| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hélène G Bazin, Marcos A Marques, Albert P Owens, Robert J Linhardt, Keith A Crutche. Inhibition of apolipoprotein E-related neurotoxicity by glycosaminoglycans and their oligosaccharides. Biochemistry. vol 41. issue 25. 2002-07-12. PMID:12069613. |
apolipoprotein e (apoe) has been genetically linked to late-onset alzheimer's disease (ad). |
2002-07-12 |
2023-08-12 |
Not clear |
| Bruno Copin, Antoine P Brézin, Françoise Valtot, Jean-Claude Dascotte, Alain Béchetoille, Henri-Jean Garcho. Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene. American journal of human genetics. vol 70. issue 6. 2002-06-27. PMID:11992263. |
apolipoprotein e (apoe) plays an essential role in lipid metabolism, and the apoe gene has been involved in neuronal degeneration that occurs in alzheimer disease (ad). |
2002-06-27 |
2023-08-12 |
Not clear |
| M Cecilia Ljungberg, Rejith Dayanandan, Ayodeji Asuni, Tom H Rupniak, Brian H Anderton, Simon Loveston. Truncated apoE forms tangle-like structures in a neuronal cell line. Neuroreport. vol 13. issue 6. 2002-06-26. PMID:11997703. |
apolipoprotein e is the predominant brain lipoprotein and polymorphic variation in the apoe gene the major genetic susceptibly factor for late onset alzheimer's disease (ad). |
2002-06-26 |
2023-08-12 |
mouse |
| Hideki Hayashi, Urule Igbavboa, Hiroki Hamanaka, Mariko Kobayashi, Shinobu C Fujita, W Gibson Wood, Katsuhiko Yanagisaw. Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. Neuroreport. vol 13. issue 4. 2002-06-24. PMID:11930145. |
inheritance of the apolipoprotein (apoe) epsilon4 allele is a risk factor for developing alzheimer's disease (ad). |
2002-06-24 |
2023-08-12 |
mouse |
| Bozena Mazur-Kolecka, Janusz Frackowiak, Dagmar Kowal, Jolanta Krzeslowska, Dennis Dickso. Oxidative protein damage in cells engaged in beta-amyloidosis is related to apoE genotype. Neuroreport. vol 13. issue 4. 2002-06-24. PMID:11930162. |
the epsilon4 allele of apolipoprotein e (apoe) is a risk factor for alzheimer's disease. |
2002-06-24 |
2023-08-12 |
human |
| Liisa Myllykangas, Tuomo Polvikoski, Karoliina Reunanen, Fabienne Wavrant-De Vrieze, Clare Ellis, Dena Hernandez, Raimo Sulkava, Kimmo Kontula, Auli Verkkoniemi, Irma-Leena Notkola, John Hardy, Jordi Perez-Tur, Matti J Haltia, Pentti J Tienar. ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain. American journal of medical genetics. vol 114. issue 3. 2002-06-17. PMID:11920850. |
apoe epsilon3-haplotype modulates alzheimer beta-amyloid deposition in the brain. |
2002-06-17 |
2023-08-12 |
human |
| Liisa Myllykangas, Tuomo Polvikoski, Karoliina Reunanen, Fabienne Wavrant-De Vrieze, Clare Ellis, Dena Hernandez, Raimo Sulkava, Kimmo Kontula, Auli Verkkoniemi, Irma-Leena Notkola, John Hardy, Jordi Perez-Tur, Matti J Haltia, Pentti J Tienar. ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain. American journal of medical genetics. vol 114. issue 3. 2002-06-17. PMID:11920850. |
apoe epsilon4 allele increases the risk of late-onset alzheimer disease (ad) as well as the amount of beta-amyloid deposition in the brain. |
2002-06-17 |
2023-08-12 |
human |
| Abbas Parsian, Brad Racette, L Jane Goldsmith, Joel S Perlmutte. Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset. Genomics. vol 79. issue 3. 2002-06-04. PMID:11863377. |
apolipoprotein e (apoe) allele epsilon4 has been associated with familial and sporadic late-onset senile dementia of the alzheimer's type. |
2002-06-04 |
2023-08-12 |
Not clear |
| D Curtis, B V North, P C Sha. A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. Annals of human genetics. vol 65. issue Pt 5. 2002-05-14. PMID:11806855. |
an example application is presented for genome scan data on alzheimer's disease with analysis conditional on apoliprotein e (apoe) genotypes. |
2002-05-14 |
2023-08-12 |
human |
| K W Kim, J H Jhoo, J H Lee, D Y Lee, K U Lee, J C Youn, J Y Youn, J I Wo. The domain-specific, stage-limited impact of the apolipoprotein E epsilon-4 allele on cognitive functions in Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 13. issue 3. 2002-05-09. PMID:11893834. |
to examine the impact of the apoe epsilon4 allele on the cognitive functions of alzheimer's disease (ad) patients, we administered the eight neuropsychological tests from the consortium to establish a registry for alzheimer's disease neuropsychological assessment battery to 118 korean ad patients. |
2002-05-09 |
2023-08-12 |
Not clear |
| Elizbieta Luczywek, Anna Nowicka, Anna Pfeffer, Krzysztof Czyzewski, Maria Styczyńska, Maciej Lałowski, Maria Barcikowsk. Cognitive deficits and polymorphism of apolipoprotein E in Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 13. issue 3. 2002-05-09. PMID:11893839. |
the aim of this study was to test the relationship between apolipoprotein e (apoe) genotypes and patterns of cognitive deficits in alzheimer's disease (ad). |
2002-05-09 |
2023-08-12 |
human |
| W Burke, L E Pinsky, N A Pres. Categorizing genetic tests to identify their ethical, legal, and social implications. American journal of medical genetics. vol 106. issue 3. 2002-05-07. PMID:11778984. |
conversely, many geneticists recommend against testing for apolipoprotein e (apoe) alleles to predict alzheimer disease (ad) risk. |
2002-05-07 |
2023-08-12 |
Not clear |
| D M Holtzma. Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy. Journal of molecular neuroscience : MN. vol 17. issue 2. 2002-05-07. PMID:11816788. |
the epsilon4 allele of apolipoprotein e (apoe) is a risk factor for alzheimer's disease (ad) and cerebral amyloid angiopathy (caa). |
2002-05-07 |
2023-08-12 |
mouse |
| G Dal Forno, K A Carson, R Brookmeyer, J Troncoso, C H Kawas, J Brand. APOE genotype and survival in men and women with Alzheimer's disease. Neurology. vol 58. issue 7. 2002-05-07. PMID:11940690. |
apoe genotype and survival in men and women with alzheimer's disease. |
2002-05-07 |
2023-08-12 |
Not clear |
| N Scarmeas, J Brandt, M Albert, D P Devanand, K Marder, K Bell, A Ciappa, B Tycko, Y Ster. Association between the APOE genotype and psychopathologic symptoms in Alzheimer's disease. Neurology. vol 58. issue 8. 2002-05-07. PMID:11971084. |
association between the apoe genotype and psychopathologic symptoms in alzheimer's disease. |
2002-05-07 |
2023-08-12 |
Not clear |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
polymorphisms within the genes encoding apolipoprotein e (apoe), apolipoprotein ci (apoci), alpha1-antichymotrypsin (act), the low-density lipoprotein (ldl) receptor and lipoprotein lipase were investigated in patients suffering from alzheimer's dementia and non-demented psychiatric patients as control subjects. |
2002-05-02 |
2023-08-12 |
human |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
the apoe allele 4, well known as a risk factor in alzheimer's disease, and the apoci allele a2, which is closely linked to the apoe allele 4, were found elevated in the index group. |
2002-05-02 |
2023-08-12 |
human |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
we conclude that, apart from the apoe allele 4, other genetically regulated factors like apoci and the ldl receptor modulate the individual risk for alzheimer's disease. |
2002-05-02 |
2023-08-12 |
human |
| Dylan G Harwood, Warren W Barker, Raymond L Ownby, Michael Mullan, Ranjan Duar. Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling elderly sample. Alzheimer disease and associated disorders. vol 16. issue 1. 2002-04-30. PMID:11882744. |
the epsilon 4 (epsilon 4) and epsilon 2 (epsilon 2) alleles of the apolipoprotein gene (apoe) located on chromosome 19 have been associated with increased and decreased risk for alzheimer disease (ad) in older adults, respectively. |
2002-04-30 |
2023-08-12 |
Not clear |
| Z Janka, A Juhász, A Rimanóczy A, K Boda, J Márki-Zay, J Kálmá. Codon 311 (Cys --> Ser) polymorphism of paraoxonase-2 gene is associated with apolipoprotein E4 allele in both Alzheimer's and vascular dementias. Molecular psychiatry. vol 7. issue 1. 2002-04-19. PMID:11803456. |
(3-8) the importance of cardiovascular risk factors in the pathomechanism of alzheimer's disease (ad) and vascular dementia (vd)(9-13) prompted us to examine the genetic effect of pon2 gene codon 311 (cys-->ser; pon2*s) polymorphism and the relationship between the pon2*s allele and the other dementia risk factor, the apoe polymorphism in these dementias. |
2002-04-19 |
2023-08-12 |
Not clear |