| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neill R Graff-Radford, Robert C Green, Rodney C P Go, Michael L Hutton, Timi Edeki, David Bachman, Jennifer L Adamson, Patrick Griffith, Floyd B Willis, Mary Williams, Yvonne Hipps, Jonathan L Haines, L Adrienne Cupples, Lindsay A Farre. Association between apolipoprotein E genotype and Alzheimer disease in African American subjects. Archives of neurology. vol 59. issue 4. 2002-04-19. PMID:11939894. |
the association between alzheimer disease (ad) and genotypes at the apolipoprotein e (apoe) locus has been confirmed in numerous populations worldwide, but appears to be inconsistent in african american subjects. |
2002-04-19 |
2023-08-12 |
human |
| K W Kim, J H Jhoo, J H Lee, K U Lee, D Y Lee, J C Youn, J Y Youn, J I Wo. Neither the butyrylcholinesterase K variant nor transferrin C2 variant confers a risk for Alzheimer's disease in Koreans. Journal of neural transmission (Vienna, Austria : 1996). vol 108. issue 10. 2002-04-16. PMID:11725818. |
to investigate the possible involvement of the butyrylcholinesterase (bche) k variant and transferrin (tf) c2 variant in the manifestation of alzheimer's disease (ad), we analyzed the bche, tf and apolipoprotein e (apoe) genotypes of 164 sporadic ad patients and 239 normal elderly controls. |
2002-04-16 |
2023-08-12 |
Not clear |
| Y Hashim, D Shepherd, S Wiltshire, R R Holman, J C Levy, A Clark, C A Cul. Butyrylcholinesterase K variant on chromosome 3 q is associated with Type II diabetes in white Caucasian subjects. Diabetologia. vol 44. issue 12. 2002-04-01. PMID:11793025. |
to determine the association of three genes associated with alzheimer's disease--butyrylcholinesterase (bche) on chromosome 3 q, alpha2 macroglobulin (alpha2m) on chromosome 12 p and apolipoprotein e (apoe) on chromosome 19 q--with type ii (non-insulin-dependent) diabetes mellitus. |
2002-04-01 |
2023-08-12 |
human |
| D P McLaughlin, A Sharma, A McGinley, G S Samr. The advantages of haplotype analysis of the promoter region of the human apolipoprotein E gene. Analytical biochemistry. vol 299. issue 2. 2002-03-27. PMID:11730341. |
polymorphisms in the regulatory region of the human apolipoprotein e gene (gene, apoe; protein, apoe) have been implicated in alzheimer's disease. |
2002-03-27 |
2023-08-12 |
human |
| Douglas C Ewban. Mortality differences by APOE genotype estimated from demographic synthesis. Genetic epidemiology. vol 22. issue 2. 2002-03-26. PMID:11788960. |
the 4 allele of apolipoprotein e (apoe) is associated with increased risk of two major causes of death in low-mortality populations: ischemic heart disease and alzheimer's disease. |
2002-03-26 |
2023-08-12 |
Not clear |
| J Grootendorst, E R de Kloet, S Dalm, M S Oitz. Reversal of cognitive deficit of apolipoprotein E knockout mice after repeated exposure to a common environmental experience. Neuroscience. vol 108. issue 2. 2002-03-05. PMID:11734357. |
this study tests the hypothesis that a history of common stressful experiences further promotes the cognitive deficit of apolipoprotein e (apoe)-knockout mice, an animal model to study aspects of alzheimer's disease. |
2002-03-05 |
2023-08-12 |
mouse |
| M K Lee, A J Park, B Y Nam, K J Min, B S Kee, D B Par. Apolipoprotein E genotype in Korean schizophrenic patients. Journal of Korean medical science. vol 16. issue 6. 2002-03-05. PMID:11748362. |
the apolipoprotein e (apoe) epsilon4 allele is a known risk factor for the development of alzheimer's disease, however, an association of the apoe genotype with schizophrenia is controversial. |
2002-03-05 |
2023-08-12 |
Not clear |
| K A Jellinger, W Paulus, C Wrocklage, I Litva. Effects of closed traumatic brain injury and genetic factors on the development of Alzheimer's disease. European journal of neurology. vol 8. issue 6. 2002-03-01. PMID:11784357. |
in order to assess the impact of traumatic brain injury (tbi) and apolipoprotein e (apoe) allele frequency on the development of alzheimer's disease (ad), we examined: (i) the incidence of ad pathology in 55 consecutive autopsy cases (mean age +/- sd 77.6 +/- 7.3 years) with residual closed tbi lesions and (ii) the frequency of tbi residuals in 53 age-matched autopsy proven ad cases. |
2002-03-01 |
2023-08-12 |
human |
| H Potter, I M Wefes, L N Nilsso. The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation. Neurobiology of aging. vol 22. issue 6. 2002-02-28. PMID:11755000. |
further support for a mechanistic role of inflammation in the alzheimer's disease pathogenic pathway has been provided by genetic studies, which have associated an increased risk of developing ad with specific polymorphisms in the apoe, act, and the il-1 genes. |
2002-02-28 |
2023-08-12 |
mouse |
| M Riemenschneider, M Schmolke, N Lautenschlager, H Vanderstichele, E Vanmechelen, W G Guder, A Kur. Association of CSF apolipoprotein E, Abeta42 and cognition in Alzheimer's disease. Neurobiology of aging. vol 23. issue 2. 2002-02-28. PMID:11804704. |
a significant association between csf abeta42 and cognition in patients with alzheimer's disease (ad) homozygous for the epsilon3 allele of the apolipoprotein e (apoe) has been described. |
2002-02-28 |
2023-08-12 |
human |
| Sepideh Zareparsi, Richard Camicioli, Gary Sexton, Thomas Bird, Phillip Swanson, Jeffrey Kaye, John Nutt, Haydeh Payam. Age at onset of Parkinson disease and apolipoprotein E genotypes. American journal of medical genetics. vol 107. issue 2. 2002-02-13. PMID:11807891. |
the apolipoprotein e (apoe) gene is associated with onset of alzheimer disease, and possibly other neurodegenerative disorders. |
2002-02-13 |
2023-08-12 |
Not clear |
| T Cui, X Zhou, W Jin, F Zheng, X Ca. Gene polymorphism in apolipoprotein E and presenilin-1 in patients with late-onset Alzheimer's disease. Chinese medical journal. vol 113. issue 4. 2002-02-07. PMID:11775232. |
to evaluate the association of apolipoprotein e (apoe) and presenilin-1 (ps-1) gene polymorphism with late-onset alzheimer's disease (ad). |
2002-02-07 |
2023-08-12 |
Not clear |
| Alison C Burggren, Gary W Small, Fred W Sabb, Susan Y Bookheime. Specificity of brain activation patterns in people at genetic risk for Alzheimer disease. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 10. issue 1. 2002-02-06. PMID:11790634. |
previous studies with positron-emission tomography (pet) and functional magnetic resonance imaging (fmri) have indicated differences in neural metabolism and activity between carriers of the apoe epsilon4 allele and those who are not at risk for alzheimer disease (ad). |
2002-02-06 |
2023-08-12 |
human |
| Stavra N Romas, Vincent Santana, Jennifer Williamson, Alejandra Ciappa, Joseph H Lee, Haydee Z Rondon, Pedro Estevez, Rafael Lantigua, Martin Medrano, Mayobanex Torres, Yaakov Stern, Benjamin Tycko, Richard Mayeu. Familial Alzheimer disease among Caribbean Hispanics: a reexamination of its association with APOE. Archives of neurology. vol 59. issue 1. 2002-01-31. PMID:11790235. |
familial alzheimer disease among caribbean hispanics: a reexamination of its association with apoe. |
2002-01-31 |
2023-08-12 |
Not clear |
| Stavra N Romas, Vincent Santana, Jennifer Williamson, Alejandra Ciappa, Joseph H Lee, Haydee Z Rondon, Pedro Estevez, Rafael Lantigua, Martin Medrano, Mayobanex Torres, Yaakov Stern, Benjamin Tycko, Richard Mayeu. Familial Alzheimer disease among Caribbean Hispanics: a reexamination of its association with APOE. Archives of neurology. vol 59. issue 1. 2002-01-31. PMID:11790235. |
to reexamine the association between the apolipoprotein e epsilon4 allele (apoe epsilon4) and familial alzheimer disease (ad), and to search for novel genes that may be associated with susceptibility in caribbean hispanic families with a history of ad. |
2002-01-31 |
2023-08-12 |
Not clear |
| Robert C Green, L Adrienne Cupples, Rodney Go, Kelly S Benke, Timi Edeki, Patrick A Griffith, Mary Williams, Yvonne Hipps, Neill Graff-Radford, David Bachman, Lindsay A Farre. Risk of dementia among white and African American relatives of patients with Alzheimer disease. JAMA. vol 287. issue 3. 2002-01-30. PMID:11790212. |
evidence exists that the incidence of alzheimer disease (ad), as well as risk attributable to specific genetic factors such as apolipoprotein e (apoe) genotype, may vary considerably among ethnic groups. |
2002-01-30 |
2023-08-12 |
Not clear |
| D Peng, X Xu, Y Fen. [Apolipoprotein E 4 gene is a risk factor for Alzheimer's disease]. Zhonghua nei ke za zhi. vol 40. issue 10. 2002-01-18. PMID:11769724. |
to study the association of alzheimer disease (ad) with apolipoprotein e (apoe) epsilon 4 allele and to find the biological peripheral markers for the laboratory diagnosis of ad. |
2002-01-18 |
2023-08-12 |
Not clear |
| S Yoshida, Y Iwabuchi, Y Numachi, H Saito, H Yamazaki, H Sakai, M Kimura, H Matsuoka, M Sat. Clinical features and alterations in the inferior horn sizes in lateral ventricle in Alzheimer's patients with different ApoE genotype in Japanese population. Progress in neuro-psychopharmacology & biological psychiatry. vol 25. issue 7. 2002-01-15. PMID:11513353. |
clinical features and alterations in the inferior horn sizes in lateral ventricle in alzheimer's patients with different apoe genotype in japanese population. |
2002-01-15 |
2023-08-12 |
Not clear |
| S Yoshida, Y Iwabuchi, Y Numachi, H Saito, H Yamazaki, H Sakai, M Kimura, H Matsuoka, M Sat. Clinical features and alterations in the inferior horn sizes in lateral ventricle in Alzheimer's patients with different ApoE genotype in Japanese population. Progress in neuro-psychopharmacology & biological psychiatry. vol 25. issue 7. 2002-01-15. PMID:11513353. |
e4 allele of apolipoprotein e (apoe) is considered to be not only a risk factor for alzheimer's disease (ad) but also a determinant of clinical features in ad. |
2002-01-15 |
2023-08-12 |
Not clear |
| H R Morris, A Schrag, U Nath, D Burn, N P Quinn, S Daniel, N W Wood, A J Lee. Effect of ApoE and tau on age of onset of progressive supranuclear palsy and multiple system atrophy. Neuroscience letters. vol 312. issue 2. 2002-01-15. PMID:11595348. |
the apoe epsilon4 allele is associated with an earlier age of onset of sporadic and familial alzheimer's disease. |
2002-01-15 |
2023-08-12 |
Not clear |