All Relations between Alzheimer Disease and apoe

Publication Sentence Publish Date Extraction Date Species
Michael E Belloy, Shea J Andrews, Yann Le Guen, Michael Cuccaro, Lindsay A Farrer, Valerio Napolioni, Michael D Greiciu. APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry. JAMA neurology. 2023-11-06. PMID:37930705. apoe genotype and alzheimer disease risk across age, sex, and population ancestry. 2023-11-06 2023-11-08 Not clear
Michael E Belloy, Shea J Andrews, Yann Le Guen, Michael Cuccaro, Lindsay A Farrer, Valerio Napolioni, Michael D Greiciu. APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry. JAMA neurology. 2023-11-06. PMID:37930705. apolipoprotein e (apoe)*2 and apoe*4 are, respectively, the strongest protective and risk-increasing, common genetic variants for late-onset alzheimer disease (ad), making apoe status highly relevant toward clinical trial design and ad research broadly. 2023-11-06 2023-11-08 Not clear
Xin Zhang, Tian Yuan, Xuhui Chen, Xuebo Liu, Jun Hu, Zhigang Li. Effects of DHA on cognitive dysfunction in aging and Alzheimer's disease: The mediating roles of ApoE. Progress in lipid research. vol 93. 2023-11-03. PMID:37890592. effects of dha on cognitive dysfunction in aging and alzheimer's disease: the mediating roles of apoe. 2023-11-03 2023-11-08 Not clear
Deebika Balu, Ana C Valencia-Olvera, Austin Nguyen, Mehul Patnam, Jason York, Francesco Peri, Frank Neumann, Mary Jo LaDu, Leon M Ta. A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice. Alzheimer's research & therapy. vol 15. issue 1. 2023-10-20. PMID:37858252. apoe genotype is the greatest genetic risk factor for sporadic alzheimer's disease (ad). 2023-10-20 2023-11-08 mouse
Yuexuan Xu, Zhongxuan Sun, Erin Jonaitis, Yuetiva Deming, Qiongshi Lu, Sterling C Johnson, Corinne D Engelma. Apolipoprotein E moderates the association between non-APOE polygenic risk score for Alzheimer's disease and aging on preclinical cognitive function. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-10-20. PMID:37858606. variation in preclinical cognitive decline suggests additional genetic factors related to alzheimer's disease (eg, a non-apoe polygenic risk score [prs]) may interact with the apoe ε4 allele to influence cognitive decline. 2023-10-20 2023-11-08 Not clear
Anqi Li, Jing Du, Yue Cai, Xuhui Chen, Kun Sun, Tengfei Gu. Body Mass Index Decrease Has a Distinct Association with Alzheimer's Disease Pathophysiology in APOE ɛ4 Carriers and Non-Carriers. Journal of Alzheimer's disease : JAD. 2023-10-16. PMID:37840490. body mass index decrease has a distinct association with alzheimer's disease pathophysiology in apoe ɛ4 carriers and non-carriers. 2023-10-16 2023-11-08 Not clear
Anqi Li, Jing Du, Yue Cai, Xuhui Chen, Kun Sun, Tengfei Gu. Body Mass Index Decrease Has a Distinct Association with Alzheimer's Disease Pathophysiology in APOE ɛ4 Carriers and Non-Carriers. Journal of Alzheimer's disease : JAD. 2023-10-16. PMID:37840490. body mass index (bmi) changes may be related to alzheimer's disease (ad) alterations, but it is unclear how the apolipoprotein e ɛ4 (apoe ɛ4) allele affects their association. 2023-10-16 2023-11-08 Not clear
Jiwei Jiang, Yin Hong, Wenyi Li, Anxin Wang, Shirui Jiang, Tianlin Jiang, Yanli Wang, Linlin Wang, Shiyi Yang, Qiwei Ren, Xinying Zou, Jun X. Chain Mediation Analysis of the Effects of Nutrition and Cognition on the Association of Apolipoprotein E ɛ4 with Neuropsychiatric Symptoms in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-10-16. PMID:37840496. apolipoprotein e (apoe) is the most recognized risk gene for cognitive decline and clinical progression of late-onset alzheimer's disease (ad); nonetheless, its association with neuropsychiatric symptoms (npss) remains inconclusive. 2023-10-16 2023-11-08 Not clear
Neriman Eren, Susanna Gerike, Berk Üsekes, Oliver Peters, Nicoleta-Carmen Cosma, Julian Hellmann-Rege. Effects of autologous serum on TREM2 and APOE in a personalized monocyte-derived macrophage assay of late-onset Alzheimer's patients. Immunity & ageing : I & A. vol 20. issue 1. 2023-10-14. PMID:37833781. effects of autologous serum on trem2 and apoe in a personalized monocyte-derived macrophage assay of late-onset alzheimer's patients. 2023-10-14 2023-10-15 Not clear
Mitzi M Gonzales, Gabriel Vela, Vinu Philip, Hector Trevino, Ashley LaRoche, Chen-Pin Wang, Danielle M Parent, Tiffany Kautz, Claudia L Satizabal, Jeremy Tanner, Sid O'Bryant, Gladys Maestre, Russell P Tracy, Sudha Seshadr. Demographic and Clinical Characteristics Associated With Serum GFAP Levels in an Ethnically Diverse Cohort. Neurology. vol 101. issue 15. 2023-10-14. PMID:37813589. the goal of this study was to examine the associations between demographics, cardiovascular risk factors, and apoe ε4 status with serum gfap levels among mexican american and non-hispanic white older adults across the continuum from cognitively unimpaired to alzheimer disease dementia. 2023-10-14 2023-11-08 Not clear
Robyn A Honea, Suzanne Hunt, Rebecca J Lepping, Eric D Vidoni, Jill K Morris, Amber Watts, Elias Michaelis, Jeffrey M Burns, Russell H Swerdlo. Alzheimer's disease cortical morphological phenotypes are associated with TOMM40'523-APOE haplotypes. Neurobiology of aging. vol 132. 2023-10-07. PMID:37804609. both the apoe ε4 and tomm40 rs10524523 ("523") genes have been associated with risk for alzheimer's disease (ad) and neuroimaging biomarkers of ad. 2023-10-07 2023-10-15 human
Ian A Windham, Sarah Cohe. The cell biology of APOE in the brain. Trends in cell biology. 2023-10-07. PMID:37805344. the e4 variant of apoe is a major genetic risk factor for alzheimer's disease (ad) and a multitude of other neurodegenerative diseases, yet the molecular mechanisms by which apoe4 drives disease are still unclear. 2023-10-07 2023-10-15 mouse
José M Aravena, Jakyung Lee, Anna E Schwartz, Kate Nyhan, Shi-Yi Wang, Becca R Lev. Beneficial Effect of Societal Factors on APOE-ε2 and ε4 Carriers' Brain Health: A Systematic Review. The journals of gerontology. Series A, Biological sciences and medical sciences. 2023-10-04. PMID:37792627. apolipoprotein-e (apoe) ε4 and ε2 are the most prevalent risk-increasing and risk-reducing genetic predictors of alzheimer's disease, respectively. 2023-10-04 2023-10-07 Not clear
Chun Xu, Danqing Xiao, Brenda Bin Su, Jaime Miguel Saveron, Daniela Gamez, R Osvaldo Navia, Nianyang Wang, Upal Roy, Donald A Adjeroh, Kesheng Wan. Association of APOE gene with longitudinal changes of CSF amyloid beta and tau levels in Alzheimer's disease: racial differences. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-09-27. PMID:37759100. association of apoe gene with longitudinal changes of csf amyloid beta and tau levels in alzheimer's disease: racial differences. 2023-09-27 2023-10-07 Not clear
Chun Xu, Danqing Xiao, Brenda Bin Su, Jaime Miguel Saveron, Daniela Gamez, R Osvaldo Navia, Nianyang Wang, Upal Roy, Donald A Adjeroh, Kesheng Wan. Association of APOE gene with longitudinal changes of CSF amyloid beta and tau levels in Alzheimer's disease: racial differences. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-09-27. PMID:37759100. the apolipoprotein e (apoe) ε4 allele is a risk factor for late-onset alzheimer's disease (ad). 2023-09-27 2023-10-07 Not clear
Kendra L Pizzonia, Julie A Suhr, Leatha A Clark, Brian C Clar. The relation of ApoE and COMT gene-gene interactions to cognitive and motor function in community-dwelling older adults: a pilot study. Frontiers in aging neuroscience. vol 15. 2023-09-25. PMID:37744392. for instance, apoe is a well-known gene carrying risk for alzheimer's disease, while comt has been associated with age-related reductions in motor function. 2023-09-25 2023-10-07 Not clear
Amber Watts, Stephen Haneline, Kathleen A Welsh-Bohmer, Jingtao Wu, Robert Alexander, Russell H Swerdlow, Daniel K Burns, Ann M Saunder. TOMM40 '523 Genotype Distinguishes Patterns of Cognitive Improvement for Executive Function in APOEɛ3 Homozygotes. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718796. tomm40 '523 has been associated with cognitive performance and risk for developing alzheimer's disease independent of the effect of apoe genotype. 2023-09-18 2023-10-07 Not clear
Shanshan Wang, Suzhi Liu, Shaofa Ke, Wenjun Zhou, Tengwei Pa. APOEɛ4 Status and Plasma p-tau181 Levels May Influence Memory and Executive Function Decline in Older Adults Without Dementia. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718807. elevated tau phosphorylation has been linked to the apolipoprotein e (apoe) ɛ4 allele, which is considered one of the most significant genes related to alzheimer's disease (ad). 2023-09-18 2023-10-07 Not clear
Pranav Preman, Amaia M Arran. A neuron-specific interaction between Alzheimer's disease risk factors SORL1, APOE, and CLU. Cell reports. vol 42. issue 9. 2023-09-14. PMID:37708025. a neuron-specific interaction between alzheimer's disease risk factors sorl1, apoe, and clu. 2023-09-14 2023-10-07 Not clear
Yang Gao, Haitao Yu, Yanchao Liu, Zhipeng Xu, Benrong He, Honghai Liu, Yuying Wang, Yao Zhang, Yi Liang, Ying Yang, Jie Zheng, Jian-Zhi Wan. GSK-3β activation mediates apolipoprotein E4-associated cognitive impairment in type 2 diabetes mellitus: A multicenter, cross-sectional study. Journal of diabetes. 2023-09-13. PMID:37700547. both the activation of glycogen synthase kinase-3β (gsk-3β) and the presence of apoe ε4 genotype have been found to respectively correlate with cognitive decline in patients with type 2 diabetes mellitus (t2dm), who further show a high incidence of developing alzheimer's disease. 2023-09-13 2023-10-07 Not clear