| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew J Gallek, Leslie Ritte. Central nervous system genomics. Annual review of nursing research. vol 29. 2012-09-11. PMID:22891506. |
apoe was first tied to the risk of alzheimer's disease and has since then been investigated in traumatic brain injury and hemorrhagic strokes. |
2012-09-11 |
2023-08-12 |
Not clear |
| M Reale, M A Kamal, L Velluto, D Gambi, M Di Nicola, N H Grei. Relationship between inflammatory mediators, Aβ levels and ApoE genotype in Alzheimer disease. Current Alzheimer research. vol 9. issue 4. 2012-09-07. PMID:22272623. |
relationship between inflammatory mediators, aβ levels and apoe genotype in alzheimer disease. |
2012-09-07 |
2023-08-12 |
human |
| John M Ringman, David Elashoff, Daniel H Geschwind, Brian T Welsh, Karen H Gylys, Cathy Lee, Jeffrey L Cummings, Greg M Col. Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype. Archives of neurology. vol 69. issue 6. 2012-08-31. PMID:22689192. |
plasma signaling proteins in persons at genetic risk for alzheimer disease: influence of apoe genotype. |
2012-08-31 |
2023-08-12 |
Not clear |
| John M Ringman, David Elashoff, Daniel H Geschwind, Brian T Welsh, Karen H Gylys, Cathy Lee, Jeffrey L Cummings, Greg M Col. Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype. Archives of neurology. vol 69. issue 6. 2012-08-31. PMID:22689192. |
to study the effect of familial alzheimer disease (fad) mutations and apoe genotype on plasma signaling protein levels. |
2012-08-31 |
2023-08-12 |
Not clear |
| Bhavani Shankara Bagepally, Harsha N Halahalli, John P John, Lakshminarayan Kota, Meera Purushottam, Odity Mukherjee, Palanimuthu Thangaraju Sivakumar, Srikala Bharath, Sanjeev Jain, Mathew Varghes. Apolipoprotein E4 and brain white matter integrity in Alzheimer's disease: tract-based spatial statistics study under 3-Tesla MRI. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22269984. |
apolipoprotein e4 (apoe ε4) polymorphism is a known genetic risk factor for alzheimer's disease (ad). |
2012-08-29 |
2023-08-12 |
Not clear |
| M P Vitek, D J Christensen, D Wilcock, J Davis, W E Van Nostrand, F Q Li, C A Colto. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-degenerative diseases. vol 10. issue 1-4. 2012-08-29. PMID:22326991. |
after age, the second largest risk factor for alzheimer's disease (ad) is apolipoprotein e (apoe) genotype, where apoe4 is associated with lower apoe protein levels, more severer brain pathology, enhanced inflammation and disease. |
2012-08-29 |
2023-08-12 |
Not clear |
| Ina Caesar, Sam Gand. Evidence that an APOE ε4 'double whammy' increases risk for Alzheimer's disease. BMC medicine. vol 10. 2012-08-27. PMID:22502767. |
evidence that an apoe ε4 'double whammy' increases risk for alzheimer's disease. |
2012-08-27 |
2023-08-12 |
Not clear |
| Chris Carte. Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System. International journal of Alzheimer's disease. vol 2011. 2012-08-23. PMID:22254144. |
alzheimer's disease: app, gamma secretase, apoe, clu, cr1, picalm, abca7, bin1, cd2ap, cd33, epha1, and ms4a2, and their relationships with herpes simplex, c. pneumoniae, other suspect pathogens, and the immune system. |
2012-08-23 |
2023-08-12 |
human |
| Satya Vani Guttula, Apparao Allam, R Sridhar Gumpen. Analyzing microarray data of Alzheimer's using cluster analysis to identify the biomarker genes. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22482075. |
three genes, sorl1, app, and apoe, are suspected to cause alzheimer's whereas the other 21 genes are related to other diseases but may also be found to be associated with alzheimer's, and these are tmem59, cct4, igf2r, sfpq, prdx3, rnf14, ids, ssbp1, syne2, txnl4a, stxbp3, smarcb1, ulk2, agtpbp1, fabp7, calb1, h2afy, copa, sap18, atic and syncrip. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tariq Ahmad Masoodi, Sulaiman A Al Shammari, May N Al-Muammar, Adel A Alhamda. Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease. Neurology research international. vol 2012. 2012-08-23. PMID:22530123. |
screening and evaluation of deleterious snps in apoe gene of alzheimer's disease. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tariq Ahmad Masoodi, Sulaiman A Al Shammari, May N Al-Muammar, Adel A Alhamda. Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease. Neurology research international. vol 2012. 2012-08-23. PMID:22530123. |
apolipoprotein e (apoe) is an important risk factor for alzheimer's disease (ad) and is present in 30-50% of patients who develop late-onset ad. |
2012-08-23 |
2023-08-12 |
Not clear |
| Beata Ferencz, Sari Karlsson, Grégoria Kalpouzo. Promising Genetic Biomarkers of Preclinical Alzheimer's Disease: The Influence of APOE and TOMM40 on Brain Integrity. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22550605. |
promising genetic biomarkers of preclinical alzheimer's disease: the influence of apoe and tomm40 on brain integrity. |
2012-08-23 |
2023-08-12 |
Not clear |
| H R Khorram Khorshid, E Gozalpour, K Kamali, M Ohadi, M Karimloo, M H Shahhossein. The Association between Sporadic Alzheimer's Disease and the Human ABCA1 and APOE Gene Polymorphisms in Iranian Population. Iranian Red Crescent medical journal. vol 13. issue 4. 2012-08-23. PMID:22737475. |
the association between sporadic alzheimer's disease and the human abca1 and apoe gene polymorphisms in iranian population. |
2012-08-23 |
2023-08-12 |
human |
| H R Khorram Khorshid, E Gozalpour, K Kamali, M Ohadi, M Karimloo, M H Shahhossein. The Association between Sporadic Alzheimer's Disease and the Human ABCA1 and APOE Gene Polymorphisms in Iranian Population. Iranian Red Crescent medical journal. vol 13. issue 4. 2012-08-23. PMID:22737475. |
apolipoprotein e (apoe), which its ε4 allele has been reported as a risk factor in late onset alzheimer's disease (ad), is the main cholesterol carrier in the brain. |
2012-08-23 |
2023-08-12 |
human |
| Hui-Fu Wang, Jin-Tai Yu, Wei Zhang, Wei Wang, Qiu-Yan Liu, Xiao-Ying Ma, Hua-Min Ding, Lan Ta. SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population. Brain research. vol 1448. 2012-08-20. PMID:22353753. |
sorcs1 and apoe polymorphisms interact to confer risk for late-onset alzheimer's disease in a northern han chinese population. |
2012-08-20 |
2023-08-12 |
human |
| Taher Darreh-Shori, Anton Forsberg, Negar Modiri, Niels Andreasen, Kaj Blennow, Chelenk Kamil, Hiba Ahmed, Ove Almkvist, Bengt Långström, Agneta Nordber. Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20538374. |
recently, we reported that 3 of the known risk factors of alzheimer's disease (ad), i.e., advanced age, apolipoprotein e (apoe) ε4, and female gender, are associated with differential levels of apoe proteins and butyrylcholinesterase (buche) in the cerebrospinal fluid (csf) of ad patients. |
2012-08-08 |
2023-08-12 |
Not clear |
| Cécilia Samieri, Catherine Féart, Cécile Proust-Lima, Evelyne Peuchant, Jean-François Dartigues, Hélène Amieva, Pascale Barberger-Gatea. ω-3 fatty acids and cognitive decline: modulation by ApoEε4 allele and depression. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:20570406. |
the ε4 allele of the apolipoproteine (apoe), the main genetic risk factor for alzheimer's disease, and depressive symptoms, which are frequently associated with cognitive impairment in older persons, may modify this relationship. |
2012-08-08 |
2023-08-12 |
human |
| Su Hee Chu, Kathryn Roeder, Robert E Ferrell, Bernie Devlin, Mary Ann A DeMichele-Sweet, M Ilyas Kamboh, Oscar L Lopez, Robert A Swee. TOMM40 poly-T repeat lengths, age of onset and psychosis risk in Alzheimer disease. Neurobiology of aging. vol 32. issue 12. 2012-08-08. PMID:21820212. |
apolipoprotein e (apoe) ε4 alleles increase the risk for late-onset alzheimer disease (load) and decrease the age of onset. |
2012-08-08 |
2023-08-12 |
human |
| James F Morley, Sharon X Xie, Howard I Hurtig, Matthew B Stern, Amy Colcher, Stacy Horn, Nabila Dahodwala, John E Duda, Daniel Weintraub, Alice S Chen-Plotkin, Vivianna Van Deerlin, Dana Falcone, Andrew Siderow. Genetic influences on cognitive decline in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 4. 2012-08-08. PMID:22344634. |
carrying at least one apoe ε4 allele is associated with more rapid cognitive decline in pd, supporting the idea of a component of shared etiology between pd dementia and alzheimer's disease. |
2012-08-08 |
2023-08-12 |
Not clear |
| Kewei Chen, Napatkamon Ayutyanont, Jessica B S Langbaum, Adam S Fleisher, Cole Reschke, Wendy Lee, Xiaofen Liu, Gene E Alexander, Dan Bandy, Richard J Caselli, Eric M Reima. Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E ε4 gene dose in cognitively normal adults: a cross-validation study using voxel-based multi-modal partial least squares. NeuroImage. vol 60. issue 4. 2012-08-03. PMID:22348880. |
here we used it to demonstrate a strong correlation between mmpls scores to characterize the linkage between the covarying patterns of fluorodeoxyglucose positron emission tomography (fdg pet) measurements of regional glucose metabolism and magnetic resonance imaging (mri) measurements of regional gray matter associated with apolipoprotein e (apoe) ε4 gene dose (i.e., three levels of genetic risk for late-onset alzheimer's disease (ad)) in cognitively normal, late-middle-aged persons. |
2012-08-03 |
2023-08-12 |
human |