| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W A Kukull, G D Schellenberg, J D Bowen, W C McCormick, C E Yu, L Teri, J D Thompson, E S O'Meara, E B Larso. Apolipoprotein E in Alzheimer's disease risk and case detection: a case-control study. Journal of clinical epidemiology. vol 49. issue 10. 1996-10-29. PMID:8826994. |
the objective of this study was to describe the association between the epsilon 4 allele of the apolipoprotein e gene (apoe e4) and alzheimer's disease (ad) and to evaluate apoe e4 genotyping as a test for ad. |
1996-10-29 |
2023-08-12 |
human |
| H Soininen, M Lehtovirta, S Helisalmi, K Linnaranta, O Heinonen, P Riekkine. Increased acetylcholinesterase activity in the CSF of Alzheimer patients carrying apolipoprotein epsilon4 allele. Neuroreport. vol 6. issue 18. 1996-10-24. PMID:8741753. |
we measured csf acetylcholinesterase (ache) activity in 57 alzheimer's disease (ad) patients with different apolipoprotein e (apoe) genotypes at the early stage of the disease, and in 11 non-demented controls. |
1996-10-24 |
2023-08-12 |
Not clear |
| M Miyata, J D Smit. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nature genetics. vol 14. issue 1. 1996-10-24. PMID:8782820. |
the apolipoprotein e (apoe) e4 allele is associated with alzheimer's disease, cardiovascular disease, and decreased longevity. |
1996-10-24 |
2023-08-12 |
Not clear |
| M Ishiguro, Y Imai, S Kohsak. Expression and distribution of low density lipoprotein receptor-related protein mRNA in the rat central nervous system. Brain research. Molecular brain research. vol 33. issue 1. 1996-10-23. PMID:8774944. |
recently it has been reported that apoe4, one of three common isoforms of apoe, is a main risk factor of alzheimer's disease (ad). |
1996-10-23 |
2023-08-12 |
rat |
| P Bertrand, J Poirier, T Oda, C E Finch, G M Pasinett. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Brain research. Molecular brain research. vol 33. issue 1. 1996-10-23. PMID:8774959. |
this study examines the relationship between the levels of apolipoprotein e (apoe) and apolipoprotein j (apoj, also designated as clusterin) as a function of apoe genotype in the hippocampus and cortex of alzheimer disease (ad) subjects. |
1996-10-23 |
2023-08-12 |
human |
| A Nunomura, S Chiba, M Eto, M Saito, I Makino, T Miyagish. Apolipoprotein E polymorphism and susceptibility to early- and late-onset sporadic Alzheimer's disease in Hokkaido, the northern part of Japan. Neuroscience letters. vol 206. issue 1. 1996-10-21. PMID:8848271. |
apolipoprotein e (apoe) phenotypes and corresponding allele frequencies were examined in 72 patients (50-90 years of age) with sporadic alzheimer's disease (ad) and 83 elderly controls (61-96 years of age) in hokkaido, the northern part of japan. |
1996-10-21 |
2023-08-12 |
Not clear |
| K Isoe, K Urakami, K Sato, K Takahash. Apolipoprotein E in patients with dementia of the Alzheimer type and vascular dementia. Acta neurologica Scandinavica. vol 93. issue 2-3. 1996-10-18. PMID:8741132. |
the phenotypes of apolipoprotein e (apoe) in the plasma of patients with dementia of the alzheimer type (dat) and vascular dementia (vd) were determined by the isoelectric focusing method. |
1996-10-18 |
2023-08-12 |
human |
| J Norrman, A J Brookes, C Yates, D St Clai. Apolipoprotein E genotype and its effect on duration and severity of early and late onset Alzheimer's disease. The British journal of psychiatry : the journal of mental science. vol 167. issue 4. 1996-10-16. PMID:8829725. |
the apolipoprotein e (apoe) epsilon 4 allele is associated with an increased risk of senile and probably presenile alzheimer's disease. |
1996-10-16 |
2023-08-12 |
Not clear |
| S E Poduslo, M Neal, J Schwankhau. A closely linked gene to apolipoprotein E may serve as an additional risk factor for Alzheimer's disease. Neuroscience letters. vol 201. issue 1. 1996-10-16. PMID:8830319. |
the e4 allele of the apolipoprotein e (apoe) gene has been identified as a risk factor for alzheimer's disease. |
1996-10-16 |
2023-08-12 |
Not clear |
| N Rösler, I Wichart, K A Jellinge. Intra vitam lumbar cerebrospinal fluid and serum and postmortem ventricular immunoreactive apolipoprotein E in patients with Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry. vol 60. issue 4. 1996-09-27. PMID:8774418. |
on the other hand, apoe determinations could be useful as part of a neurochemical profile of alzheimer's disease. |
1996-09-27 |
2023-08-12 |
Not clear |
| R Scacchi, L De Bernardini, E Mantuano, L M Donini, T Vilardo, R M Corb. Apolipoprotein E (APOE) allele frequencies in late-onset sporadic Alzheimer's disease (AD), mixed dementia and vascular dementia: lack of association of epsilon 4 allele with AD in Italian octogenarian patients. Neuroscience letters. vol 201. issue 3. 1996-09-26. PMID:8786847. |
apolipoprotein e (apoe) allele frequencies in late-onset sporadic alzheimer's disease (ad), mixed dementia and vascular dementia: lack of association of epsilon 4 allele with ad in italian octogenarian patients. |
1996-09-26 |
2023-08-12 |
human |
| R Scacchi, L De Bernardini, E Mantuano, L M Donini, T Vilardo, R M Corb. Apolipoprotein E (APOE) allele frequencies in late-onset sporadic Alzheimer's disease (AD), mixed dementia and vascular dementia: lack of association of epsilon 4 allele with AD in Italian octogenarian patients. Neuroscience letters. vol 201. issue 3. 1996-09-26. PMID:8786847. |
the apolipoprotein e (apoe) epsilon 4 allele has been found to be strongly associated with alzheimer's disease (ad) in most studies conducted up to now, though not all investigators have established a similar association with other forms of dementia, like vascular dementia. |
1996-09-26 |
2023-08-12 |
human |
| V S Rao, A Cupples, C M van Duijn, A Kurz, R C Green, H Chui, R Duara, S A Auerbach, L Volicer, J Wells, C van Broeckhoven, J H Growdon, J L Haines, L A Farre. Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4. American journal of human genetics. vol 59. issue 3. 1996-09-25. PMID:8751868. |
apolipoprotein e (apoe) genotype is the single most important determinant to the common form of alzheimer disease (ad) yet identified. |
1996-09-25 |
2023-08-12 |
Not clear |
| V S Rao, A Cupples, C M van Duijn, A Kurz, R C Green, H Chui, R Duara, S A Auerbach, L Volicer, J Wells, C van Broeckhoven, J H Growdon, J L Haines, L A Farre. Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4. American journal of human genetics. vol 59. issue 3. 1996-09-25. PMID:8751868. |
we carried out a complex segregation analysis in 636 nuclear families of consecutively ascertained and rigorously diagnosed probands in the multi-institutional research in alzheimer genetic epidemiology study in order to derive models of disease transmission which account for the influences of apoe genotype of the proband and gender. |
1996-09-25 |
2023-08-12 |
Not clear |
| T J Montine, D Y Huang, W M Valentine, V Amarnath, A Saunders, K H Weisgraber, D G Graham, W J Strittmatte. Crosslinking of apolipoprotein E by products of lipid peroxidation. Journal of neuropathology and experimental neurology. vol 55. issue 2. 1996-09-20. PMID:8786379. |
apolipoprotein e (apoe) genotype and advancing aging are interacting ri sk factors in the expression of late onset and sporadic alzheimer's disease (ad). |
1996-09-20 |
2023-08-12 |
human |
| R E Metzger, M J LaDu, J B Pan, G S Getz, D E Frail, M T Faldut. Neurons of the human frontal cortex display apolipoprotein E immunoreactivity: implications for Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 55. issue 3. 1996-09-20. PMID:8786396. |
genetic evidence demonstrates an overrepresentation of the apoe epsilon 4 allele in alzheimer's disease (ad). |
1996-09-20 |
2023-08-12 |
human |
| R H Christie, H Chung, G W Rebeck, D Strickland, B T Hyma. Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 55. issue 4. 1996-09-20. PMID:8786409. |
further characterizations of apoe receptors in alzheimer brain may help lay the groundwork for understanding the role of apoe in the cns and in the pathophysiology of ad. |
1996-09-20 |
2023-08-12 |
Not clear |
| J M Olichney, L A Hansen, D Galasko, T Saitoh, C R Hofstetter, R Katzman, L J Tha. The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant. Neurology. vol 47. issue 1. 1996-09-12. PMID:8710076. |
to determine the relationship between apolipoprotein e (apoe) genotype and neuropathologic lesions in alzheimer's disease (ad) and lewy body variant (lbv). |
1996-09-12 |
2023-08-12 |
Not clear |
| I Gordon, S Ben-Eliyahu, E Rosenne, E Sehayek, D M Michaelso. Derangement in stress response of apolipoprotein E-deficient mice. Neuroscience letters. vol 206. issue 2-3. 1996-09-12. PMID:8710189. |
apolipoprotein e (apoe) is associated with familial and sporadic alzheimer's disease (ad). |
1996-09-12 |
2023-08-12 |
mouse |
| A J Slooter, M B Breteler, A Ott, C Van Broeckhoven, C M van Duij. APOE genotyping in differential diagnosis of Alzheimer's disease. Lancet (London, England). vol 348. issue 9023. 1996-09-06. PMID:8709703. |
apoe genotyping in differential diagnosis of alzheimer's disease. |
1996-09-06 |
2023-08-12 |
Not clear |