| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Whitson, M P Mims, W J Strittmatter, T Yamaki, J D Morrisett, S H Appe. Attenuation of the neurotoxic effect of A beta amyloid peptide by apolipoprotein E. Biochemical and biophysical research communications. vol 199. issue 1. 1994-04-01. PMID:8123007. |
thus, interaction between these proteins does not directly increase a beta neurotoxicity, and the role of apoe in alzheimer's disease remains to be elucidated. |
1994-04-01 |
2023-08-12 |
Not clear |
| M L Peacock, J K Fin. ApoE epsilon 4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis. Neurology. vol 44. issue 2. 1994-03-17. PMID:8309587. |
apoe epsilon 4 allelic association with alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis. |
1994-03-17 |
2023-08-12 |
human |
| M L Peacock, J K Fin. ApoE epsilon 4 allelic association with Alzheimer's disease: independent confirmation using denaturing gradient gel electrophoresis. Neurology. vol 44. issue 2. 1994-03-17. PMID:8309587. |
there is intriguing evidence associating apolipoprotein e (apoe) with alzheimer's disease (ad). |
1994-03-17 |
2023-08-12 |
human |
| J Hard. ApoE, amyloid, and Alzheimer's disease. Science (New York, N.Y.). vol 263. issue 5146. 1994-02-18. PMID:8290946. |
apoe, amyloid, and alzheimer's disease. |
1994-02-18 |
2023-08-12 |
Not clear |
| G W Rebeck, J S Reiter, D K Strickland, B T Hyma. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron. vol 11. issue 4. 1993-11-22. PMID:8398148. |
an increased prevalence of apolipoprotein e (apoe) epsilon 4 allele exists in late onset familial alzheimer's disease. |
1993-11-22 |
2023-08-12 |
Not clear |
| J Poirier, J Davignon, D Bouthillier, S Kogan, P Bertrand, S Gauthie. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet (London, England). vol 342. issue 8873. 1993-10-08. PMID:8103819. |
apolipoprotein e (apoe) is associated with alzheimer's neurofibrillary tangles and beta-amyloid protein in senile plaques. |
1993-10-08 |
2023-08-12 |
Not clear |
| J Poirier, J Davignon, D Bouthillier, S Kogan, P Bertrand, S Gauthie. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet (London, England). vol 342. issue 8873. 1993-10-08. PMID:8103819. |
the gene for apoe is on chromosome 19, within the genomic region previously associated with late-onset familial alzheimer's disease (ad). |
1993-10-08 |
2023-08-12 |
Not clear |
| W J Strittmatter, K H Weisgraber, D Y Huang, L M Dong, G S Salvesen, M Pericak-Vance, D Schmechel, A M Saunders, D Goldgaber, A D Rose. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 17. 1993-10-05. PMID:8367470. |
apolipoprotein e (apoe), a plasma apolipoprotein that plays a central role in lipoprotein metabolism, is localized in the senile plaques, congophilic angiopathy, and neurofibrillary tangles of alzheimer disease. |
1993-10-05 |
2023-08-12 |
human |
| W J Strittmatter, K H Weisgraber, D Y Huang, L M Dong, G S Salvesen, M Pericak-Vance, D Schmechel, A M Saunders, D Goldgaber, A D Rose. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 17. 1993-10-05. PMID:8367470. |
late-onset familial and sporadic alzheimer disease patients have an increased frequency of one of the three common apoe alleles, epsilon 4, suggesting apoe4 is associated with increased susceptibility to disease. |
1993-10-05 |
2023-08-12 |
human |
| W J Strittmatter, K H Weisgraber, D Y Huang, L M Dong, G S Salvesen, M Pericak-Vance, D Schmechel, A M Saunders, D Goldgaber, A D Rose. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 17. 1993-10-05. PMID:8367470. |
binding of beta/a4 peptide by oxidized apoe may determine the sequestration or targeting of either apoe or beta/a4 peptide, and isoform-specific differences in apoe binding or oxidation may be involved in the pathogenesis of the intra- and extracellular lesions of alzheimer disease. |
1993-10-05 |
2023-08-12 |
human |
| A M Saunders, W J Strittmatter, D Schmechel, P H George-Hyslop, M A Pericak-Vance, S H Joo, B L Rosi, J F Gusella, D R Crapper-MacLachlan, M J Albert. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology. vol 43. issue 8. 1993-09-15. PMID:8350998. |
apolipoprotein e, type epsilon 4 allele (apoe epsilon 4), is associated with late-onset familial alzheimer's disease (ad). |
1993-09-15 |
2023-08-12 |
Not clear |
| J Bignal. APOE gene dose in Alzheimer's disease. Lancet (London, England). vol 342. issue 8868. 1993-09-02. PMID:8101911. |
apoe gene dose in alzheimer's disease. |
1993-09-02 |
2023-08-12 |
Not clear |