| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Fen Liu, Aparna Purushotham, Angela A Wendel, Martha A Belur. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. American journal of physiology. Gastrointestinal and liver physiology. vol 292. issue 6. 2007-08-30. PMID:17322064. |
the ratio of bax to bcl2, a marker of apoptosis, was significantly increased in adipose of the cla-alone group and was partially prevented by treatment of rosi. |
2007-08-30 |
2023-08-12 |
mouse |
| Devarajan Karunagaran, Jeena Joseph, Thankayyan R Santhosh Kuma. Cell growth regulation. Advances in experimental medicine and biology. vol 595. 2007-07-03. PMID:17569215. |
curcumin-mediated regulation of apoptosis involves caspases, bcl2 family members, inhibitors of apoptosis proteins, and heat shock proteins. |
2007-07-03 |
2023-08-12 |
human |
| Mingjun Wang, Britta Johansen, Mogens H Nissen, Mette Thorn, Henrik Kløverpris, Anders Fomsgaard, Søren Buus, Mogens H Claësso. Identification of an HLA-A*0201 restricted Bcl2-derived epitope expressed on tumors. Cancer letters. vol 251. issue 1. 2007-06-28. PMID:17182178. |
the apoptosis inhibitory protein bcl2 is overexpressed in many human cancers as part of their neoplastic phenotype. |
2007-06-28 |
2023-08-12 |
mouse |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
moreover, conditioned medium obtained from lps-treated choriodecidua explants, but not that from amnion explants, decreased the number of viable cultured myometrial cells and induced cell apoptosis by inducing the overexpression of the proapoptotic protein bax and by decreasing the expression of the anti-apoptotic protein bcl2. |
2007-06-20 |
2023-08-12 |
human |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
exogenous tnf mimicked lps-treated choriodecidua-conditioned medium in that it induced myometrial cell apoptosis, reduced bcl2 expression, and increased bax expression. |
2007-06-20 |
2023-08-12 |
human |
| David M Feldser, Carol W Greide. Short telomeres limit tumor progression in vivo by inducing senescence. Cancer cell. vol 11. issue 5. 2007-06-14. PMID:17433785. |
expression of bcl2 blocked apoptosis in tumor cells, but surprisingly, mice with short telomeres were still resistant to tumor formation. |
2007-06-14 |
2023-08-12 |
mouse |
| P Obexer, K Geiger, P F Ambros, B Meister, M J Ausserlechne. FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells. Cell death and differentiation. vol 14. issue 3. 2007-06-08. PMID:16888645. |
however, expression of dnfadd did not inhibit fkhrl1-induced cell death, whereas bcl2 protected against apoptosis. |
2007-06-08 |
2023-08-12 |
human |
| Daisuke Iizuka, Osamu Inanami, Ikuo Kashiwakura, Mikinori Kuwabar. Purvalanol A enhances cell killing by inhibiting up-regulation of CDC2 kinase activity in tumor cells irradiated with high doses of X rays. Radiation research. vol 167. issue 5. 2007-06-08. PMID:17474786. |
the expression of anti-apoptosis proteins, inhibitor of apoptosis protein (iap) family members (survivin and xiap) and bcl2 family members (bcl-x(l) and bcl-2), in purvalanol a-treated cells with and without x rays was significantly lower than for cells exposed to x rays alone. |
2007-06-08 |
2023-08-12 |
Not clear |
| Wilson S Tsai, Wen-Shuz Yeow, Alex Chua, Rishindra M Reddy, Duc M Nguyen, David S Schrump, Dao M Nguye. Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. Molecular cancer therapeutics. vol 5. issue 12. 2007-06-07. PMID:17172403. |
profound combination-mediated cytotoxicity and induction of apoptosis was completely suppressed either by bcl2 overexpression or by inhibition of caspase-9 activity, which conclusively pointed to the essential role of the mitochondria-dependent death signaling cascade in this process. |
2007-06-07 |
2023-08-12 |
Not clear |
| Yoko Otake, Sridharan Soundararajan, Tapas K Sengupta, Ebenezer A Kio, James C Smith, Mauricio Pineda-Roman, Robert K Stuart, Eleanor K Spicer, Daniel J Fernande. Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA. Blood. vol 109. issue 7. 2007-05-31. PMID:17179226. |
b-cell chronic lymphocytic leukemia (cll) is characterized by the accumulation of clonal b cells that are resistant to apoptosis as a result of bcl2 oncogene overexpression. |
2007-05-31 |
2023-08-12 |
human |
| Sonja E N Wagenleiter, Peter Jagiello, Denis A Akkad, Larissa Arning, Thomas Griga, Wolfram Klein, Jörg T Epple. On the genetic involvement of apoptosis-related genes in Crohn's disease as revealed by an extended association screen using 245 markers: no evidence for new predisposing factors. Journal of negative results in biomedicine. vol 4. 2007-05-28. PMID:16318629. |
respective loci contribute to the activation/suppression of apoptosis, are involved in signal transduction and cell cycle regulators or they belong to the tumor necrosis factor superfamily, caspase related genes or the bcl2 family. |
2007-05-28 |
2023-08-12 |
Not clear |
| Anu Bashamboo, A Helen Taylor, Kay Samuel, Jean-Jacque Panthier, Anthony D Whetton, Lesley M Forreste. The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway. Journal of cell science. vol 119. issue Pt 15. 2007-05-16. PMID:16820414. |
differentiating kit null es cells exhibit elevated levels of dna laddering and reduced bcl2 expression, indicative of apoptosis. |
2007-05-16 |
2023-08-12 |
mouse |
| Simran Banga, Ping Gao, Xihui Shen, Valena Fiscus, Wei-Xing Zong, Lingling Chen, Zhao-Qing Lu. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 12. 2007-04-30. PMID:17360363. |
legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the bcl2 protein family. |
2007-04-30 |
2023-08-12 |
Not clear |
| Simran Banga, Ping Gao, Xihui Shen, Valena Fiscus, Wei-Xing Zong, Lingling Chen, Zhao-Qing Lu. Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 12. 2007-04-30. PMID:17360363. |
sidf contributes to apoptosis resistance in l. pneumophila-infected cells by specifically interacting with and neutralizing the effects of bnip3 and bcl-rambo, two proapoptotic members of bcl2 protein family. |
2007-04-30 |
2023-08-12 |
Not clear |
| Rishindra M Reddy, Wen-Shuz Yeow, Alex Chua, Duc M Nguyen, Aris Baras, M Firdos Ziauddin, Susan M Shamimi-Noori, Justin B Maxhimer, David S Schrump, Dao M Nguye. Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade. Apoptosis : an international journal on programmed cell death. vol 12. issue 1. 2007-04-24. PMID:17136498. |
profound tsa + apo2l/trail-mediated cytotoxicity and apoptosis were completely abrogated by either bcl2 over-expression or by the selective caspase 9 inhibitor, highlighting the essential role of mitochondria-dependent apoptosis signaling cascade in this process. |
2007-04-24 |
2023-08-12 |
Not clear |
| Ayesha N Shajahan, Aifen Wang, Markus Decker, Richard D Minshall, Minetta C Liu, Robert Clark. Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity. The Journal of biological chemistry. vol 282. issue 8. 2007-04-17. PMID:17190831. |
befitting its role as a multitasking molecule, we show that cav1 sensitizes cells to apoptosis by regulating cell cycle progression and activation of the apoptotic signaling molecules bcl2, p53, and p21. |
2007-04-17 |
2023-08-12 |
Not clear |
| Ayesha N Shajahan, Aifen Wang, Markus Decker, Richard D Minshall, Minetta C Liu, Robert Clark. Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity. The Journal of biological chemistry. vol 282. issue 8. 2007-04-17. PMID:17190831. |
we demonstrate that phosphorylated cav1 triggers apoptosis by inactivating bcl2 and increasing mitochondrial permeability more efficiently than non-phosphorylated cav1. |
2007-04-17 |
2023-08-12 |
Not clear |
| Ying Hu, Stefan Rahlfs, Volker Mersch-Sundermann, Katja Becke. Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells. Biological chemistry. vol 388. issue 2. 2007-04-06. PMID:17261084. |
among the 12 genes studied that are related to the cell cycle, differentiation and apoptosis, mrna levels of six genes, including p53, fas, and bcl2, were upregulated, while the mrna level of survivin was reduced. |
2007-04-06 |
2023-08-12 |
Not clear |
| Bo-Kyung Son, Koichi Kozaki, Katsuya Iijima, Masato Eto, Toru Nakano, Masahiro Akishita, Yasuyoshi Ouch. Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. European journal of pharmacology. vol 556. issue 1-3. 2007-04-05. PMID:17196959. |
the inhibitory effect of statins on pi-induced apoptosis was accompanied by restoration of the gas6-mediated survival signal pathway: upregulation of gas6 and axl expression, increased phosphorylation of akt and bcl2, and inhibition of bad and caspase 3 activation. |
2007-04-05 |
2023-08-12 |
human |
| B Mohana Kumar, Hai-Feng Jin, Jung-Gon Kim, Sun-A Ock, Yonggeun Hong, S Balasubramanian, Sang-Yong Choe, Gyu-Jin Rh. Differential gene expression patterns in porcine nuclear transfer embryos reconstructed with fetal fibroblasts and mesenchymal stem cells. Developmental dynamics : an official publication of the American Association of Anatomists. vol 236. issue 2. 2007-04-02. PMID:17191234. |
alterations in the expression pattern of genes implicated in transcription and pluripotency (oct4, stat3, nanog), dna methylation (dnmt1, dnmt3a), histone deacetylation (hdac2), growth factor signaling, and imprinting (igf2, igf2r) and apoptosis (bax, bcl2) regulation were observed in nt embryos. |
2007-04-02 |
2023-08-12 |
Not clear |