| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michal Prendecki, Jolanta Florczak-Wyspianska, Marta Kowalska, Jan Ilkowski, Teresa Grzelak, Katarzyna Bialas, Wojciech Kozubski, Jolanta Dorszewsk. APOE genetic variants and apoE, miR-107 and miR-650 levels in Alzheimer's disease. Folia neuropathologica. vol 57. issue 2. 2020-02-20. PMID:31556571. |
apoe genetic variants and apoe, mir-107 and mir-650 levels in alzheimer's disease. |
2020-02-20 |
2023-08-13 |
Not clear |
| Keith Fluegg. Environmental factors influencing the link between APOE ε4 and Alzheimer's disease (AD) risk. International psychogeriatrics. vol 31. issue 2. 2020-02-19. PMID:29991368. |
environmental factors influencing the link between apoe ε4 and alzheimer's disease (ad) risk. |
2020-02-19 |
2023-08-13 |
human |
| Keith Fluegg. Environmental factors influencing the link between APOE ε4 and Alzheimer's disease (AD) risk. International psychogeriatrics. vol 31. issue 2. 2020-02-19. PMID:29991368. |
while apoe ε4 allele is considered a genetic risk factor for alzheimer's disease (ad), no relation existed between apoe ε4 and ad in the yoruba in nigeria among cohorts included in early prevalence waves. |
2020-02-19 |
2023-08-13 |
human |
| Xiaojing Li, Andrea Hildebrandt, Werner Sommer, Oliver Wilhelm, Martin Reuter, Christian Montag, Changsong Zho. Cognitive Performance in Young APOE ε4 Carriers: A Latent Variable Approach for Assessing the Genotype-Phenotype Relationship. Behavior genetics. vol 49. issue 5. 2020-02-14. PMID:31177340. |
the ε4 allele of the apolipoprotein (apoe) gene is a widely recognized genetic risk factor for developing alzheimer's disease in older age. |
2020-02-14 |
2023-08-13 |
human |
| Anil R Wadhwani, Amira Affaneh, Stephanie Van Gulden, John A Kessle. Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease. Annals of neurology. vol 85. issue 5. 2020-02-13. PMID:30840313. |
the apolipoprotein e (apoe) e4 isoform is the strongest genetic risk factor for sporadic alzheimer disease (ad). |
2020-02-13 |
2023-08-13 |
Not clear |
| Nicolette Mary Heinsinger, Mariam Alexandra Gachechiladze, G William Rebec. Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid. Journal of neuropathology and experimental neurology. vol 75. issue 10. 2020-02-05. PMID:27516118. |
apoe4 increases and apoe2 decreases the risk for alzheimer disease (ad) compared to the risk associated with apoe3 because apoe4 is less efficient at cholesterol efflux than apoe2 or apoe3 in vitro, we hypothesized that apoe genotype may affect apoe particle size in vivo and that these size differences may be related to ad risk. |
2020-02-05 |
2023-08-13 |
human |
| Zhuoran Li, Na Yang, Xiuxia Lei, Chuying Lin, Nan Li, Xinqing Jiang, Xinhua Wei, Banglao X. The association between the ApoE polymorphisms and the MRI-defined intracranial lesions in a cohort of southern China population. Journal of clinical laboratory analysis. vol 33. issue 7. 2020-02-05. PMID:31199015. |
the apolipoprotein e (apoe) ε4 allele is considered as a risk factor for alzheimer's disease (ad). |
2020-02-05 |
2023-08-13 |
Not clear |
| Dustin Chernick, Stephanie Ortiz-Valle, Angela Jeong, Wenhui Qu, Ling L. Peripheral versus central nervous system APOE in Alzheimer's disease: Interplay across the blood-brain barrier. Neuroscience letters. vol 708. 2020-02-03. PMID:31181302. |
peripheral versus central nervous system apoe in alzheimer's disease: interplay across the blood-brain barrier. |
2020-02-03 |
2023-08-13 |
Not clear |
| Dustin Chernick, Stephanie Ortiz-Valle, Angela Jeong, Wenhui Qu, Ling L. Peripheral versus central nervous system APOE in Alzheimer's disease: Interplay across the blood-brain barrier. Neuroscience letters. vol 708. 2020-02-03. PMID:31181302. |
the apolipoprotein e (apoe) ε4 allele has been demonstrated as the preeminent genetic risk factor for late onset alzheimer's disease (ad), which comprises greater than 90% of all ad cases. |
2020-02-03 |
2023-08-13 |
Not clear |
| Alexandra Grubman, Gabriel Chew, John F Ouyang, Guizhi Sun, Xin Yi Choo, Catriona McLean, Rebecca K Simmons, Sam Buckberry, Dulce B Vargas-Landin, Daniel Poppe, Jahnvi Pflueger, Ryan Lister, Owen J L Rackham, Enrico Petretto, Jose M Pol. A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation. Nature neuroscience. vol 22. issue 12. 2020-01-31. PMID:31768052. |
we report that the alzheimer's disease risk gene apoe is specifically repressed in alzheimer's disease oligodendrocyte progenitor cells and astrocyte subpopulations and upregulated in an alzheimer's disease-specific microglial subopulation. |
2020-01-31 |
2023-08-13 |
Not clear |
| Yu Yamazaki, Na Zhao, Thomas R Caulfield, Chia-Chen Liu, Guojun B. Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies. Nature reviews. Neurology. vol 15. issue 9. 2020-01-29. PMID:31367008. |
polymorphism in the apolipoprotein e (apoe) gene is a major genetic risk determinant of late-onset alzheimer disease (ad), with the apoe*ε4 allele conferring an increased risk and the apoe*ε2 allele conferring a decreased risk relative to the common apoe*ε3 allele. |
2020-01-29 |
2023-08-13 |
Not clear |
| Rosalinde E R Slot, Maartje I Kester, Argonde C Van Harten, Wesley Jongbloed, Femke H Bouwman, Charlotte E Teunissen, Philip Scheltens, Wiesje M van der Flier, Robert Veerhui. ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aβ42, levels in non-demented elderly. Neurobiology of aging. vol 79. 2020-01-27. PMID:31029938. |
we aimed to assess whether apoe affects early alzheimer's disease pathophysiology via these apolipoproteins. |
2020-01-27 |
2023-08-13 |
Not clear |
| Manish D Paranjpe, Xueqi Chen, Min Liu, Ishan Paranjpe, Jeffrey P Leal, Rongfu Wang, Martin G Pomper, Dean F Wong, Tammie L S Benzinger, Yun Zho. The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study. NeuroImage. Clinical. vol 22. 2020-01-21. PMID:30991617. |
while the apoe ε4 allele is a known risk factor for mild cognitive impairment (mci) and alzheimer's disease, brain region specific effects remain elusive. |
2020-01-21 |
2023-08-13 |
Not clear |
| Manish D Paranjpe, Xueqi Chen, Min Liu, Ishan Paranjpe, Jeffrey P Leal, Rongfu Wang, Martin G Pomper, Dean F Wong, Tammie L S Benzinger, Yun Zho. The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study. NeuroImage. Clinical. vol 22. 2020-01-21. PMID:30991617. |
in this study, we investigate whether the apoe ε4 allele exhibits brain region specific effects in longitudinal glucose uptake among patients with mci from the alzheimer's disease neuroimaging initiative (adni). |
2020-01-21 |
2023-08-13 |
Not clear |
| Joseph F Arboleda-Velasquez, Francisco Lopera, Michael O'Hare, Santiago Delgado-Tirado, Claudia Marino, Natalia Chmielewska, Kahira L Saez-Torres, Dhanesh Amarnani, Aaron P Schultz, Reisa A Sperling, David Leyton-Cifuentes, Kewei Chen, Ana Baena, David Aguillon, Silvia Rios-Romenets, Margarita Giraldo, Edmarie Guzmán-Vélez, Daniel J Norton, Enmanuelle Pardilla-Delgado, Arabiye Artola, Justin S Sanchez, Juliana Acosta-Uribe, Matthew Lalli, Kenneth S Kosik, Matthew J Huentelman, Henrik Zetterberg, Kaj Blennow, Rebecca A Reiman, Ji Luo, Yinghua Chen, Pradeep Thiyyagura, Yi Su, Gyungah R Jun, Marcus Naymik, Xiaowu Gai, Moiz Bootwalla, Jianling Ji, Lishuang Shen, John B Miller, Leo A Kim, Pierre N Tariot, Keith A Johnson, Eric M Reiman, Yakeel T Quiro. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nature medicine. vol 25. issue 11. 2020-01-20. PMID:31686034. |
our findings have implications for the role of apoe in the pathogenesis, treatment and prevention of alzheimer's disease. |
2020-01-20 |
2023-08-13 |
Not clear |
| Marya S Sabir, Cornelis Blauwendraat, Sarah Ahmed, Geidy E Serrano, Thomas G Beach, Matthew Perkins, Ann C Rice, Eliezer Masliah, Christopher M Morris, Lasse Pihlstrom, Alexander Pantelyat, Susan M Resnick, Mark R Cookson, Dena G Hernandez, Marilyn Albert, Ted M Dawson, Liana S Rosenthal, Henry Houlden, Olga Pletnikova, Juan Troncoso, Sonja W Schol. Assessment of APOE in atypical parkinsonism syndromes. Neurobiology of disease. vol 127. 2020-01-09. PMID:30798004. |
the apoe ε4 allele is a well-established risk factor for alzheimer's disease; however, the role of apoe in atypical parkinsonism syndromes remains controversial. |
2020-01-09 |
2023-08-13 |
Not clear |
| Marya S Sabir, Cornelis Blauwendraat, Sarah Ahmed, Geidy E Serrano, Thomas G Beach, Matthew Perkins, Ann C Rice, Eliezer Masliah, Christopher M Morris, Lasse Pihlstrom, Alexander Pantelyat, Susan M Resnick, Mark R Cookson, Dena G Hernandez, Marilyn Albert, Ted M Dawson, Liana S Rosenthal, Henry Houlden, Olga Pletnikova, Juan Troncoso, Sonja W Schol. Assessment of APOE in atypical parkinsonism syndromes. Neurobiology of disease. vol 127. 2020-01-09. PMID:30798004. |
we also performed genotyping and logistic regression analyses to examine apoe frequency and associated risk in patients with alzheimer's disease (n = 571) and parkinson's disease (n = 348). |
2020-01-09 |
2023-08-13 |
Not clear |
| Marya S Sabir, Cornelis Blauwendraat, Sarah Ahmed, Geidy E Serrano, Thomas G Beach, Matthew Perkins, Ann C Rice, Eliezer Masliah, Christopher M Morris, Lasse Pihlstrom, Alexander Pantelyat, Susan M Resnick, Mark R Cookson, Dena G Hernandez, Marilyn Albert, Ted M Dawson, Liana S Rosenthal, Henry Houlden, Olga Pletnikova, Juan Troncoso, Sonja W Schol. Assessment of APOE in atypical parkinsonism syndromes. Neurobiology of disease. vol 127. 2020-01-09. PMID:30798004. |
we demonstrate that apoe ε4 and ε2 carriers have a significantly increased and decreased risk, respectively, of developing alzheimer's disease (ε4: or: 4.13, 95% ci: 3.23-5.26, p = 3.67 × 10 |
2020-01-09 |
2023-08-13 |
Not clear |
| Qunxi Dong, Wen Zhang, Jianfeng Wu, Bolun Li, Emily H Schron, Travis McMahon, Jie Shi, Boris A Gutman, Kewei Chen, Leslie C Baxter, Paul M Thompson, Eric M Reiman, Richard J Caselli, Yalin Wan. Applying surface-based hippocampal morphometry to study APOE-E4 allele dose effects in cognitively unimpaired subjects. NeuroImage. Clinical. vol 22. 2019-12-26. PMID:30852398. |
apolipoprotein e (apoe) e4 is the major genetic risk factor for late-onset alzheimer's disease (ad). |
2019-12-26 |
2023-08-13 |
human |
| Ville Rantalainen, Jari Lahti, Eero Kajantie, Pentti Tienari, Johan G Eriksson, Katri Raikkone. APOE ɛ4, rs405509, and rs440446 promoter and intron-1 polymorphisms and dementia risk in a cohort of elderly Finns-Helsinki Birth Cohort Study. Neurobiology of aging. vol 73. 2019-12-19. PMID:30293724. |
we tested if the ε4 major isoform of the apoe gene and rs405509 and rs440446 promoter and intron-1 polymorphisms predicted risk of any dementia or alzheimer's disease with diagnoses derived from the hospital discharge and causes of death registers in 1453 participants of the helsinki birth cohort study. |
2019-12-19 |
2023-08-13 |
human |