| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Xing, Yi Tang, Jianping Ji. Sex Differences in Neuropsychiatric Symptoms of Alzheimer's Disease: The Modifying Effect of Apolipoprotein E ε4 Status. Behavioural neurology. vol 2015. 2016-07-26. PMID:26538817. |
sex differences in neuropsychiatric symptoms of alzheimer's disease (ad) have been demonstrated in previous studies, and apolipoprotein e (apoe) ε4 status influences psychiatric manifestations of ad. |
2016-07-26 |
2023-08-13 |
Not clear |
| Jessica Foraker, Steven P Millard, Lesley Leong, Zachary Thomson, Sunny Chen, C Dirk Keene, Lynn M Bekris, Chang-En Y. The APOE Gene is Differentially Methylated in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 48. issue 3. 2016-07-14. PMID:26402071. |
the apoe gene is differentially methylated in alzheimer's disease. |
2016-07-14 |
2023-08-13 |
human |
| Jessica Foraker, Steven P Millard, Lesley Leong, Zachary Thomson, Sunny Chen, C Dirk Keene, Lynn M Bekris, Chang-En Y. The APOE Gene is Differentially Methylated in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 48. issue 3. 2016-07-14. PMID:26402071. |
the ɛ4 allele of the human apolipoprotein e gene (apoe) is a well-proven genetic risk factor for the late onset form of alzheimer's disease (ad). |
2016-07-14 |
2023-08-13 |
human |
| Sisi Zhang, Yaojing Chen, Zhen Liu, Junying Zhang, Xin Li, Ruixue Cui, Zhanjun Zhan. Association of White Matter Integrity and Cognitive Functions in Chinese Non-Demented Elderly with the APOE ɛ4 Allele. Journal of Alzheimer's disease : JAD. vol 48. issue 3. 2016-07-14. PMID:26402101. |
the apolipoprotein e (apoe) ɛ4 allele is the strongest genetic risk factor for alzheimer's disease (ad). |
2016-07-14 |
2023-08-13 |
Not clear |
| Fan-Tao Meng, Jun Zhao, Hui Fang, Ya-Jing Li. The influence of chronic stress on anxiety-like behavior and cognitive function in different human GFAP-ApoE transgenic adult male mice. Stress (Amsterdam, Netherlands). vol 18. issue 4. 2016-07-13. PMID:25938810. |
the apolipoprotein e (apoe) ɛ4 allele (apoe4) is an important genetic risk factor for the pathogenesis of alzheimer's disease (ad). |
2016-07-13 |
2023-08-13 |
mouse |
| Ye Zhou, Wenjuan Zhao, Nour Al-Muhtasib, G William Rebec. APOE Genotype Alters Immunoglobulin Subtypes in Knock-In Mice. Journal of Alzheimer's disease : JAD. vol 46. issue 2. 2016-07-11. PMID:25737044. |
apolipoprotein e (apoe) alleles are strongly related to the risk of alzheimer's disease (ad). |
2016-07-11 |
2023-08-13 |
mouse |
| Young-Min Lee, Ji-Kyung Ha, Je-Min Park, Byung-Dae Lee, EunSoo Moon, Young-In Chung, Ji-Hoon Kim, Hak-Jin Kim, Chi-Woong Mun, Tae-Hyung Kim, Young-Hoon Ki. Apolipoprotein E genotype modulates effects of vitamin B12 and homocysteine on grey matter volume in Alzheimer's disease. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. vol 16. issue 1. 2016-07-06. PMID:25919635. |
we examined the effects in each subgroup (apoe ε4 carriers and non-carriers) of alzheimer's disease (ad) patients and healthy normal controls. |
2016-07-06 |
2023-08-13 |
Not clear |
| Xiaoying Tang, Dominic Holland, Anders M Dale, Michael I Mille. APOE Affects the Volume and Shape of the Amygdala and the Hippocampus in Mild Cognitive Impairment and Alzheimer's Disease: Age Matters. Journal of Alzheimer's disease : JAD. vol 47. issue 3. 2016-07-06. PMID:26401700. |
apoe affects the volume and shape of the amygdala and the hippocampus in mild cognitive impairment and alzheimer's disease: age matters. |
2016-07-06 |
2023-08-13 |
Not clear |
| Xiaoying Tang, Dominic Holland, Anders M Dale, Michael I Mille. APOE Affects the Volume and Shape of the Amygdala and the Hippocampus in Mild Cognitive Impairment and Alzheimer's Disease: Age Matters. Journal of Alzheimer's disease : JAD. vol 47. issue 3. 2016-07-06. PMID:26401700. |
this paper examines how age intervenes in the effects of apoe ɛ4 allele on the volume and shape morphometrics of the hippocampus and the amygdala in mild cognitive impairment (mci) and alzheimer's disease. |
2016-07-06 |
2023-08-13 |
Not clear |
| Flavio Dell'Acqua, Wasim Khan, Natalie Gottlieb, Vincent Giampietro, Cedric Ginestet, David Bouls, Steven Newhouse, Richard Dobson, Tobias Banaschewski, Gareth J Barker, Arun L W Bokde, Christian Büchel, Patricia Conrod, Herta Flor, Vincent Frouin, Hugh Garavan, Penny Gowland, Anreas Heinz, Hervé Lemaítre, Frauke Nees, Tomas Paus, Zdenka Pausova, Marcella Rietschel, Michael N Smolka, Andreas Ströhle, Jean Gallinat, Eric Westman, Gunther Schumann, Simon Lovestone, Andrew Simmon. Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE ɛ4 and ɛ2 Alleles in Young Healthy Adolescents. Journal of Alzheimer's disease : JAD. vol 47. issue 4. 2016-07-06. PMID:26401776. |
the apolipoprotein e (apoe) ɛ4 allele is the best established genetic risk factor for alzheimer's disease (ad) and has been previously associated with alterations in structural gray matter and changes in functional brain activity in healthy middle-aged individuals and older non-demented subjects. |
2016-07-06 |
2023-08-13 |
human |
| Christian Schmidt, Nicole Gerlach, Matthias Schmitz, Tobias Thom, Katharina Kramer, Tim Friede, Inga Zer. Baseline CSF/Serum-Ratio of Apolipoprotein E and Rate of Differential Decline in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 48. issue 1. 2016-07-06. PMID:26401939. |
apolipoprotein e (apoe) has an active part in the pathogenesis of alzheimer's disease (ad). |
2016-07-06 |
2023-08-13 |
Not clear |
| Raffaele Ferrari, Michela Ferrara, Anwar Alinani, Roger Brian Sutton, Francesco Famà, Agnese Picco, Guido Rodriguez, Flavio Nobili, Parastoo Momen. Screening of Early and Late Onset Alzheimer's Disease Genetic Risk Factors in a Cohort of Dementia Patients from Liguria, Italy. Current Alzheimer research. vol 12. issue 8. 2016-07-01. PMID:26159191. |
we screened 37 ad, 8 mild cognitive impairment (mci), 3 ad and cvd (cerebrovascular disease), 3 mci and cvd, 8 frontotemporal dementia (ftd) and 2 progressive supranuclear palsy (psp) patients, and 28 normal controls (ncs).we sequenced psen1, psen2 and app (eoad risk factors), as well as mapt, grn and tardbp for all cases and ncs, and analysed the apoe, clu, cr1 and picalm genotypes as well as the mapt and ace haplotypes (load risk factors) for the ad (n = 37) and ad + mci (n = 45) cases and ncs (n = 28).we identified variants in psen1, psen2 and tardbp across a range of phenotypes (ad, ad and cvd, ftd and psp), suggesting that screening of all known candidate genes of alzheimer's and non-alzheimer's forms of dementias in all dementia cases might be warranted. |
2016-07-01 |
2023-08-13 |
Not clear |
| J. Wesson Ashfor. Treatment of Alzheimer's Disease: The Legacy of the Cholinergic Hypothesis, Neuroplasticity, and Future Directions. Journal of Alzheimer's disease : JAD. vol 47. issue 1. 2016-06-29. PMID:26402763. |
provides a meta-analysis of the effects of apo-lipo-protein e (apoe) genotype on the beneficial effect of acetyl-cholinesterase inhibitors (acheis) in patients with alzheimer's disease (ad). |
2016-06-29 |
2023-08-13 |
Not clear |
| Jeriel Thomas-Richard Keeney, Shaher Ibrahimi, Liqin Zha. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention. Journal of Alzheimer's disease : JAD. vol 48. issue 2. 2016-06-28. PMID:26402005. |
human apoe isoforms differentially modulate glucose and amyloid metabolic pathways in female brain: evidence of the mechanism of neuroprotection by apoe2 and implications for alzheimer's disease prevention and early intervention. |
2016-06-28 |
2023-08-13 |
mouse |
| Jeriel Thomas-Richard Keeney, Shaher Ibrahimi, Liqin Zha. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention. Journal of Alzheimer's disease : JAD. vol 48. issue 2. 2016-06-28. PMID:26402005. |
three major genetic isoforms of apolipoprotein e (apoe), apoe2, apoe3, and apoe4, exist in humans and lead to differences in susceptibility to alzheimer's disease (ad). |
2016-06-28 |
2023-08-13 |
mouse |
| Jeffrey F Waring, Qi Tang, Weining Z Robieson, David P King, Ujjwal Das, Jordan Dubow, Sandeep Dutta, Gerard J Marek, Laura M Gaul. APOE-ɛ4 Carrier Status and Donepezil Response in Patients with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 47. issue 1. 2016-06-28. PMID:26402762. |
previous studies have investigated associations between apolipoprotein e (apoe)-ɛ4 allele status and acetylcholinesterase inhibitor treatment response in patients with alzheimer's disease. |
2016-06-28 |
2023-08-13 |
Not clear |
| Linhong Yuan, Jinmeng Liu, Li Dong, Can Cai, Sisi Wang, Bo Wang, Rong Xia. Effects of APOE rs429358, rs7412 and GSTM1/GSTT1 Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults. Nutrients. vol 7. issue 10. 2016-06-28. PMID:26404360. |
apolipoprotein e (apoe) and oxidative damage were correlated with the risk of alzheimer's disease (ad). |
2016-06-28 |
2023-08-13 |
human |
| Stephanie Oleson, Claire Murph. Olfactory Dysfunction in ApoE ɛ4/4 Homozygotes with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 46. issue 3. 2016-06-27. PMID:25869786. |
olfactory dysfunction in apoe ɛ4/4 homozygotes with alzheimer's disease. |
2016-06-27 |
2023-08-13 |
Not clear |
| Christine Thai, Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Kathryn A Ellis, Stephanie R Rainey-Smith, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruf. Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months. PloS one. vol 10. issue 10. 2016-06-10. PMID:26430784. |
amyloid-related memory decline in preclinical alzheimer's disease is dependent on apoe ε4 and is detectable over 18-months. |
2016-06-10 |
2023-08-13 |
Not clear |
| Christine Thai, Yen Ying Lim, Victor L Villemagne, Simon M Laws, David Ames, Kathryn A Ellis, Stephanie R Rainey-Smith, Ralph N Martins, Colin L Masters, Christopher C Rowe, Paul Maruf. Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months. PloS one. vol 10. issue 10. 2016-06-10. PMID:26430784. |
these results suggest that aβ and apoe ε4 interact to increase the rate of cognitive decline in cn older adults and provide further support for the use of aβ and apoe ε4 as biomarkers of early alzheimer's disease. |
2016-06-10 |
2023-08-13 |
Not clear |