| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M I Kamboh, D K Sanghera, C E Aston, C H Bunker, R F Hamman, R E Ferrell, S T DeKosk. Gender-specific nonrandom association between the alpha 1-antichymotrypsin and apolipoprotein E polymorphisms in the general population and its implication for the risk of Alzheimer's disease. Genetic epidemiology. vol 14. issue 2. 1997-07-16. PMID:9129962. |
these data indicate the existence of a nonrandom association between the apoe and act loci in women which may have an important implication for the higher prevalence of alzheimer's disease in women. |
1997-07-16 |
2023-08-12 |
Not clear |
| J A Nicoll, C Burnett, S Love, D I Graham, D Dewar, J W Ironside, J Stewart, H V Vinter. High frequency of apolipoprotein E epsilon 2 allele in hemorrhage due to cerebral amyloid angiopathy. Annals of neurology. vol 41. issue 6. 1997-07-10. PMID:9189032. |
from the somewhat conflicting published data on apolipoprotein e (apoe) genotype in hemorrhage due to cerebral amyloid angiopathy (caa), it is unclear whether apoe genotype influences the risk of caa-related hemorrhage independently of its association with concomitant alzheimer's disease (ad). |
1997-07-10 |
2023-08-12 |
Not clear |
| A Schlenck, K Bohnet, D Aguillon, C Lafaurie, G Siest, S Visviki. High sensitivity of laser-induced fluorescence detection in capillary gel electrophoresis for accurate apolipoprotein E genotyping. BioTechniques. vol 22. issue 4. 1997-07-08. PMID:9105626. |
accurate apoe phenotyping or genotyping has become essential in clinical laboratories, since the epsilon 4 allele has been associated with cardiovascular and alzheimer's diseases. |
1997-07-08 |
2023-08-12 |
human |
| G A Higgins, C H Large, H T Rupniak, J C Barne. Apolipoprotein E and Alzheimer's disease: a review of recent studies. Pharmacology, biochemistry, and behavior. vol 56. issue 4. 1997-07-07. PMID:9130294. |
in 1993, the apoe genotype was identified as a risk factor for alzheimer's disease (ad) and was subsequently acknowledged to account for approximately 60% of all cases. |
1997-07-07 |
2023-08-12 |
Not clear |
| F Richard, N Helbecque, E Neuman, D Guez, R Levy, P Amouye. APOE genotyping and response to drug treatment in Alzheimer's disease. Lancet (London, England). vol 349. issue 9051. 1997-06-26. PMID:9048794. |
apoe genotyping and response to drug treatment in alzheimer's disease. |
1997-06-26 |
2023-08-12 |
Not clear |
| D Fallin, S Reading, J Schinka, J Hoyne, P Scibelli, M Gold, F Crawford, M Mulla. No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease. American journal of medical genetics. vol 74. issue 2. 1997-06-18. PMID:9129722. |
no interaction between the apoe and the alpha-1-antichymotrypsin genes on risk for alzheimer's disease. |
1997-06-18 |
2023-08-12 |
Not clear |
| D Fallin, S Reading, J Schinka, J Hoyne, P Scibelli, M Gold, F Crawford, M Mulla. No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease. American journal of medical genetics. vol 74. issue 2. 1997-06-18. PMID:9129722. |
by this analysis, act genotyping does not provide additional information about an individual's risk of alzheimer's disease beyond the risk information conferred by apoe genotype alone. |
1997-06-18 |
2023-08-12 |
Not clear |
| E Nishiyama, N Iwamoto, J Ohwada, H Ara. Distribution of apolipoprotein E in senile plaques in brains with Alzheimer's disease: investigation with the confocal laser scan microscope. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098525. |
in order to elucidate the mechanism of the occurrence of apolipoprotein e (apoe) in senile plaques (sp) in the brain of alzheimer's disease (ad) patients, we morphologically examined double immunofluorescent-stained sections by scanning with the confocal laser scan microscope (lsm) and reconstructed their three-dimensional structure by a computerized imaging technique. |
1997-06-17 |
2023-08-12 |
Not clear |
| D C Steffens, B L Plassman, M J Helms, K A Welsh-Bohmer, A M Saunders, J C Breitne. A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease. Biological psychiatry. vol 41. issue 8. 1997-06-17. PMID:9099411. |
a prior history of depression and the epsilon 4 allele of apolipoprotein e (apoe) have each been associated with development of alzheimer's disease (ad). |
1997-06-17 |
2023-08-12 |
Not clear |
| F Baskin, G M Smith, J A Fosmire, R N Rosenber. Altered apolipoprotein E secretion in cytokine treated human astrocyte cultures. Journal of the neurological sciences. vol 148. issue 1. 1997-06-16. PMID:9125385. |
the combination of these cytokine effects in chronically degenerating brain regions of alzheimer's disease and other neurodegenerative diseases could reduce the amount of apoe available for neuronal regeneration. |
1997-06-16 |
2023-08-12 |
human |
| K Tsuzuki, R Fukatsu, Y Takamaru, T Yoshida, Y Hayashi, K Kobayashi, N Fujii, N Takahat. Snake coiled fibres in rat soleus muscle in chloroquine induced myopathy share immunohistochemical characteristics with amyloid depositions in Alzheimer's disease brain tissue. International journal of experimental pathology. vol 78. issue 1. 1997-06-13. PMID:9166100. |
immunopathological studies demonstrated that the amyloid beta (a beta) and n and c-terminal regions of amyloid precursor protein (app), and the amyloid associated proteins tested, apolipoprotein e (apoe), sp-40,40, alpha 1-antichymotrypsin (alpha 1-act), and ubiquitin, which are known to be components of amyloid depositions found in alzheimer's disease (ad) affected brains, were present in the scf. |
1997-06-13 |
2023-08-12 |
rat |
| K Taddei, R Clarnette, S E Gandy, R N Martin. Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease. Neuroscience letters. vol 223. issue 1. 1997-06-12. PMID:9058415. |
increased plasma apolipoprotein e (apoe) levels in alzheimer's disease. |
1997-06-12 |
2023-08-12 |
human |
| K Taddei, R Clarnette, S E Gandy, R N Martin. Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease. Neuroscience letters. vol 223. issue 1. 1997-06-12. PMID:9058415. |
we measured the concentration of apolipoprotein e (apoe) in plasma from 184 non-fasted subjects in order to determine whether important variations might exist linking plasma apoe levels to clinical phenotypes among early and late onset sporadic alzheimer's disease (ad) and down's syndrome (ds). |
1997-06-12 |
2023-08-12 |
human |
| G M Murphy, E V Sullivan, D Gallagher-Thompson, L W Thompson, C M van Duijn, L S Forno, W G Ellis, W J Jagust, J Yesavage, J R Tinklenber. No association between the alpha 1-antichymotrypsin A allele and Alzheimer's disease. Neurology. vol 48. issue 5. 1997-06-11. PMID:9153464. |
the alpha 1-antichymotrypsin (act) a allele was recently associated with alzheimer's disease (ad), and the act aa genotype was reported to be more frequent in ad subjects with the apolipoprotein e (apoe) epsilon4 allele. |
1997-06-11 |
2023-08-12 |
human |
| A Merched, H Blain, S Visvikis, B Herbeth, C Jeandel, G Sies. Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease. Journal of the neurological sciences. vol 145. issue 1. 1997-06-09. PMID:9073026. |
worldwide evidence has recently shown that the allele epsilon4 of apolipoprotein e (apoe) is a genetic risk factor for alzheimer's disease (ad) underlining the possible role of apoe in the physiopathology of ad. |
1997-06-09 |
2023-08-12 |
Not clear |
| S Hahne, C Nordstedt, A Ahlin, H Nybäc. Levels of cerebrospinal fluid apolipoprotein E in patients with Alzheimer's disease and healthy controls. Neuroscience letters. vol 224. issue 2. 1997-06-09. PMID:9086466. |
one isoform of apolipoprotein e (apoe), a protein primarily involved in transport of lipids, is associated with an increased risk for alzheimer's disease. |
1997-06-09 |
2023-08-12 |
Not clear |
| S Hahne, C Nordstedt, A Ahlin, H Nybäc. Levels of cerebrospinal fluid apolipoprotein E in patients with Alzheimer's disease and healthy controls. Neuroscience letters. vol 224. issue 2. 1997-06-09. PMID:9086466. |
levels of full-length apoe in cerebrospinal fluid from 13 alzheimer patients and 12 healthy controls were determined using western blotting technique. |
1997-06-09 |
2023-08-12 |
Not clear |
| S Hahne, C Nordstedt, A Ahlin, H Nybäc. Levels of cerebrospinal fluid apolipoprotein E in patients with Alzheimer's disease and healthy controls. Neuroscience letters. vol 224. issue 2. 1997-06-09. PMID:9086466. |
hence, it is concluded that increases in cerebrospinal fluid (csf) levels of apoe are not involved in the pathogenesis of alzheimer's disease and that measurement of csf apoe levels does not seem to be useful as a diagnostic procedure. |
1997-06-09 |
2023-08-12 |
Not clear |
| M R Farlo. Alzheimer's disease: clinical implications of the apolipoprotein E genotype. Neurology. vol 48. issue 5 Suppl 6. 1997-06-09. PMID:9153158. |
inheritance of the apolipoprotein e (apoe = gene; apoe = protein) epsilon 4 gene is associated with a higher risk for development of alzheimer's disease (ad) and for occurrence of this illness at a younger age. |
1997-06-09 |
2023-08-12 |
Not clear |
| Y Stern, J Brandt, M Albert, D M Jacobs, X Liu, K Bell, K Marder, M Sano, S Albert, C Del-Castillo Castenada, F Bylsma, B Tycko, R Mayeu. The absence of an apolipoprotein epsilon4 allele is associated with a more aggressive form of Alzheimer's disease. Annals of neurology. vol 41. issue 5. 1997-06-03. PMID:9153523. |
we investigated the relationship between apoe genotype and rate of disease progression and survival in 99 patients with probable alzheimer's disease (ad) who were followed biannually for up to 6 years. |
1997-06-03 |
2023-08-12 |
Not clear |