Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S Wang, L Guan, D Luo, J Liu, H Lin, X Li, X Li. Gene- Gene Interaction between PPARG and APOE Gene on Late-Onset Alzheimer's Disease: A Case- Control Study in Chinese Han Population. The journal of nutrition, health & aging. vol 21. issue 4. 2017-08-14. PMID:28346566. |
gene- gene interaction between pparg and apoe gene on late-onset alzheimer's disease: a case- control study in chinese han population. |
2017-08-14 |
2023-08-13 |
Not clear |
S Wang, L Guan, D Luo, J Liu, H Lin, X Li, X Li. Gene- Gene Interaction between PPARG and APOE Gene on Late-Onset Alzheimer's Disease: A Case- Control Study in Chinese Han Population. The journal of nutrition, health & aging. vol 21. issue 4. 2017-08-14. PMID:28346566. |
the aim was to investigate the impact of pparg and apoe gene single nucleotide polymorphisms (snps) and additional gene- gene interaction on late-onset alzheimer's disease (load) risk based on chinese han population. |
2017-08-14 |
2023-08-13 |
Not clear |
Kazuyoshi Yamauchi, Yuka Ebihara, Yasushi Kawakam. Redox status of serum apolipoprotein E and its impact on HDL cholesterol levels. Clinical biochemistry. vol 50. issue 13-14. 2017-08-14. PMID:28366823. |
apolipoprotein e (apoe) is closely involved in the pathogenesis of apoe-related diseases, such as alzheimer's disease and cardiovascular disease. |
2017-08-14 |
2023-08-13 |
Not clear |
Jianjia Fan, Shahab Zareyan, Wenchen Zhao, Yoko Shimizu, Tom A Pfeifer, Jun-Hyung Tak, Murray B Isman, Bernard Van den Hoven, Mark E Duggan, Michael W Wood, Cheryl L Wellington, Iva Kuli. Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes. PloS one. vol 11. issue 9. 2017-08-04. PMID:27598782. |
the apolipoprotein e (apoe) gene is the most highly associated susceptibility locus for late onset alzheimer's disease (ad), and augmenting the beneficial physiological functions of apoe is a proposed therapeutic strategy. |
2017-08-04 |
2023-08-13 |
mouse |
b' Yi Yang, Mats Tullberg, Kirsten Mehlig, Annika Rosengren, Kjell Tor\\xc3\\xa9n, Henrik Zetterberg, Carsten Wikkels\\xc3\\xb. The APOE Genotype in Idiopathic Normal Pressure Hydrocephalus. PloS one. vol 11. issue 7. 2017-07-31. PMID:27441602.' |
presence of the apolipoprotein e ε4 (apoe ε4) allele is associated with increased risk of alzheimer's disease (ad). |
2017-07-31 |
2023-08-13 |
Not clear |
Felix Carbonell, Alex P Zijdenbos, Donald G McLaren, Yasser Iturria-Medina, Barry J Bedel. Modulation of glucose metabolism and metabolic connectivity by β-amyloid. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 36. issue 12. 2017-07-28. PMID:27301477. |
glucose hypometabolism in the pre-clinical stage of alzheimer's disease (ad) has been primarily associated with the apoe ɛ4 genotype, rather than fibrillar β-amyloid. |
2017-07-28 |
2023-08-13 |
human |
Felix Carbonell, Alex P Zijdenbos, Donald G McLaren, Yasser Iturria-Medina, Barry J Bedel. Modulation of glucose metabolism and metabolic connectivity by β-amyloid. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 36. issue 12. 2017-07-28. PMID:27301477. |
using this continuous model, we found that both apoe ɛ4 genotype and β-amyloid burden are strongly associated with glucose hypometabolism at early stages of alzheimer's disease. |
2017-07-28 |
2023-08-13 |
human |
E R Padayachee, H Zetterberg, E Portelius, J Borén, J L Molinuevo, N Andreasen, R Cukalevski, S Linse, K Blennow, U Andreasso. Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele. Brain research. vol 1651. 2017-07-28. PMID:27653981. |
cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with alzheimer's disease and the apoe ε4 allele. |
2017-07-28 |
2023-08-13 |
human |
Luise Christine Löwe, Christian Gaser, Katja Frank. The Effect of the APOE Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease. PloS one. vol 11. issue 7. 2017-07-24. PMID:27410431. |
the effect of the apoe genotype on individual brainage in normal aging, mild cognitive impairment, and alzheimer's disease. |
2017-07-24 |
2023-08-13 |
human |
Luise Christine Löwe, Christian Gaser, Katja Frank. The Effect of the APOE Genotype on Individual BrainAGE in Normal Aging, Mild Cognitive Impairment, and Alzheimer's Disease. PloS one. vol 11. issue 7. 2017-07-24. PMID:27410431. |
we applied the brain age gap estimation (brainage) method to examine the impact of the apolipoprotein e (apoe) genotype on structural brain aging, utilizing longitudinal magnetic resonance image (mri) data of 405 subjects from the alzheimer's disease neuroimaging initiative (adni) database. |
2017-07-24 |
2023-08-13 |
human |
Alaina T Baker-Nigh, Kwasi G Mawuenyega, James G Bollinger, Vitaliy Ovod, Tom Kasten, Erin E Franklin, Fan Liao, Hong Jiang, David Holtzman, Nigel J Cairns, John C Morris, Randall J Batema. Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma. The Journal of biological chemistry. vol 291. issue 53. 2017-07-20. PMID:27793990. |
the risk of alzheimer's disease (ad) is highly dependent on apolipoprotein-e (apoe) genotype. |
2017-07-20 |
2023-08-13 |
human |
Stefanie Schreiber, Frank Schreiber, Samuel N Lockhart, Andy Horng, Alexandre Bejanin, Susan M Landau, William J Jagus. Alzheimer Disease Signature Neurodegeneration and APOE Genotype in Mild Cognitive Impairment With Suspected Non-Alzheimer Disease Pathophysiology. JAMA neurology. vol 74. issue 6. 2017-07-19. PMID:28319241. |
alzheimer disease signature neurodegeneration and apoe genotype in mild cognitive impairment with suspected non-alzheimer disease pathophysiology. |
2017-07-19 |
2023-08-13 |
Not clear |
Xiuhua Ding, Richard J Kryscio, Joshua Turner, Gregory A Jicha, Gregory Cooper, Allison Caban-Holt, Frederick A Schmitt, Erin L Abne. Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial. Journal of the American Geriatrics Society. vol 64. issue 12. 2017-07-17. PMID:27801937. |
to investigate the association between baseline sleep apnea and risk of incident dementia in the prevention of alzheimer's disease with vitamin e and selenium (preadvise) study and to explore whether the association depends on apolipoprotein e (apoe) ɛ4 allele status. |
2017-07-17 |
2023-08-13 |
Not clear |
Carola I F Janssen, Diane Jansen, Martina P C Mutsaers, Pieter J W C Dederen, Bram Geenen, Monique T Mulder, Amanda J Kiliaa. The Effect of a High-Fat Diet on Brain Plasticity, Inflammation and Cognition in Female ApoE4-Knockin and ApoE-Knockout Mice. PloS one. vol 11. issue 5. 2017-07-10. PMID:27171180. |
apolipoprotein e4 (apoe4), one of three common isoforms of apoe, is a major risk factor for late-onset alzheimer disease (ad). |
2017-07-10 |
2023-08-13 |
mouse |
Robert A Sweet, Matthew L MacDonald, Caitlin M Kirkwood, Ying Ding, Tadhg Schempf, Jackie Jones-Laughner, Julia Kofler, Milos D Ikonomovic, Oscar L Lopez, Megan E Garver, Nicholas F Fitz, Radosveta Koldamova, Nathan A Yate. Apolipoprotein E*4 (APOE*4) Genotype Is Associated with Altered Levels of Glutamate Signaling Proteins and Synaptic Coexpression Networks in the Prefrontal Cortex in Mild to Moderate Alzheimer Disease. Molecular & cellular proteomics : MCP. vol 15. issue 7. 2017-06-20. PMID:27103636. |
apolipoprotein e*4 (apoe*4) genotype is associated with altered levels of glutamate signaling proteins and synaptic coexpression networks in the prefrontal cortex in mild to moderate alzheimer disease. |
2017-06-20 |
2023-08-13 |
human |
Stephanie L Adams, Kathy Tilton, James A Kozubek, Sudha Seshadri, Ivana Delall. Subcellular Changes in Bridging Integrator 1 Protein Expression in the Cerebral Cortex During the Progression of Alzheimer Disease Pathology. Journal of neuropathology and experimental neurology. vol 75. issue 8. 2017-06-20. PMID:27346750. |
genome-wide association studies have established bin1 (bridging integrator 1) as the most significant late-onset alzheimer disease (ad) susceptibility locus after apoe we analyzed bin1 protein expression using automated immunohistochemistry on the hippocampal ca1 region in 19 patients with either no, mild, or moderate-to-marked ad pathology, who had been assessed by clinical dementia rating and cerad scores. |
2017-06-20 |
2023-08-13 |
Not clear |
E de Mendonça, E Salazar Alcalá, M Fernández-Mestr. Role of genes GSTM1, GSTT1, and MnSOD in the development of late-onset Alzheimer disease and their relationship with APOE*4. Neurologia (Barcelona, Spain). vol 31. issue 8. 2017-06-16. PMID:25542503. |
role of genes gstm1, gstt1, and mnsod in the development of late-onset alzheimer disease and their relationship with apoe*4. |
2017-06-16 |
2023-08-13 |
Not clear |
Brandalyn C Riedel, Paul M Thompson, Roberta Diaz Brinto. Age, APOE and sex: Triad of risk of Alzheimer's disease. The Journal of steroid biochemistry and molecular biology. vol 160. 2017-06-12. PMID:26969397. |
age, apoe and sex: triad of risk of alzheimer's disease. |
2017-06-12 |
2023-08-13 |
Not clear |
Brandalyn C Riedel, Paul M Thompson, Roberta Diaz Brinto. Age, APOE and sex: Triad of risk of Alzheimer's disease. The Journal of steroid biochemistry and molecular biology. vol 160. 2017-06-12. PMID:26969397. |
age, apolipoprotein e ε4 (apoe) and chromosomal sex are well-established risk factors for late-onset alzheimer's disease (load; ad). |
2017-06-12 |
2023-08-13 |
Not clear |
Brandalyn C Riedel, Paul M Thompson, Roberta Diaz Brinto. Age, APOE and sex: Triad of risk of Alzheimer's disease. The Journal of steroid biochemistry and molecular biology. vol 160. 2017-06-12. PMID:26969397. |
collectively, the data indicate complex interactions between age, apoe genotype and gender that belies a one size fits all approach and argues for a precision medicine approach that integrates across the three main risk factors for alzheimer's disease. |
2017-06-12 |
2023-08-13 |
Not clear |