| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Liu, Jing-Hui Song, Wei Xu, Xiao-He Hou, Jie-Qiong Li, Jin-Tai Yu, Lan Tan, Song Ch. The Associations of Cerebrospinal Fluid ApoE and Biomarkers of Alzheimer's Disease: Exploring Interactions With Sex. Frontiers in neuroscience. vol 15. 2021-03-23. PMID:33746700. |
the associations of cerebrospinal fluid apoe and biomarkers of alzheimer's disease: exploring interactions with sex. |
2021-03-23 |
2023-08-13 |
Not clear |
| Ying Liu, Jing-Hui Song, Wei Xu, Xiao-He Hou, Jie-Qiong Li, Jin-Tai Yu, Lan Tan, Song Ch. The Associations of Cerebrospinal Fluid ApoE and Biomarkers of Alzheimer's Disease: Exploring Interactions With Sex. Frontiers in neuroscience. vol 15. 2021-03-23. PMID:33746700. |
sex-related difference in alzheimer's disease (ad) has been proposed, and apolipoprotein e (apoe) isoforms have been suggested to be involved in the pathogenesis of ad. |
2021-03-23 |
2023-08-13 |
Not clear |
| Prag Batra, Kuan-Lin Huan. Genotype concordance and polygenic risk score estimation across consumer genetic testing data. Annals of human genetics. vol 84. issue 4. 2021-03-22. PMID:32436989. |
the discrepancy between the three sets of data resulted in different apoe genotypes and genetic risk scores of alzheimer's disease. |
2021-03-22 |
2023-08-13 |
Not clear |
| Tosha Williams, David R Borchelt, Paramita Chakrabart. Therapeutic approaches targeting Apolipoprotein E function in Alzheimer's disease. Molecular neurodegeneration. vol 15. issue 1. 2021-03-19. PMID:32005122. |
one of the primary genetic risk factors for alzheimer's disease (ad) is the presence of the Ɛ4 allele of apolipoprotein e (apoe). |
2021-03-19 |
2023-08-13 |
Not clear |
| Damián Hernández, Louise A Rooney, Maciej Daniszewski, Lerna Gulluyan, Helena H Liang, Anthony L Cook, Alex W Hewitt, Alice Péba. Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer's Disease. Stem cell reviews and reports. 2021-03-16. PMID:33725267. |
apolipoprotein e (apoe) is the most important susceptibility gene for late onset of alzheimer's disease (ad), with the presence of apoe-ε4 associated with increased risk of developing ad. |
2021-03-16 |
2023-08-13 |
human |
| Anna L Gharibyan, Tohidul Islam, Nina Pettersson, Solmaz A Golchin, Johanna Lundgren, Gabriella Johansson, Mélany Genot, Nina Schultz, Malin Wennström, Anders Olofsso. Apolipoprotein E Interferes with IAPP Aggregation and Protects Pericytes from IAPP-Induced Toxicity. Biomolecules. vol 10. issue 1. 2021-03-15. PMID:31947546. |
apolipoprotein e (apoe) has become a primary focus of research after the discovery of its strong linkage to alzheimer's disease (ad), where the apoe4 variant is the highest genetic risk factor for this disease. |
2021-03-15 |
2023-08-13 |
Not clear |
| Tongfei Liu, Bing Zhu, Yan Liu, Xiaoming Zhang, Jun Yin, Xiaoguang Li, LuLin Jiang, Andrew P Hodges, Sara Brin Rosenthal, Lisa Zhou, Joel Yancey, Amanda McQuade, Mathew Blurton-Jones, Rudolph E Tanzi, Timothy Y Huang, Huaxi X. Multi-omic comparison of Alzheimer's variants in human ESC-derived microglia reveals convergence at APOE. The Journal of experimental medicine. vol 217. issue 12. 2021-03-11. PMID:32941599. |
multi-omic comparison of alzheimer's variants in human esc-derived microglia reveals convergence at apoe. |
2021-03-11 |
2023-08-13 |
mouse |
| Anna O Giarratana, Cynthia Zheng, Sahithi Reddi, Shavonne L Teng, David Berger, Derek Adler, Patrick Sullivan, Smita Thakker-Varia, Janet Alde. APOE4 genetic polymorphism results in impaired recovery in a repeated mild traumatic brain injury model and treatment with Bryostatin-1 improves outcomes. Scientific reports. vol 10. issue 1. 2021-03-11. PMID:33199792. |
single nucleotide polymorphisms (snps) in apolipoprotein e (apoe) are known to increase risk for developing alzheimer's disease, however there is controversy from human and rodent studies as to whether apoe4 is a risk factor for worse outcomes after brain trauma. |
2021-03-11 |
2023-08-13 |
mouse |
| Jure Mur, Daniel L McCartney, Rosie M Walker, Archie Campbell, Mairead L Bermingham, Stewart W Morris, David J Porteous, Andrew M McIntosh, Ian J Deary, Kathryn L Evans, Riccardo E Marion. DNA methylation in APOE: The relationship with Alzheimer's and with cardiovascular health. Alzheimer's & dementia (New York, N. Y.). vol 6. issue 1. 2021-03-10. PMID:32346601. |
dna methylation in apoe: the relationship with alzheimer's and with cardiovascular health. |
2021-03-10 |
2023-08-13 |
Not clear |
| Mohammed Amir Husain, Benoit Laurent, Mélanie Plourd. APOE and Alzheimer's Disease: From Lipid Transport to Physiopathology and Therapeutics. Frontiers in neuroscience. vol 15. 2021-03-10. PMID:33679311. |
apoe and alzheimer's disease: from lipid transport to physiopathology and therapeutics. |
2021-03-10 |
2023-08-13 |
Not clear |
| Ching-On Won. Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes. International journal of molecular sciences. vol 21. issue 14. 2021-03-04. PMID:32708198. |
this review aims at summarizing the mounting evidence that has established the essential role of astrocytic endosomal-lysosomal organelles in the processing of amyloid precursor proteins, apolipoprotein e (apoe), tau, alpha synuclein, and huntingtin, which are associated with nds such as alzheimer's, parkinson's, and huntington diseases. |
2021-03-04 |
2023-08-13 |
Not clear |
| Steven Lehrer, Peter H Rheinstei. BIN1 rs744373 SNP and COVID-19 mortality. World Academy of Sciences journal. vol 3. issue 2. 2021-03-02. PMID:33521641. |
apolipoprotein e (apoe) e4 genotype, which increases the risk of alzheimer's disease (ad), predicted severe covid-19 infection in one uk biobank (ukb) cohort. |
2021-03-02 |
2023-08-13 |
Not clear |
| Vikram Venkatraghavan, Stefan Klein, Lana Fani, Leontine S Ham, Henri Vrooman, M Kamran Ikram, Wiro J Niessen, Esther E Bro. Analyzing the effect of APOE on Alzheimer's disease progression using an event-based model for stratified populations. NeuroImage. vol 227. 2021-03-01. PMID:33338617. |
analyzing the effect of apoe on alzheimer's disease progression using an event-based model for stratified populations. |
2021-03-01 |
2023-08-13 |
Not clear |
| Jodie B Nichols, Michael Malek-Ahmadi, Pierre N Tariot, Geidy E Serrano, Lucia I Sue, Thomas G Beac. Vascular Lesions, APOE ε4, and Tau Pathology in Alzheimer Disease. Journal of neuropathology and experimental neurology. vol 80. issue 3. 2021-02-26. PMID:33617650. |
vascular lesions, apoe ε4, and tau pathology in alzheimer disease. |
2021-02-26 |
2023-08-13 |
Not clear |
| Dianxu Ren, Oscar L Lopez, Jennifer H Lingler, Yvette Conle. The Effect of the APOE ε2ε4 Genotype on the Development of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) in Non-Latino Whites. Journal of the American Geriatrics Society. vol 68. issue 5. 2021-02-19. PMID:32017008. |
the effect of the apoe ε2ε4 genotype on the development of alzheimer's disease (ad) and mild cognitive impairment (mci) in non-latino whites. |
2021-02-19 |
2023-08-13 |
Not clear |
| Dianxu Ren, Oscar L Lopez, Jennifer H Lingler, Yvette Conle. The Effect of the APOE ε2ε4 Genotype on the Development of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) in Non-Latino Whites. Journal of the American Geriatrics Society. vol 68. issue 5. 2021-02-19. PMID:32017008. |
to examine the associations of apoe ε2ε4 with the development of alzheimer's disease (ad) and mild cognitive impairment (mci) in non-latino whites. |
2021-02-19 |
2023-08-13 |
Not clear |
| Sara G Aguilar-Navarro, Itzel I Gonzalez-Aparicio, José Alberto Avila-Funes, Teresa Juárez-Cedillo, Teresa Tusié-Luna, Alberto Jose Mimenza-Alvarad. Association between ApoE ε4 Carrier Status and Cardiovascular Risk Factors on Mild Cognitive Impairment among Mexican Older Adults. Brain sciences. vol 11. issue 1. 2021-02-18. PMID:33430178. |
cardiovascular risk factors (cvrf), such as hypertension, diabetes, or dyslipidemia, and the presence of the apolipoprotein e ε4 (apoe ε4) polymorphism have been associated with an increased risk of developing alzheimer's disease (ad) and other dementias but the relationship is inconsistent worldwide. |
2021-02-18 |
2023-08-13 |
Not clear |
| Yun Chen, Michael R Strickland, Andrea Soranno, David M Holtzma. Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis. Neuron. vol 109. issue 2. 2021-02-17. PMID:33176118. |
apolipoprotein e (apoe) is of great interest due to its role as a cholesterol/lipid transporter in the central nervous system (cns) and as the most influential genetic risk factor for alzheimer disease (ad). |
2021-02-17 |
2023-08-13 |
Not clear |
| Permal Deo, Varinderpal S Dhillon, Ann Chua, Philip Thomas, Michael Fenec. APOE ε4 Carriers Have a Greater Propensity to Glycation and sRAGE Which Is Further Influenced by RAGE G82S Polymorphism. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 75. issue 10. 2021-02-16. PMID:31677348. |
apoe ε4 allele is an established risk factor for alzheimer's disease and hypercholesterolemia. |
2021-02-16 |
2023-08-13 |
Not clear |
| David G Le Couteur, Fiona Stanaway, Louise M Waite, John Cullen, Richard I Lindley, Fiona M Blyth, Vasi Naganathan, Robert G Cumming, David J Handelsma. Apolipoprotein E and Health in Older Men: The Concord Health and Ageing in Men Project. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 75. issue 10. 2021-02-16. PMID:32342099. |
apoe genotype has been associated with various age-related outcomes including alzheimer's disease, frailty, and mortality. |
2021-02-16 |
2023-08-13 |
Not clear |