| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Merve Alaylıoğlu, Duygu Gezen-Ak, Erdinç Dursun, Başar Bilgiç, Haşmet Hanağası, Turan Ertan, Hakan Gürvit, Murat Emre, Engin Eker, Ömer Uysal, Selma Yılmaze. The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort. Journal of geriatric psychiatry and neurology. vol 29. issue 4. 2017-05-29. PMID:27076484. |
the association between clusterin and apoe polymorphisms and late-onset alzheimer disease in a turkish cohort. |
2017-05-29 |
2023-08-13 |
Not clear |
| Joel Huovinen, Sami Kastinen, Simo Komulainen, Minna Oinas, Cecilia Avellan, Janek Frantzen, Jaakko Rinne, Antti Ronkainen, Mikko Kauppinen, Kimmo Lönnrot, Markus Perola, Okko T Pyykkö, Anne M Koivisto, Anne M Remes, Hilkka Soininen, Mikko Hiltunen, Seppo Helisalmi, Mitja Kurki, Juha E Jääskeläinen, Ville Leinone. Familial idiopathic normal pressure hydrocephalus. Journal of the neurological sciences. vol 368. 2017-05-17. PMID:27538594. |
this risk was independent from diagnosed alzheimer's disease and apoe ε4 genotype. |
2017-05-17 |
2023-08-13 |
Not clear |
| Rik Ossenkoppele, Daniel R Schonhaut, Michael Schöll, Samuel N Lockhart, Nagehan Ayakta, Suzanne L Baker, James P O'Neil, Mustafa Janabi, Andreas Lazaris, Averill Cantwell, Jacob Vogel, Miguel Santos, Zachary A Miller, Brianne M Bettcher, Keith A Vossel, Joel H Kramer, Maria L Gorno-Tempini, Bruce L Miller, William J Jagust, Gil D Rabinovic. Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer's disease. Brain : a journal of neurology. vol 139. issue Pt 5. 2017-05-08. PMID:26962052. |
we included 20 patients meeting criteria for probable alzheimer's disease dementia or mild cognitive impairment due to alzheimer's disease, presenting with a variety of clinical phenotypes, and 15 amyloid-β-negative cognitively normal individuals, who underwent (18)f-av1451 (tau), (11)c-pib (amyloid-β) and (18)f-fdg (glucose metabolism) positron emission tomography, apolipoprotein e (apoe) genotyping and neuropsychological testing. |
2017-05-08 |
2023-08-13 |
human |
| Yen Ying Lim, Simon M Laws, Victor L Villemagne, Robert H Pietrzak, Tenielle Porter, David Ames, Christopher Fowler, Stephanie Rainey-Smith, Peter J Snyder, Ralph N Martins, Olivier Salvado, Pierrick Bourgeat, Christopher C Rowe, Colin L Masters, Paul Maruf. Aβ-related memory decline in APOE ε4 noncarriers: Implications for Alzheimer disease. Neurology. vol 86. issue 17. 2017-04-28. PMID:27029632. |
aβ-related memory decline in apoe ε4 noncarriers: implications for alzheimer disease. |
2017-04-28 |
2023-08-13 |
Not clear |
| Tridib Mondal, Hanliu Wang, Gregory T DeKoster, Berevan Baban, Michael L Gross, Carl Friede. ApoE: In Vitro Studies of a Small Molecule Effector. Biochemistry. vol 55. issue 18. 2017-04-28. PMID:27065061. |
apolipoprotein e4 (apoe4), one of three isoforms of apoe, is the major risk factor for developing late onset alzheimer's disease. |
2017-04-28 |
2023-08-13 |
Not clear |
| Olga Voevodskaya, Pia C Sundgren, Olof Strandberg, Henrik Zetterberg, Lennart Minthon, Kaj Blennow, Lars-Olof Wahlund, Eric Westman, Oskar Hansso. Myo-inositol changes precede amyloid pathology and relate to APOE genotype in Alzheimer disease. Neurology. vol 86. issue 19. 2017-04-28. PMID:27164711. |
myo-inositol changes precede amyloid pathology and relate to apoe genotype in alzheimer disease. |
2017-04-28 |
2023-08-13 |
Not clear |
| H Depypere, A Vierin, S Weyers, A Siebe. Alzheimer's disease, apolipoprotein E and hormone replacement therapy. Maturitas. vol 94. 2017-04-28. PMID:27823753. |
studies that have examined the link between estrogen replacement therapy, alzheimer's disease and the e4 allele of apoe are inconclusive. |
2017-04-28 |
2023-08-13 |
Not clear |
| Aneta Stachowicz, Rafał Olszanecki, Maciej Suski, Katarzyna Głombik, Agnieszka Basta-Kaim, Dariusz Adamek, Ryszard Korbu. Proteomic Analysis of Mitochondria-Enriched Fraction Isolated from the Frontal Cortex and Hippocampus of Apolipoprotein E Knockout Mice Treated with Alda-1, an Activator of Mitochondrial Aldehyde Dehydrogenase (ALDH2). International journal of molecular sciences. vol 18. issue 2. 2017-04-24. PMID:28218653. |
the role of different genotypes of apolipoprotein e (apoe) in the etiology of alzheimer's disease is widely recognized. |
2017-04-24 |
2023-08-13 |
mouse |
| Ting Lian, Wenli Hui, Xianying Li, Chao Zhang, Juanli Zhu, Rui Li, Yinsheng Wan, Yali Cu. Apolipoprotein E genotyping using PCR-GoldMag lateral flow assay and its clinical applications. Molecular medicine reports. vol 14. issue 5. 2017-04-10. PMID:27665864. |
apoe genotyping is important due to the predictive value for the development of coronary artery disease and alzheimer's disease. |
2017-04-10 |
2023-08-13 |
Not clear |
| Laura Mahoney-Sanchez, Abdel Ali Belaidi, Ashley I Bush, Scott Ayto. The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update. Journal of molecular neuroscience : MN. vol 60. issue 3. 2017-03-23. PMID:27647307. |
apoe ε3 is the most common isoform, while the ε4 isoform confers the greatest genetic risk for alzheimer's disease (ad). |
2017-03-23 |
2023-08-13 |
Not clear |
| Jinmei Luo, Junli Song, Pinning Feng, Yanhong Wang, Weiqing Long, Min Liu, Laisheng L. Elevated serum apolipoprotein E is associated with metastasis and poor prognosis of non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26873483. |
apolipoprotein e (apoe) is a factor involved in alzheimer's disease, which recently attracted great attention as an important protein related to tumorigenesis and metastasis. |
2017-02-21 |
2023-08-13 |
Not clear |
| Vincenzo De Luca, Maria Donata Orfei, Sara Gaudenzi, Carlo Caltagirone, Gianfranco Spallett. Inverse effect of the APOE epsilon4 allele in late- and early-onset Alzheimer's disease. European archives of psychiatry and clinical neuroscience. vol 266. issue 7. 2017-02-13. PMID:26714935. |
inverse effect of the apoe epsilon4 allele in late- and early-onset alzheimer's disease. |
2017-02-13 |
2023-08-13 |
human |
| Megan Heffernan, Karen A Mather, Jing Xu, Amelia A Assareh, Nicole A Kochan, Simone Reppermund, Brian Draper, Julian N Trollor, Perminder Sachdev, Henry Brodat. Alcohol Consumption and Incident Dementia: Evidence from the Sydney Memory and Ageing Study. Journal of Alzheimer's disease : JAD. vol 52. issue 2. 2017-02-13. PMID:27031466. |
this inconsistency may be partly due to an interaction with the apolipoprotein e (apoe) genotype, an established risk factor for alzheimer's dementia. |
2017-02-13 |
2023-08-13 |
Not clear |
| Kevin P Koster, Conor Smith, Ana C Valencia-Olvera, Gregory R J Thatcher, Leon M Tai, Mary Jo LaD. Rexinoids as Therapeutics for Alzheimer's Disease: Role of APOE. Current topics in medicinal chemistry. vol 17. issue 6. 2017-02-08. PMID:27320328. |
rexinoids as therapeutics for alzheimer's disease: role of apoe. |
2017-02-08 |
2023-08-13 |
mouse |
| Erdinç Dursun, Merve Alaylıoğlu, Başar Bilgiç, Haşmet Hanağası, Ebba Lohmann, Irem L Atasoy, Esin Candaş, Ömür Selin Araz, Burak Önal, Hakan Gürvit, Selma Yılmazer, Duygu Gezen-A. Vitamin D deficiency might pose a greater risk for ApoEɛ4 non-carrier Alzheimer's disease patients. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 37. issue 10. 2017-02-03. PMID:27357856. |
apoe, which is involved in the transport of cholesterol, is the most significant genetic risk factor for sporadic alzheimer's disease (ad). |
2017-02-03 |
2023-08-13 |
human |
| Carlo Abbate, Beatrice Arosio, Alessandra Cantatore, Niccolò Viti, Fabrizio Giunco, Renzo Bagarolo, Paola Nicolini, Cristina Gussago, Evelyn Ferri, Martina Casati, Paolo Dionigi Rossi, Alessandra Casè, Luigi Bergamaschini, Carlo Vergani, Daniela Mar. Familial late-onset Alzheimer's disease: description of an Italian family with four affected siblings and one case of early-onset dementia in the preceding generation. Aging clinical and experimental research. vol 28. issue 5. 2017-01-30. PMID:26014970. |
we constructed the family pedigree, evaluated mutations usually associated with early-onset alzheimer's disease (app, psen1, psen2), and assessed polymorphisms in the apolipoprotein e (apoe) gene and in cytokine genes that we had previously found to be associated with a higher risk of load (il-10, il-6, tnf-α). |
2017-01-30 |
2023-08-13 |
human |
| Silke Matura, David Prvulovic, Daniel Hartmann, Monika Scheibe, Beate Sepanski, Marius Butz, Viola Oertel-Knöchel, Christian Knöchel, Tarik Karakaya, Fabian Fußer, Elke Hattingen, Johannes Pante. Age-Related Effects of the Apolipoprotein E Gene on Brain Function. Journal of Alzheimer's disease : JAD. vol 52. issue 1. 2017-01-30. PMID:27003211. |
the apolipoprotein e (apoe) ɛ4 allele is a well-established genetic risk factor for sporadic alzheimer's disease. |
2017-01-30 |
2023-08-13 |
human |
| Ke-Liang Chen, Yi-Min Sun, Yan Zhou, Qian-Hua Zhao, Ding Ding, Qi-Hao Gu. Associations between APOE polymorphisms and seven diseases with cognitive impairment including Alzheimer's disease, frontotemporal dementia, and dementia with Lewy bodies in southeast China. Psychiatric genetics. vol 26. issue 3. 2017-01-09. PMID:26981880. |
associations between apoe polymorphisms and seven diseases with cognitive impairment including alzheimer's disease, frontotemporal dementia, and dementia with lewy bodies in southeast china. |
2017-01-09 |
2023-08-13 |
Not clear |
| Chao Ma, Yangjun Zhang, Xin Li, Yaojing Chen, Junying Zhang, Zhen Liu, Kewei Chen, Zhanjun Zhan. The TT allele of rs405509 synergizes with APOE ε4 in the impairment of cognition and its underlying default mode network in non-demented elderly. Current Alzheimer research. vol 13. issue 6. 2017-01-03. PMID:26825091. |
evidence demonstrates that the t allele of the single-nucleotide polymorphism rs405509 as the apolipoprotein e (apoe) promoter is a risk factor for alzheimer's disease (ad). |
2017-01-03 |
2023-08-13 |
Not clear |
| Nicholas G Dowell, Simon L Evans, Paul S Tofts, Sarah L King, Naji Tabet, Jennifer M Ruste. Structural and resting-state MRI detects regional brain differences in young and mid-age healthy APOE-e4 carriers compared with non-APOE-e4 carriers. NMR in biomedicine. vol 29. issue 5. 2016-12-26. PMID:26929040. |
the presence of the e4 allele of the apolipoprotein e (apoe) gene is the best-known genetic risk factor for alzheimer's disease. |
2016-12-26 |
2023-08-13 |
Not clear |