| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca Panitch, Nathan Sahelijo, Junming Hu, Kwangsik Nho, David A Bennett, Kathryn L Lunetta, Rhoda Au, Thor D Stein, Lindsay A Farrer, Gyungah R Ju. APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response. Translational psychiatry. vol 14. issue 1. 2024-02-29. PMID:38424036. |
apoe genotype-specific methylation patterns are linked to alzheimer disease pathology and estrogen response. |
2024-02-29 |
2024-03-03 |
Not clear |
| Rebecca Panitch, Nathan Sahelijo, Junming Hu, Kwangsik Nho, David A Bennett, Kathryn L Lunetta, Rhoda Au, Thor D Stein, Lindsay A Farrer, Gyungah R Ju. APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response. Translational psychiatry. vol 14. issue 1. 2024-02-29. PMID:38424036. |
the joint effects of apoe genotype and dna methylation on alzheimer disease (ad) risk is relatively unknown. |
2024-02-29 |
2024-03-03 |
Not clear |
| Mariana Nepomuceno, Paloma Monllor, Maria Jose Cardells, Artemis Ftara, Maria Magallon, Francisco Dasí, Mari Carmen Badia, Jose Viña, Ana Llore. Redox-associated changes in healthy individuals at risk of Alzheimer's disease. A ten-year follow-up study. Free radical biology & medicine. 2024-02-28. PMID:38417685. |
carrying an allele 4 of the apolipoprotein e (apoe) is the best-established genetic risk factor to develop alzheimer's disease (ad). |
2024-02-28 |
2024-03-02 |
Not clear |
| B Jolly, V Scari. Letter to the Editor: Alzheimer's Disease-Associated APOE ε4 Frequencies in Indian Population Genomes May Suggest Implications in Lecanemab Treatment. The journal of prevention of Alzheimer's disease. vol 11. issue 2. 2024-02-20. PMID:38374759. |
letter to the editor: alzheimer's disease-associated apoe ε4 frequencies in indian population genomes may suggest implications in lecanemab treatment. |
2024-02-20 |
2024-02-22 |
Not clear |
| Chantal M Ferguson, Samuel Hildebrand, Bruno M D C Godinho, Julianna Buchwald, Dimas Echeverria, Andrew Coles, Anastasia Grigorenko, Lorenc Vangjeli, Jacquelyn Sousa, Nicholas McHugh, Matthew Hassler, Francesco Santarelli, Michael T Heneka, Evgeny Rogaev, Anastasia Khvorov. Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-02-20. PMID:38375983. |
silencing apoe with divalent-sirnas improves amyloid burden and activates immune response pathways in alzheimer's disease. |
2024-02-20 |
2024-02-22 |
Not clear |
| Hyug-Gi Kim, Yunan Tian, Sue Min Jung, Soonchan Park, Hak Young Rhee, Chang-Woo Ryu, Geon-Ho Jahn. Predicting the apolipoprotein E ε4 allele carrier status based on gray matter volumes and cognitive function. Brain and behavior. vol 14. issue 1. 2024-02-20. PMID:38376028. |
apolipoprotein e (apoe) ε4 carriers have a higher risk of developing alzheimer's disease (ad) and show brain atrophy and cognitive decline even before diagnosis. |
2024-02-20 |
2024-02-22 |
Not clear |
| Claudia Tato-Fernández, Laura L Ekblad, Elina Pietilä, Virva Saunavaara, Semi Helin, Riitta Parkkola, Henrik Zetterberg, Kaj Blennow, Juha O Rinne, Anniina Snellma. Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET. Neurobiology of disease. 2024-02-16. PMID:38365046. |
except for aging, carrying the apoe ε4 allele (apoe4) is the most important risk factor for sporadic alzheimer's disease. |
2024-02-16 |
2024-02-19 |
human |
| Ananthan Ambikairajah, Mizanur Khondoker, Edward Morris, Ann-Marie G de Lange, Rasha N M Saleh, Anne Marie Minihane, Michael Hornberge. Investigating the synergistic effects of hormone replacement therapy, apolipoprotein E and age on brain health in the UK Biobank. Human brain mapping. vol 45. issue 2. 2024-02-10. PMID:38339898. |
yet, the role of sex-specific risk factors during midlife, including hormone replacement therapy (hrt) and their interaction with other major risk factors for alzheimer's disease, such as apolipoprotein e (apoe)-e4 genotype and age, on brain health remains unclear. |
2024-02-10 |
2024-02-12 |
human |
| Ian A Windham, Alex E Powers, Joey V Ragusa, E Diane Wallace, Maria Clara Zanellati, Victoria H Williams, Colby H Wagner, Kristen K White, Sarah Cohe. APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size. The Journal of cell biology. vol 223. issue 4. 2024-02-09. PMID:38334983. |
the e4 variant of apoe strongly predisposes individuals to late-onset alzheimer's disease. |
2024-02-09 |
2024-02-11 |
Not clear |
| Ana-Caroline Raulin, Sydney V Doss, Michael G Heckman, Emily C Craver, Zonghua Li, Tadafumi C Ikezu, Hiroaki Sekiya, Chia-Chen Liu, Yuka A Martens, Cassandra L Rosenberg, Lindsey A Kuchenbecker, Michael DeTure, R Ross Reichard, Aivi T Nguyen, Eleni Constantopoulos, Rachel A Larsen, Emmaline K Kounaves, Melissa E Murray, Dennis W Dickson, Ronald C Petersen, Guojun Bu, Takahisa Kanekiy. Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease. Acta neuropathologica communications. vol 12. issue 1. 2024-02-09. PMID:38336940. |
impact of apoe on amyloid and tau accumulation in argyrophilic grain disease and alzheimer's disease. |
2024-02-09 |
2024-02-12 |
Not clear |
| Lauren Edwards, Kelsey R Thomas, Alexandra J Weigand, Emily C Edmonds, Alexandra L Clark, Einat K Brenner, Sarah J Banks, Paul E Gilbert, Daniel A Nation, Lisa Delano-Wood, Mark W Bondi, Katherine J Bange. Pulse pressure and APOE ε4 dose interact to affect cerebral blood flow in older adults without dementia. Cerebral circulation - cognition and behavior. vol 6. 2024-02-08. PMID:38328026. |
144 older adults without dementia from the alzheimer's disease neuroimaging initiative underwent arterial spin labeling and t1-weighted mri, apoe genotyping, fluorodeoxyglucose positron emission tomography (fdg-pet), lumbar puncture, and blood pressure (bp) assessment. |
2024-02-08 |
2024-02-10 |
human |
| Gillian K Carling, Li Fan, Nessa R Foxe, Kendra Norman, Pearly Ye, Man Ying Wong, Daphne Zhu, Fangmin Yu, Jielin Xu, Allan Yarahmady, Hao Chen, Yige Huang, Sadaf Amin, Emmanouil Zacharioudakis, Xiaoying Chen, David M Holtzman, Sue-Ann Mok, Evripidis Gavathiotis, Subhash C Sinha, Feixiong Cheng, Wenjie Luo, Shiaoching Gong, Li Ga. Alzheimer's disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328219. |
the strongest risk factors for alzheimer's disease (ad) include the χ4 allele of apolipoprotein e (apoe), the |
2024-02-08 |
2024-02-10 |
Not clear |
| Guillermo Santos-Sánchez, Eduardo Ponce-España, Ana Isabel Álvarez-López, Justo Pedroche, María Del Carmen Millán-Linares, María-Soledad Fernández-Pachón, Patricia Judith Lardone, Ivan Cruz-Chamorro, Antonio Carrillo-Vic. A lupin protein hydrolysate protects the central nervous system from oxidative stress in WD-fed ApoE Molecular nutrition & food research. 2024-02-03. PMID:38308501. |
a lupin protein hydrolysate protects the central nervous system from oxidative stress in wd-fed apoe oxidative stress plays a crucial role in neurodegenerative diseases like parkinson's and alzheimer's. |
2024-02-03 |
2024-02-05 |
human |
| Augustine Chemparathy, Yann Le Guen, Sunny Chen, Eun-Gyung Lee, Lesley Leong, John E Gorzynski, Tanner D Jensen, Alexis Ferrasse, Guangxue Xu, Hong Xiang, Michael E Belloy, Nandita Kasireddy, Andrés Peña-Tauber, Kennedy Williams, Ilaria Stewart, Lia Talozzi, Thomas S Wingo, James J Lah, Suman Jayadev, Chadwick M Hales, Elaine Peskind, Daniel D Child, Sigrun Roeber, C Dirk Keene, Le Cong, Euan A Ashley, Chang-En Yu, Michael D Greiciu. APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology. Neuron. 2024-02-01. PMID:38301647. |
apoe loss-of-function variants: compatible with longevity and associated with resistance to alzheimer's disease pathology. |
2024-02-01 |
2024-02-04 |
Not clear |
| Augustine Chemparathy, Yann Le Guen, Sunny Chen, Eun-Gyung Lee, Lesley Leong, John E Gorzynski, Tanner D Jensen, Alexis Ferrasse, Guangxue Xu, Hong Xiang, Michael E Belloy, Nandita Kasireddy, Andrés Peña-Tauber, Kennedy Williams, Ilaria Stewart, Lia Talozzi, Thomas S Wingo, James J Lah, Suman Jayadev, Chadwick M Hales, Elaine Peskind, Daniel D Child, Sigrun Roeber, C Dirk Keene, Le Cong, Euan A Ashley, Chang-En Yu, Michael D Greiciu. APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology. Neuron. 2024-02-01. PMID:38301647. |
the ε4 allele of apolipoprotein e (apoe) is the strongest genetic risk factor for sporadic alzheimer's disease (ad). |
2024-02-01 |
2024-02-04 |
Not clear |
| Veronika Matuskova, Katerina Veverova, Dylan J Jester, Vaclav Matoska, Zahinoor Ismail, Katerina Sheardova, Hana Horakova, Jiri Cerman, Jan Laczó, Ross Andel, Jakub Hort, Martin Vyhnale. Mild behavioral impairment in early Alzheimer's disease and its association with APOE and BDNF risk genetic polymorphisms. Alzheimer's research & therapy. vol 16. issue 1. 2024-01-26. PMID:38279143. |
mild behavioral impairment in early alzheimer's disease and its association with apoe and bdnf risk genetic polymorphisms. |
2024-01-26 |
2024-01-29 |
human |
| Michael R Strickland, Michael J Rau, Brock Summers, Katherine Basore, John Wulf, Hong Jiang, Yun Chen, Jason D Ulrich, Gwendalyn J Randolph, Rui Zhang, James A J Fitzpatrick, Anil G Cashikar, David M Holtzma. Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins. Neuron. 2024-01-24. PMID:38266643. |
the apolipoprotein e gene (apoe) is of great interest due to its role as a risk factor for late-onset alzheimer's disease. |
2024-01-24 |
2024-01-27 |
Not clear |
| Lucas Trevizani Rasmussen, Roger Willian de Labio, Mônica Pezenatto Dos Santos, Bruno Mari Fredi, Eduardo Federighi Baisi Chagas, Elizabeth Suchi Chen, Gustavo Turecki, Marília de Arruda Cardoso Smith, Spencer Luiz Marques Payã. Changes in Expression of Key Genes in Alzheimer's Disease: A Specific Brain Tissue Change. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024-01-24. PMID:38267766. |
in the present study, the expression of ten genes (app, ps1 and ps2, apoe, apba2, lrp1, grin2b, insr, gjb1, and ide) involved in the main pathways related to alzheimer's disease were analyzed in auditory cortices and cerebellum from 29 ad patients and 29 healthy older adult. |
2024-01-24 |
2024-01-27 |
Not clear |
| Valborg Gudmundsdottir, Elisabet Frick, Valur Emilsson, Thorarinn Jonmundsson, Anna Steindorsdottir, Erik C B Johnson, Raquel Puerta, Eric Dammer, Anantharaman Shantaraman, Amanda Cano, Merce Boada, Sergi Valero, Pablo Garcia-Gonzalez, Elias Gudmundsson, Alexander Gudjonsson, Rebecca Pitts, Xiazi Qiu, Nancy Finkel, Joseph Loureiro, Anthony Orth, Nicholas Seyfried, Allan Levey, Agustín Ruiz, Thor Aspelund, Lori Jennings, Lenore Launer, Vilmundur Gudnaso. Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease. Research square. 2024-01-23. PMID:38260284. |
serum proteomics reveals apoe dependent and independent protein signatures in alzheimer's disease. |
2024-01-23 |
2024-01-25 |
Not clear |
| Cassandra Morrison, Michael D Oliver, Virginia Berry, Farooq Kamal, Mahsa Dada. The influence of APOE status on rate of cognitive decline. GeroScience. 2024-01-22. PMID:38253819. |
apolipoprotein (apoe) ɛ4 positivity and subjective cognitive decline (scd) both increase risk of alzheimer's disease (ad) development. |
2024-01-22 |
2024-01-25 |
Not clear |