| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Moon-Jung Goo, Jin-Kyu Park, Il-Hwa Hong, Ah-Young Kim, Eun-Mi Lee, Eun-Joo Lee, Meeyul Hwang, Kyu-Shik Jeon. Increased susceptibility of radiation-induced intestinal apoptosis in SMP30 KO mice. International journal of molecular sciences. vol 14. issue 6. 2015-06-24. PMID:23708106. |
increased susceptibility of radiation-induced intestinal apoptosis in smp30 ko mice. |
2015-06-24 |
2023-08-12 |
mouse |
| Moon-Jung Goo, Jin-Kyu Park, Il-Hwa Hong, Ah-Young Kim, Eun-Mi Lee, Eun-Joo Lee, Meeyul Hwang, Kyu-Shik Jeon. Increased susceptibility of radiation-induced intestinal apoptosis in SMP30 KO mice. International journal of molecular sciences. vol 14. issue 6. 2015-06-24. PMID:23708106. |
recently, senescence marker protein-30 (smp30) knockout (ko) mice have been reported to be susceptible to apoptosis, however, the role of smp30 has not been characterized in the small intestine. |
2015-06-24 |
2023-08-12 |
mouse |
| Moon-Jung Goo, Jin-Kyu Park, Il-Hwa Hong, Ah-Young Kim, Eun-Mi Lee, Eun-Joo Lee, Meeyul Hwang, Kyu-Shik Jeon. Increased susceptibility of radiation-induced intestinal apoptosis in SMP30 KO mice. International journal of molecular sciences. vol 14. issue 6. 2015-06-24. PMID:23708106. |
apoptosis in the crypts of the small intestine increased in the 0 to 5 gy radiated smp30 ko and wt mice. |
2015-06-24 |
2023-08-12 |
mouse |
| Moon-Jung Goo, Jin-Kyu Park, Il-Hwa Hong, Ah-Young Kim, Eun-Mi Lee, Eun-Joo Lee, Meeyul Hwang, Kyu-Shik Jeon. Increased susceptibility of radiation-induced intestinal apoptosis in SMP30 KO mice. International journal of molecular sciences. vol 14. issue 6. 2015-06-24. PMID:23708106. |
radiation-induced apoptosis and the bax/bcl-2 ratio in the smp30 ko mice were significantly increased in comparison to each identically treated group of wt mice (p < 0.05). |
2015-06-24 |
2023-08-12 |
mouse |
| Moon-Jung Goo, Jin-Kyu Park, Il-Hwa Hong, Ah-Young Kim, Eun-Mi Lee, Eun-Joo Lee, Meeyul Hwang, Kyu-Shik Jeon. Increased susceptibility of radiation-induced intestinal apoptosis in SMP30 KO mice. International journal of molecular sciences. vol 14. issue 6. 2015-06-24. PMID:23708106. |
the levels of spontaneous apoptosis in both wt and ko mice were similar (p > 0.05), indicating that increased apoptosis of crypt cells of smp30 ko by irradiation can be associated with smp30 depletion. |
2015-06-24 |
2023-08-12 |
mouse |
| Zhanguo Gao, Jin Zhang, Tara M Henagan, Jong Han Lee, Xin Ye, Hui Wang, Jianping Y. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. American journal of physiology. Endocrinology and metabolism. vol 308. issue 6. 2015-06-15. PMID:25564477. |
in the mechanism of enhanced inflammation, adipocytes and macrophages exhibited an increase in cellular apoptosis, which was observed with more formation of crown-like structures (cls) in fat tissue of ko mice. |
2015-06-15 |
2023-08-13 |
mouse |
| Takashi D Y Kozai, Xia Li, Lance M Bodily, Ellen M Caparosa, Georgios A Zenonos, Diane L Carlisle, Robert M Friedlander, X Tracy Cu. Effects of caspase-1 knockout on chronic neural recording quality and longevity: insight into cellular and molecular mechanisms of the reactive tissue response. Biomaterials. vol 35. issue 36. 2015-05-20. PMID:25176060. |
caspase-1 knockout (ko) mice are resistant to apoptosis and these mice have preserved neurologic function by reducing ischemia-induced brain injury in stroke models. |
2015-05-20 |
2023-08-13 |
mouse |
| Guang Yang, Chhanda Biswasa, Qing Sara Lin, Ping La, Fumihiko Namba, Tiangang Zhuang, Manasa Muthu, Phyllis A Denner. Heme oxygenase-1 regulates postnatal lung repair after hyperoxia: role of β-catenin/hnRNPK signaling. Redox biology. vol 1. 2015-05-13. PMID:24024157. |
although it was not observed after 3 days of hyperoxia alone, when exposed to hyperoxia and allowed to recover in air (o2/air recovered), neonatal ho-1 knockout (ko) mice had enlarged alveolar spaces and increased lung apoptosis as well as decreased lung protein translation and dysregulated gene expression in the recovery phase of the injury. |
2015-05-13 |
2023-08-12 |
mouse |
| Dong-In Koh, Dohyun Han, Hoon Ryu, Won-Il Choi, Bu-Nam Jeon, Min-Kyeong Kim, Youngsoo Kim, Jin Young Kim, Lee Parry, Alan R Clarke, Albert B Reynolds, Man-Wook Hu. KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 42. 2015-04-24. PMID:25288747. |
analogously, in kaiso ko mouse embryonic fibroblast cells, p53-to-promoter binding and up-regulation of p21 and apoptosis gene expression is significantly compromised. |
2015-04-24 |
2023-08-13 |
mouse |
| Lei Lv, Qiurong Meng, Meng Ye, Peng Wang, Guanhua Xu. STAT4 deficiency protects against neointima formation following arterial injury in mice. Journal of molecular and cellular cardiology. vol 74. 2015-03-30. PMID:24933129. |
vsmc apoptosis was enhanced in the vasculature postinjury in stat4 ko mice compared with wt mice. |
2015-03-30 |
2023-08-13 |
mouse |
| Yujing Sun, Masako Nakanishi, Fuyuki Sato, Kosuke Oikawa, Yasuteru Muragaki, Gengyin Zho. Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression. Biochemical and biophysical research communications. vol 456. issue 3. 2015-03-20. PMID:25514040. |
furthermore, decreased cell proliferation, and increased apoptosis in ko skin was rescued by noggin treatment. |
2015-03-20 |
2023-08-13 |
mouse |
| Yuan Ying, Jinu Kim, Sherry N Westphal, Kelly E Long, Babu J Padanila. Targeted deletion of p53 in the proximal tubule prevents ischemic renal injury. Journal of the American Society of Nephrology : JASN. vol 25. issue 12. 2015-02-23. PMID:24854277. |
apoptosis and expression of proapoptotic p53 targets, including bid and siva, were also significantly reduced, and cell cycle arrest at the g2/m phase was attenuated in p53 ko ischemic kidneys. |
2015-02-23 |
2023-08-13 |
mouse |
| Lin Yan, Stephen F Vatner, Dorothy E Vatne. Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. American journal of physiology. Heart and circulatory physiology. vol 307. issue 10. 2015-01-15. PMID:25193472. |
the β₂-ar tg × ac5 ko bigenic mice prevented the cardiomyopathy as reflected by improved lv ejection fraction, reduced apoptosis, fibrosis, and myocyte size and preserved exercise capacity. |
2015-01-15 |
2023-08-13 |
mouse |
| Guoyong Yin, Tzong-Jen Sheu, Prashanthi Menon, Jinjiang Pang, Hsin-Chiu Ho, Shanshan Shi, Chao Xie, Elaine Smolock, Chen Yan, Michael J Zuscik, Bradford C Ber. Impaired angiogenesis during fracture healing in GPCR kinase 2 interacting protein-1 (GIT1) knock out mice. PloS one. vol 9. issue 2. 2015-01-10. PMID:24586541. |
git1 ko mice also showed a decrease in chondrocyte proliferation and apoptosis at days 7 and 14, as determined by pcna and tunel staining. |
2015-01-10 |
2023-08-12 |
mouse |
| Tom P Theruvath, Venkat K Ramshesh, Zhi Zhong, Robert T Currin, Thomas Karrasch, John J Lemaster. Icam-1 upregulation in ethanol-induced Fatty murine livers promotes injury and sinusoidal leukocyte adherence after transplantation. HPB surgery : a world journal of hepatic, pancreatic and biliary surgery. vol 2012. 2014-10-31. PMID:22778492. |
apoptosis also decreased by 75% (p < 0.05), and 4-hne staining after lt was also decreased in ethanol-treated ko grafts compared to wt. |
2014-10-31 |
2023-08-12 |
mouse |
| Radnaa Enkhtuya, Tokiharu Sato, Mitsuo Wakasugi, Baljinnyam Tuvshintugs, Hirofumi Miyata, Takeshi Sakurai, Tsukasa Matsunaga, Katsuji Yoshiok. The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice. Genes to cells : devoted to molecular & cellular mechanisms. vol 19. issue 4. 2014-10-06. PMID:24520900. |
we found that uvb-induced skin epidermal apoptosis was prevented in jlp knockout (ko) as well as in keratinocyte-specific jlp ko mice. |
2014-10-06 |
2023-08-12 |
mouse |
| Radnaa Enkhtuya, Tokiharu Sato, Mitsuo Wakasugi, Baljinnyam Tuvshintugs, Hirofumi Miyata, Takeshi Sakurai, Tsukasa Matsunaga, Katsuji Yoshiok. The scaffold protein JLP plays a key role in regulating ultraviolet B-induced apoptosis in mice. Genes to cells : devoted to molecular & cellular mechanisms. vol 19. issue 4. 2014-10-06. PMID:24520900. |
moreover, topical treatment of uvb-irradiated mouse skin with a p38 inhibitor significantly suppressed the epidermal apoptosis in wild-type mice, but not in jlp ko mice. |
2014-10-06 |
2023-08-12 |
mouse |
| Lufang Chen, Xiaodong Lu, Tiantian Zeng, Yuanyuan Chen, Qian Chen, Weijiang Wu, Xun Yan, Honghua Cai, Zhijian Zhang, Qixiang Shao, Wenxin Qi. Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis. Oncology reports. vol 31. issue 2. 2014-09-03. PMID:24337404. |
pcna and edu assays indicated more active proliferation whereas tunel assay revealed decreased apoptosis in lass2 ko livers, when compared with the wt control. |
2014-09-03 |
2023-08-12 |
mouse |
| Satoshi Okumura, Takayuki Fujita, Wenqian Cai, Meihua Jin, Iyuki Namekata, Yasumasa Mototani, Huiling Jin, Yoshiki Ohnuki, Yayoi Tsuneoka, Reiko Kurotani, Kenji Suita, Yuko Kawakami, Shogo Hamaguchi, Takaya Abe, Hiroshi Kiyonari, Takashi Tsunematsu, Yunzhe Bai, Sayaka Suzuki, Yuko Hidaka, Masanari Umemura, Yasuhiro Ichikawa, Utako Yokoyama, Motohiko Sato, Fumio Ishikawa, Hiroko Izumi-Nakaseko, Satomi Adachi-Akahane, Hikaru Tanaka, Yoshihiro Ishikaw. Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses. The Journal of clinical investigation. vol 124. issue 6. 2014-08-18. PMID:24892712. |
compared with wt mice, aortic banding induced a similar degree of cardiac hypertrophy in epac1 ko; however, lack of epac1 prevented subsequent cardiac dysfunction as a result of decreased cardiac myocyte apoptosis and fibrosis. |
2014-08-18 |
2023-08-13 |
mouse |
| Yogesh M Kulkarni, Changxing Liu, Qi Qi, Yanmei Zhu, David J Klinke, Jun Li. Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis. The Analyst. vol 138. issue 22. 2014-08-15. PMID:24091439. |
differential proteomic analysis of caveolin-1 ko cells reveals sh2b3 and clec12b as novel interaction partners of caveolin-1 and capns1 as a potential mediator of caveolin-1-induced apoptosis. |
2014-08-15 |
2023-08-12 |
mouse |