All Relations between Alzheimer Disease and apoe
| Publication | Sentence | Publish Date | Extraction Date | Species |
|---|---|---|---|---|
| Karolina Kauppi, Michael Rönnlund, Annelie Nordin Adolfsson, Sara Pudas, Rolf Adolfsso. Effects of polygenic risk for Alzheimer's disease on rate of cognitive decline in normal aging. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32709845. | although apoe ɛ4 and genetic scores for late-onset alzheimer's disease (load) have been related to cognitive decline during preclinical stages of dementia, there is limited knowledge concerning genetic factors implied in normal cognitive aging. | 2021-06-18 | 2023-08-13 | human |
| Chia-Liang Tsai, Kirk I Erickson, H-Sunny Sun, Yu-Min Kuo, Ming-Chyi Pa. A cross-sectional examination of a family history of Alzheimer's disease and ApoE epsilon 4 on physical fitness, molecular biomarkers, and neurocognitive performance. Physiology & behavior. vol 230. 2021-06-18. PMID:33383402. | a cross-sectional examination of a family history of alzheimer's disease and apoe epsilon 4 on physical fitness, molecular biomarkers, and neurocognitive performance. | 2021-06-18 | 2023-08-13 | Not clear |
| Chia-Liang Tsai, Kirk I Erickson, H-Sunny Sun, Yu-Min Kuo, Ming-Chyi Pa. A cross-sectional examination of a family history of Alzheimer's disease and ApoE epsilon 4 on physical fitness, molecular biomarkers, and neurocognitive performance. Physiology & behavior. vol 230. 2021-06-18. PMID:33383402. | the present study examined whether the ɛ4 allele of the apolipoprotein e (apoe) gene impacts molecular biomarkers and neurocognitive performance among individuals at genetic risk for developing alzheimer's disease (ad). | 2021-06-18 | 2023-08-13 | Not clear |
| Zheng Zhu, Yang Yang, Zhenxu Xiao, Qianhua Zhao, Wanqing Wu, Xiaoniu Liang, Jianfeng Luo, Yang Cao, Minhua Shao, Qihao Guo, Ding Din. TOMM40 and APOE variants synergistically increase the risk of Alzheimer's disease in a Chinese population. Aging clinical and experimental research. vol 33. issue 6. 2021-06-16. PMID:32725468. | tomm40 and apoe variants synergistically increase the risk of alzheimer's disease in a chinese population. | 2021-06-16 | 2023-08-13 | Not clear |
| Zheng Zhu, Yang Yang, Zhenxu Xiao, Qianhua Zhao, Wanqing Wu, Xiaoniu Liang, Jianfeng Luo, Yang Cao, Minhua Shao, Qihao Guo, Ding Din. TOMM40 and APOE variants synergistically increase the risk of Alzheimer's disease in a Chinese population. Aging clinical and experimental research. vol 33. issue 6. 2021-06-16. PMID:32725468. | the apolipoprotein e (apoe) ε4 allele is a strong risk factor for alzheimer's disease (ad) in caucasian and african american populations. | 2021-06-16 | 2023-08-13 | Not clear |
| Itziar de Rojas, Sonia Moreno-Grau, Niccolo Tesi, Benjamin Grenier-Boley, Victor Andrade, Iris E Jansen, Nancy L Pedersen, Najada Stringa, Anna Zettergren, Isabel Hernández, Laura Montrreal, Carmen Antúnez, Anna Antonell, Rick M Tankard, Joshua C Bis, Rebecca Sims, Céline Bellenguez, Inés Quintela, Antonio González-Perez, Miguel Calero, Emilio Franco-Macías, Juan Macías, Rafael Blesa, Laura Cervera-Carles, Manuel Menéndez-González, Ana Frank-García, Jose Luís Royo, Fermin Moreno, Raquel Huerto Vilas, Miquel Baquero, Mónica Diez-Fairen, Carmen Lage, Sebastián García-Madrona, Pablo García-González, Emilio Alarcón-Martín, Sergi Valero, Oscar Sotolongo-Grau, Abbe Ullgren, Adam C Naj, Afina W Lemstra, Alba Benaque, Alba Pérez-Cordón, Alberto Benussi, Alberto Rábano, Alessandro Padovani, Alessio Squassina, Alexandre de Mendonça, Alfonso Arias Pastor, Almar A L Kok, Alun Meggy, Ana Belén Pastor, Ana Espinosa, Anaïs Corma-Gómez, Angel Martín Montes, Ángela Sanabria, Anita L DeStefano, Anja Schneider, Annakaisa Haapasalo, Anne Kinhult Ståhlbom, Anne Tybjærg-Hansen, Annette M Hartmann, Annika Spottke, Arturo Corbatón-Anchuelo, Arvid Rongve, Barbara Borroni, Beatrice Arosio, Benedetta Nacmias, Børge G Nordestgaard, Brian W Kunkle, Camille Charbonnier, Carla Abdelnour, Carlo Masullo, Carmen Martínez Rodríguez, Carmen Muñoz-Fernandez, Carole Dufouil, Caroline Graff, Catarina B Ferreira, Caterina Chillotti, Chandra A Reynolds, Chiara Fenoglio, Christine Van Broeckhoven, Christopher Clark, Claudia Pisanu, Claudia L Satizabal, Clive Holmes, Dolores Buiza-Rueda, Dag Aarsland, Dan Rujescu, Daniel Alcolea, Daniela Galimberti, David Wallon, Davide Seripa, Edna Grünblatt, Efthimios Dardiotis, Emrah Düzel, Elio Scarpini, Elisa Conti, Elisa Rubino, Ellen Gelpi, Eloy Rodriguez-Rodriguez, Emmanuelle Duron, Eric Boerwinkle, Evelyn Ferri, Fabrizio Tagliavini, Fahri Küçükali, Florence Pasquier, Florentino Sanchez-Garcia, Francesca Mangialasche, Frank Jessen, Gaël Nicolas, Geir Selbæk, Gemma Ortega, Geneviève Chêne, Georgios Hadjigeorgiou, Giacomina Rossi, Gianfranco Spalletta, Giorgio Giaccone, Giulia Grande, Giuliano Binetti, Goran Papenberg, Harald Hampel, Henri Bailly, Henrik Zetterberg, Hilkka Soininen, Ida K Karlsson, Ignacio Alvarez, Ildebrando Appollonio, Ina Giegling, Ingmar Skoog, Ingvild Saltvedt, Innocenzo Rainero, Irene Rosas Allende, Jakub Hort, Janine Diehl-Schmid, Jasper Van Dongen, Jean-Sebastien Vidal, Jenni Lehtisalo, Jens Wiltfang, Jesper Qvist Thomassen, Johannes Kornhuber, Jonathan L Haines, Jonathan Vogelgsang, Juan A Pineda, Juan Fortea, Julius Popp, Jürgen Deckert, Katharina Buerger, Kevin Morgan, Klaus Fließbach, Kristel Sleegers, Laura Molina-Porcel, Lena Kilander, Leonie Weinhold, Lindsay A Farrer, Li-San Wang, Luca Kleineidam, Lucia Farotti, Lucilla Parnetti, Lucio Tremolizzo, Lucrezia Hausner, Luisa Benussi, Lutz Froelich, M Arfan Ikram, M Candida Deniz-Naranjo, Magda Tsolaki, Maitée Rosende-Roca, Malin Löwenmark, Marc Hulsman, Marco Spallazzi, Margaret A Pericak-Vance, Margaret Esiri, María Bernal Sánchez-Arjona, Maria Carolina Dalmasso, María Teresa Martínez-Larrad, Marina Arcaro, Markus M Nöthen, Marta Fernández-Fuertes, Martin Dichgans, Martin Ingelsson, Martin J Herrmann, Martin Scherer, Martin Vyhnalek, Mary H Kosmidis, Mary Yannakoulia, Matthias Schmid, Michael Ewers, Michael T Heneka, Michael Wagner, Michela Scamosci, Miia Kivipelto, Mikko Hiltunen, Miren Zulaica, Montserrat Alegret, Myriam Fornage, Natalia Roberto, Natasja M van Schoor, Nazib M Seidu, Nerisa Banaj, Nicola J Armstrong, Nikolaos Scarmeas, Norbert Scherbaum, Oliver Goldhardt, Oliver Hanon, Oliver Peters, Olivia Anna Skrobot, Olivier Quenez, Ondrej Lerch, Paola Bossù, Paolo Caffarra, Paolo Dionigi Rossi, Paraskevi Sakka, Per Hoffmann, Peter A Holmans, Peter Fischer, Peter Riederer, Qiong Yang, Rachel Marshall, Rajesh N Kalaria, Richard Mayeux, Rik Vandenberghe, Roberta Cecchetti, Roberta Ghidoni, Ruth Frikke-Schmidt, Sandro Sorbi, Sara Hägg, Sebastiaan Engelborghs, Seppo Helisalmi, Sigrid Botne Sando, Silke Kern, Silvana Archetti, Silvia Boschi, Silvia Fostinelli, Silvia Gil, Silvia Mendoza, Simon Mead, Simona Ciccone, Srdjan Djurovic, Stefanie Heilmann-Heimbach, Steffi Riedel-Heller, Teemu Kuulasmaa, Teodoro Del Ser, Thibaud Lebouvier, Thomas Polak, Tiia Ngandu, Timo Grimmer, Valentina Bessi, Valentina Escott-Price, Vilmantas Giedraitis, Vincent Deramecourt, Wolfgang Maier, Xueqiu Jian, Yolande A L Pijnenburg, Patrick Gavin Kehoe, Guillermo Garcia-Ribas, Pascual Sánchez-Juan, Pau Pastor, Jordi Pérez-Tur, Gerard Piñol-Ripoll, Adolfo Lopez de Munain, Jose María García-Alberca, María J Bullido, Victoria Álvarez, Alberto Lleó, Luis M Real, Pablo Mir, Miguel Medina, Philip Scheltens, Henne Holstege, Marta Marquié, María Eugenia Sáez, Ángel Carracedo, Philippe Amouyel, Gerard D Schellenberg, Julie Williams, Sudha Seshadri, Cornelia M van Duijn, Karen A Mather, Raquel Sánchez-Valle, Manuel Serrano-Ríos, Adelina Orellana, Lluís Tárraga, Kaj Blennow, Martijn Huisman, Ole A Andreassen, Danielle Posthuma, Jordi Clarimón, Mercè Boada, Wiesje M van der Flier, Alfredo Ramirez, Jean-Charles Lambert, Sven J van der Lee, Agustín Rui. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature communications. vol 12. issue 1. 2021-06-15. PMID:34099642. | assessment of the polygenic risk score and stratifying by apoe reveal a 4 to 5.5 years difference in median age at onset of alzheimer's disease patients in apoe ɛ4 carriers. | 2021-06-15 | 2023-08-13 | Not clear |
| Nicholas F Fitz, Kyong Nyon Nam, Cody M Wolfe, Florent Letronne, Brittany E Playso, Bistra E Iordanova, Takashi D Y Kozai, Richard J Biedrzycki, Valerian E Kagan, Yulia Y Tyurina, Xianlin Han, Iliya Lefterov, Radosveta Koldamov. Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease. Nature communications. vol 12. issue 1. 2021-06-15. PMID:34099706. | phospholipids of apoe lipoproteins activate microglia in an isoform-specific manner in preclinical models of alzheimer's disease. | 2021-06-15 | 2023-08-13 | mouse |
| Nicholas F Fitz, Kyong Nyon Nam, Cody M Wolfe, Florent Letronne, Brittany E Playso, Bistra E Iordanova, Takashi D Y Kozai, Richard J Biedrzycki, Valerian E Kagan, Yulia Y Tyurina, Xianlin Han, Iliya Lefterov, Radosveta Koldamov. Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease. Nature communications. vol 12. issue 1. 2021-06-15. PMID:34099706. | apoe and trem2 are major genetic risk factors for alzheimer's disease (ad), but how they affect microglia response to aβ remains unclear. | 2021-06-15 | 2023-08-13 | mouse |
| Parichita Choudhury, Vijay K Ramanan, Bradley F Boev. APOE Allele Testing and Alzheimer Disease-Reply. JAMA. vol 325. issue 21. 2021-06-14. PMID:34061147. | apoe allele testing and alzheimer disease-reply. | 2021-06-14 | 2023-08-13 | Not clear |
| Mu-Hong Chen, Fu-Chi Yang, Chih-Sung Lian. APOE Allele Testing and Alzheimer Disease. JAMA. vol 325. issue 21. 2021-06-14. PMID:34061149. | apoe allele testing and alzheimer disease. | 2021-06-14 | 2023-08-13 | Not clear |
| b' Juraj Javor, Vladim\\xc3\\xadra \\xc4\\x8eurmanov\\xc3\\xa1, Zuzana P\\xc3\\xa1rnick\\xc3\\xa1, Gabriel Min\\xc3\\xa1rik, M\\xc3\\xa1ria Kr\\xc3\\xa1lov\\xc3\\xa1, J\\xc3\\xa1n Pe\\xc4\\x8de\\xc5\\x88\\xc3\\xa1k, Barbora Va\\xc5\\xa1e\\xc4\\x8dkov\\xc3\\xa1, Veronika Re\\xc5\\xben\\xc3\\xa1kov\\xc3\\xa1, Stanislav \\xc5\\xa0utovsk\\xc3\\xbd, Karin Gmitterov\\xc3\\xa1, Tom\\xc3\\xa1\\xc5\\xa1 Hrom\\xc3\\xa1dka, \\xc4\\xbdubica Peterajov\\xc3\\xa1, Ivana Shawkatov\\xc3\\xa. Association of CD33 rs3865444:C\\xcb\\x83A polymorphism with a reduced risk of late-onset Alzheimer\'s disease in Slovaks is limited to subjects carrying the APOE \\xce\\xb54 allele. International journal of immunogenetics. vol 47. issue 5. 2021-06-09. PMID:32333488.' | association of cd33 rs3865444:c˃a polymorphism with a reduced risk of late-onset alzheimer's disease in slovaks is limited to subjects carrying the apoe ε4 allele. | 2021-06-09 | 2023-08-13 | human |
| Lu Zhao, Ishaan Batta, William Matloff, Caroline O'Driscoll, Samuel Hobel, Arthur W Tog. Neuroimaging PheWAS (Phenome-Wide Association Study): A Free Cloud-Computing Platform for Big-Data, Brain-Wide Imaging Association Studies. Neuroinformatics. vol 19. issue 2. 2021-06-08. PMID:32822005. | we demonstrated the potential of neuroimaging phewas with a case study analyzing the influences of the apolipoprotein e (apoe) gene on various brain morphological properties across the brain in the alzheimer's disease neuroimaging initiative (adni) cohort. | 2021-06-08 | 2023-08-13 | Not clear |
| Gabrielle Pfutzenreuter, Kenny Nieradka, Márcia Regina Pincerati, Ilton Santos da Silv. Intracerebroventricular streptozotocin induces behavioral impairments and increases short‑term C3 gene expression in the hippocampus of Wistar rats. Acta neurobiologiae experimentalis. vol 80. issue 2. 2021-06-07. PMID:32602856. | the behavioral tests were followed by brain removal and hippocampal dissection for rna extraction and qrt‑pcr to assess the expression levels of 4 alzheimer's disease related genes: mapt, apoe, c3 and ps‑1. | 2021-06-07 | 2023-08-13 | rat |
| Aladdin Riad, Zsofia Lengyel-Zhand, Chenbo Zeng, Chi-Chang Weng, Virginia M-Y Lee, John Q Trojanowski, Robert H Mac. The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates. Molecular neurobiology. vol 57. issue 9. 2021-06-03. PMID:32572762. | these receptors are expressed in the nervous system where they have implications in neurodegenerative diseases such as alzheimer's disease (ad), where apoe is involved in neuronal uptake and accumulation of aβ42, eventually cascading into neurodegeneration, synaptic dysfunction, and ultimately, dementia. | 2021-06-03 | 2023-08-13 | Not clear |
| Amy C Ferguson, Rachana Tank, Laura M Lyall, Joey Ward, Carlos Celis-Morales, Rona Strawbridge, Frederick Ho, Christopher D Whelan, Jason Gill, Paul Welsh, Jana J Anderson, Patrick B Mark, Daniel F Mackay, Daniel J Smith, Jill P Pell, Jonathan Cavanagh, Naveed Sattar, Donald M Lyal. Alzheimer's Disease Susceptibility Gene Apolipoprotein E (APOE) and Blood Biomarkers in UK Biobank (N = 395,769). Journal of Alzheimer's disease : JAD. vol 76. issue 4. 2021-06-03. PMID:32651323. | alzheimer's disease susceptibility gene apolipoprotein e (apoe) and blood biomarkers in uk biobank (n = 395,769). | 2021-06-03 | 2023-08-13 | Not clear |
| Jaclyn Iannucci, Abhik Sen, Paula Gramma. Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro. Current issues in molecular biology. vol 43. issue 1. 2021-06-03. PMID:34071762. | mutations to the cholesterol transport protein apolipoprotein e (apoe) have been identified as a major risk factor for the development of sporadic or late-onset alzheimer's disease (ad), with the | 2021-06-03 | 2023-08-13 | Not clear |
| Shaozhen Yan, Chaojie Zheng, Manish D Paranjpe, Jian Li, Tammie L S Benzinger, Jie Lu, Yun Zho. Association of sex and APOE ε4 with brain tau deposition and atrophy in older adults with Alzheimer's disease. Theranostics. vol 10. issue 23. 2021-06-01. PMID:32929366. | association of sex and apoe ε4 with brain tau deposition and atrophy in older adults with alzheimer's disease. | 2021-06-01 | 2023-08-13 | Not clear |
| Shaozhen Yan, Chaojie Zheng, Manish D Paranjpe, Jian Li, Tammie L S Benzinger, Jie Lu, Yun Zho. Association of sex and APOE ε4 with brain tau deposition and atrophy in older adults with Alzheimer's disease. Theranostics. vol 10. issue 23. 2021-06-01. PMID:32929366. | the objective of this study was to assess the association of sex and the apolipoprotein e (apoe) ε4 allele with brain tau deposition and atrophy in older adults with alzheimer's disease (ad) using quantitative | 2021-06-01 | 2023-08-13 | Not clear |
| Xia Chen, Guo-Ying Dong, Lin-Xiao Wan. High-frequency transcranial magnetic stimulation protects APP/PS1 mice against Alzheimer's disease progress by reducing APOE and enhancing autophagy. Brain and behavior. vol 10. issue 8. 2021-05-31. PMID:32592331. | high-frequency transcranial magnetic stimulation protects app/ps1 mice against alzheimer's disease progress by reducing apoe and enhancing autophagy. | 2021-05-31 | 2023-08-13 | mouse |
| Aivi T Nguyen, Kui Wang, Gang Hu, Xuran Wang, Zhen Miao, Joshua A Azevedo, EunRan Suh, Vivianna M Van Deerlin, David Choi, Kathryn Roeder, Mingyao Li, Edward B Le. APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease. Acta neuropathologica. vol 140. issue 4. 2021-05-31. PMID:32840654. | apoe and trem2 regulate amyloid-responsive microglia in alzheimer's disease. | 2021-05-31 | 2023-08-13 | human |