| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea J French, Sekar Natesampillai, Ashton Krogman, Cristina Correia, Kevin L Peterson, Alecia Alto, Aswath P Chandrasekar, Anisha Misra, Ying Li, Scott H Kaufmann, Andrew D Badley, Nathan W Cummin. Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2. PLoS pathogens. vol 16. issue 10. 2021-01-07. PMID:33075109. |
reactivating latent hiv with pkc agonists induces resistance to apoptosis and is associated with phosphorylation and activation of bcl2. |
2021-01-07 |
2023-08-13 |
Not clear |
| Andrea J French, Sekar Natesampillai, Ashton Krogman, Cristina Correia, Kevin L Peterson, Alecia Alto, Aswath P Chandrasekar, Anisha Misra, Ying Li, Scott H Kaufmann, Andrew D Badley, Nathan W Cummin. Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2. PLoS pathogens. vol 16. issue 10. 2021-01-07. PMID:33075109. |
protein kinase c (pkc) agonists bryostatin-1 and prostratin induced phosphorylation and enhanced neutralizing capability of the anti-apoptotic protein bcl2 in a pkc-dependent manner, leading to resistance to apoptosis induced by both intrinsic and extrinsic death stimuli. |
2021-01-07 |
2023-08-13 |
Not clear |
| Zhong Yong Qin, Xiao Shi, Ping Ping Cao, Ying Chu, Wei Guan, Nan Yang, He Cheng, Yu Jie Su. [The NOXA promoter could function as an active enhancer to regulate the expression of BCL2 in the apoptosis response]. Yi chuan = Hereditas. vol 42. issue 11. 2021-01-06. PMID:33229317. |
[the noxa promoter could function as an active enhancer to regulate the expression of bcl2 in the apoptosis response]. |
2021-01-06 |
2023-08-13 |
Not clear |
| Zhong Yong Qin, Xiao Shi, Ping Ping Cao, Ying Chu, Wei Guan, Nan Yang, He Cheng, Yu Jie Su. [The NOXA promoter could function as an active enhancer to regulate the expression of BCL2 in the apoptosis response]. Yi chuan = Hereditas. vol 42. issue 11. 2021-01-06. PMID:33229317. |
based on the apoptosis model of mcf-7 cells induced by camptothecin, we used chromosome conformation capture (3c), quantitative real-time pcr (qrt-pcr) and the luciferase reporter gene technology to demonstrate that the noxa promoter could function as an active enhancer and physically interact with the bcl2 promoter through chromatin looping. |
2021-01-06 |
2023-08-13 |
Not clear |
| Zhong Yong Qin, Xiao Shi, Ping Ping Cao, Ying Chu, Wei Guan, Nan Yang, He Cheng, Yu Jie Su. [The NOXA promoter could function as an active enhancer to regulate the expression of BCL2 in the apoptosis response]. Yi chuan = Hereditas. vol 42. issue 11. 2021-01-06. PMID:33229317. |
this study provides new clues for further exploring the mechanism underlying cooperative response of bcl2 family member to apoptosis stimuli. |
2021-01-06 |
2023-08-13 |
Not clear |
| Li-Yun Fann, Jui-Hu Shih, Jen-Ho Tseng, Hsu-Shan Huang, Sheng-Huang Hsia. CC12 Induces Apoptotic Cell Death and Cell Cycle Arrest in Human Glioblastoma Cell Lines and Mouse Xenograft Model. Molecules (Basel, Switzerland). vol 25. issue 8. 2021-01-04. PMID:32295275. |
increased γh2ax, caspase-3, and poly (adp-ribose) polymerase (parp) levels meant the dna damage, and increased bcl2 family proteins after cc12 treatment indicated the intrinsic apoptotic pathway was involved in cc12 induced apoptosis. |
2021-01-04 |
2023-08-13 |
mouse |
| Mahesh Tambe, Ella Karjalainen, Markus Vähä-Koskela, Daria Bulanova, Bjørn T Gjertsen, Mika Kontro, Kimmo Porkka, Caroline A Heckman, Krister Wennerber. Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition. Leukemia. vol 34. issue 12. 2021-01-04. PMID:32651543. |
pan-raf inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with bcl2 inhibition. |
2021-01-04 |
2023-08-13 |
Not clear |
| Krzysztof Jan Witek, Adam J Ziecik, Izabela Małysz-Cymborska, Aneta Andronowsk. The presence of CC chemokines and their aberrant role in the porcine corpus luteum. Reproduction in domestic animals = Zuchthygiene. vol 55. issue 5. 2020-12-21. PMID:32119150. |
ccl2 treatment alone upregulated the expression of genes bax, bcl2 and star in cl cells in vitro, but additional experiments showed that the chemokines ccl2, ccl4 and ccl5 alone do not cause apoptosis in a mixed population of cl cells. |
2020-12-21 |
2023-08-13 |
Not clear |
| Yangyang Jiang, Bing Fang, Bin Xu, Liang Che. The RAS-PI3K-AKT-NF-κB pathway transcriptionally regulates the expression of BCL2 family and IAP family genes and inhibits apoptosis in fibrous epulis. Journal of clinical laboratory analysis. vol 34. issue 3. 2020-12-17. PMID:31743516. |
the ras-pi3k-akt-nf-κb pathway transcriptionally regulates the expression of bcl2 family and iap family genes and inhibits apoptosis in fibrous epulis. |
2020-12-17 |
2023-08-13 |
Not clear |
| Qiang Zhang, Yongchang Miao, Qingsheng Fu, Hao Hu, Hao Chen, Ailiang Zeng, Yan Jin, Yangfan Jiang, Long Qian, Longchao Wu, Li Xu, Gang Wang, Lei Qiu, Xiaoxu Huang, Yabin Xi. CircRNACCDC66 regulates cisplatin resistance in gastric cancer via the miR-618/BCL2 axis. Biochemical and biophysical research communications. vol 526. issue 3. 2020-12-17. PMID:32253030. |
data from in vitro and vivo experiments demonstrated that circccdc66 inhibited apoptosis by targeting mir-618 and release of b-cell lymphoma-2 (bcl2). |
2020-12-17 |
2023-08-13 |
human |
| Arnab Banerjee, Debasmita Das, Rajarshi Paul, Sandipan Roy, Ujjal Das, Samrat Saha, Sanjit Dey, Arghya Adhikary, Sandip Mukherjee, Bithin Kumar Maj. Mechanistic study of attenuation of monosodium glutamate mixed high lipid diet induced systemic damage in rats by Coccinia grandis. Scientific reports. vol 10. issue 1. 2020-12-15. PMID:32963259. |
furthermore, eecgl significantly inhibited hm-induced increased population of cells in sub g0/g1 phase, decreased bcl2 expression and thereby loss of mitochondrial membrane potential with over expression of bax, p53, p21, activation of caspase 3 and 9 indicated the apoptosis and suppression of cell survival. |
2020-12-15 |
2023-08-13 |
rat |
| Arjun Sharma, Pravir Kumar, Rashmi K Ambast. Cancer Fighting SiRNA-RRM2 Loaded Nanorobots. Pharmaceutical nanotechnology. vol 8. issue 2. 2020-12-14. PMID:32003677. |
the knockdown of rrm2 leads to apoptosis via bcl2 in cancer. |
2020-12-14 |
2023-08-13 |
Not clear |
| Kinga Szymona, Ewa Dudzińska, Hanna Karakuła-Juchnowicz, Paulina Gil-Kulik, Piotr Chomik, Małgorzata Świstowska, Joanna Gałaszkiewicz, Janusz Kock. Analysis of the expression of BAX, BCL2, BIRC6, CASP3, CASP9 apoptosis genes during the first episode of schizophrenia. Psychiatria polska. vol 53. issue 6. 2020-12-10. PMID:32017818. |
analysis of the expression of bax, bcl2, birc6, casp3, casp9 apoptosis genes during the first episode of schizophrenia. |
2020-12-10 |
2023-08-13 |
Not clear |
| Kinga Szymona, Ewa Dudzińska, Hanna Karakuła-Juchnowicz, Paulina Gil-Kulik, Piotr Chomik, Małgorzata Świstowska, Joanna Gałaszkiewicz, Janusz Kock. Analysis of the expression of BAX, BCL2, BIRC6, CASP3, CASP9 apoptosis genes during the first episode of schizophrenia. Psychiatria polska. vol 53. issue 6. 2020-12-10. PMID:32017818. |
the aim of the study was the analysis of (1) the level of bax,bcl2,birc6,casp3, casp9 apoptosis genes expression in schizophrenic patients and in the control group, and (2) the relationships between the genes expression level and the morphological and biochemical parameters, as well as the severity of psychopathological symptoms. |
2020-12-10 |
2023-08-13 |
Not clear |
| Maria Jesús García-Murria, Gerard Duart, Brayan Grau, Elisabet Diaz-Beneitez, Dolores Rodríguez, Ismael Mingarro, Luis Martínez-Gi. Viral Bcl2s' transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis. Nature communications. vol 11. issue 1. 2020-12-09. PMID:33247105. |
viral bcl2s' transmembrane domain interact with host bcl2 proteins to control cellular apoptosis. |
2020-12-09 |
2023-08-13 |
Not clear |
| Maria Jesús García-Murria, Gerard Duart, Brayan Grau, Elisabet Diaz-Beneitez, Dolores Rodríguez, Ismael Mingarro, Luis Martínez-Gi. Viral Bcl2s' transmembrane domain interact with host Bcl2 proteins to control cellular apoptosis. Nature communications. vol 11. issue 1. 2020-12-09. PMID:33247105. |
vbcl2s control apoptosis by interacting with host pro- and anti-apoptotic members of the bcl2 family. |
2020-12-09 |
2023-08-13 |
Not clear |
| Stefania Bottardi, Romain Guieze, Vincent Bourgoin, Nasser Fotouhi-Ardakani, Aurore Dougé, Anaïs Darracq, Yahia A Lakehal, Marc G Berger, Luigina Mollica, Jacques-Olivier Bay, James G Omichinski, Eric Milo. MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells. Experimental hematology. vol 88. 2020-12-08. PMID:32682001. |
we propose that this rapid dynamic tuning of rna levels, which leads to the destabilization of mcl1 and bcl2 transcripts, represents a post-transcriptional mechanism of apoptosis control in cll cells. |
2020-12-08 |
2023-08-13 |
human |
| Jacob T Jackson, Kristy O'Donnell, Amanda Light, Wilford Goh, Nicholas D Huntington, David M Tarlinton, Matthew P McCormac. Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a. European journal of immunology. vol 50. issue 7. 2020-12-07. PMID:32090320. |
as loss of hhex causes apoptosis of lymphoid progenitors associated with impaired bcl2 expression and defective stat5b signaling, we tested the effects of rescuing these pathways using transgenic mice. |
2020-12-07 |
2023-08-13 |
mouse |
| Ling Chen, Qingxiang Hou, Li Feng, Ling Li Xin, Li M. Inhibitory and protective effect of obovatol against uterine fibroid (leiomyoma) cells. Pakistan journal of pharmaceutical sciences. vol 33. issue 1(Supplementary). 2020-12-04. PMID:32122859. |
in addition, apoptosis regulatory proteins like bcl2 and bax were substantially down and up-regulated respectively, by ob in a dose-dependent fashion. |
2020-12-04 |
2023-08-13 |
human |
| Baoyuan Jin, Hyehyun Kim, Jeong-Il Choi, Hong-Beom Bae, Seongtae Jeon. Avenanthramide C Prevents Neuronal Apoptosis via PI3K/Akt/GSK3β Signaling Pathway Following Middle Cerebral Artery Occlusion. Brain sciences. vol 10. issue 11. 2020-12-01. PMID:33233587. |
we evaluated the blood brain barrier (bbb) integrity (zo-1, ve-cadherin and occludin) and apoptosis (bax, bcl2, caspase3, cytochrome c, and poly adp ribose polymerase(parp)-1). |
2020-12-01 |
2023-08-13 |
mouse |