vol 11. issue 4. 2021-03-31. PMID:32341353. |
furthermore, msc-derived exosomal mir-223 inhibited the apoptosis of neurons in vitro by targeting pten, thus activating the pi3k/akt pathway. |
2021-03-31 |
2023-08-13 |
Not clear |
| K Han, F-R Wang, M-Q Yu, B X. LncRNA MEG3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating PTEN. European review for medical and pharmacological sciences. vol 24. issue 10. 2021-03-31. PMID:32495857. |
lncrna meg3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating pten. |
2021-03-31 |
2023-08-13 |
rat |
| K Han, F-R Wang, M-Q Yu, B X. LncRNA MEG3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating PTEN. European review for medical and pharmacological sciences. vol 24. issue 10. 2021-03-31. PMID:32495857. |
to study the influences of long non-coding ribonucleic acid (lncrna) maternally expressed gene 3 (meg3) on the proliferation and apoptosis of synovial cells in rats with knee osteoarthritis by regulating phosphate and tension homology deleted on chromosome ten (pten). |
2021-03-31 |
2023-08-13 |
rat |
| Y-Y Sun, J Pan, W Wei, S-S Yu, S-D Mao, N Zhang, L-M A. Effects of miR-32 targeting PTEN on proliferation and apoptosis of myeloma cells. European review for medical and pharmacological sciences. vol 24. issue 7. 2021-03-29. PMID:32329824. |
effects of mir-32 targeting pten on proliferation and apoptosis of myeloma cells. |
2021-03-29 |
2023-08-13 |
Not clear |
| Y-Y Sun, J Pan, W Wei, S-S Yu, S-D Mao, N Zhang, L-M A. Effects of miR-32 targeting PTEN on proliferation and apoptosis of myeloma cells. European review for medical and pharmacological sciences. vol 24. issue 7. 2021-03-29. PMID:32329824. |
to explore the effects of micro ribonucleic acid (mir)-32 on the proliferation and apoptosis of myeloma cells, and to verify whether it exerts its function by targeting phosphatase and tensin homolog deleted on chromosome ten (pten). |
2021-03-29 |
2023-08-13 |
Not clear |
| Xiaoxin Shi, Amir Valizadeh, Seyed Mostafa Mir, Zatollah Asemi, Ansar Karimian, Maryam Majidina, Amin Safa, Bahman Yosef. miRNA-29a reverses P-glycoprotein-mediated drug resistance and inhibits proliferation via up-regulation of PTEN in colon cancer cells. European journal of pharmacology. vol 880. 2021-03-24. PMID:32416187. |
these results have indicated that mir-29a target pten ultimately p-gp, which is downstream of pten, inhibit drug resistance, proliferation, and apoptosis through pi3k/akt pathway. |
2021-03-24 |
2023-08-13 |
Not clear |
| Shaoxuan He, Zhihua Wang, Yunxuan Li, Junjie Dong, Dong Xiang, Lirong Ren, Limin Guo, Jun Sh. MicroRNA-92a-3p enhances functional recovery and suppresses apoptosis after spinal cord injury via targeting phosphatase and tensin homolog. Bioscience reports. vol 40. issue 5. 2021-03-23. PMID:32297644. |
we further assessed the effects of agomir-92 or/and overexpressed pten on apoptosis rates and apoptotic protein expressions in sci mice. |
2021-03-23 |
2023-08-13 |
mouse |
| Xin Meng, Lijun Mei, Chedong Zhao, Wei Chen, Ning Zhan. miR-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of PTEN and BCL2L11 and modulation of AKT/mTOR signaling. Journal of cellular physiology. vol 235. issue 11. 2021-03-12. PMID:31960416. |
mir-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of pten and bcl2l11 and modulation of akt/mtor signaling. |
2021-03-12 |
2023-08-13 |
human |
| Xin Meng, Lijun Mei, Chedong Zhao, Wei Chen, Ning Zhan. miR-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of PTEN and BCL2L11 and modulation of AKT/mTOR signaling. Journal of cellular physiology. vol 235. issue 11. 2021-03-12. PMID:31960416. |
in conclusion, the present study for the first time showed the downregulation of mir-885 induced by h/r in hcms, and provided the evidence that mir-885 attenuated h/r-induced cell apoptosis via inhibiting pten and blc2l11 and modulation of akt/mtor signaling in hcms. |
2021-03-12 |
2023-08-13 |
human |
| Pei Li, Jing Wang, Xia Zhao, Jing Ru, Tian Tian, Yun An, Liying Tang, Yuzhi Ba. PTEN inhibition attenuates endothelial cell apoptosis in coronary heart disease via modulating the AMPK-CREB-Mfn2-mitophagy signaling pathway. Journal of cellular physiology. vol 235. issue 5. 2021-03-08. PMID:31654396. |
pten inhibition attenuates endothelial cell apoptosis in coronary heart disease via modulating the ampk-creb-mfn2-mitophagy signaling pathway. |
2021-03-08 |
2023-08-13 |
human |
| Zhiqiang Li, Hongqiang Li, Baoxin Liu, Jiachen Luo, Xiaoming Qin, Mengmeng Gong, Beibei Shi, Yidong We. Inhibition of miR-25 attenuates doxorubicin-induced apoptosis, reactive oxygen species production and DNA damage by targeting PTEN. International journal of medical sciences. vol 17. issue 10. 2021-03-08. PMID:32624698. |
inhibition of mir-25 attenuates doxorubicin-induced apoptosis, reactive oxygen species production and dna damage by targeting pten. |
2021-03-08 |
2023-08-13 |
Not clear |
| K Han, F-R Wang, M-Q Yu, B X. Expression of Concern: LncRNA MEG3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating PTEN. European review for medical and pharmacological sciences. vol 24. issue 17. 2021-03-08. PMID:32964944. |
expression of concern: lncrna meg3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating pten. |
2021-03-08 |
2023-08-13 |
rat |
| K Han, F-R Wang, M-Q Yu, B X. Expression of Concern: LncRNA MEG3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating PTEN. European review for medical and pharmacological sciences. vol 24. issue 17. 2021-03-08. PMID:32964944. |
the editorial board of european review for medical and pharmacological sciences would like to issue an expression of concern for "lncrna meg3 inhibits proliferation and promotes apoptosis of synovial cells in rats with knee osteoarthritis by regulating pten", by k. han, f.-r. wang, m.-q. |
2021-03-08 |
2023-08-13 |
rat |
| Ye Zhou, Meng Zhang, Zhilei Zhang, Yuming Jia, Chong Zhang, Li Pen. Hydrazinocurcumin and 5-fluorouracil enhance apoptosis and restrain tumorigenicity of HepG2 cells via disrupting the PTEN-mediated PI3K/Akt signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32559627. |
we found that hzc or 5-fu induced apoptosis and repressed proliferation of hepg2 cells by upregulating the expression of pten and disrupting the pi3k/akt signaling pathway activation. |
2021-02-26 |
2023-08-13 |
mouse |
| Ye Zhou, Meng Zhang, Zhilei Zhang, Yuming Jia, Chong Zhang, Li Pen. Hydrazinocurcumin and 5-fluorouracil enhance apoptosis and restrain tumorigenicity of HepG2 cells via disrupting the PTEN-mediated PI3K/Akt signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32559627. |
thus, hzc and 5-fu increase pten, which blocks the pi3k/akt signaling pathway, ultimately inducing hepg2 cell apoptosis. |
2021-02-26 |
2023-08-13 |
mouse |
| Jianming Huang, Zhiyang Ye, Jun Wang, Qichuan Chen, Danlei Huang, Haoyuan Li. USP13 mediates PTEN to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via AKT-dependent manner. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33378983. |
usp13 mediates pten to ameliorate osteoarthritis by restraining oxidative stress, apoptosis and inflammation via akt-dependent manner. |
2021-02-24 |
2023-08-13 |
mouse |
| Tiejun Liu, Xiaoliu Dong, Bin Wang, Shubo Zhang, Jing Bai, Wei Ma, Xiaojing Zhao, Xiaotao Wan. Silencing of PTEN inhibits the oxidative stress damage and hippocampal cell apoptosis induced by Sevoflurane through activating MEK1/ERK signaling pathway in infant rats. Cell cycle (Georgetown, Tex.). vol 19. issue 6. 2021-02-23. PMID:32089060. |
silencing of pten inhibits the oxidative stress damage and hippocampal cell apoptosis induced by sevoflurane through activating mek1/erk signaling pathway in infant rats. |
2021-02-23 |
2023-08-13 |
rat |