| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J P Shine, C J Hodgetts, M Postans, A D Lawrence, K S Graha. APOE-ε4 selectively modulates posteromedial cortex activity during scene perception and short-term memory in young healthy adults. Scientific reports. vol 5. 2016-09-07. PMID:26552581. |
apolipoprotein e (apoe) ε4 is a major genetic risk factor for alzheimer's disease (ad), yet the mechanisms by which apoe-ε4 influences early-life brain function, and hence, in turn, risk for later-life ad, are poorly understood. |
2016-09-07 |
2023-08-13 |
human |
| Amanda V Tyndall, Laurie Argourd, Tolulope T Sajobi, Margie H Davenport, Scott C Forbes, Stephanie J Gill, Jillian S Parboosingh, Todd J Anderson, Ben J Wilson, Eric E Smith, David B Hogan, Michael D Hill, Marc J Pouli. Cardiometabolic risk factors predict cerebrovascular health in older adults: results from the Brain in Motion study. Physiological reports. vol 4. issue 8. 2016-09-07. PMID:27117804. |
higher v¯p-reactivity in apoe ε4 carriers suggests vascular compensation for deleterious effects of this known risk allele for alzheimer's disease and stroke. |
2016-09-07 |
2023-08-13 |
human |
| Saliha Handan Yildiz, Mujgan Ozdemir Erdogan, Sevilhan Artan, Mustafa Solak, Mehmet Yaman, Belgin Demet Ozbabalik, Evrim Suna Arikan Terz. Association of Alzheimer's Disease With APOE and IL-1α Gene Polymorphisms. American journal of Alzheimer's disease and other dementias. vol 30. issue 8. 2016-09-06. PMID:23038715. |
association of alzheimer's disease with apoe and il-1α gene polymorphisms. |
2016-09-06 |
2023-08-12 |
Not clear |
| Saliha Handan Yildiz, Mujgan Ozdemir Erdogan, Sevilhan Artan, Mustafa Solak, Mehmet Yaman, Belgin Demet Ozbabalik, Evrim Suna Arikan Terz. Association of Alzheimer's Disease With APOE and IL-1α Gene Polymorphisms. American journal of Alzheimer's disease and other dementias. vol 30. issue 8. 2016-09-06. PMID:23038715. |
apolipoprotein e (apoe) gene polymorphisms are thought to be the most important genetic risk factor in the pathogenesis of late onset and sporadic alzheimer's disease (ad). |
2016-09-06 |
2023-08-12 |
Not clear |
| Gerardo Salvat. Does apolipoprotein E genotype influence cognition in middle-aged individuals? Current opinion in neurology. vol 28. issue 6. 2016-09-06. PMID:26402402. |
the apolipoprotein ε4 (apoe ε4) allele has been recognized as a risk factor for the late-onset alzheimer's disease. |
2016-09-06 |
2023-08-13 |
Not clear |
| Chia-Hsiang Che. Development of a Melting Curve-Based Allele-Specific PCR of Apolipoprotein E (APOE) Genotyping Method for Genomic DNA, Guthrie Blood Spot, and Whole Blood. PloS one. vol 11. issue 4. 2016-09-01. PMID:27078154. |
genetic polymorphisms of apolipoprotein e (apoe) are associated with various health conditions and diseases, such as alzheimer's disease, cardiovascular diseases, type 2 diabetes, etc. |
2016-09-01 |
2023-08-13 |
human |
| Lilian Calderón-Garcidueñas, Vanessa San Juan Chávez, Nora B Vacaseydel-Aceves, Raymundo Calderón-Sánchez, Edgar Macías-Escobedo, Carmen Frías, Marcela Giacometto, Luis Velasquez, Renata Félix-Villarreal, Jessie D Martin, Christopher Draheim, Randall W Engl. Chocolate, Air Pollution and Children's Neuroprotection: What Cognition Tools should be at Hand to Evaluate Interventions? Frontiers in pharmacology. vol 7. 2016-08-26. PMID:27563291. |
the established link between exposure to pm2.5, brain structural, volumetric and metabolic changes, severe cognitive deficits (1.5-2 sd from average iq) in apoe 4 heterozygous females with >75 - < 94% bmi percentiles, and the presence of alzheimer's disease (ad) hallmarks in urban children and young adults necessitates exploration of ways to protect these individuals from the deleterious neural effects of pollution exposure. |
2016-08-26 |
2023-08-13 |
Not clear |
| Bolun Li, Jie Shi, Boris A Gutman, Leslie C Baxter, Paul M Thompson, Richard J Caselli, Yalin Wan. Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study. PloS one. vol 11. issue 4. 2016-08-25. PMID:27065111. |
the apolipoprotein e (apoe) e4 genotype is a powerful risk factor for late-onset alzheimer's disease (ad). |
2016-08-25 |
2023-08-13 |
human |
| Bolun Li, Jie Shi, Boris A Gutman, Leslie C Baxter, Paul M Thompson, Richard J Caselli, Yalin Wan. Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study. PloS one. vol 11. issue 4. 2016-08-25. PMID:27065111. |
in the alzheimer's disease neuroimaging initiative (adni) cohort, we previously reported significant baseline structural differences in apoe e4 carriers relative to non-carriers, involving the left hippocampus more than the right--a difference more pronounced in e4 homozygotes than heterozygotes. |
2016-08-25 |
2023-08-13 |
human |
| Frederic Sampedro, Eduard Vilaplana, Mony J de Leon, Daniel Alcolea, Jordi Pegueroles, Victor Montal, María Carmona-Iragui, Isabel Sala, María-Belén Sánchez-Saudinos, Sofía Antón-Aguirre, Estrella Morenas-Rodríguez, Valle Camacho, Carles Falcón, Javier Pavía, Domènec Ros, Jordi Clarimón, Rafael Blesa, Alberto Lleó, Juan Forte. APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls. Oncotarget. vol 6. issue 29. 2016-08-16. PMID:26397226. |
the apoe effect on alzheimer disease (ad) risk is stronger in women than in men but its mechanisms have not been established. |
2016-08-16 |
2023-08-13 |
Not clear |
| Lei Yu, Patricia A Boyle, Sukriti Nag, Sue Leurgans, Aron S Buchman, Robert S Wilson, Zoe Arvanitakis, Jose M Farfel, Philip L De Jager, David A Bennett, Julie A Schneide. APOE and cerebral amyloid angiopathy in community-dwelling older persons. Neurobiology of aging. vol 36. issue 11. 2016-08-15. PMID:26341746. |
we aim to elucidate the relationship of the apolipoprotein e (apoe) genotypes with amyloid angiopathy in the presence of variable amounts of alzheimer's pathology. |
2016-08-15 |
2023-08-13 |
human |
| Lei Yu, Patricia A Boyle, Sukriti Nag, Sue Leurgans, Aron S Buchman, Robert S Wilson, Zoe Arvanitakis, Jose M Farfel, Philip L De Jager, David A Bennett, Julie A Schneide. APOE and cerebral amyloid angiopathy in community-dwelling older persons. Neurobiology of aging. vol 36. issue 11. 2016-08-15. PMID:26341746. |
we examined the associations of apoe with amyloid angiopathy using ordinal logistic regression analyses, controlling for demographics and subsequently alzheimer's and other common pathologies. |
2016-08-15 |
2023-08-13 |
human |
| Lei Yu, Patricia A Boyle, Sukriti Nag, Sue Leurgans, Aron S Buchman, Robert S Wilson, Zoe Arvanitakis, Jose M Farfel, Philip L De Jager, David A Bennett, Julie A Schneide. APOE and cerebral amyloid angiopathy in community-dwelling older persons. Neurobiology of aging. vol 36. issue 11. 2016-08-15. PMID:26341746. |
we conclude that both apoe ε2 and ε4 alleles are associated with more severe cerebral amyloid angiopathy, and the direct effect of ε2 is masked by the allele's negative association with comorbid alzheimer's pathology. |
2016-08-15 |
2023-08-13 |
human |
| Kristoffer Bäckman, Erik Joas, Margda Waern, Svante Östling, Xinxin Guo, Kaj Blennow, Ingmar Skoog, Deborah R Gustafso. 37 Years of Body Mass Index and Dementia: Effect Modification by the APOE Genotype: Observations from the Prospective Population Study of Women in Gothenburg, Sweden. Journal of Alzheimer's disease : JAD. vol 48. issue 4. 2016-08-03. PMID:26402098. |
little is known about the modifying effect of the apoe genotype, a major susceptibility gene for alzheimer's disease (ad), on the bmi-dementia adult life course trajectory. |
2016-08-03 |
2023-08-13 |
Not clear |
| Lilian Calderón-Garcidueñas, Antonieta Mora-Tiscareño, Gastón Melo-Sánchez, Joel Rodríguez-Díaz, Ricardo Torres-Jardón, Martin Styner, Partha S Mukherjee, Weili Lin, Valerie Jewell. A Critical Proton MR Spectroscopy Marker of Alzheimer's Disease Early Neurodegenerative Change: Low Hippocampal NAA/Cr Ratio Impacts APOE ɛ4 Mexico City Children and Their Parents. Journal of Alzheimer's disease : JAD. vol 48. issue 4. 2016-08-03. PMID:26402110. |
a critical proton mr spectroscopy marker of alzheimer's disease early neurodegenerative change: low hippocampal naa/cr ratio impacts apoe ɛ4 mexico city children and their parents. |
2016-08-03 |
2023-08-13 |
Not clear |
| Y Y Lim, V L Villemagne, S M Laws, R H Pietrzak, P J Snyder, D Ames, K A Ellis, K Harrington, A Rembach, R N Martins, C C Rowe, C L Masters, P Maruf. APOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease. Molecular psychiatry. vol 20. issue 11. 2016-08-02. PMID:25288138. |
apoe and bdnf polymorphisms moderate amyloid β-related cognitive decline in preclinical alzheimer's disease. |
2016-08-02 |
2023-08-13 |
human |
| Kyoko Konishi, Venkat Bhat, Harrison Banner, Judes Poirier, Ridha Joober, Véronique D Bohbo. APOE2 Is Associated with Spatial Navigational Strategies and Increased Gray Matter in the Hippocampus. Frontiers in human neuroscience. vol 10. 2016-07-29. PMID:27468260. |
the apolipoprotein e (apoe) gene has a strong association with alzheimer's disease (ad). |
2016-07-29 |
2023-08-13 |
human |
| Shan Jiang, Ling Tang, Na Zhao, Wanling Yang, Yu Qiu, Hong-Zhuan Che. A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer's Disease. Frontiers in aging neuroscience. vol 8. 2016-07-27. PMID:27462267. |
a systems view of the differences between apoe ε4 carriers and non-carriers in alzheimer's disease. |
2016-07-27 |
2023-08-13 |
Not clear |
| Shan Jiang, Ling Tang, Na Zhao, Wanling Yang, Yu Qiu, Hong-Zhuan Che. A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer's Disease. Frontiers in aging neuroscience. vol 8. 2016-07-27. PMID:27462267. |
apoe ε4 is the strongest genetic risk factor for late-onset alzheimer's disease (ad) and accounts for 50-65% of late-onset ad. |
2016-07-27 |
2023-08-13 |
Not clear |
| Ingmar Skoog, Margda Waern, Paul Duberstein, Kaj Blennow, Henrik Zetterberg, Anne Börjesson-Hanson, Svante Östling, Xinxin Guo, Jürgen Kern, Deborah Gustafson, Pia Gudmundsson, Thomas Marlow, Silke Ker. A 9-year prospective population-based study on the association between the APOE*E4 allele and late-life depression in Sweden. Biological psychiatry. vol 78. issue 10. 2016-07-26. PMID:25708227. |
it is well established that there is an association between the apolipoprotein e (apoe) ε4 allele (apoe*e4) and alzheimer's disease. |
2016-07-26 |
2023-08-13 |
Not clear |