| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Hu, N A Zhang, Ronglin Wang, Fei Huang, Guang L. Paclitaxel induces apoptosis and reduces proliferation by targeting epidermal growth factor receptor signaling pathway in oral cavity squamous cell carcinoma. Oncology letters. vol 10. issue 4. 2020-09-29. PMID:26622855. |
paclitaxel inhibited the growth of the oral cancer cell line, tea8113 malignant proliferation and enhanced tea8113 cell apoptosis through inhibiting the egfr signaling pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yitao Wan, Yuan Yuan, Yueyin Pan, Ying Zhan. Antitumor activity of high-dose pulsatile gefitinib in non-small-cell lung cancer with acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Experimental and therapeutic medicine. vol 13. issue 6. 2020-09-29. PMID:28587381. |
cell apoptosis and cycling were also determined by flow cytometry and the expression of phospho (p)-egfr, egfr, p-akt and akt were measured by western blot analysis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yitao Wan, Yuan Yuan, Yueyin Pan, Ying Zhan. Antitumor activity of high-dose pulsatile gefitinib in non-small-cell lung cancer with acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Experimental and therapeutic medicine. vol 13. issue 6. 2020-09-29. PMID:28587381. |
furthermore, high-dose pulsatile gefitinib may inhibit tumor growth and induce cell apoptosis by blocking the egfr signaling pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| Nannan Guo, Yingnan Zhao, Wen Zhang, Shaojun Li, Shanshan Li, Jianqi Y. MicroRNA-133a downregulated EGFR expression in human non-small cell lung cancer cells via AKT/ERK signaling. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30333876. |
to the best of our knowledge, the present study was the first to explore the role of mirna-133a/epidermal growth factor receptor (egfr) in regulating nsclc cell growth and apoptosis via the akt/extracellular signal-regulated kinase (erk) signaling pathway. |
2020-09-29 |
2023-08-13 |
human |
| Shinjini Ganguly, Ayan Chandra, Indu B Chatterje. Pathobiology of cigarette smoke-induced invasive cancer of the renal pelvis and its prevention by vitamin C. Toxicology reports. vol 5. 2020-09-29. PMID:30338226. |
as observed earlier with p-bq treatment, the initial events of cs exposure were oxidative damage and apoptosis that was followed by persistent signaling through egfr and map kinase pathway. |
2020-09-29 |
2023-08-13 |
Not clear |
| Youping Yang, Feng Zhu, Qingmei Wang, Yan Ding, Rongbiao Ying, Linghui Zen. Inhibition of EZH2 and EGFR produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells. OncoTargets and therapy. vol 11. 2020-09-29. PMID:30555238. |
inhibition of ezh2 and egfr produces a synergistic effect on cell apoptosis by increasing autophagy in gastric cancer cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Sijia Wang, Zhuoli Zhang, Han Peng, Kang Zen. Recent advances on the roles of epidermal growth factor receptor in psoriasis. American journal of translational research. vol 11. issue 2. 2020-09-28. PMID:30899359. |
epidermal growth factor receptor (egfr) is a well-characterized receptor tyrosine kinase that involved in many vital activities in cell development, such as cellular homeostasis, proliferation, division, differentiation and apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Lisa Salvatore, Maria Alessandra Calegari, Fotios Loupakis, Matteo Fassan, Brunella Di Stefano, Maria Bensi, Emilio Bria, Giampaolo Tortor. PTEN in Colorectal Cancer: Shedding Light on Its Role as Predictor and Target. Cancers. vol 11. issue 11. 2020-09-28. PMID:31717544. |
pten (phosphatase and tensin homologue), a tumor suppressor, regulating cell division and apoptosis, has been explored, and significant evidence suggests a role in cetuximab and panitumumab resistance linked to the epidermal growth factor receptor (egfr) signal transduction pathway. |
2020-09-28 |
2023-08-13 |
Not clear |
| Mohanad Mundher Abdulghani, Mohamad Natiq Abbas, Wafaa Redha Mohamme. Immunohistochemical Expression of Epidermal Growth Factor Receptor in Astrocytic Tumors in Iraqi Patients. Open access Macedonian journal of medical sciences. vol 7. issue 21. 2020-09-28. PMID:32010368. |
when activated, epidermal growth factor receptor (egfr) triggers several signalling cascades leading to increased proliferation and angiogenesis and decreased apoptosis and hence associated with aggressive progression of the tumour. |
2020-09-28 |
2023-08-13 |
human |
| Mark C Howell, Ryan Green, Roukiah Khalil, Elspeth Foran, Waise Quarni, Rajesh Nair, Stanley Stevens, Aleksandr Grinchuk, Andrew Hanna, Shyam Mohapatra, Subhra Mohapatr. Lung cancer cells survive epidermal growth factor receptor tyrosine kinase inhibitor exposure through upregulation of cholesterol synthesis. FASEB bioAdvances. vol 2. issue 2. 2020-09-28. PMID:32123859. |
in both parental and dt cells, ketoconazole and egfr tkis acted synergistically to induce apoptosis and overcome the development of egfr tolerance. |
2020-09-28 |
2023-08-13 |
mouse |
| Se Hyang Hong, Jin Mo Ku, Ye Seul Lim, Seo Yeon Lee, Ji Hye Kim, Chunhoo Cheon, Seong-Gyu K. Cucurbitacin D Overcomes Gefitinib Resistance by Blocking EGF Binding to EGFR and Inducing Cell Death in NSCLCs. Frontiers in oncology. vol 10. 2020-09-28. PMID:32133284. |
cud inhibits the phosphorylation of egfr in gefitinib-resistant nsclc cells and induces cell death via cell cycle arrest and apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Feng Gao, Ming Li, Wenbin Liu, Wei L. Inhibition of EGFR Signaling and Activation of Mitochondrial Apoptosis Contribute to Tanshinone IIA-Mediated Tumor Suppression in Non-Small Cell Lung Cancer Cells. OncoTargets and therapy. vol 13. 2020-09-28. PMID:32308411. |
inhibition of egfr signaling and activation of mitochondrial apoptosis contribute to tanshinone iia-mediated tumor suppression in non-small cell lung cancer cells. |
2020-09-28 |
2023-08-13 |
human |
| Fatemeh Shahsavari, Rosa Miri, Maedeh Ghorbanpou. Expression of epidermal growth factor receptor in oral and esophageal squamous-cell carcinoma. Dental research journal. vol 17. issue 2. 2020-09-28. PMID:32435429. |
epidermal growth factor receptor (egfr) plays a key role in numerous processes that affects tumor growth, progression, differentiation, invasion, metastasis, and inhibition of apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yun Yang, Ziyin Tian, Xinghua Zhao, Ya Li, Shuyan Dua. A novel antitumor dithiocarbamate compound inhibits the EGFR/AKT signaling pathway and induces apoptosis in esophageal cancer cells. Oncology letters. vol 20. issue 1. 2020-09-28. PMID:32566015. |
epidermal growth factor receptor (egfr) signaling pathway and apoptosis related protein levels were examined by western blotting. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jinqi Lv, Tianshu Guo, Xiujuan Qu, Xiaofang Che, Ce Li, Shuo Wang, Jing Gong, Peihong Wu, Yang Liu, Yunpeng Liu, Ling X. PD-L1 Under Regulation of miR-429 Influences the Sensitivity of Gastric Cancer Cells to TRAIL by Binding of EGFR. Frontiers in oncology. vol 10. 2020-09-28. PMID:32775300. |
epidermal growth factor receptor (egfr) antagonizes trail-induced apoptosis, but the mechanisms of these effects remain unclear. |
2020-09-28 |
2023-08-13 |
human |
| Jinqi Lv, Tianshu Guo, Xiujuan Qu, Xiaofang Che, Ce Li, Shuo Wang, Jing Gong, Peihong Wu, Yang Liu, Yunpeng Liu, Ling X. PD-L1 Under Regulation of miR-429 Influences the Sensitivity of Gastric Cancer Cells to TRAIL by Binding of EGFR. Frontiers in oncology. vol 10. 2020-09-28. PMID:32775300. |
this indicated that pd-l1 binds to and participates in egfr activation through mir-429 regulation to antagonize trail-induced apoptosis. |
2020-09-28 |
2023-08-13 |
human |
| Kaiyong Yang, Yan Chen, Jiaqian Zhou, Lin Ma, Yating Shan, Xiaoying Cheng, Yun Wang, Zhaoxin Zhang, Xiaojun Ji, Lili Chen, Hui Dai, Biqing Zhu, Chen Li, Zhonghua Tao, Xichun Hu, Wu Yi. Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations. British journal of pharmacology. vol 176. issue 24. 2020-09-24. PMID:31322286. |
ursolic acid promotes apoptosis and mediates transcriptional suppression of ct45a2 gene expression in non-small-cell lung carcinoma harbouring egfr t790m mutations. |
2020-09-24 |
2023-08-13 |
Not clear |
| Yanlin Feng, Yan Cheng, Yun Chang, Hui Jian, Runxiao Zheng, Xiaqing Wu, Keqiang Xu, Li Wang, Xiaomin Ma, Xi Li, Haiyuan Zhan. Time-staggered delivery of erlotinib and doxorubicin by gold nanocages with two smart polymers for reprogrammable release and synergistic with photothermal therapy. Biomaterials. vol 217. 2020-09-23. PMID:31299626. |
recently, it has been reported that cancer cells pretreated with epidermal growth factor receptor (egfr) inhibitor erlotinib (erl) can significantly synergize its apoptosis against the dna damaging agent doxorubicin (dox). |
2020-09-23 |
2023-08-13 |
Not clear |
| Hebat-Allah S Abbas, Somaia S Abd El-Kari. Design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents. Bioorganic chemistry. vol 89. 2020-09-22. PMID:31200286. |
design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential egfr inhibitors and apoptosis inducing agents. |
2020-09-22 |
2023-08-13 |
human |
| Yang-Ling Li, Ke Ding, Xiu Hu, Lin-Wen Wu, Dong-Mei Zhou, Ming-Jun Rao, Neng-Ming Lin, Chong Zhan. DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild-type NSCLC cells to AZD9291. Journal of cellular and molecular medicine. vol 23. issue 11. 2020-09-10. PMID:31454149. |
we showed that dyrk1a repression could enhance the anti-cancer effect of azd9291 by inducing apoptosis and suppressing cell proliferation in egfr wild-type nsclc cells. |
2020-09-10 |
2023-08-13 |
human |