| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Al-Shammari, H Fatania, R Al-Radwan, A O Akanj. Apolipoprotein E polymorphism and lipoprotein levels in a Gulf Arab population in Kuwait: a pilot study. Annals of Saudi medicine. vol 24. issue 5. 2005-02-15. PMID:15573849. |
apoe polymorphism is believed to confer susceptibility to coronary heart disease (chd) and alzheimer's disease. |
2005-02-15 |
2023-08-12 |
Not clear |
| M Farlow, R Lane, S Kudaravalli, Y H. Differential qualitative responses to rivastigmine in APOE epsilon 4 carriers and noncarriers. The pharmacogenomics journal. vol 4. issue 5. 2005-02-11. PMID:15289797. |
however, at 26 weeks, placebo-treated apoe epsilon4 patients declined 3.04 points below baseline on the cognitive subscale of the alzheimer's disease assessment scale (adas-cog), and rivastigmine-treated patients improved by 1.67 points. |
2005-02-11 |
2023-08-12 |
Not clear |
| L Mosconi, K Herholz, I Prohovnik, B Nacmias, M T R De Cristofaro, M Fayyaz, L Bracco, S Sorbi, A Pup. Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: implications for brain reserve. Journal of neurology, neurosurgery, and psychiatry. vol 76. issue 1. 2005-02-08. PMID:15607989. |
metabolic interaction between apoe genotype and onset age in alzheimer's disease: implications for brain reserve. |
2005-02-08 |
2023-08-12 |
Not clear |
| L Mosconi, K Herholz, I Prohovnik, B Nacmias, M T R De Cristofaro, M Fayyaz, L Bracco, S Sorbi, A Pup. Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: implications for brain reserve. Journal of neurology, neurosurgery, and psychiatry. vol 76. issue 1. 2005-02-08. PMID:15607989. |
clinically apparent alzheimer's disease (ad) is thought to result when brain tissue damage exceeds a critical threshold of "brain reserve", a process possibly accelerated by the apolipoprotein e (apoe) e4 allele. |
2005-02-08 |
2023-08-12 |
Not clear |
| Tomislav Babić, Darija Mahović Lakusić, Jadranka Sertić, Mladen Petrovecki, Ana Stavljenić-Rukavin. ApoE genotyping and response to galanthamine in Alzheimer's disease--a real life retrospective study. Collegium antropologicum. vol 28. issue 1. 2005-02-03. PMID:15636076. |
apoe genotyping and response to galanthamine in alzheimer's disease--a real life retrospective study. |
2005-02-03 |
2023-08-12 |
Not clear |
| Tomislav Babić, Darija Mahović Lakusić, Jadranka Sertić, Mladen Petrovecki, Ana Stavljenić-Rukavin. ApoE genotyping and response to galanthamine in Alzheimer's disease--a real life retrospective study. Collegium antropologicum. vol 28. issue 1. 2005-02-03. PMID:15636076. |
this study was undertaken to evaluate the effect of galanthamine, a new cholinesterase inhibitor on cognitive performances in 84 patients with various apoe genotype and alzheimer's disease (ad) during the six-month treatment. |
2005-02-03 |
2023-08-12 |
Not clear |
| Camillo Marra, Alessandra Bizzarro, Antonio Daniele, Lara De Luca, Monica Ferraccioli, Alessandro Valenza, Christina Brahe, Francesco Danilo Tiziano, Guido Gainotti, Carlo Masull. Apolipoprotein E epsilon4 allele differently affects the patterns of neuropsychological presentation in early- and late-onset Alzheimer's disease patients. Dementia and geriatric cognitive disorders. vol 18. issue 2. 2005-02-02. PMID:15211066. |
the presence of the apolipoprotein e (apoe) epsilon4 allele is a definite risk factor for the onset of alzheimer's disease (ad). |
2005-02-02 |
2023-08-12 |
human |
| V R M Lombardi, L Fernández-Novoa, I Etcheverria, S Seoane, R Cacabelo. Association between APOE epsilon4 allele and increased expression of CD95 on T cells from patients with Alzheimer's disease. Methods and findings in experimental and clinical pharmacology. vol 26. issue 7. 2005-02-02. PMID:15538542. |
association between apoe epsilon4 allele and increased expression of cd95 on t cells from patients with alzheimer's disease. |
2005-02-02 |
2023-08-12 |
Not clear |
| Dylan G Harwood, Warren W Barker, Raymond L Ownby, Peter St George-Hyslop, Michael Mullan, Ranjan Duar. Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample. International psychogeriatrics. vol 16. issue 3. 2005-02-01. PMID:15559755. |
this study examined the association between the apolipoprotein-e epsilon4 allele (apoe epsilon4) and age of disease onset in a bi-ethnic sample of community dwelling alzheimer's disease (ad) patients. |
2005-02-01 |
2023-08-12 |
Not clear |
| Trey Sunderland, Nadeem Mirza, Karen T Putnam, Gary Linker, Deepa Bhupali, Rob Durham, Holly Soares, Lida Kimmel, David Friedman, Judy Bergeson, Gyorgy Csako, James A Levy, John J Bartko, Robert M Cohe. Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele. Biological psychiatry. vol 56. issue 9. 2005-01-31. PMID:15522251. |
cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for alzheimer's disease: the effect of apoe epsilon4 allele. |
2005-01-31 |
2023-08-12 |
human |
| L Adrienne Cupples, Lindsay A Farrer, A Dessa Sadovnick, Norman Relkin, Peter Whitehouse, Robert C Gree. Estimating risk curves for first-degree relatives of patients with Alzheimer's disease: the REVEAL study. Genetics in medicine : official journal of the American College of Medical Genetics. vol 6. issue 4. 2005-01-24. PMID:15266206. |
the reveal study is a randomized, controlled study of the psychological and behavioral impact of apoe disclosure in a risk assessment protocol provided to first degree relatives of patients with alzheimer's disease. |
2005-01-24 |
2023-08-12 |
Not clear |
| J Scott Roberts, Melissa Barber, Tamsen M Brown, L Adrienne Cupples, Lindsay A Farrer, Susan A LaRusse, Stephen G Post, Kimberly A Quaid, Lisa D Ravdin, Norman R Relkin, A Dessa Sadovnick, Peter J Whitehouse, John L Woodard, Robert C Gree. Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial. Genetics in medicine : official journal of the American College of Medical Genetics. vol 6. issue 4. 2005-01-24. PMID:15266207. |
alzheimer's disease, for which one form of the apolipoprotein e (apoe) genotype is a risk factor, provides a paradigm in which to examine response to susceptibility testing for common, complex diseases. |
2005-01-24 |
2023-08-12 |
Not clear |
| Hiroyuki W Kitamura, Hiroki Hamanaka, Masahiko Watanabe, Koji Wada, Chiharu Yamazaki, Shinobu C Fujita, Toshiya Manabe, Nobuyuki Nukin. Age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein E4 instead of mouse apolipoprotein E. Neuroscience letters. vol 369. issue 3. 2005-01-13. PMID:15464259. |
age-dependent enhancement of hippocampal long-term potentiation in knock-in mice expressing human apolipoprotein e4 instead of mouse apolipoprotein e. human apolipoprotein e (apoe) comprises three isoforms, apoe2, apoe3 and apoe4, and apoe4 has been reported as a risk factor of alzheimer's disease (ad). |
2005-01-13 |
2023-08-12 |
mouse |
| János Kálmán, Anna Juhász, Agnes Rimanóczy, András Palotás, Miklós Palotás, Krisztina Boda, János Márki-Zay, Eva Csibri, Zoltán Jank. The nitric oxide synthase-3 codon 298 polymorphism is not associated with late-onset sporadic Alzheimer's dementia and Lewy body disease in a sample from Hungary. Psychiatric genetics. vol 13. issue 4. 2005-01-11. PMID:14639046. |
an association study was performed between apolipoprotein e (apoe) polymorphism and the common structural polymorphism glu/asp at codon 298 of the nitric oxide synthase (nos3) gene in late-onset sporadic alzheimer's dementia probands (load), diffuse lewy body dementia cases (dlbd) and controls in a hungarian sample. |
2005-01-11 |
2023-08-12 |
Not clear |
| Wenyong Huang, Chengxuan Qiu, Eva von Strauss, Bengt Winblad, Laura Fratiglion. APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study. Archives of neurology. vol 61. issue 12. 2005-01-11. PMID:15596614. |
apoe genotype, family history of dementia, and alzheimer disease risk: a 6-year follow-up study. |
2005-01-11 |
2023-08-12 |
Not clear |
| Marcos A Marques, Phillip A Owens, Keith A Crutche. Progress toward identification of protease activity involved in proteolysis of apolipoprotein e in human brain. Journal of molecular neuroscience : MN. vol 24. issue 1. 2004-12-30. PMID:15314253. |
apolipoprotein e (apoe) genotype is the single most important genetic risk factor for the most common (sporadic) form of alzheimer's disease (ad). |
2004-12-30 |
2023-08-12 |
mouse |
| Wagner Malagó Tavares, Marcia Aparecida Sperança, Roger Willian de Labio, Clovis A Peres, Ivan Hideyo Okamoto, Paulo Henrique Ferreira Bertolucci, Marília de A C Smith, Spencer Luiz Marques Payã. Apolipoprotein E4 allele and ribosomal genes in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 6. issue 4. 2004-12-30. PMID:15345809. |
the apoe 4 allele is considered a late-onset alzheimer's disease (ad) risk factor associated with ad pathogenesis. |
2004-12-30 |
2023-08-12 |
Not clear |
| Melissa Sliger, Timothy Lander, Claire Murph. Effects of the ApoE epsilon4 allele on olfactory function in Down syndrome. Journal of Alzheimer's disease : JAD. vol 6. issue 4. 2004-12-30. PMID:15345810. |
the present study investigated the effects of the apolipoprotein e (apoe) epsilon4 allele, a risk factor for alzheimer's disease (ad), on olfactory function in down syndrome (ds). |
2004-12-30 |
2023-08-12 |
human |
| C Saft, J E Andrich, N Brune, M Gencik, P H Kraus, H Przuntek, J T Epple. Apolipoprotein E genotypes do not influence the age of onset in Huntington's disease. Journal of neurology, neurosurgery, and psychiatry. vol 75. issue 12. 2004-12-22. PMID:15548484. |
the epsilon4 allele of the apolipoprotein e (apoe) gene has been defined as a critical factor for early onset neurodegeneration in pick's, parkinson's, and alzheimer's disease. |
2004-12-22 |
2023-08-12 |
Not clear |
| Lars N G Nilsson, Gary W Arendash, Ralph E Leighty, David A Costa, Mark A Low, Marcos F Garcia, Jennifer R Cracciolo, Amyn Rojiani, Xin Wu, Kelly R Bales, Steven M Paul, Huntington Potte. Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation. Neurobiology of aging. vol 25. issue 9. 2004-12-21. PMID:15312961. |
biochemical and genetic studies indicate that the inflammatory proteins, apolipoprotein e (apoe) and alpha(1)-antichymotrypsin (act) are important in the pathogenesis of alzheimer's disease (ad). |
2004-12-21 |
2023-08-12 |
mouse |