| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Grazia D'Onofrio, Francesco Panza, Davide Seripa, Daniele Sancarlo, Francesco Paris, Leandro Cascavilla, Maria Urbano, Carolina Gravina, Andrea Fontana, Vincenzo Solfrizzi, Fabio Pellegrini, Alberto Pilott. The APOE polymorphism in Alzheimer's disease patients with neuropsychiatric symptoms and syndromes. International journal of geriatric psychiatry. vol 26. issue 10. 2011-12-21. PMID:21905100. |
the apoe polymorphism in alzheimer's disease patients with neuropsychiatric symptoms and syndromes. |
2011-12-21 |
2023-08-12 |
Not clear |
| Po H Lu, Paul M Thompson, Alex Leow, Grace J Lee, Agatha Lee, Igor Yanovsky, Neelroop Parikshak, Theresa Khoo, Stephanie Wu, Daniel Geschwind, George Bartzoki. Apolipoprotein E genotype is associated with temporal and hippocampal atrophy rates in healthy elderly adults: a tensor-based morphometry study. Journal of Alzheimer's disease : JAD. vol 23. issue 3. 2011-12-20. PMID:21098974. |
apolipoprotein e (apoe) ε4 genotype is a strong risk factor for developing alzheimer's disease (ad). |
2011-12-20 |
2023-08-12 |
human |
| Lina Keller, Weili Xu, Hui-Xin Wang, Bengt Winblad, Laura Fratiglioni, Caroline Graf. The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study. Journal of Alzheimer's disease : JAD. vol 23. issue 3. 2011-12-20. PMID:21098976. |
the obesity related gene, fto, interacts with apoe, and is associated with alzheimer's disease risk: a prospective cohort study. |
2011-12-20 |
2023-08-12 |
human |
| C Conejero-Goldberg, T M Hyde, S Chen, U Dreses-Werringloer, M M Herman, J E Kleinman, P Davies, T E Goldber. Molecular signatures in post-mortem brain tissue of younger individuals at high risk for Alzheimer's disease as based on APOE genotype. Molecular psychiatry. vol 16. issue 8. 2011-12-19. PMID:20479757. |
molecular signatures in post-mortem brain tissue of younger individuals at high risk for alzheimer's disease as based on apoe genotype. |
2011-12-19 |
2023-08-12 |
Not clear |
| Julie E Simpson, Paul G Ince, Pamela J Shaw, Paul R Heath, Rohini Raman, Claire J Garwood, Catherine Gelsthorpe, Lynne Baxter, Gillian Forster, Fiona E Matthews, Carol Brayne, Stephen B Wharto. Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype. Neurobiology of aging. vol 32. issue 10. 2011-12-15. PMID:21705112. |
microarray analysis of the astrocyte transcriptome in the aging brain: relationship to alzheimer's pathology and apoe genotype. |
2011-12-15 |
2023-08-12 |
Not clear |
| Gabriele Frank, Kristina Hennig-Fast, Hans H Klünemann, Gerd Schmitz, Mark W Greenle. Differential impact of ApoE ε4 on cortical activation during famous face recognition in cognitively intact individuals and patients with amnestic mild cognitive impairment. Alzheimer disease and associated disorders. vol 25. issue 3. 2011-12-14. PMID:21192235. |
our results show that critical regions of the brain show functional decline associated with major risk factors, such as apoe ε4 allele and neuropsychological signs of amci for the development of alzheimer disease. |
2011-12-14 |
2023-08-12 |
human |
| Kaijuan Guo, Xiaohong Li, Heinz-Bernhard Kraat. Exploiting the interactions of PNA-DNA films with Ni2+ ions: detection of nucleobase mismatches and electrochemical genotyping of the single-nucleotide mismatch in apoE 4 related to Alzheimer's disease. Biosensors & bioelectronics. vol 27. issue 1. 2011-12-07. PMID:21752624. |
exploiting the interactions of pna-dna films with ni2+ ions: detection of nucleobase mismatches and electrochemical genotyping of the single-nucleotide mismatch in apoe 4 related to alzheimer's disease. |
2011-12-07 |
2023-08-12 |
Not clear |
| Kaijuan Guo, Xiaohong Li, Heinz-Bernhard Kraat. Exploiting the interactions of PNA-DNA films with Ni2+ ions: detection of nucleobase mismatches and electrochemical genotyping of the single-nucleotide mismatch in apoE 4 related to Alzheimer's disease. Biosensors & bioelectronics. vol 27. issue 1. 2011-12-07. PMID:21752624. |
the approach works under real-life conditions with concentrations of the dna target strand down to 10 fm, and a pna capture probe is used to genotype the single-nucleotide mismatch in apoe 4 related to alzheimer's disease (ad). |
2011-12-07 |
2023-08-12 |
Not clear |
| Hongliang Zhang, Li-Min Wu, Jiang W. Cross-talk between apolipoprotein E and cytokines. Mediators of inflammation. vol 2011. 2011-12-06. PMID:21772670. |
despite its importance in lipid transport and atherosclerosis pathogenesis, apoe is associated with neurodegenerative disorders such as alzheimer's disease (ad) and parkinson disease, and autoimmune disorders such as multiple sclerosis and psoriasis. |
2011-12-06 |
2023-08-12 |
Not clear |
| Olga Calero, María J Bullido, Jordi Clarimón, Ana Frank-García, Pablo Martínez-Martín, Alberto Lleó, María Jesús Rey, Alberto Rábano, Rafael Blesa, Teresa Gómez-Isla, Fernando Valdivieso, Jesús de Pedro-Cuesta, Isidro Ferrer, Miguel Caler. Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases. PloS one. vol 6. issue 7. 2011-12-06. PMID:21799773. |
genetic cross-interaction between apoe and prnp in sporadic alzheimer's and creutzfeldt-jakob diseases. |
2011-12-06 |
2023-08-12 |
human |
| Bryan Maloney, Debomoy K Lahir. The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif. Gene. vol 488. issue 1-2. 2011-12-01. PMID:21699964. |
the alzheimer's amyloid β-peptide (aβ) binds a specific dna aβ-interacting domain (aβid) in the app, bace1, and apoe promoters in a sequence-specific manner: characterizing a new regulatory motif. |
2011-12-01 |
2023-08-12 |
Not clear |
| Hyman M Schippe. Presymptomatic apolipoprotein E genotyping for Alzheimer's disease risk assessment and prevention. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 7. issue 4. 2011-11-23. PMID:21665554. |
on the basis of emerging developments, in this article, we revisit the notion that presymptomatic apoe testing might be medically appropriate and ethical for the purpose of alzheimer's disease (ad) risk assessment and prevention. |
2011-11-23 |
2023-08-12 |
human |
| Sterling C Johnson, Asenath La Rue, Bruce P Hermann, Guofan Xu, Rebecca L Koscik, Erin M Jonaitis, Barbara B Bendlin, Kirk J Hogan, Allen D Roses, Ann M Saunders, Michael W Lutz, Sanjay Asthana, Robert C Green, Mark A Sage. The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 7. issue 4. 2011-11-23. PMID:21784354. |
apolipoprotein e (apoe) genotypes are associated with variable risk of developing late-onset alzheimer's disease (load), with apoe epsilon 4 (apoe ε4) having higher risk. |
2011-11-23 |
2023-08-12 |
Not clear |
| Avdesh Avdesh, Patrick Wong, Ralph N Martins, Mathew T Martin-Iverso. Memory function in a mouse genetic model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 25. issue 3. 2011-11-15. PMID:21460433. |
the e4 allele of the apolipoprotein e (apoe) gene has been identified as a major risk factor for the development of late onset alzheimer's disease (ad). |
2011-11-15 |
2023-08-12 |
mouse |
| Yadong Huan. Roles of apolipoprotein E4 (ApoE4) in the pathogenesis of Alzheimer's disease: lessons from ApoE mouse models. Biochemical Society transactions. vol 39. issue 4. 2011-11-15. PMID:21787325. |
roles of apolipoprotein e4 (apoe4) in the pathogenesis of alzheimer's disease: lessons from apoe mouse models. |
2011-11-15 |
2023-08-12 |
mouse |
| Christopher R Simmons, Fanggeng Zou, Steven G Younkin, Steven Estu. Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk. Molecular neurodegeneration. vol 6. 2011-11-10. PMID:21867541. |
since the alleles of the apoe gene, which modulate peripheral cholesterol metabolism, and midlife plasma cholesterol are both associated with alzheimer's disease (ad) risk, we have evaluated the hypothesis that snps associated with plasma cholesterol are also associated with ad. |
2011-11-10 |
2023-08-12 |
Not clear |
| Leon M Tai, Katherine L Youmans, Lisa Jungbauer, Chunjiang Yu, Mary Jo Lad. Introducing Human APOE into Aβ Transgenic Mouse Models. International journal of Alzheimer's disease. vol 2011. 2011-11-10. PMID:22028984. |
apolipoprotein e (apoe) and apoe/amyloid-β (aβ) transgenic (tg) mouse models are critical to understanding apoe-isoform effects on alzheimer's disease risk. |
2011-11-10 |
2023-08-12 |
mouse |
| Patricia Huebbe, Almut Nebel, Sabine Siegert, Jennifer Moehring, Christine Boesch-Saadatmandi, Erika Most, Josef Pallauf, Sarah Egert, Manfred James Müller, Stefan Schreiber, Ute Nöthlings, Gerald Rimbac. APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 25. issue 9. 2011-11-09. PMID:21659554. |
the allele ε4 of apolipoprotein e (apoe), which is a key regulator of lipid metabolism, represents a risk factor for cardiovascular diseases and alzheimer's disease. |
2011-11-09 |
2023-08-12 |
mouse |
| Loukia Katsouri, Spiros Georgopoulo. Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model. PloS one. vol 6. issue 7. 2011-11-09. PMID:21755005. |
apolipoprotein e (apoe), a cholesterol carrier associated with atherosclerosis, is a major risk factor for alzheimer's disease (ad). |
2011-11-09 |
2023-08-12 |
mouse |
| Ashok Patel, Simon D Rees, M Ann Kelly, Steven C Bain, Anthony H Barnett, Deepak Thalitaya, Vee P Prashe. Association of variants within APOE, SORL1, RUNX1, BACE1 and ALDH18A1 with dementia in Alzheimer's disease in subjects with Down syndrome. Neuroscience letters. vol 487. issue 2. 2011-11-08. PMID:20946940. |
association of variants within apoe, sorl1, runx1, bace1 and aldh18a1 with dementia in alzheimer's disease in subjects with down syndrome. |
2011-11-08 |
2023-08-12 |
human |