| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiwei Jiang, Yin Hong, Wenyi Li, Anxin Wang, Shirui Jiang, Tianlin Jiang, Yanli Wang, Linlin Wang, Shiyi Yang, Qiwei Ren, Xinying Zou, Jun X. Chain Mediation Analysis of the Effects of Nutrition and Cognition on the Association of Apolipoprotein E ɛ4 with Neuropsychiatric Symptoms in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-10-16. PMID:37840496. |
apolipoprotein e (apoe) is the most recognized risk gene for cognitive decline and clinical progression of late-onset alzheimer's disease (ad); nonetheless, its association with neuropsychiatric symptoms (npss) remains inconclusive. |
2023-10-16 |
2023-11-08 |
Not clear |
| Neriman Eren, Susanna Gerike, Berk Üsekes, Oliver Peters, Nicoleta-Carmen Cosma, Julian Hellmann-Rege. Effects of autologous serum on TREM2 and APOE in a personalized monocyte-derived macrophage assay of late-onset Alzheimer's patients. Immunity & ageing : I & A. vol 20. issue 1. 2023-10-14. PMID:37833781. |
effects of autologous serum on trem2 and apoe in a personalized monocyte-derived macrophage assay of late-onset alzheimer's patients. |
2023-10-14 |
2023-10-15 |
Not clear |
| Mitzi M Gonzales, Gabriel Vela, Vinu Philip, Hector Trevino, Ashley LaRoche, Chen-Pin Wang, Danielle M Parent, Tiffany Kautz, Claudia L Satizabal, Jeremy Tanner, Sid O'Bryant, Gladys Maestre, Russell P Tracy, Sudha Seshadr. Demographic and Clinical Characteristics Associated With Serum GFAP Levels in an Ethnically Diverse Cohort. Neurology. vol 101. issue 15. 2023-10-14. PMID:37813589. |
the goal of this study was to examine the associations between demographics, cardiovascular risk factors, and apoe ε4 status with serum gfap levels among mexican american and non-hispanic white older adults across the continuum from cognitively unimpaired to alzheimer disease dementia. |
2023-10-14 |
2023-11-08 |
Not clear |
| Robyn A Honea, Suzanne Hunt, Rebecca J Lepping, Eric D Vidoni, Jill K Morris, Amber Watts, Elias Michaelis, Jeffrey M Burns, Russell H Swerdlo. Alzheimer's disease cortical morphological phenotypes are associated with TOMM40'523-APOE haplotypes. Neurobiology of aging. vol 132. 2023-10-07. PMID:37804609. |
both the apoe ε4 and tomm40 rs10524523 ("523") genes have been associated with risk for alzheimer's disease (ad) and neuroimaging biomarkers of ad. |
2023-10-07 |
2023-10-15 |
human |
| Ian A Windham, Sarah Cohe. The cell biology of APOE in the brain. Trends in cell biology. 2023-10-07. PMID:37805344. |
the e4 variant of apoe is a major genetic risk factor for alzheimer's disease (ad) and a multitude of other neurodegenerative diseases, yet the molecular mechanisms by which apoe4 drives disease are still unclear. |
2023-10-07 |
2023-10-15 |
mouse |
| José M Aravena, Jakyung Lee, Anna E Schwartz, Kate Nyhan, Shi-Yi Wang, Becca R Lev. Beneficial Effect of Societal Factors on APOE-ε2 and ε4 Carriers' Brain Health: A Systematic Review. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023-10-04. PMID:37792627. |
apolipoprotein-e (apoe) ε4 and ε2 are the most prevalent risk-increasing and risk-reducing genetic predictors of alzheimer's disease, respectively. |
2023-10-04 |
2023-10-07 |
Not clear |
| Chun Xu, Danqing Xiao, Brenda Bin Su, Jaime Miguel Saveron, Daniela Gamez, R Osvaldo Navia, Nianyang Wang, Upal Roy, Donald A Adjeroh, Kesheng Wan. Association of APOE gene with longitudinal changes of CSF amyloid beta and tau levels in Alzheimer's disease: racial differences. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-09-27. PMID:37759100. |
association of apoe gene with longitudinal changes of csf amyloid beta and tau levels in alzheimer's disease: racial differences. |
2023-09-27 |
2023-10-07 |
Not clear |
| Chun Xu, Danqing Xiao, Brenda Bin Su, Jaime Miguel Saveron, Daniela Gamez, R Osvaldo Navia, Nianyang Wang, Upal Roy, Donald A Adjeroh, Kesheng Wan. Association of APOE gene with longitudinal changes of CSF amyloid beta and tau levels in Alzheimer's disease: racial differences. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-09-27. PMID:37759100. |
the apolipoprotein e (apoe) ε4 allele is a risk factor for late-onset alzheimer's disease (ad). |
2023-09-27 |
2023-10-07 |
Not clear |
| Kendra L Pizzonia, Julie A Suhr, Leatha A Clark, Brian C Clar. The relation of ApoE and COMT gene-gene interactions to cognitive and motor function in community-dwelling older adults: a pilot study. Frontiers in aging neuroscience. vol 15. 2023-09-25. PMID:37744392. |
for instance, apoe is a well-known gene carrying risk for alzheimer's disease, while comt has been associated with age-related reductions in motor function. |
2023-09-25 |
2023-10-07 |
Not clear |
| Amber Watts, Stephen Haneline, Kathleen A Welsh-Bohmer, Jingtao Wu, Robert Alexander, Russell H Swerdlow, Daniel K Burns, Ann M Saunder. TOMM40 '523 Genotype Distinguishes Patterns of Cognitive Improvement for Executive Function in APOEɛ3 Homozygotes. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718796. |
tomm40 '523 has been associated with cognitive performance and risk for developing alzheimer's disease independent of the effect of apoe genotype. |
2023-09-18 |
2023-10-07 |
Not clear |
| Shanshan Wang, Suzhi Liu, Shaofa Ke, Wenjun Zhou, Tengwei Pa. APOEɛ4 Status and Plasma p-tau181 Levels May Influence Memory and Executive Function Decline in Older Adults Without Dementia. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718807. |
elevated tau phosphorylation has been linked to the apolipoprotein e (apoe) ɛ4 allele, which is considered one of the most significant genes related to alzheimer's disease (ad). |
2023-09-18 |
2023-10-07 |
Not clear |
| Pranav Preman, Amaia M Arran. A neuron-specific interaction between Alzheimer's disease risk factors SORL1, APOE, and CLU. Cell reports. vol 42. issue 9. 2023-09-14. PMID:37708025. |
a neuron-specific interaction between alzheimer's disease risk factors sorl1, apoe, and clu. |
2023-09-14 |
2023-10-07 |
Not clear |
| Yang Gao, Haitao Yu, Yanchao Liu, Zhipeng Xu, Benrong He, Honghai Liu, Yuying Wang, Yao Zhang, Yi Liang, Ying Yang, Jie Zheng, Jian-Zhi Wan. GSK-3β activation mediates apolipoprotein E4-associated cognitive impairment in type 2 diabetes mellitus: A multicenter, cross-sectional study. Journal of diabetes. 2023-09-13. PMID:37700547. |
both the activation of glycogen synthase kinase-3β (gsk-3β) and the presence of apoe ε4 genotype have been found to respectively correlate with cognitive decline in patients with type 2 diabetes mellitus (t2dm), who further show a high incidence of developing alzheimer's disease. |
2023-09-13 |
2023-10-07 |
Not clear |
| Mingyue He, Tenghong Lian, Peng Guo, Weijiao Zhang, Yanan Zhang, Yue Huang, Gaifen Liu, Huiying Guan, Jinghui Li, Dongmei Luo, Weijia Zhang, Wenjing Zhang, Jing Qi, Hao Yue, Xiaomin Wang, Wei Zhan. The roles of apolipoprotein E ε4 on neuropathology and neuroinflammation in patients with Alzheimer's disease. CNS neuroscience & therapeutics. 2023-09-12. PMID:37697966. |
to explore the roles of apolipoprotein e (apoe) ε4 on the neuropathology and neuroinflammation in alzheimer's disease (ad) patients. |
2023-09-12 |
2023-10-07 |
Not clear |
| Ziyi Zhang, William Robert Kwapong, Le Cao, Zijuan Feng, Bo Wu, Junfeng Liu, Shuting Zhan. APOE ε4 Gene Carriers Demonstrate Reduced Retinal Capillary Densities in Asymptomatic Older Adults. Journal of clinical medicine. vol 12. issue 17. 2023-09-09. PMID:37685715. |
early identification of apolipoprotein e (apoe)-related microvascular pathology will help to study the microangiopathic contribution to alzheimer's disease and provide a therapeutic target for early intervention. |
2023-09-09 |
2023-10-07 |
human |
| Tianyu Zhao, Tangsheng Zhong, Meishuang Zhang, Yang Xu, Ming Zhang, Li Che. Alzheimer's Disease: Causal Effect between Obesity and APOE Gene Polymorphisms. International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686334. |
alzheimer's disease: causal effect between obesity and apoe gene polymorphisms. |
2023-09-09 |
2023-10-07 |
Not clear |
| Wan-Chen Wen, Yi-Hui Lin, Tsai-Hui Duh, Chun-Hsien Chen, Chia-Hsien Feng, Yen-Ling Che. Fluorescence detection of apolipoprotein E gene polymorphisms based on oligonucleotide ligation and magnetic separation. Analytical methods : advancing methods and applications. 2023-09-08. PMID:37680175. |
most patients with alzheimer's disease are diagnosed with late-onset alzheimer's disease (load), with apolipoprotein e (apoe) genotypes being highly associated with the frequency of load risk. |
2023-09-08 |
2023-10-07 |
Not clear |
| Ling-Chun Huang, Mei-Yueh Lee, Ching-Fang Chien, Yang-Pei Chang, Kuan-Ying Li, Yuan-Han Yan. Age and sex differences in the association between APOE genotype and Alzheimer's disease in a Taiwan Chinese population. Frontiers in aging neuroscience. vol 15. 2023-09-08. PMID:37680541. |
age and sex differences in the association between apoe genotype and alzheimer's disease in a taiwan chinese population. |
2023-09-08 |
2023-10-07 |
Not clear |
| Xiaoqian Niu, Yuye Wang, Xiangfei Zhang, Yu Wang, Wen Shao, Leian Chen, Ziyuan Yang, Dantao Pen. Quantitative electroencephalography (qEEG), apolipoprotein A-I (APOA-I), and apolipoprotein epsilon 4 (APOE ɛ4) alleles for the diagnosis of mild cognitive impairment and Alzheimer's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-09-06. PMID:37673807. |
quantitative electroencephalography (qeeg), apolipoprotein a-i (apoa-i), and apolipoprotein epsilon 4 (apoe ɛ4) alleles for the diagnosis of mild cognitive impairment and alzheimer's disease. |
2023-09-06 |
2023-10-07 |
Not clear |
| Nicholas J Schork, Jeremy A Elma. Pathway-Specific Polygenic Risk Scores Correlate with Clinical Status and Alzheimer's Disease-Related Biomarkers. Journal of Alzheimer's disease : JAD. 2023-09-04. PMID:37661888. |
apoe is the largest genetic risk factor for alzheimer's disease (ad), but there is a substantial polygenic component. |
2023-09-04 |
2023-09-07 |
Not clear |