| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andreas Ihle, David Bunce, Matthias Kliege. APOE ε4 and cognitive function in early life: a meta-analysis. Neuropsychology. vol 26. issue 3. 2012-09-14. PMID:22329498. |
it is well established that the apolipoprotein e (apoe) ε4 allele is associated with cognitive impairment and alzheimer's disease in old age. |
2012-09-14 |
2023-08-12 |
Not clear |
| Cheng-Sheng Chen, Pei Ouyang, Yi-Chun Yeh, Chiou-Lian Lai, Ching-Kuan Liu, Cheng-Fang Yen, Chih-Hung Ko, Ju-Yu Yen, Gin-Chun Liu, Suh-Hang Hank Ju. Apolipoprotein E polymorphism and behavioral and psychological symptoms of dementia in patients with Alzheimer disease. Alzheimer disease and associated disorders. vol 26. issue 2. 2012-09-13. PMID:21617520. |
the aims of this study were to identify subsyndromes of behavioral and psychological symptoms of dementia (bpsd) in alzheimer disease (ad), and to investigate whether the apolipoprotein e (apoe) gene confers a risk of distinct bpsd subsyndromes. |
2012-09-13 |
2023-08-12 |
Not clear |
| Lilian Calderón-Garcidueñas, Michael Kavanaugh, Michelle Block, Amedeo D'Angiulli, Ricardo Delgado-Chávez, Ricardo Torres-Jardón, Angelica González-Maciel, Rafael Reynoso-Robles, Norma Osnaya, Rodolfo Villarreal-Calderon, Ruixin Guo, Zhaowei Hua, Hongtu Zhu, George Perry, Philippe Dia. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. Journal of Alzheimer's disease : JAD. vol 28. issue 1. 2012-09-12. PMID:21955814. |
the effect of apolipoprotein e (apoe) genotype on the presence of protein aggregates associated with alzheimer's disease (ad) pathology was also explored. |
2012-09-12 |
2023-08-12 |
human |
| Matthew J Gallek, Leslie Ritte. Central nervous system genomics. Annual review of nursing research. vol 29. 2012-09-11. PMID:22891506. |
apoe was first tied to the risk of alzheimer's disease and has since then been investigated in traumatic brain injury and hemorrhagic strokes. |
2012-09-11 |
2023-08-12 |
Not clear |
| M Reale, M A Kamal, L Velluto, D Gambi, M Di Nicola, N H Grei. Relationship between inflammatory mediators, Aβ levels and ApoE genotype in Alzheimer disease. Current Alzheimer research. vol 9. issue 4. 2012-09-07. PMID:22272623. |
relationship between inflammatory mediators, aβ levels and apoe genotype in alzheimer disease. |
2012-09-07 |
2023-08-12 |
human |
| John M Ringman, David Elashoff, Daniel H Geschwind, Brian T Welsh, Karen H Gylys, Cathy Lee, Jeffrey L Cummings, Greg M Col. Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype. Archives of neurology. vol 69. issue 6. 2012-08-31. PMID:22689192. |
plasma signaling proteins in persons at genetic risk for alzheimer disease: influence of apoe genotype. |
2012-08-31 |
2023-08-12 |
Not clear |
| John M Ringman, David Elashoff, Daniel H Geschwind, Brian T Welsh, Karen H Gylys, Cathy Lee, Jeffrey L Cummings, Greg M Col. Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype. Archives of neurology. vol 69. issue 6. 2012-08-31. PMID:22689192. |
to study the effect of familial alzheimer disease (fad) mutations and apoe genotype on plasma signaling protein levels. |
2012-08-31 |
2023-08-12 |
Not clear |
| Bhavani Shankara Bagepally, Harsha N Halahalli, John P John, Lakshminarayan Kota, Meera Purushottam, Odity Mukherjee, Palanimuthu Thangaraju Sivakumar, Srikala Bharath, Sanjeev Jain, Mathew Varghes. Apolipoprotein E4 and brain white matter integrity in Alzheimer's disease: tract-based spatial statistics study under 3-Tesla MRI. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22269984. |
apolipoprotein e4 (apoe ε4) polymorphism is a known genetic risk factor for alzheimer's disease (ad). |
2012-08-29 |
2023-08-12 |
Not clear |
| M P Vitek, D J Christensen, D Wilcock, J Davis, W E Van Nostrand, F Q Li, C A Colto. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22326991. |
after age, the second largest risk factor for alzheimer's disease (ad) is apolipoprotein e (apoe) genotype, where apoe4 is associated with lower apoe protein levels, more severer brain pathology, enhanced inflammation and disease. |
2012-08-29 |
2023-08-12 |
Not clear |
| Ina Caesar, Sam Gand. Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease. BMC medicine. vol 10. 2012-08-27. PMID:22502767. |
evidence that an apoe ε4 'double whammy' increases risk for alzheimer's disease. |
2012-08-27 |
2023-08-12 |
Not clear |
| Chris Carte. Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System. International journal of Alzheimer's disease. vol 2011. 2012-08-23. PMID:22254144. |
alzheimer's disease: app, gamma secretase, apoe, clu, cr1, picalm, abca7, bin1, cd2ap, cd33, epha1, and ms4a2, and their relationships with herpes simplex, c. pneumoniae, other suspect pathogens, and the immune system. |
2012-08-23 |
2023-08-12 |
human |
| Satya Vani Guttula, Apparao Allam, R Sridhar Gumpen. Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22482075. |
three genes, sorl1, app, and apoe, are suspected to cause alzheimer's whereas the other 21 genes are related to other diseases but may also be found to be associated with alzheimer's, and these are tmem59, cct4, igf2r, sfpq, prdx3, rnf14, ids, ssbp1, syne2, txnl4a, stxbp3, smarcb1, ulk2, agtpbp1, fabp7, calb1, h2afy, copa, sap18, atic and syncrip. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tariq Ahmad Masoodi, Sulaiman A Al Shammari, May N Al-Muammar, Adel A Alhamda. Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease. Neurology research international. vol 2012. 2012-08-23. PMID:22530123. |
screening and evaluation of deleterious snps in apoe gene of alzheimer's disease. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tariq Ahmad Masoodi, Sulaiman A Al Shammari, May N Al-Muammar, Adel A Alhamda. Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease. Neurology research international. vol 2012. 2012-08-23. PMID:22530123. |
apolipoprotein e (apoe) is an important risk factor for alzheimer's disease (ad) and is present in 30-50% of patients who develop late-onset ad. |
2012-08-23 |
2023-08-12 |
Not clear |
| Beata Ferencz, Sari Karlsson, Grégoria Kalpouzo. Promising Genetic Biomarkers of Preclinical Alzheimer's Disease: The Influence of APOE and TOMM40 on Brain Integrity. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22550605. |
promising genetic biomarkers of preclinical alzheimer's disease: the influence of apoe and tomm40 on brain integrity. |
2012-08-23 |
2023-08-12 |
Not clear |
| H R Khorram Khorshid, E Gozalpour, K Kamali, M Ohadi, M Karimloo, M H Shahhossein. The Association between Sporadic Alzheimer's Disease and the Human ABCA1 and APOE Gene Polymorphisms in Iranian Population. Iranian Red Crescent medical journal. vol 13. issue 4. 2012-08-23. PMID:22737475. |
the association between sporadic alzheimer's disease and the human abca1 and apoe gene polymorphisms in iranian population. |
2012-08-23 |
2023-08-12 |
human |
| H R Khorram Khorshid, E Gozalpour, K Kamali, M Ohadi, M Karimloo, M H Shahhossein. The Association between Sporadic Alzheimer's Disease and the Human ABCA1 and APOE Gene Polymorphisms in Iranian Population. Iranian Red Crescent medical journal. vol 13. issue 4. 2012-08-23. PMID:22737475. |
apolipoprotein e (apoe), which its ε4 allele has been reported as a risk factor in late onset alzheimer's disease (ad), is the main cholesterol carrier in the brain. |
2012-08-23 |
2023-08-12 |
human |
| Hui-Fu Wang, Jin-Tai Yu, Wei Zhang, Wei Wang, Qiu-Yan Liu, Xiao-Ying Ma, Hua-Min Ding, Lan Ta. SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population. Brain research. vol 1448. 2012-08-20. PMID:22353753. |
sorcs1 and apoe polymorphisms interact to confer risk for late-onset alzheimer's disease in a northern han chinese population. |
2012-08-20 |
2023-08-12 |
human |
| Taher Darreh-Shori, Anton Forsberg, Negar Modiri, Niels Andreasen, Kaj Blennow, Chelenk Kamil, Hiba Ahmed, Ove Almkvist, Bengt Långström, Agneta Nordber. Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20538374. |
recently, we reported that 3 of the known risk factors of alzheimer's disease (ad), i.e., advanced age, apolipoprotein e (apoe) ε4, and female gender, are associated with differential levels of apoe proteins and butyrylcholinesterase (buche) in the cerebrospinal fluid (csf) of ad patients. |
2012-08-08 |
2023-08-12 |
Not clear |
| Cécilia Samieri, Catherine Féart, Cécile Proust-Lima, Evelyne Peuchant, Jean-François Dartigues, Hélène Amieva, Pascale Barberger-Gatea. ω-3 fatty acids and cognitive decline: modulation by ApoEε4 allele and depression. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20570406. |
the ε4 allele of the apolipoproteine (apoe), the main genetic risk factor for alzheimer's disease, and depressive symptoms, which are frequently associated with cognitive impairment in older persons, may modify this relationship. |
2012-08-08 |
2023-08-12 |
human |