| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Zhong, Xueli Zheng, Ya Miao, Lili Wan, Hong Yan, Beiyun Wan. Effect of CYP2D6*10 and APOE polymorphisms on the efficacy of donepezil in patients with Alzheimer's disease. The American journal of the medical sciences. vol 345. issue 3. 2013-04-19. PMID:22986607. |
the aim of this study was to evaluate the effect of cyp2d6*10 and apoe polymorphisms on both steady-state plasma concentrations (cp) and clinical response of donepezil in patients with mild-to-moderate alzheimer's disease (ad). |
2013-04-19 |
2023-08-12 |
Not clear |
| V Garibotto, B Borroni, S Sorbi, S F Cappa, A Padovani, D Peran. Education and occupation provide reserve in both ApoE ε4 carrier and noncarrier patients with probable Alzheimer's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 33. issue 5. 2013-04-18. PMID:22173784. |
education and occupation provide reserve in both apoe ε4 carrier and noncarrier patients with probable alzheimer's disease. |
2013-04-18 |
2023-08-12 |
human |
| Leonides Canuet, Ivan Tellado, Veronica Couceiro, Carmen Fraile, Lucia Fernandez-Novoa, Ryouhei Ishii, Masatoshi Takeda, Ramon Cacabelo. Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. PloS one. vol 7. issue 9. 2013-04-10. PMID:23050006. |
resting-state network disruption and apoe genotype in alzheimer's disease: a lagged functional connectivity study. |
2013-04-10 |
2023-08-12 |
Not clear |
| Tomoyuki Nagata, Shunichiro Shinagawa, Bolati Kuerban, Nobuto Shibata, Tohru Ohnuma, Heii Arai, Kazuhiko Nakayama, Hisashi Yamad. Age-Related Association between Apolipoprotein E ε4 and Cognitive Function in Japanese Patients with Alzheimer's Disease. Dementia and geriatric cognitive disorders extra. vol 3. issue 1. 2013-04-10. PMID:23569459. |
in the present study, we investigated whether apolipoprotein e (apoe) polymorphisms influenced the cognitive function of japanese patients with alzheimer's disease (ad) at certain ages. |
2013-04-10 |
2023-08-12 |
Not clear |
| Tomoyuki Ohara, Toshiharu Ninomiya, Yoichiro Hirakawa, Kyota Ashikawa, Akira Monji, Yutaka Kiyohara, Shigenobu Kanba, Michiaki Kub. Association study of susceptibility genes for late-onset Alzheimer's disease in the Japanese population. Psychiatric genetics. vol 22. issue 6. 2013-04-02. PMID:22935915. |
apoe is an established susceptibility gene for late-onset alzheimer's disease (load). |
2013-04-02 |
2023-08-12 |
Not clear |
| Rik Ossenkoppele, Wiesje M van der Flier, Marissa D Zwan, Sofie F Adriaanse, Ronald Boellaard, Albert D Windhorst, Frederik Barkhof, Adriaan A Lammertsma, Philip Scheltens, Bart N M van Bercke. Differential effect of APOE genotype on amyloid load and glucose metabolism in AD dementia. Neurology. vol 80. issue 4. 2013-03-19. PMID:23255822. |
to examine the relationships between apolipoprotein e (apoe) ε4 dose and in vivo distributions of both fibrillary amyloid burden and glucose metabolism in the same alzheimer disease dementia patients, selected for abnormal amyloid imaging. |
2013-03-19 |
2023-08-12 |
Not clear |
| Gene E Alexander, Kaitlin L Bergfield, Kewei Chen, Eric M Reiman, Krista D Hanson, Lan Lin, Daniel Bandy, Richard J Caselli, James R Moelle. Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults. Neurobiology of aging. vol 33. issue 12. 2013-03-12. PMID:22405043. |
the apolipoprotein e (apoe) ε4 allele increases the risk for late-onset alzheimer's disease (ad) and age-related cognitive decline. |
2013-03-12 |
2023-08-12 |
Not clear |
| Anne-Sophie Carlo, Camilla Gustafsen, Guido Mastrobuoni, Morten S Nielsen, Tilman Burgert, Daniela Hartl, Michael Rohe, Anders Nykjaer, Joachim Herz, Joerg Heeren, Stefan Kempa, Claus Munck Petersen, Thomas E Willno. The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 1. 2013-03-12. PMID:23283348. |
apolipoprotein e (apoe) is the major risk factor for sporadic alzheimer's disease. |
2013-03-12 |
2023-08-12 |
mouse |
| Rita J Guerreiro, John Hard. TOMM40 association with Alzheimer disease: tales of APOE and linkage disequilibrium. Archives of neurology. vol 69. issue 10. 2013-03-11. PMID:22869030. |
tomm40 association with alzheimer disease: tales of apoe and linkage disequilibrium. |
2013-03-11 |
2023-08-12 |
Not clear |
| Gyungah Jun, Badri N Vardarajan, Jacqueline Buros, Chang-En Yu, Michele V Hawk, Beth A Dombroski, Paul K Crane, Eric B Larson, Richard Mayeux, Jonathan L Haines, Kathryn L Lunetta, Margaret A Pericak-Vance, Gerard D Schellenberg, Lindsay A Farre. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Archives of neurology. vol 69. issue 10. 2013-03-11. PMID:22869155. |
comprehensive search for alzheimer disease susceptibility loci in the apoe region. |
2013-03-11 |
2023-08-12 |
Not clear |
| Gyungah Jun, Badri N Vardarajan, Jacqueline Buros, Chang-En Yu, Michele V Hawk, Beth A Dombroski, Paul K Crane, Eric B Larson, Richard Mayeux, Jonathan L Haines, Kathryn L Lunetta, Margaret A Pericak-Vance, Gerard D Schellenberg, Lindsay A Farre. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Archives of neurology. vol 69. issue 10. 2013-03-11. PMID:22869155. |
to evaluate the association of risk and age at onset (aao) of alzheimer disease (ad) with single-nucleotide polymorphisms (snps) in the chromosome 19 region including apolipoprotein e (apoe) and a repeat-length polymorphism in tomm40 (poly-t, rs10524523). |
2013-03-11 |
2023-08-12 |
Not clear |
| M I Kamboh, F Y Demirci, X Wang, R L Minster, M M Carrasquillo, V S Pankratz, S G Younkin, A J Saykin, G Jun, C Baldwin, M W Logue, J Buros, L Farrer, M A Pericak-Vance, J L Haines, R A Sweet, M Ganguli, E Feingold, S T Dekosky, O L Lopez, M M Barmad. Genome-wide association study of Alzheimer's disease. Translational psychiatry. vol 2. 2013-03-04. PMID:22832961. |
in addition to apolipoprotein e (apoe), recent large genome-wide association studies (gwass) have identified nine other genes/loci (cr1, bin1, clu, picalm, ms4a4/ms4a6e, cd2ap, cd33, epha1 and abca7) for late-onset alzheimer's disease (load). |
2013-03-04 |
2023-08-12 |
Not clear |
| Katherine J Bangen, Khaled Restom, Thomas T Liu, Christina E Wierenga, Amy J Jak, David P Salmon, Mark W Bond. Assessment of Alzheimer's disease risk with functional magnetic resonance imaging: an arterial spin labeling study. Journal of Alzheimer's disease : JAD. vol 31 Suppl 3. 2013-02-22. PMID:22531427. |
functional magnetic resonance imaging (fmri) of older adults at risk for alzheimer's disease (ad) by virtue of their cognitive (i.e., mild cognitive impairment [mci]) and/or genetic (i.e., apolipoprotein e [apoe] ε4 allele) status demonstrate divergent brain response patterns during memory encoding across studies. |
2013-02-22 |
2023-08-12 |
Not clear |
| Lei Yu, Patricia Boyle, Robert S Wilson, Eisuke Segawa, Sue Leurgans, Philip L De Jager, David A Bennet. A random change point model for cognitive decline in Alzheimer's disease and mild cognitive impairment. Neuroepidemiology. vol 39. issue 2. 2013-02-22. PMID:22814083. |
we present a random change point model to characterize decline in cognition among community-based elderly who developed alzheimer's disease (ad) or amnestic mild cognitive impairment (mci), and to examine how decline varies with age, sex, education, and apoe status. |
2013-02-22 |
2023-08-12 |
Not clear |
| Katherine L Youmans, Leon M Tai, Evelyn Nwabuisi-Heath, Lisa Jungbauer, Takahisa Kanekiyo, Ming Gan, Jungsu Kim, William A Eimer, Steve Estus, G William Rebeck, Edwin J Weeber, Guojun Bu, Chunjiang Yu, Mary Jo Lad. APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease. The Journal of biological chemistry. vol 287. issue 50. 2013-02-12. PMID:23060451. |
apoe4 is the greatest risk factor for alzheimer disease (ad) and synergistic effects with amyloid-β peptide (aβ) suggest interactions among apoe isoforms and different forms of aβ accumulation. |
2013-02-12 |
2023-08-12 |
mouse |
| Sonya B Dumanis, Amanda M DiBattista, Matthew Miessau, Charbel E H Moussa, G William Rebec. APOE genotype affects the pre-synaptic compartment of glutamatergic nerve terminals. Journal of neurochemistry. vol 124. issue 1. 2013-02-07. PMID:22862561. |
apolipoprotein e (apoe) genotype affects outcomes of alzheimer's disease and other conditions of brain damage. |
2013-02-07 |
2023-08-12 |
mouse |
| Mandeep Singh, Jason T Schott, Martin A Leon, Robert T Granata, Harkiran K Dhah, Jason A Welles, Michelle A Boyce, Hafeez S Oseni-Olalemi, Charles E Mordaunt, Anthony J Vargas, Nilay V Patel, Santanu Maitr. Design, synthesis and identification of a new class of triarylmethyl amine compounds as inhibitors of apolipoprotein E production. Bioorganic & medicinal chemistry letters. vol 22. issue 19. 2013-02-04. PMID:22959206. |
apoe is a cholesterol- and lipid-carrier protein implicated in aging, atherosclerosis, alzheimer's disease (ad), and other neurological and lipid-related disorders. |
2013-02-04 |
2023-08-12 |
Not clear |
| Krikor Dikranian, Jungsu Kim, Floy R Stewart, Marilyn A Levy, David M Holtzma. Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer's disease. International journal of clinical and experimental pathology. vol 5. issue 6. 2013-01-31. PMID:22949930. |
ultrastructural studies in app/ps1 mice expressing human apoe isoforms: implications for alzheimer's disease. |
2013-01-31 |
2023-08-12 |
mouse |
| Saeed Sadigh-Eteghad, Mahnaz Talebi, Mehdi Farhoud. Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer`s disease. A meta-analysis. Neurosciences (Riyadh, Saudi Arabia). vol 17. issue 4. 2013-01-30. PMID:23022896. |
to obtain a better insight into the effect of the epsilon (e) 4 allele of the apolipoprotein e gene (apoe) on the risk of late onset alzheimer`s disease (load), and assess its heterogeneity in geographic regions. |
2013-01-30 |
2023-08-12 |
Not clear |
| Erling Tjelta Westlye, Erlend Hodneland, Judit Haász, Thomas Espeseth, Arvid Lundervold, Astri J Lundervol. Episodic memory of APOE ε4 carriers is correlated with fractional anisotropy, but not cortical thickness, in the medial temporal lobe. NeuroImage. vol 63. issue 1. 2013-01-29. PMID:22796460. |
the ε4 allele of apolipoprotein e (apoe, protein; apoe, gene) is the most important genetic risk factor for the development of alzheimer's disease (ad). |
2013-01-29 |
2023-08-12 |
human |