| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Vitek, J Snell, H Dawson, C A Colto. Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide. Biochemical and biophysical research communications. vol 240. issue 2. 1997-12-23. PMID:9388488. |
since alzheimer's is strongly associated with the presence of an apoe4 allele, our study predicts a mechanism where apoe and a beta regulate nitric oxide production in human brain. |
1997-12-23 |
2023-08-12 |
mouse |
| J C Lambert, J Pérez-Tur, M J Dupire, D Galasko, D Mann, P Amouyel, J Hardy, A Delacourte, M C Chartier-Harli. Distortion of allelic expression of apolipoprotein E in Alzheimer's disease. Human molecular genetics. vol 6. issue 12. 1997-12-19. PMID:9328480. |
the apoe epsilon4 allele is a strong genetic susceptibility factor for alzheimer's disease. |
1997-12-19 |
2023-08-12 |
Not clear |
| V P Prasher, T A Chowdhury, B R Rowe, S C Bai. ApoE genotype and Alzheimer's disease in adults with Down syndrome: meta-analysis. American journal of mental retardation : AJMR. vol 102. issue 2. 1997-12-15. PMID:9327086. |
apoe genotype and alzheimer's disease in adults with down syndrome: meta-analysis. |
1997-12-15 |
2023-08-12 |
human |
| V P Prasher, T A Chowdhury, B R Rowe, S C Bai. ApoE genotype and Alzheimer's disease in adults with Down syndrome: meta-analysis. American journal of mental retardation : AJMR. vol 102. issue 2. 1997-12-15. PMID:9327086. |
although no significant association between possession of the apoe epsilon 4 allele and onset of alzheimer's disease was found, subjects with the allele had a tendency towards lower age of onset of dementia. |
1997-12-15 |
2023-08-12 |
human |
| Y Igeta, T Kawarabayashi, M Sato, N Yamada, E Matsubara, K Ishiguro, M Kanai, Y Tomidokoro, J Osuga, K Okamoto, S Hirai, M Shoj. Apolipoprotein E accumulates with the progression of A beta deposition in transgenic mice. Journal of neuropathology and experimental neurology. vol 56. issue 11. 1997-12-10. PMID:9370233. |
to study the role of apolipoprotein e (apoe) in vivo in deposits of amyloid beta protein (a beta), a major component of senile plaque amyloid in the brain of patients with alzheimer disease, the transgenic mice were examined by apoe immunostaining. |
1997-12-10 |
2023-08-12 |
mouse |
| Y Igeta, T Kawarabayashi, M Sato, N Yamada, E Matsubara, K Ishiguro, M Kanai, Y Tomidokoro, J Osuga, K Okamoto, S Hirai, M Shoj. Apolipoprotein E accumulates with the progression of A beta deposition in transgenic mice. Journal of neuropathology and experimental neurology. vol 56. issue 11. 1997-12-10. PMID:9370233. |
these findings indicate that apoe is closely related to progression of a beta deposits with aging and suggest that a beta deposition in the transgenic pancreas is similar to that in the senile plaque of alzheimer brains. |
1997-12-10 |
2023-08-12 |
mouse |
| T Arendt, C Schindler, M K Brückner, K Eschrich, V Bigl, D Zedlick, L Marcov. Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 2. 1997-11-28. PMID:8987775. |
a relationship between the apolipoprotein e (apoe) genotype and the risk to develop alzheimer's disease has been established recently. |
1997-11-28 |
2023-08-12 |
Not clear |
| T Arendt, C Schindler, M K Brückner, K Eschrich, V Bigl, D Zedlick, L Marcov. Plastic neuronal remodeling is impaired in patients with Alzheimer's disease carrying apolipoprotein epsilon 4 allele. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 2. 1997-11-28. PMID:8987775. |
the results provide direct evidence that neuronal reorganization is affected severely in patients with alzheimer's disease carrying the apoe epsilon 4 allele. |
1997-11-28 |
2023-08-12 |
Not clear |
| P Riekkinen, H Soininen, J Partanen, A Pääkkönen, S Helisalmi, P Riekkine. The ability of THA treatment to increase cortical alpha waves is related to apolipoprotein E genotype of Alzheimer disease patients. Psychopharmacology. vol 129. issue 3. 1997-11-19. PMID:9084068. |
in a previous study, we reported that alzheimer disease (ad) patients with an apolipoprotein e (apoe) epsilon 4 allele (+ apoe4) show more severe loss of nucleus basalis (nb) cholinergic cells than patients without epsilon 4 alleles (-apoe4). |
1997-11-19 |
2023-08-12 |
Not clear |
| A E Clatworthy, T Gomez-Isla, G W Rebeck, R B Wallace, B T Hyma. Lack of association of a polymorphism in the low-density lipoprotein receptor-related protein gene with Alzheimer disease. Archives of neurology. vol 54. issue 10. 1997-11-19. PMID:9341576. |
the apolipoprotein e epsilon 4 (apoe epsilon 4) allele is associated with an increased risk for development of alzheimer disease (ad). |
1997-11-19 |
2023-08-12 |
Not clear |
| D L Spark. Coronary artery disease, hypertension, ApoE, and cholesterol: a link to Alzheimer's disease? Annals of the New York Academy of Sciences. vol 826. 1997-11-13. PMID:9329686. |
coronary artery disease, hypertension, apoe, and cholesterol: a link to alzheimer's disease? |
1997-11-13 |
2023-08-12 |
human |
| A D Roses, A M Saunder. ApoE, Alzheimer's disease, and recovery from brain stress. Annals of the New York Academy of Sciences. vol 826. 1997-11-13. PMID:9329691. |
apoe, alzheimer's disease, and recovery from brain stress. |
1997-11-13 |
2023-08-12 |
human |
| A D Roses, A M Saunder. ApoE, Alzheimer's disease, and recovery from brain stress. Annals of the New York Academy of Sciences. vol 826. 1997-11-13. PMID:9329691. |
apolipoprotein e (apoe, gene; apoe, protein) is the major genetic susceptibility locus for the common forms of alzheimer's disease (ad). |
1997-11-13 |
2023-08-12 |
human |
| K Beyer, J I Lao, L Fernández-Novoa, X A Alvarez, M A Sellers, R Cacabelo. APOE epsilon 4 allele frequency in Alzheimer's disease and vascular dementia in the Spanish population. Annals of the New York Academy of Sciences. vol 826. 1997-11-13. PMID:9329722. |
apoe epsilon 4 allele frequency in alzheimer's disease and vascular dementia in the spanish population. |
1997-11-13 |
2023-08-12 |
Not clear |
| A Sahota, M Yang, S Gao, S L Hui, O Baiyewu, O Gureje, S Oluwole, A Ogunniyi, K S Hall, H C Hendri. Apolipoprotein E-associated risk for Alzheimer's disease in the African-American population is genotype dependent. Annals of neurology. vol 42. issue 4. 1997-11-07. PMID:9382479. |
as a part of our ongoing study on alzheimer's disease (ad) in elderly african americans, we obtained clinical assessment and apolipoprotein e (apoe) genotype data on 288 individuals (including 60 with ad). |
1997-11-07 |
2023-08-12 |
Not clear |
| X Cai, D Fallin, J Stanton, P Scibelli, R Duara, F Crawford, M Mulla. APOE is linked to Alzheimer's disease in a large pedigree. American journal of medical genetics. vol 74. issue 4. 1997-11-06. PMID:9259370. |
apoe is linked to alzheimer's disease in a large pedigree. |
1997-11-06 |
2023-08-12 |
Not clear |
| R Elliott-Bryant, E S Cathcar. Apolipoprotein E and apolipoprotein A-1 knock-out mice readily develop amyloid A protein amyloidosis. Clinical immunology and immunopathology. vol 85. issue 1. 1997-11-06. PMID:9325076. |
studies have identified apolipoprotein e (apoe) ubiquitously in biochemically distinct amyloid deposits including amyloid a protein (aa) in secondary amyloidosis and amyloid beta protein (a beta) amyloid in alzheimer's disease (ad). |
1997-11-06 |
2023-08-12 |
mouse |
| L A Farrer, L A Cupples, J L Haines, B Hyman, W A Kukull, R Mayeux, R H Myers, M A Pericak-Vance, N Risch, C M van Duij. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. vol 278. issue 16. 1997-11-06. PMID:9343467. |
apoe and alzheimer disease meta analysis consortium. |
1997-11-06 |
2023-08-12 |
Not clear |
| L A Farrer, L A Cupples, J L Haines, B Hyman, W A Kukull, R Mayeux, R H Myers, M A Pericak-Vance, N Risch, C M van Duij. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. vol 278. issue 16. 1997-11-06. PMID:9343467. |
to examine more closely the association between apolipoprotein e (apoe) genotype and alzheimer disease (ad) by age and sex in populations of various ethnic and racial denominations. |
1997-11-06 |
2023-08-12 |
Not clear |
| C L Lendon, A Martinez, I M Behrens, K S Kosik, L Madrigal, J Norton, R Neuman, A Myers, F Busfield, M Wragg, M Arcos, J C Arango Viana, J Ossa, A Ruiz, A M Goate, F Loper. E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles. Human mutation. vol 10. issue 3. 1997-10-29. PMID:9298817. |
e280a ps-1 mutation causes alzheimer's disease but age of onset is not modified by apoe alleles. |
1997-10-29 |
2023-08-12 |
Not clear |