| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| José V Pardo, Joel T Le. Atypical Localization and Dissociation between Glucose Uptake and Amyloid Deposition in Cognitively Normal APOE*E4 Homozygotic Elders Compared with Patients with Late-Onset Alzheimer's Disease. eNeuro. vol 5. issue 1. 2019-01-29. PMID:29497704. |
atypical localization and dissociation between glucose uptake and amyloid deposition in cognitively normal apoe*e4 homozygotic elders compared with patients with late-onset alzheimer's disease. |
2019-01-29 |
2023-08-13 |
Not clear |
| Marco Túlio Gualberto Cintra, Rafaela Teixeira Ávila, Thayana Oliveira Soares, Luciana Cristina Matos Cunha, Katia Daniela Silveira, Edgar Nunes de Moraes, Kaique Roger Simas, Renato Bragança Fernandes, Denise Utsch Gonçalves, Nilton Alves de Rezende, Maria Aparecida Camargos Bicalh. Increased N200 and P300 latencies in cognitively impaired elderly carrying ApoE ε-4 allele. International journal of geriatric psychiatry. vol 33. issue 2. 2019-01-25. PMID:28833437. |
to compare the results of neuropsychological tests, evoked potentials n200 and p300 and polymorphisms of apoe and bdnf rs6265 between patients with normal cognition and those with mild cognitive impairment (mci) and alzheimer's dementia (ad). |
2019-01-25 |
2023-08-13 |
Not clear |
| Jurgita Zekonyte, Kenji Sakai, James A R Nicoll, Roy O Weller, Roxana O Carar. Quantification of molecular interactions between ApoE, amyloid-beta (Aβ) and laminin: Relevance to accumulation of Aβ in Alzheimer's disease. Biochimica et biophysica acta. vol 1862. issue 5. 2019-01-24. PMID:26327683. |
quantification of molecular interactions between apoe, amyloid-beta (aβ) and laminin: relevance to accumulation of aβ in alzheimer's disease. |
2019-01-24 |
2023-08-13 |
mouse |
| Jaeho Kim, Seongbeom Park, Heejin Yoo, Hyemin Jang, Yeshin Kim, Ko Woon Kim, Young Kyoung Jang, Jin San Lee, Sung Tae Kim, Seonwoo Kim, Jong Min Lee, Chang-Seok Ki, Duk L Na, Sang Won Seo, Hee Jin Ki. The Impact of APOE ɛ4 in Alzheimer's Disease Differs According to Age. Journal of Alzheimer's disease : JAD. vol 61. issue 4. 2019-01-24. PMID:29376853. |
the impact of apoe ɛ4 in alzheimer's disease differs according to age. |
2019-01-24 |
2023-08-13 |
Not clear |
| Vera Clemens, Francesca Regen, Nathalie Le Bret, Isabella Heuser, Julian Hellmann-Rege. Retinoic Acid Enhances Apolipoprotein E Synthesis in Human Macrophages. Journal of Alzheimer's disease : JAD. vol 61. issue 4. 2019-01-24. PMID:29376871. |
apolipoprotein e (apoe) represents a pivotal target in alzheimer's disease (ad) and is modulated through retinoic acid (ra), an endogenous neuroprotective and anti-inflammatory compound. |
2019-01-24 |
2023-08-13 |
human |
| Michael Peitz, Tamara Bechler, Catrin Cornelia Thiele, Monika Veltel, Melanie Bloschies, Klaus Fliessbach, Alfredo Ramirez, Oliver Brüstl. Blood-derived integration-free iPS cell line UKBi011-A from a diagnosed male Alzheimer's disease patient with APOE ɛ4/ɛ4 genotype. Stem cell research. vol 29. 2019-01-23. PMID:29753274. |
blood-derived integration-free ips cell line ukbi011-a from a diagnosed male alzheimer's disease patient with apoe ɛ4/ɛ4 genotype. |
2019-01-23 |
2023-08-13 |
human |
| Michael Peitz, Tamara Bechler, Catrin Cornelia Thiele, Monika Veltel, Melanie Bloschies, Klaus Fliessbach, Alfredo Ramirez, Oliver Brüstl. Blood-derived integration-free iPS cell line UKBi011-A from a diagnosed male Alzheimer's disease patient with APOE ɛ4/ɛ4 genotype. Stem cell research. vol 29. 2019-01-23. PMID:29753274. |
alzheimer's disease (ad) is most the frequent neurodegenerative disease, and the apoe ε4 allele is the most prominent risk factor for late-onset ad. |
2019-01-23 |
2023-08-13 |
human |
| Lisa M James, Stacy Dolan, Arthur C Leuthold, Brian E Engdahl, Angeliki Georgopoulos, Apostolos P Georgopoulo. The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women. EBioMedicine. vol 35. 2019-01-22. PMID:30139626. |
extensive research links apolipoprotein e (apoe) to brain function, with the e4 allele serving as a risk factor for brain disease, including alzheimer's disease, and the e2 allele conferring protection. |
2019-01-22 |
2023-08-13 |
human |
| Ta-Yuan Chang, Catherine Chan. ApoE and Lipid Homeostasis in Alzheimer's Disease: Introduction to the Thematic Review Series. Journal of lipid research. vol 58. issue 5. 2019-01-18. PMID:28258088. |
apoe and lipid homeostasis in alzheimer's disease: introduction to the thematic review series. |
2019-01-18 |
2023-08-13 |
Not clear |
| Simon Evans, Devin Clarke, Nicholas G Dowell, Naji Tabet, Sarah L King, Samuel B Hutton, Jennifer M Ruste. Using event-related fMRI to examine sustained attention processes and effects of APOE ε4 in young adults. PloS one. vol 13. issue 6. 2019-01-11. PMID:29856823. |
in this study we investigated effects of the apoe ε4 allele (which confers an enhanced risk of poorer cognitive ageing, and alzheimer's disease) on sustained attention (vigilance) performance in young adults using the rapid visual information processing (rvip) task and event-related fmri. |
2019-01-11 |
2023-08-13 |
human |
| Na Zhao, Chia-Chen Liu, Alexandra J Van Ingelgom, Cynthia Linares, Aishe Kurti, Joshua A Knight, Michael G Heckman, Nancy N Diehl, Mitsuru Shinohara, Yuka A Martens, Olivia N Attrebi, Leonard Petrucelli, John D Fryer, Zbigniew K Wszolek, Neill R Graff-Radford, Richard J Caselli, Monica Y Sanchez-Contreras, Rosa Rademakers, Melissa E Murray, Shunsuke Koga, Dennis W Dickson, Owen A Ross, Guojun B. APOE ε2 is associated with increased tau pathology in primary tauopathy. Nature communications. vol 9. issue 1. 2019-01-02. PMID:30348994. |
apolipoprotein e (apoe) ε4 allele is the strongest genetic risk factor for late-onset alzheimer's disease mainly by modulating amyloid-β pathology. |
2019-01-02 |
2023-08-13 |
mouse |
| Said El Shamieh, Christy Costanian, Rayan Kassir, Sophie Visvkis-Siest, Nisrine Bissar-Tadmour. APOE genotypes in Lebanon: distribution and association with hypercholesterolemia and Alzheimer's disease. Personalized medicine. vol 16. issue 1. 2019-01-02. PMID:30457419. |
apoe genotypes in lebanon: distribution and association with hypercholesterolemia and alzheimer's disease. |
2019-01-02 |
2023-08-13 |
Not clear |
| Said El Shamieh, Christy Costanian, Rayan Kassir, Sophie Visvkis-Siest, Nisrine Bissar-Tadmour. APOE genotypes in Lebanon: distribution and association with hypercholesterolemia and Alzheimer's disease. Personalized medicine. vol 16. issue 1. 2019-01-02. PMID:30457419. |
we first investigated the distribution of apoe genotypes in lebanese general population and alzheimer's disease study (ads) groups, and compared it with 1000 genomes populations. |
2019-01-02 |
2023-08-13 |
Not clear |
| Said El Shamieh, Christy Costanian, Rayan Kassir, Sophie Visvkis-Siest, Nisrine Bissar-Tadmour. APOE genotypes in Lebanon: distribution and association with hypercholesterolemia and Alzheimer's disease. Personalized medicine. vol 16. issue 1. 2019-01-02. PMID:30457419. |
then, we assessed eventual association between apoe genotypes, hypercholesterolemia and alzheimer's disease (ad). |
2019-01-02 |
2023-08-13 |
Not clear |
| Ling Li, Fan Zeng, Yu-Hui Liu, Hui-Yun Li, Shu-Yang Dong, Ze-Yan Peng, Yan-Jiang Wang, Hua-Dong Zho. CYP46A1 and the APOEε4 Allele Polymorphisms Correlate with the Risk of Alzheimer's Disease. Molecular neurobiology. vol 55. issue 10. 2018-12-18. PMID:29516283. |
polymorphisms of the cholesterol-24s-hydroxylase (cyp46a1) and apolipoprotein e (apoe) genes are risk factors for alzheimer's disease (ad). |
2018-12-18 |
2023-08-13 |
Not clear |
| Chao Ma, Jun Wang, Junying Zhang, Kewei Chen, Xin Li, Ni Shu, Yaojing Chen, Zhen Liu, Zhanjun Zhan. Disrupted Brain Structural Connectivity: Pathological Interactions Between Genetic APOE ε4 Status and Developed MCI Condition. Molecular neurobiology. vol 54. issue 9. 2018-12-17. PMID:27785756. |
the ε4 allele of the apolipoprotein e (apoe) gene and mild cognitive impairment (mci) are both risk factors for alzheimer's disease (ad). |
2018-12-17 |
2023-08-13 |
human |
| Alexander Drzezga, Daniele Altomare, Cristina Festari, Javier Arbizu, Stefania Orini, Karl Herholz, Peter Nestor, Federica Agosta, Femke Bouwman, Flavio Nobili, Zuzana Walker, Giovanni Battista Frisoni, Marina Boccard. Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer's disease. European journal of nuclear medicine and molecular imaging. vol 45. issue 9. 2018-12-12. PMID:29756163. |
to assess the clinical utility of 18f-fluorodeoxyglucose positron emission tomography (fdg-pet) for detection of early signs of neurodegeneration in conditions of increased risk for alzheimer's disease (ad) as defined by: subjective cognitive decline (scd), evidence of cerebral amyloid-pathology, apolipoprotein e (apoe) ε4-positive genotype, or autosomal dominant forms of ad (adad) in asymptomatic stages. |
2018-12-12 |
2023-08-13 |
human |
| Yeo Jin Kim, Sang Won Seo, Seong Beom Park, Jin Ju Yang, Jin San Lee, Juyoun Lee, Young Kyoung Jang, Sung Tae Kim, Kyung-Han Lee, Jong Min Lee, Jae-Hong Lee, Jae Seung Kim, Duk L Na, Hee Jin Ki. Protective effects of APOE e2 against disease progression in subcortical vascular mild cognitive impairment patients: A three-year longitudinal study. Scientific reports. vol 7. issue 1. 2018-12-11. PMID:28507298. |
although the association between apolipoprotein e (apoe) genotype and disease progression is well characterized in patients with alzheimer's disease, such a relationship is unknown in patients with subcortical vascular cognitive impairment. |
2018-12-11 |
2023-08-13 |
Not clear |
| Vincenzo De Luca, Gianfranco Spalletta, Renan P Souza, Ariel Graff, Luciana Bastos-Rodrigues, Maria Aparecida Camargos Bicalh. Definition of Late Onset Alzheimer's Disease and Anticipation Effect of Genome-Wide Significant Risk Variants: Pilot Study of the APOE e4 Allele. Neuropsychobiology. vol 77. issue 1. 2018-12-11. PMID:30110694. |
definition of late onset alzheimer's disease and anticipation effect of genome-wide significant risk variants: pilot study of the apoe e4 allele. |
2018-12-11 |
2023-08-13 |
Not clear |
| Vincenzo De Luca, Gianfranco Spalletta, Renan P Souza, Ariel Graff, Luciana Bastos-Rodrigues, Maria Aparecida Camargos Bicalh. Definition of Late Onset Alzheimer's Disease and Anticipation Effect of Genome-Wide Significant Risk Variants: Pilot Study of the APOE e4 Allele. Neuropsychobiology. vol 77. issue 1. 2018-12-11. PMID:30110694. |
this study aims to investigate the role of apolipoprotein e (apoe) e4 influencing the age at onset (aao) of alzheimer's disease (ad). |
2018-12-11 |
2023-08-13 |
Not clear |