| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L A Kroger, G L DeNardo, P H Gumerlock, C Y Xiong, M D Winthrop, X B Shi, P C Mack, T Leshchinsky, S J DeNard. Apoptosis-related gene and protein expression in human lymphoma xenografts (Raji) after low dose rate radiation using 67Cu-2IT-BAT-Lym-1 radioimmunotherapy. Cancer biotherapy & radiopharmaceuticals. vol 16. issue 3. 2001-12-18. PMID:11471486. |
subgroups of 4-5 mice were sacrificed at 3, 6 and 24 h after therapy so that tumors could be examined for poly(adp-ribose) polymerase (parp) and dna ladder evidence for apoptosis and for bcl2, p53, p21, gadd45, tgf-beta 1 and c-myc gene and protein expression. |
2001-12-18 |
2023-08-12 |
mouse |
| P Farid, S Z Gomb, I Péter, B Szend. bcl2, p53 and bax in thyroid tumors and their relation to apoptosis. Neoplasma. vol 48. issue 4. 2001-12-10. PMID:11712682. |
bcl2, p53 and bax in thyroid tumors and their relation to apoptosis. |
2001-12-10 |
2023-08-12 |
Not clear |
| P Farid, S Z Gomb, I Péter, B Szend. bcl2, p53 and bax in thyroid tumors and their relation to apoptosis. Neoplasma. vol 48. issue 4. 2001-12-10. PMID:11712682. |
twenty five thyroid tumors were investigated by immunohistochemistry for the presence of apoptosis, expression of p53, bax and bcl2. |
2001-12-10 |
2023-08-12 |
Not clear |
| G Guasch, V Ollendorff, J P Borg, D Birnbaum, M J Pébusqu. 8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways. Molecular and cellular biology. vol 21. issue 23. 2001-12-05. PMID:11689702. |
finally, fop-fgfr1 protects cells from apoptosis by survival signals including bcl2 overexpression and inactivation of caspase-9 activity. |
2001-12-05 |
2023-08-12 |
Not clear |
| R J Bold, S Virudachalam, D J McConke. BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines. Cancer. vol 92. issue 5. 2001-10-04. PMID:11571724. |
dysregulation in the expression of the bcl2 gene family, the prototypic regulators of apoptosis, is a common occurrence in cancer and imparts resistance to standard triggers of apoptosis. |
2001-10-04 |
2023-08-12 |
Not clear |
| R J Bold, S Virudachalam, D J McConke. BCL2 expression correlates with metastatic potential in pancreatic cancer cell lines. Cancer. vol 92. issue 5. 2001-10-04. PMID:11571724. |
therefore, the authors sought to examine whether abnormal bcl2 gene family expression correlated with resistance to apoptosis and increased metastatic potential in pancreatic carcinoma. |
2001-10-04 |
2023-08-12 |
Not clear |
| I Contasta, P Pellegrini, A M Berghella, D Adorn. Cell cycle control in cellular homeostasis during the immune response: interactions between TH1, TH2 cytokines, and Bcl2 and p53 molecules. Cancer biotherapy & radiopharmaceuticals. vol 16. issue 1. 2001-09-13. PMID:11279799. |
expression of the bcl2 gene promotes cell survival by countering apoptosis stimuli. |
2001-09-13 |
2023-08-12 |
human |
| S J George, G D Angelini, M C Capogrossi, A H Bake. Wild-type p53 gene transfer inhibits neointima formation in human saphenous vein by modulation of smooth muscle cell migration and induction of apoptosis. Gene therapy. vol 8. issue 9. 2001-08-02. PMID:11406761. |
initial in vitro analyses demonstrated that wt p53 overexpression had no effect on smc proliferation but promoted apoptosis, which was inhibited by co-expression of bcl2 or crma. |
2001-08-02 |
2023-08-12 |
human |
| Z Dastoor, J L Dreye. Potential role of nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in apoptosis and oxidative stress. Journal of cell science. vol 114. issue Pt 9. 2001-07-26. PMID:11309196. |
bcl2 overexpression prevents nuclear translocation of gapdh and apoptosis in untransfected cells, but not in transfected cells that overexpress gapdh-gfp. |
2001-07-26 |
2023-08-12 |
Not clear |
| S Meintières, A Biola, M Pallardy, D Marzi. Apoptosis can be a confusing factor in in vitro clastogenic assays. Mutagenesis. vol 16. issue 3. 2001-07-26. PMID:11320150. |
we used a murine cytotoxic t cell line, ctll-2 bcl2, in which a stably transfected bcl2 gene is known to protect these cells from apoptosis induced by various stimuli. |
2001-07-26 |
2023-08-12 |
Not clear |
| S Meintières, A Biola, M Pallardy, D Marzi. Apoptosis can be a confusing factor in in vitro clastogenic assays. Mutagenesis. vol 16. issue 3. 2001-07-26. PMID:11320150. |
a comparison between results obtained in parental ctll-2 cells and in ctll-2 bcl2 cells treated with non-genotoxic apoptosis inducers, such as dexamethasone or gliotoxin, leads us to conclude that apoptosis could give false positive results due to dna fragmentation. |
2001-07-26 |
2023-08-12 |
Not clear |
| S Meintières, A Biola, M Pallardy, D Marzi. Apoptosis can be a confusing factor in in vitro clastogenic assays. Mutagenesis. vol 16. issue 3. 2001-07-26. PMID:11320150. |
moreover, with etoposide, a clastogen that also induces apoptosis, we observed that the percentages of aberrant cells and numbers of micronuclei were significantly increased in ctll-2 cells compared with ctll-2 bcl2 cells. |
2001-07-26 |
2023-08-12 |
Not clear |
| S H Lee, J G Choi, M H Ch. Apoptosis, bcl2 expression, and cell cycle analyses in nickel(II)-treated normal rat kidney cells. Journal of Korean medical science. vol 16. issue 2. 2001-07-19. PMID:11306741. |
apoptosis, bcl2 expression, and cell cycle analyses in nickel(ii)-treated normal rat kidney cells. |
2001-07-19 |
2023-08-12 |
human |
| S H Lee, J G Choi, M H Ch. Apoptosis, bcl2 expression, and cell cycle analyses in nickel(II)-treated normal rat kidney cells. Journal of Korean medical science. vol 16. issue 2. 2001-07-19. PMID:11306741. |
in this study, the effects of nickel(ii) acetate on apoptosis, cell cycle and bcl2 expression in normal rat kidney (nrk- 52e) cells were investigated. |
2001-07-19 |
2023-08-12 |
human |
| D B Pateder, R A Eliseev, R J O'Keefe, E M Schwarz, P Okunieff, L S Constine, J E Puzas, R N Rosie. The role of autocrine growth factors in radiation damage to the epiphyseal growth plate. Radiation research. vol 155. issue 6. 2001-06-21. PMID:11352768. |
since pthrp up-regulates bcl2 levels and prevents growth plate chondrocyte maturation and apoptosis, bcl2 mrna levels were examined in irradiated growth plate chondrocytes, and a dose-dependent decrease was found. |
2001-06-21 |
2023-08-12 |
chicken |
| P P Ruvolo, X Deng, W S Ma. Phosphorylation of Bcl2 and regulation of apoptosis. Leukemia. vol 15. issue 4. 2001-05-31. PMID:11368354. |
phosphorylation of bcl2 and regulation of apoptosis. |
2001-05-31 |
2023-08-12 |
Not clear |
| P P Ruvolo, X Deng, W S Ma. Phosphorylation of Bcl2 and regulation of apoptosis. Leukemia. vol 15. issue 4. 2001-05-31. PMID:11368354. |
members of the bcl2 family of proteins are important regulators of programmed cell death pathways with individual members that can suppress (eg bcl2, bcl-xl) or promote (eg bax, bad) apoptosis. |
2001-05-31 |
2023-08-12 |
Not clear |
| P P Ruvolo, X Deng, W S Ma. Phosphorylation of Bcl2 and regulation of apoptosis. Leukemia. vol 15. issue 4. 2001-05-31. PMID:11368354. |
there are, however, physiologic situations in which bcl2 expression apparently fails to protect cells from apoptosis (eg negative selection of thymocytes). |
2001-05-31 |
2023-08-12 |
Not clear |
| P P Ruvolo, X Deng, W S Ma. Phosphorylation of Bcl2 and regulation of apoptosis. Leukemia. vol 15. issue 4. 2001-05-31. PMID:11368354. |
these findings indicate that simple expression of bcl2 may not be enough to functionally protect cells from apoptosis. |
2001-05-31 |
2023-08-12 |
Not clear |
| S Cho, J H Hahm, Y S Hon. Analysis of p53 and BAX mutations, loss of heterozygosity, p53 and BCL2 expression and apoptosis in basal cell carcinoma in Korean patients. The British journal of dermatology. vol 144. issue 4. 2001-05-24. PMID:11298546. |
analysis of p53 and bax mutations, loss of heterozygosity, p53 and bcl2 expression and apoptosis in basal cell carcinoma in korean patients. |
2001-05-24 |
2023-08-12 |
Not clear |