| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ehab Tousson, Bassem M Rafat, Mohamed Hessien, Ahmed A El Barbary, Ahmed Sam. P53 and Bcl2 apoptosis proteins in meso-2,3-dimercaptosuccinic acid treated lead-intoxicated rabbits. Toxicology and industrial health. vol 27. issue 3. 2011-07-12. PMID:21112928. |
p53 and bcl2 apoptosis proteins in meso-2,3-dimercaptosuccinic acid treated lead-intoxicated rabbits. |
2011-07-12 |
2023-08-12 |
Not clear |
| Ehab Tousson, Bassem M Rafat, Mohamed Hessien, Ahmed A El Barbary, Ahmed Sam. P53 and Bcl2 apoptosis proteins in meso-2,3-dimercaptosuccinic acid treated lead-intoxicated rabbits. Toxicology and industrial health. vol 27. issue 3. 2011-07-12. PMID:21112928. |
the effect of this treatment was investigated by measuring 2 of the apoptosis proteins p53 and bcl2. |
2011-07-12 |
2023-08-12 |
Not clear |
| Ehab Tousson, Bassem M Rafat, Mohamed Hessien, Ahmed A El Barbary, Ahmed Sam. P53 and Bcl2 apoptosis proteins in meso-2,3-dimercaptosuccinic acid treated lead-intoxicated rabbits. Toxicology and industrial health. vol 27. issue 3. 2011-07-12. PMID:21112928. |
our data indicate that exposure to rabbits to pb(ac)(2) caused a significant increase of apoptosis protein p53 and decrease in the antiapoptotic bcl2 proteins. |
2011-07-12 |
2023-08-12 |
Not clear |
| I-Chen Wu, Yang Zhao, Rihong Zhai, Geoffrey Liu, Monica Ter-Minassian, Kofi Asomaning, Li Su, Chen-Yu Liu, Feng Chen, Matthew H Kulke, Rebecca S Heist, David C Christian. Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma. Neoplasia (New York, N.Y.). vol 13. issue 4. 2011-07-11. PMID:21472143. |
among them, five snps in the nos3, bcl2, tnfrsf10a, and casp8 genes were known to be involved in apoptosis processes. |
2011-07-11 |
2023-08-12 |
Not clear |
| Janet E Davies, David C Rubinsztei. Over-expression of BCL2 rescues muscle weakness in a mouse model of oculopharyngeal muscular dystrophy. Human molecular genetics. vol 20. issue 6. 2011-06-20. PMID:21199860. |
genetically blocking apoptosis by over-expressing bcl2 ameliorates muscle weakness in our mouse model of opmd (a17 mice). |
2011-06-20 |
2023-08-12 |
mouse |
| Vivian Y Shin, Hong C Jin, Enders K O Ng, Chi H Cho, Wai K Leung, Joseph J Y Sung, Kent-Man Ch. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro. Cancer science. vol 102. issue 5. 2011-06-15. PMID:21261791. |
we found that nnk stimulated vascular endothelial growth factor (vegf) and angiogenesis, but suppressed apoptosis by increasing bcl2 and decreasing caspase-3 expressions. |
2011-06-15 |
2023-08-12 |
Not clear |
| Garabet Yeretssian, Ricardo G Correa, Karine Doiron, Patrick Fitzgerald, Christopher P Dillon, Douglas R Green, John C Reed, Maya Sale. Non-apoptotic role of BID in inflammation and innate immunity. Nature. vol 474. issue 7349. 2011-06-09. PMID:21552281. |
our results reveal a significant crosstalk between innate immunity and apoptosis and identify bid, a bcl2 family protein, as a critical component of the inflammatory response. |
2011-06-09 |
2023-08-12 |
mouse |
| Justin M Fear, Peter J Hanse. Developmental changes in expression of genes involved in regulation of apoptosis in the bovine preimplantation embryo. Biology of reproduction. vol 84. issue 1. 2011-05-16. PMID:20811013. |
results support the idea that changes in amounts of bcl2 family members are important for the inhibition of apoptosis in the 2-cell embryo and in the establishment of the capacity for apoptosis later in development. |
2011-05-16 |
2023-08-12 |
cattle |
| S Redondo, E Ruiz, A Gordillo-Moscoso, J Navarro-Dorado, M Ramajo, E Rodríguez, F Reguillo, M Carnero, M Casado, T Tejerin. Overproduction of cyclo-oxygenase-2 (COX-2) is involved in the resistance to apoptosis in vascular smooth muscle cells from diabetic patients: a link between inflammation and apoptosis. Diabetologia. vol 54. issue 1. 2011-05-11. PMID:20957341. |
vascular smooth muscle cells (vsmc) from diabetic patients are also resistant to apoptosis because of an increased abundance of b cell lymphoma 2 protein (bcl2). |
2011-05-11 |
2023-08-12 |
Not clear |
| Lilian Kuster, Reinhard Grausenburger, Gerhard Fuka, Ulrike Kaindl, Gerd Krapf, Andrea Inthal, Georg Mann, Maximilian Kauer, Johannes Rainer, Reinhard Kofler, Andrew Hall, Markus Metzler, Lüder Hinrich Meyer, Claus Meyer, Jochen Harbott, Rolf Marschalek, Sabine Strehl, Oskar A Haas, Renate Panzer-Grümaye. ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling. Blood. vol 117. issue 9. 2011-05-09. PMID:21224468. |
moreover, we identified recurrent, mainly nonoverlapping deletions associated with glucocorticoid-mediated apoptosis targeting the bcl2 modifying factor (bmf) (n=3), glucocorticoid receptor nr3c1 (n=4), and components of the mismatch repair pathways (n=3). |
2011-05-09 |
2023-08-12 |
Not clear |
| Reza Ardehali, Matthew A Inlay, Shah R Ali, Chad Tang, Micha Drukker, Irving L Weissma. Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 8. 2011-05-06. PMID:21300885. |
we find that bcl2 overexpression significantly decreases dissociation-induced apoptosis, resulting in enhanced colony formation from sorted single cells, and enhanced embryoid body formation. |
2011-05-06 |
2023-08-12 |
mouse |
| Reza Ardehali, Matthew A Inlay, Shah R Ali, Chad Tang, Micha Drukker, Irving L Weissma. Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 8. 2011-05-06. PMID:21300885. |
our data suggest that the bcl2 signaling pathway plays an important role in inhibiting hesc apoptosis, such that its overexpression in hescs offers both a survival benefit in conditions of stress by resisting apoptosis and obviates the requirement for serum or a feeder layer for maintenance. |
2011-05-06 |
2023-08-12 |
mouse |
| Debashree Mukherjea, Sarvesh Jajoo, Tejbeer Kaur, Kelly E Sheehan, Vickram Ramkumar, Leonard P Ryba. Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat. Antioxidants & redox signaling. vol 13. issue 5. 2011-04-22. PMID:20214492. |
also, transtympanic nox3 sirna reduced the expression of bax, abolished the decrease in expression of bcl2, and reduced apoptosis induced by cisplatin in the cochlea. |
2011-04-22 |
2023-08-12 |
rat |
| Zhigang Bai, Yingjiang Ye, Bin Liang, Feng Xu, Hui Zhang, Yanbin Zhang, Jiarou Peng, Danhua Shen, Zhirong Cui, Zhongtao Zhang, Shan Wan. Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer. International journal of oncology. vol 38. issue 2. 2011-04-19. PMID:21165559. |
the identified proteins were functionally classified using bioinformatics methods, showing that the 9 proteins identified were related to bcl2, bax, erbb2 and casp3 proteins and involved in the process of apoptosis. |
2011-04-19 |
2023-08-12 |
Not clear |
| Manujendra N Saha, Hua Jiang, Hong Chan. Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways. Cancer biology & therapy. vol 10. issue 6. 2011-04-18. PMID:20595817. |
our data show that nutlin-induced apoptosis correlated with reduction in cell viability, upregulation of p53, p21 and mdm2 protein levels with a simultaneous increase in pro-apoptotic targets puma, bax and bak and downregulation of anti-apoptotic targets bcl2 and survivin and activation of caspase in mm cells harboring wild type p53. |
2011-04-18 |
2023-08-12 |
Not clear |
| Hengning Ke, Jennifer Y Zhang, Steven K Akiyama, John E Frenc. BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization. Cell adhesion & migration. vol 5. issue 1. 2011-04-18. PMID:20716950. |
in addition to its well-defined role as an antagonist in apoptosis, we propose that bcl2 may act as an intracellular suppressor of cell motility and adhesion under certain conditions. |
2011-04-18 |
2023-08-12 |
Not clear |
| Bhavya Balan Chandrika, Sathish Kumar Maney, Swathi U Lekshmi, Santhoshkumar Thankayyan Retnabha. Endoplasmic reticulum targeted Bcl2 confers long term cell survival through phosphorylation of heat shock protein 27. The international journal of biochemistry & cell biology. vol 42. issue 12. 2011-04-01. PMID:20800695. |
overexpression of anti-apoptotic bcl2 family proteins is often seen in cancers rendering them insensitive to apoptosis inducing anticancer strategies. |
2011-04-01 |
2023-08-12 |
Not clear |
| Bhavya Balan Chandrika, Sathish Kumar Maney, Swathi U Lekshmi, Santhoshkumar Thankayyan Retnabha. Endoplasmic reticulum targeted Bcl2 confers long term cell survival through phosphorylation of heat shock protein 27. The international journal of biochemistry & cell biology. vol 42. issue 12. 2011-04-01. PMID:20800695. |
the results suggest that bcl2 possess additional survival function in the regulation of apoptosis which is primarily regulated by its association with the er in an hsp27 dependent manner. |
2011-04-01 |
2023-08-12 |
Not clear |
| Sheila J Semaan, Robert W Nickell. The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein. BMC cancer. vol 10. 2011-03-21. PMID:20942963. |
intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that is controlled by proteins of the bcl2 gene family. |
2011-03-21 |
2023-08-12 |
Not clear |
| Sheila J Semaan, Robert W Nickell. The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein. BMC cancer. vol 10. 2011-03-21. PMID:20942963. |
although stoichiometirc interactions between anti-apoptotic and bh3-only bcl2 family proteins have been well documented as affecting cell death, the association between changes in bax concentration and intrinsic apoptosis are poorly understood. |
2011-03-21 |
2023-08-12 |
Not clear |