| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Wang, Liming Zhu, Mei Guo, Gang Sun, Kun Zhou, Wenjing Pang, Dachun Cao, Xin Tang, Xiangjun Men. Correction to: Histone methyltransferase WHSC1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic BCL2. Cell death discovery. vol 7. issue 1. 2021-10-26. PMID:34675194. |
correction to: histone methyltransferase whsc1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic bcl2. |
2021-10-26 |
2023-08-13 |
Not clear |
| Hamad Mohammed AbuZahra, Peramaiyan Rajendran, Mohammad Bani Ismai. Zerumbone Exhibit Protective Effect against Zearalenone Induced Toxicity via Ameliorating Inflammation and Oxidative Stress Induced Apoptosis. Antioxidants (Basel, Switzerland). vol 10. issue 10. 2021-10-26. PMID:34679730. |
furthermore, zer increasingly activated bcl2 and suppressed apoptosis marker proteins. |
2021-10-26 |
2023-08-13 |
mouse |
| Yu Feng, Hantao Wang, Zhi Chen, Bin Che. High glucose mediates the ChREBP/p300 transcriptional complex to activate proapoptotic genes Puma and BAX and contributes to intervertebral disc degeneration. Bone. vol 153. 2021-10-25. PMID:34461288. |
using a microarray assay to detect the dysregulated genes in idd patients with obesity, we identified 33 differentially expressed genes and verified only two proapoptotic genes, including puma (p53 upregulated modulator of apoptosis) and bax (bcl2 associated x) responded to glucose. |
2021-10-25 |
2023-08-13 |
rat |
| Yu Wang, Liming Zhu, Mei Guo, Gang Sun, Kun Zhou, Wenjing Pang, Dachun Cao, Xin Tang, Xiangjun Men. Histone methyltransferase WHSC1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic BCL2. Cell death discovery. vol 7. issue 1. 2021-10-23. PMID:33469000. |
histone methyltransferase whsc1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic bcl2. |
2021-10-23 |
2023-08-13 |
Not clear |
| Jacky Bhagat, Liqing Zang, Hiroko Nakayama, Norihiro Nishimura, Yasuhito Shimad. Effects of nanoplastic on toxicity of azole fungicides (ketoconazole and fluconazole) in zebrafish embryos. The Science of the total environment. vol 800. 2021-10-22. PMID:34399343. |
we investigated the effects of polystyrene (ps) np on the toxicity of ketoconazole (kcz) and fluconazole (fcz) in zebrafish embryos using the developmental toxicity, oxidative-stress-related biochemical parameters, and expression of genes related to neurotoxicity (ache), cardiotoxicity (gata4, bmp4), inflammation (il1b), oxidative stress (sod1, sod2, cyp1a), and apoptosis (bax, bcl2). |
2021-10-22 |
2023-08-13 |
zebrafish |
| Yan Li, Xiaolin Zhang, Yuanyuan Wei, Shujuan Wen, Xing Lin, Quanfang Huan. [Tormentic acid inhibits proliferation and promotes apoptosis of LX-2 human hepatic stellate cells via blocking NF-κB signaling pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 37. issue 10. 2021-10-22. PMID:34670666. |
ta significantly induced lx-2 cells apoptosis by down-regulating the expression of the anti-apoptotic protein bcl2 and up-regulating the expression of the pro-apoptotic protein bax. |
2021-10-22 |
2023-08-13 |
human |
| Robert G Hawley, Yuzhong Chen, Irene Riz, Chen Zen. An Integrated Bioinformatics and Computational Biology Approach Identifies New BH3-Only Protein Candidates. The open biology journal. vol 5. 2021-10-21. PMID:22754595. |
in particular, the analysis strongly suggests that the apoptosis inhibitor and dna damage response regulator, aven, which was originally isolated as a bcl-xl-interacting protein, is a functional bh3-only protein representing a distinct subclass of bcl2 family members. |
2021-10-21 |
2023-08-12 |
Not clear |
| Aruna Basu, Xin Jiang, Massimo Negrini, Subrata Halda. MicroRNA-mediated regulation of pancreatic cancer cell proliferation. Oncology letters. vol 1. issue 3. 2021-10-21. PMID:22966344. |
the overall objective of our investigation was to assess whether mirna-16 (mir-16) is involved in the regulation of critical genes, such as bcl2, that control the sensitivity of pancreatic cancer cells to apoptosis. |
2021-10-21 |
2023-08-12 |
human |
| Yangjun Gao, Hong Wu, Dongmei He, Xiaomao Hu, Yangqiu L. Downregulation of BCL11A by siRNA induces apoptosis in B lymphoma cell lines. Biomedical reports. vol 1. issue 1. 2021-10-21. PMID:24648892. |
in this study, we investigated whether the downregulation of bcl11a mrna by small interference rna (sirna) was capable of inducing apoptosis, and tested the effect of bcl11a sirna combined with bcl2 sirna in b lymphoma cell lines (sudhl6, eb1). |
2021-10-21 |
2023-08-12 |
Not clear |
| Yangjun Gao, Hong Wu, Dongmei He, Xiaomao Hu, Yangqiu L. Downregulation of BCL11A by siRNA induces apoptosis in B lymphoma cell lines. Biomedical reports. vol 1. issue 1. 2021-10-21. PMID:24648892. |
moreover, bcl11a sirna combined with bcl2 sirna increased apoptosis in sudhl6, eb1 cells. |
2021-10-21 |
2023-08-12 |
Not clear |
| Meng Song, Xueping Ou, Cuicui Xiao, Zhongming Xiao, Fang Wei, Yan Hon. Hedgehog signaling inhibitor cyclopamine induces apoptosis by decreasing Gli2 and Bcl2 expression in human salivary pleomorphic adenoma cells. Biomedical reports. vol 1. issue 2. 2021-10-21. PMID:24648943. |
hedgehog signaling inhibitor cyclopamine induces apoptosis by decreasing gli2 and bcl2 expression in human salivary pleomorphic adenoma cells. |
2021-10-21 |
2023-08-12 |
human |
| Meng Song, Xueping Ou, Cuicui Xiao, Zhongming Xiao, Fang Wei, Yan Hon. Hedgehog signaling inhibitor cyclopamine induces apoptosis by decreasing Gli2 and Bcl2 expression in human salivary pleomorphic adenoma cells. Biomedical reports. vol 1. issue 2. 2021-10-21. PMID:24648943. |
the aim of this study was to investigate the effect of cyclopamine induction apoptosis in human salivary pleomorphic adenoma (hspa) cells and the impact on gli2 and bcl2 mrna levels. |
2021-10-21 |
2023-08-12 |
human |
| Mahnoush Kolahdouz, Faranak Jafari, Farahnaz Falanji, Samad Nazemi, Mohammad Mohammadzadeh, Mehdi Molavi, Bahareh Ami. Clavulanic Acid Attenuating Effect on the Diabetic Neuropathic Pain in Rats. Neurochemical research. vol 46. issue 7. 2021-10-18. PMID:33846883. |
the expression of the glutamate transport 1 (glt1), genes of oxidative stress including inducible nitric oxide synthase (inos), proinflammatory cytokine, tumor necrosis factor alpha (tnf-α), as well as genes involved in the apoptosis including bcl2, bcl2-associated x (bax) were measured in the spinal cord tissue by real time pcr, on day 42. |
2021-10-18 |
2023-08-13 |
rat |
| Bin Xu, Shu-Cheng Zang, Li-Min Lang, Shuai Lian, Jingjing Lu, Shi-Ze Li, Huan-Min Yang, Li Zhe. Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2. Journal of animal physiology and animal nutrition. vol 104. issue 6. 2021-10-15. PMID:32090391. |
down-regulation of mir-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting bcl2. |
2021-10-15 |
2023-08-13 |
rat |
| Milirani Das, Lalrawngbawli Annie, Kira V Derkach, Alexander O Shpakov, Guruswami Gurusubramanian, Vikas Kumar Ro. Expression and localization of apelin and its receptor in the testes of diabetic mice and its possible role in steroidogenesis. Cytokine. vol 144. 2021-10-15. PMID:33962842. |
the diabetic testes had a decrease in germ cell proliferation (the reduced pcna and gcna levels) and an increase in apoptosis (the increased active caspase-3 and decreased bcl2 levels). |
2021-10-15 |
2023-08-13 |
mouse |
| Jie Shi, Shaoyi Wang, Qiting He, Kaiwen Liu, Wei Zhao, Qing Xie, Lei Chen. TNF-α induces up-regulation of MicroRNA-27a via the P38 signalling pathway, which inhibits intervertebral disc degeneration by targeting FSTL1. Journal of cellular and molecular medicine. vol 25. issue 15. 2021-10-15. PMID:34190406. |
apoptosis of nucleus pulposus cells was detected by flow cytometry and bcl2, bax and caspase 3. |
2021-10-15 |
2023-08-13 |
human |
| Hai-Fan Yu, Lian-Wen Zheng, Zhan-Qing Yang, Yu-Si Wang, Ting-Ting Wang, Zhan-Peng Yue, Bin Gu. TAZ as a novel regulator of oxidative damage in decidualization via Nrf2/ARE/Foxo1 pathway. Experimental & molecular medicine. vol 53. issue 9. 2021-10-15. PMID:34497345. |
moreover, taz prevented stromal cell apoptosis by upregulating bcl2 expression and inhibiting casp3 activity and bax expression. |
2021-10-15 |
2023-08-13 |
Not clear |
| Hui Bai, Tingting Li, Yan Yu, Ningcong Zhou, Huijuan Kou, Yingying Guo, Liang Yang, Peishi Ya. Cytoprotective Effects of Taurine on Heat-Induced Bovine Mammary Epithelial Cells In Vitro. Cells. vol 10. issue 2. 2021-10-14. PMID:33525569. |
taurine also alleviated the rates of cell apoptosis and markedly depressed the mrna expressions of bcl2 associated x, apoptosis regulator (bax) and caspase3. |
2021-10-14 |
2023-08-13 |
cattle |
| Chien-Yu Huang, Yu-Jia Chang, Po-Li Wei, Chin-Sheng Hung, Weu Wan. Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells. PloS one. vol 16. issue 3. 2021-10-13. PMID:33725002. |
the western blot analysis showed that mg activated cleavage of caspase-3 and poly (sdp ribose) polymerase (parp), modulated levels of the bcl2, bax, and bad ligands, and induced apoptosis. |
2021-10-13 |
2023-08-13 |
human |
| Ayan Mondal, Punnag Saha, Dipro Bose, Somdatta Chatterjee, Ratanesh K Seth, Shuo Xiao, Dwayne E Porter, Bryan W Brooks, Geoff I Scott, Mitzi Nagarkatti, Prakash Nagarkatti, Saurabh Chatterje. Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. Toxicology. vol 461. 2021-10-13. PMID:34416350. |
mechanistically, conditioned medium from reactive astrocytes and parallel s100b incubation in neuronal cells caused increased inducible nos, cox-2, and higher bax/ bcl2 protein expression suggesting oxidative stress-mediated neuronal cell apoptosis crucial for neurodegeneration. |
2021-10-13 |
2023-08-13 |
mouse |