Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Junlin Shen, Wen Qin, Qiang Xu, Lixue Xu, Jiayuan Xu, Peng Zhang, Huaigui Liu, Bing Liu, Tianzi Jiang, Chunshui Y. Modulation of APOE and SORL1 genes on hippocampal functional connectivity in healthy young adults. Brain structure & function. vol 222. issue 6. 2018-01-30. PMID:28229235. |
apolipoprotein e (apoe) and sortilin-related receptor (sorl1) genes act on the same metabolic pathway and have been associated with alzheimer's disease (ad) characterized by hippocampal impairment. |
2018-01-30 |
2023-08-13 |
human |
Bárbara R Cardoso, Dominic J Hare, Monica Lind, Catriona A McLean, Irene Volitakis, Simon M Laws, Colin L Masters, Ashley I Bush, Blaine R Robert. The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease. ACS chemical neuroscience. vol 8. issue 7. 2018-01-30. PMID:28453930. |
the apoe ε4 allele is associated with lower selenium levels in the brain: implications for alzheimer's disease. |
2018-01-30 |
2023-08-13 |
Not clear |
Bárbara R Cardoso, Dominic J Hare, Monica Lind, Catriona A McLean, Irene Volitakis, Simon M Laws, Colin L Masters, Ashley I Bush, Blaine R Robert. The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease. ACS chemical neuroscience. vol 8. issue 7. 2018-01-30. PMID:28453930. |
our findings suggest a relevant interaction between apoe ε4 and selenium delivery into brain, and show changes in cellular selenium distribution in the alzheimer's disease brain. |
2018-01-30 |
2023-08-13 |
Not clear |
Michelle Perkins, Andrew B Wolf, Bernardo Chavira, Daniel Shonebarger, J P Meckel, Lana Leung, Lauren Ballina, Sarah Ly, Aman Saini, T Bucky Jones, Johana Vallejo, Garilyn Jentarra, Jon Vall. Altered Energy Metabolism Pathways in the Posterior Cingulate in Young Adult Apolipoprotein E ɛ4 Carriers. Journal of Alzheimer's disease : JAD. vol 53. issue 1. 2018-01-29. PMID:27128370. |
the apoe gene, encoding apolipoprotein e, is the primary genetic risk factor for late-onset alzheimer's disease (ad). |
2018-01-29 |
2023-08-13 |
Not clear |
Katherine J Bangen, Jayandra J Himali, Alexa S Beiser, Daniel A Nation, David J Libon, Caroline S Fox, Sudha Seshadri, Philip A Wolf, Ann C McKee, Rhoda Au, Lisa Delano-Woo. Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. vol 53. issue 4. 2018-01-29. PMID:27392855. |
interaction between midlife blood glucose and apoe genotype predicts later alzheimer's disease pathology. |
2018-01-29 |
2023-08-13 |
human |
Katherine J Bangen, Jayandra J Himali, Alexa S Beiser, Daniel A Nation, David J Libon, Caroline S Fox, Sudha Seshadri, Philip A Wolf, Ann C McKee, Rhoda Au, Lisa Delano-Woo. Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. vol 53. issue 4. 2018-01-29. PMID:27392855. |
we examined the impact of apoe genotype and midlife blood glucose on post-mortem vascular and alzheimer's disease (ad) neuropathology. |
2018-01-29 |
2023-08-13 |
human |
Monika Mandecka, Magdalena Budziszewska, Anna Barczak, Beata Pepłońska, Małgorzata Chodakowska-Żebrowska, Anna Filipek-Gliszczyńska, Marta Nesteruk, Maria Styczyńska, Maria Barcikowska, Tomasz Gabryelewic. Association between Cerebrospinal Fluid Biomarkers for Alzheimer's Disease, APOE Genotypes and Auditory Verbal Learning Task in Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 1. 2018-01-29. PMID:27472875. |
association between cerebrospinal fluid biomarkers for alzheimer's disease, apoe genotypes and auditory verbal learning task in subjective cognitive decline, mild cognitive impairment, and alzheimer's disease. |
2018-01-29 |
2023-08-13 |
Not clear |
Monika Mandecka, Magdalena Budziszewska, Anna Barczak, Beata Pepłońska, Małgorzata Chodakowska-Żebrowska, Anna Filipek-Gliszczyńska, Marta Nesteruk, Maria Styczyńska, Maria Barcikowska, Tomasz Gabryelewic. Association between Cerebrospinal Fluid Biomarkers for Alzheimer's Disease, APOE Genotypes and Auditory Verbal Learning Task in Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 1. 2018-01-29. PMID:27472875. |
the aim of this study was to estimate the prevalence of ad csf biomarkers in those individuals with a subjective cognitive decline (scd), a mild cognitive impairment (mci), and alzheimer's dementia (ad-d), together with the relationships between the biomarkers, an apoe ɛ4 presence, and a verbal episodic memory performance. |
2018-01-29 |
2023-08-13 |
Not clear |
Jiu Chen, Hao Shu, Zan Wang, Duan Liu, Yongmei Shi, Lin Xu, Zhijun Zhan. Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer's disease. Oncotarget. vol 7. issue 37. 2018-01-29. PMID:27542235. |
protective effect of apoe epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for alzheimer's disease. |
2018-01-29 |
2023-08-13 |
Not clear |
Jiu Chen, Hao Shu, Zan Wang, Duan Liu, Yongmei Shi, Lin Xu, Zhijun Zhan. Protective effect of APOE epsilon 2 on intrinsic functional connectivity of the entorhinal cortex is associated with better episodic memory in elderly individuals with risk factors for Alzheimer's disease. Oncotarget. vol 7. issue 37. 2018-01-29. PMID:27542235. |
the apolipoprotein e (apoe) ε4 allele associates with accelerating the conversion from amnestic mild cognitive impairment (amci) to alzheimer's disease (ad), whereas the protectiveapoeε2 allele appears to be against the disease. |
2018-01-29 |
2023-08-13 |
Not clear |
Won-Suk Chung, Philip B Verghese, Chandrani Chakraborty, Julia Joung, Bradley T Hyman, Jason D Ulrich, David M Holtzman, Ben A Barre. Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 36. 2018-01-29. PMID:27559087. |
the strongest genetic risk factor influencing susceptibility to late-onset alzheimer's disease (ad) is apolipoprotein e (apoe) genotype. |
2018-01-29 |
2023-08-13 |
Not clear |
Sarah K Woody, Helen Zhou, Shaher Ibrahimi, Yafeng Dong, Liqin Zha. Human ApoE ɛ2 Promotes Regulatory Mechanisms of Bioenergetic and Synaptic Function in Female Brain: A Focus on V-type H+-ATPase. Journal of Alzheimer's disease : JAD. vol 53. issue 3. 2018-01-26. PMID:27340853. |
it is established that the three apoe isoforms confer differential susceptibility to alzheimer's disease (ad); however, an in-depth molecular understanding of the underlying mechanisms is currently unavailable. |
2018-01-26 |
2023-08-13 |
mouse |
Eun Hyun Seo, Sang Hoon Kim, Sang Hag Park, Seong-Ho Kang, Il Han Cho. Topographical APOE ɛ4 Genotype Influence on Cerebral Metabolism in the Continuum of Alzheimer's Disease: Amyloid Burden Adjusted Analysis. Journal of Alzheimer's disease : JAD. vol 54. issue 2. 2018-01-26. PMID:27567846. |
topographical apoe ɛ4 genotype influence on cerebral metabolism in the continuum of alzheimer's disease: amyloid burden adjusted analysis. |
2018-01-26 |
2023-08-13 |
Not clear |
Eun Hyun Seo, Sang Hoon Kim, Sang Hag Park, Seong-Ho Kang, Il Han Cho. Topographical APOE ɛ4 Genotype Influence on Cerebral Metabolism in the Continuum of Alzheimer's Disease: Amyloid Burden Adjusted Analysis. Journal of Alzheimer's disease : JAD. vol 54. issue 2. 2018-01-26. PMID:27567846. |
apoe ɛ4 contributes to alzheimer's disease (ad) pathogenesis by amyloid-beta (aβ)-dependent and aβ-independent processes. |
2018-01-26 |
2023-08-13 |
Not clear |
Baoyu Yuan, Chunming Xie, Hao Shu, Wenxiang Liao, Zan Wang, Duan Liu, Zhijun Zhan. Differential Effects of APOE Genotypes on the Anterior and Posterior Subnetworks of Default Mode Network in Amnestic Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD. vol 54. issue 4. 2018-01-24. PMID:27589521. |
the apolipoprotein e (apoe) ɛ4 carriers are at increased risk of developing alzheimer's disease (ad) while the ɛ2 carriers appear to be protected against the disease. |
2018-01-24 |
2023-08-13 |
Not clear |
João Massano, Miguel Leão, Carolina Garret. [Investigation of Genetic Etiology in Neurodegenerative Dementias: Recommendations from the Centro Hospitalar São João Neurogenetics Group]. Acta medica portuguesa. vol 29. issue 10. 2018-01-23. PMID:28103467. |
apoe genotyping is not recommended for the diagnostic or genetic counseling purposes in alzheimer disease. |
2018-01-23 |
2023-08-13 |
Not clear |
Richard J Caselli, Amylou C Dueck, Dona E C Locke, Bruce R Henslin, Travis A Johnson, Bryan K Woodruff, Charlene Hoffman-Snyder, Yonas E Ged. Impact of Personality on Cognitive Aging: A Prospective Cohort Study. Journal of the International Neuropsychological Society : JINS. vol 22. issue 7. 2018-01-19. PMID:27346168. |
the aim of this study was to assess the association between personality factors and age-related longitudinal cognitive performance, and explore interactions of stress-proneness with apolipoprotein e (apoe) ɛ4, a prevalent risk factor for alzheimer's disease (ad). |
2018-01-19 |
2023-08-13 |
Not clear |
Tingting Xiao, Bin Jiao, Weiwei Zhang, Beisha Tang, Lu She. Effect of the CYP2D6 and APOE Polymorphisms on the Efficacy of Donepezil in Patients with Alzheimer's Disease: A Systematic Review and Meta-Analysis. CNS drugs. vol 30. issue 10. 2018-01-17. PMID:27282366. |
effect of the cyp2d6 and apoe polymorphisms on the efficacy of donepezil in patients with alzheimer's disease: a systematic review and meta-analysis. |
2018-01-17 |
2023-08-13 |
Not clear |
Ying Liu, Lan Tan, Hui-Fu Wang, Yong Liu, Xiao-Ke Hao, Chen-Chen Tan, Teng Jiang, Bing Liu, Dao-Qiang Zhang, Jin-Tai Y. Multiple Effect of APOE Genotype on Clinical and Neuroimaging Biomarkers Across Alzheimer's Disease Spectrum. Molecular neurobiology. vol 53. issue 7. 2018-01-16. PMID:26298664. |
multiple effect of apoe genotype on clinical and neuroimaging biomarkers across alzheimer's disease spectrum. |
2018-01-16 |
2023-08-13 |
human |
Ying Liu, Lan Tan, Hui-Fu Wang, Yong Liu, Xiao-Ke Hao, Chen-Chen Tan, Teng Jiang, Bing Liu, Dao-Qiang Zhang, Jin-Tai Y. Multiple Effect of APOE Genotype on Clinical and Neuroimaging Biomarkers Across Alzheimer's Disease Spectrum. Molecular neurobiology. vol 53. issue 7. 2018-01-16. PMID:26298664. |
the apolipoprotein e ε4 (apoe ε4) allele is the most important genetic risk factor for alzheimer's disease (ad); however, the underlying mechanisms responsible for it remain controversial. |
2018-01-16 |
2023-08-13 |
human |