| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J-C Lambert, L Araria-Goumidi, L Myllykangas, C Ellis, J C Wang, M J Bullido, J M Harris, M J Artiga, D Hernandez, J M Kwon, B Frigard, R C Petersen, A M Cumming, F Pasquier, I Sastre, P J Tienari, A Frank, R Sulkava, J C Morris, D St Clair, D M Mann, F Wavrant-DeVrièze, M Ezquerra-Trabalon, P Amouyel, J Hardy, M Haltia, F Valdivieso, A M Goate, J Pérez-Tur, C L Lendon, M-C Chartier-Harli. Contribution of APOE promoter polymorphisms to Alzheimer's disease risk. Neurology. vol 59. issue 1. 2002-07-25. PMID:12105308. |
contribution of apoe promoter polymorphisms to alzheimer's disease risk. |
2002-07-25 |
2023-08-12 |
Not clear |
| Barbara Borroni, Francesca Colciaghi, Lucia Pastorino, Silvana Archetti, Paola Corsini, Flaminio Cattabeni, Monica Di Luca, Alessandro Padovan. ApoE genotype influences the biological effect of donepezil on APP metabolism in Alzheimer disease: evidence from a peripheral model. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 3. 2002-07-16. PMID:12007670. |
apoe genotype influences the biological effect of donepezil on app metabolism in alzheimer disease: evidence from a peripheral model. |
2002-07-16 |
2023-08-12 |
human |
| Hélène G Bazin, Marcos A Marques, Albert P Owens, Robert J Linhardt, Keith A Crutche. Inhibition of apolipoprotein E-related neurotoxicity by glycosaminoglycans and their oligosaccharides. Biochemistry. vol 41. issue 25. 2002-07-12. PMID:12069613. |
apolipoprotein e (apoe) has been genetically linked to late-onset alzheimer's disease (ad). |
2002-07-12 |
2023-08-12 |
Not clear |
| Bruno Copin, Antoine P Brézin, Françoise Valtot, Jean-Claude Dascotte, Alain Béchetoille, Henri-Jean Garcho. Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene. American journal of human genetics. vol 70. issue 6. 2002-06-27. PMID:11992263. |
apolipoprotein e (apoe) plays an essential role in lipid metabolism, and the apoe gene has been involved in neuronal degeneration that occurs in alzheimer disease (ad). |
2002-06-27 |
2023-08-12 |
Not clear |
| M Cecilia Ljungberg, Rejith Dayanandan, Ayodeji Asuni, Tom H Rupniak, Brian H Anderton, Simon Loveston. Truncated apoE forms tangle-like structures in a neuronal cell line. Neuroreport. vol 13. issue 6. 2002-06-26. PMID:11997703. |
apolipoprotein e is the predominant brain lipoprotein and polymorphic variation in the apoe gene the major genetic susceptibly factor for late onset alzheimer's disease (ad). |
2002-06-26 |
2023-08-12 |
mouse |
| Hideki Hayashi, Urule Igbavboa, Hiroki Hamanaka, Mariko Kobayashi, Shinobu C Fujita, W Gibson Wood, Katsuhiko Yanagisaw. Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. Neuroreport. vol 13. issue 4. 2002-06-24. PMID:11930145. |
inheritance of the apolipoprotein (apoe) epsilon4 allele is a risk factor for developing alzheimer's disease (ad). |
2002-06-24 |
2023-08-12 |
mouse |
| Bozena Mazur-Kolecka, Janusz Frackowiak, Dagmar Kowal, Jolanta Krzeslowska, Dennis Dickso. Oxidative protein damage in cells engaged in beta-amyloidosis is related to apoE genotype. Neuroreport. vol 13. issue 4. 2002-06-24. PMID:11930162. |
the epsilon4 allele of apolipoprotein e (apoe) is a risk factor for alzheimer's disease. |
2002-06-24 |
2023-08-12 |
human |
| Liisa Myllykangas, Tuomo Polvikoski, Karoliina Reunanen, Fabienne Wavrant-De Vrieze, Clare Ellis, Dena Hernandez, Raimo Sulkava, Kimmo Kontula, Auli Verkkoniemi, Irma-Leena Notkola, John Hardy, Jordi Perez-Tur, Matti J Haltia, Pentti J Tienar. ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain. American journal of medical genetics. vol 114. issue 3. 2002-06-17. PMID:11920850. |
apoe epsilon3-haplotype modulates alzheimer beta-amyloid deposition in the brain. |
2002-06-17 |
2023-08-12 |
human |
| Liisa Myllykangas, Tuomo Polvikoski, Karoliina Reunanen, Fabienne Wavrant-De Vrieze, Clare Ellis, Dena Hernandez, Raimo Sulkava, Kimmo Kontula, Auli Verkkoniemi, Irma-Leena Notkola, John Hardy, Jordi Perez-Tur, Matti J Haltia, Pentti J Tienar. ApoE epsilon3-haplotype modulates Alzheimer beta-amyloid deposition in the brain. American journal of medical genetics. vol 114. issue 3. 2002-06-17. PMID:11920850. |
apoe epsilon4 allele increases the risk of late-onset alzheimer disease (ad) as well as the amount of beta-amyloid deposition in the brain. |
2002-06-17 |
2023-08-12 |
human |
| Abbas Parsian, Brad Racette, L Jane Goldsmith, Joel S Perlmutte. Parkinson's disease and apolipoprotein E: possible association with dementia but not age at onset. Genomics. vol 79. issue 3. 2002-06-04. PMID:11863377. |
apolipoprotein e (apoe) allele epsilon4 has been associated with familial and sporadic late-onset senile dementia of the alzheimer's type. |
2002-06-04 |
2023-08-12 |
Not clear |
| D Curtis, B V North, P C Sha. A novel method of two-locus linkage analysis applied to a genome scan for late onset Alzheimer's disease. Annals of human genetics. vol 65. issue Pt 5. 2002-05-14. PMID:11806855. |
an example application is presented for genome scan data on alzheimer's disease with analysis conditional on apoliprotein e (apoe) genotypes. |
2002-05-14 |
2023-08-12 |
human |
| K W Kim, J H Jhoo, J H Lee, D Y Lee, K U Lee, J C Youn, J Y Youn, J I Wo. The domain-specific, stage-limited impact of the apolipoprotein E epsilon-4 allele on cognitive functions in Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 13. issue 3. 2002-05-09. PMID:11893834. |
to examine the impact of the apoe epsilon4 allele on the cognitive functions of alzheimer's disease (ad) patients, we administered the eight neuropsychological tests from the consortium to establish a registry for alzheimer's disease neuropsychological assessment battery to 118 korean ad patients. |
2002-05-09 |
2023-08-12 |
Not clear |
| Elizbieta Luczywek, Anna Nowicka, Anna Pfeffer, Krzysztof Czyzewski, Maria Styczyńska, Maciej Lałowski, Maria Barcikowsk. Cognitive deficits and polymorphism of apolipoprotein E in Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 13. issue 3. 2002-05-09. PMID:11893839. |
the aim of this study was to test the relationship between apolipoprotein e (apoe) genotypes and patterns of cognitive deficits in alzheimer's disease (ad). |
2002-05-09 |
2023-08-12 |
human |
| W Burke, L E Pinsky, N A Pres. Categorizing genetic tests to identify their ethical, legal, and social implications. American journal of medical genetics. vol 106. issue 3. 2002-05-07. PMID:11778984. |
conversely, many geneticists recommend against testing for apolipoprotein e (apoe) alleles to predict alzheimer disease (ad) risk. |
2002-05-07 |
2023-08-12 |
Not clear |
| D M Holtzma. Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy. Journal of molecular neuroscience : MN. vol 17. issue 2. 2002-05-07. PMID:11816788. |
the epsilon4 allele of apolipoprotein e (apoe) is a risk factor for alzheimer's disease (ad) and cerebral amyloid angiopathy (caa). |
2002-05-07 |
2023-08-12 |
mouse |
| G Dal Forno, K A Carson, R Brookmeyer, J Troncoso, C H Kawas, J Brand. APOE genotype and survival in men and women with Alzheimer's disease. Neurology. vol 58. issue 7. 2002-05-07. PMID:11940690. |
apoe genotype and survival in men and women with alzheimer's disease. |
2002-05-07 |
2023-08-12 |
Not clear |
| N Scarmeas, J Brandt, M Albert, D P Devanand, K Marder, K Bell, A Ciappa, B Tycko, Y Ster. Association between the APOE genotype and psychopathologic symptoms in Alzheimer's disease. Neurology. vol 58. issue 8. 2002-05-07. PMID:11971084. |
association between the apoe genotype and psychopathologic symptoms in alzheimer's disease. |
2002-05-07 |
2023-08-12 |
Not clear |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
polymorphisms within the genes encoding apolipoprotein e (apoe), apolipoprotein ci (apoci), alpha1-antichymotrypsin (act), the low-density lipoprotein (ldl) receptor and lipoprotein lipase were investigated in patients suffering from alzheimer's dementia and non-demented psychiatric patients as control subjects. |
2002-05-02 |
2023-08-12 |
human |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
the apoe allele 4, well known as a risk factor in alzheimer's disease, and the apoci allele a2, which is closely linked to the apoe allele 4, were found elevated in the index group. |
2002-05-02 |
2023-08-12 |
human |
| W Retz, J Thome, N Durany, A Harsányi, P Retz-Junginger, J Kornhuber, P Riederer, M Rösle. Potential genetic markers of sporadic Alzheimer's dementia. Psychiatric genetics. vol 11. issue 3. 2002-05-02. PMID:11702052. |
we conclude that, apart from the apoe allele 4, other genetically regulated factors like apoci and the ldl receptor modulate the individual risk for alzheimer's disease. |
2002-05-02 |
2023-08-12 |
human |