| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Binbin Wang, Feng Jin, Ze Yang, Zeping Lu, Rui Kan, Shu Li, Chenguang Zheng, Li Wan. The insertion polymorphism in angiotensin-converting enzyme gene associated with the APOE epsilon 4 allele increases the risk of late-onset Alzheimer disease. Journal of molecular neuroscience : MN. vol 30. issue 3. 2007-05-24. PMID:17401152. |
the insertion polymorphism in angiotensin-converting enzyme gene associated with the apoe epsilon 4 allele increases the risk of late-onset alzheimer disease. |
2007-05-24 |
2023-08-12 |
human |
| Binbin Wang, Feng Jin, Ze Yang, Zeping Lu, Rui Kan, Shu Li, Chenguang Zheng, Li Wan. The insertion polymorphism in angiotensin-converting enzyme gene associated with the APOE epsilon 4 allele increases the risk of late-onset Alzheimer disease. Journal of molecular neuroscience : MN. vol 30. issue 3. 2007-05-24. PMID:17401152. |
in order to clarify the role of the polymorphism for the occurrence of load in chinese and the possibility of a synergistic effect with the apolipoprotein e allele 4 on the risk of alzheimer disease, we examined the ace and apoe genotypes in a chinese sample consisting of 104 sporadic load patients and 128 healthy controls. |
2007-05-24 |
2023-08-12 |
human |
| Keith D Coon, Amanda J Myers, David W Craig, Jennifer A Webster, John V Pearson, Diane Hu Lince, Victoria L Zismann, Thomas G Beach, Doris Leung, Leslie Bryden, Rebecca F Halperin, Lauren Marlowe, Mona Kaleem, Douglas G Walker, Rivka Ravid, Christopher B Heward, Joseph Rogers, Andreas Papassotiropoulos, Eric M Reiman, John Hardy, Dietrich A Stepha. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. The Journal of clinical psychiatry. vol 68. issue 4. 2007-05-10. PMID:17474819. |
a high-density whole-genome association study reveals that apoe is the major susceptibility gene for sporadic late-onset alzheimer's disease. |
2007-05-10 |
2023-08-12 |
Not clear |
| Keith D Coon, Amanda J Myers, David W Craig, Jennifer A Webster, John V Pearson, Diane Hu Lince, Victoria L Zismann, Thomas G Beach, Doris Leung, Leslie Bryden, Rebecca F Halperin, Lauren Marlowe, Mona Kaleem, Douglas G Walker, Rivka Ravid, Christopher B Heward, Joseph Rogers, Andreas Papassotiropoulos, Eric M Reiman, John Hardy, Dietrich A Stepha. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. The Journal of clinical psychiatry. vol 68. issue 4. 2007-05-10. PMID:17474819. |
while the apolipoprotein e (apoe) epsilon allele is a well-established risk factor for late-onset alzheimer's disease (ad), initial genome scans using microsatellite markers in late-onset ad failed to identify this locus on chromosome 19. |
2007-05-10 |
2023-08-12 |
Not clear |
| Spiridon Papapetropoulos, Matthew J Farrer, Jeremy T Stone, Nicole M Milkovic, Owen A Ross, Linda Calvo, Donald McQuorquodale, Deborah C Mas. Phenotypic associations of tau and ApoE in Parkinson's disease. Neuroscience letters. vol 414. issue 2. 2007-05-08. PMID:17204369. |
to explore possible phenotypic implications, we studied common tau and apoe gene polymorphisms, associated with alzheimer's disease (ad), progressive supranuclear palsy (psp) and pd, in a clinically and pathologically characterized cohort of pd patients and aged control subjects. |
2007-05-08 |
2023-08-12 |
human |
| Eric M Reima. Linking brain imaging and genomics in the study of Alzheimer's disease and aging. Annals of the New York Academy of Sciences. vol 1097. 2007-04-25. PMID:17413015. |
my colleagues and i have been using positron emission tomography (pet) and magnetic resonance imaging (mri) to detect and track the brain changes associated with alzheimer's disease (ad) and normal brain aging in cognitively normal persons with two copies, one copy, and no copies of the apolipoprotein e (apoe) epsilon4 allele, a common ad susceptibility gene. |
2007-04-25 |
2023-08-12 |
Not clear |
| D I Chasman, P Kozlowski, R Y Zee, D J Kwiatkowski, P M Ridke. Qualitative and quantitative effects of APOE genetic variation on plasma C-reactive protein, LDL-cholesterol, and apoE protein. Genes and immunity. vol 7. issue 3. 2007-04-24. PMID:16511556. |
in particular, the strongest link involved lower crp levels among carriers of the apoe epsilon4 allele that also contributes to the risk of cardiovascular and alzheimer's diseases as well as to higher lipid levels. |
2007-04-24 |
2023-08-12 |
Not clear |
| Rodney T Perry, Howard Wiener, Lindy E Harrell, Deborah Blacker, Rudolph E Tanzi, Lars Bertram, Susan S Bassett, Rodney C P G. Follow-up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohort. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 2. 2007-04-11. PMID:17034007. |
other than the apoe peak at 19q13, the 9q22 region was identified in our original genomic scan as the candidate region with the highest multipoint lod score (mls) in the subset of late onset alzheimer's disease (ad) families (mls = 2.9 at 101 cm) from the nimh genetics initiative sample. |
2007-04-11 |
2023-08-12 |
Not clear |
| Asad Vaisi Raygani, Zohreh Rahimi, Hadi Kharazi, Haidar Tavilani, Tayebeh Pourmotabbe. Association between apolipoprotein E polymorphism and serum lipid and apolipoprotein levels with Alzheimer's disease. Neuroscience letters. vol 408. issue 1. 2007-04-03. PMID:16997467. |
we have recently demonstrated that apolipoprotein e (apoe)-varepsilon4 allele is a risk factor for alzheimer disease (ad) in tehran, iran. |
2007-04-03 |
2023-08-12 |
human |
| Mia E-L Blomqvist, Chandra Reynolds, Hagit Katzov, Lars Feuk, Niels Andreasen, Nenad Bogdanovic, Kaj Blennow, Anthony J Brookes, Jonathan A Princ. Towards compendia of negative genetic association studies: an example for Alzheimer disease. Human genetics. vol 119. issue 1-2. 2007-04-02. PMID:16341549. |
a survey of the literature on association studies for alzheimer disease (ad) from january 2004-april 2005, identified 138 studies, 86 of which reported positive findings other than for apolipoprotein e (apoe), strongly indicative of publication bias. |
2007-04-02 |
2023-08-12 |
human |
| Zsuzsanna Hartai, Anna Juhász, Agnes Rimanóczy, Tamás Janáky, Teodóra Donkó, László Dux, Botond Penke, Gábor K Tóth, Zoltán Janka, János Kálmá. Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease. Neurochemistry international. vol 50. issue 2. 2007-03-30. PMID:17023091. |
since these members of the kynurenine pathway (kp) are proposed to be involved in the pathogenesis of alzheimer's dementia (ad), the activities of these enzymes and the levels of these metabolites were measured in the plasma and red blood cells (rbcs) of ad and control subjects together with the inheritance of the apolipoprotein (apoe) epsilon4 allele. |
2007-03-30 |
2023-08-12 |
human |
| Weili Xu, Chengxuan Qiu, Bengt Winblad, Laura Fratiglion. The effect of borderline diabetes on the risk of dementia and Alzheimer's disease. Diabetes. vol 56. issue 1. 2007-03-26. PMID:17192484. |
stratified analysis suggested a significant association between borderline diabetes and alzheimer's disease only among noncarriers of apoe epsilon4 allele. |
2007-03-26 |
2023-08-12 |
human |
| Holly C Gooding, Erin L Linnenbringer, Jeffrey Burack, J Scott Roberts, Robert C Green, Barbara B Biesecke. Genetic susceptibility testing for Alzheimer disease: motivation to obtain information and control as precursors to coping with increased risk. Patient education and counseling. vol 64. issue 1-3. 2007-03-23. PMID:16860524. |
this study investigated appraisals, including motivation, and coping preferences for undergoing apolipoprotein e (apoe) susceptibility testing for alzheimer disease (ad). |
2007-03-23 |
2023-08-12 |
Not clear |
| Barbara Borroni, Mario Grassi, Chiara Costanzi, Silvana Archetti, Luigi Caimi, Alessandro Padovan. APOE genotype and cholesterol levels in lewy body dementia and Alzheimer disease: investigating genotype-phenotype effect on disease risk. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 14. issue 12. 2007-03-22. PMID:16956959. |
apoe genotype and cholesterol levels in lewy body dementia and alzheimer disease: investigating genotype-phenotype effect on disease risk. |
2007-03-22 |
2023-08-12 |
Not clear |
| Barbara Borroni, Mario Grassi, Chiara Costanzi, Silvana Archetti, Luigi Caimi, Alessandro Padovan. APOE genotype and cholesterol levels in lewy body dementia and Alzheimer disease: investigating genotype-phenotype effect on disease risk. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 14. issue 12. 2007-03-22. PMID:16956959. |
apoe is the most recognized genetic risk factor for sporadic late-onset alzheimer disease (ad). |
2007-03-22 |
2023-08-12 |
Not clear |
| Barbara Borroni, Monica Di Luca, Alessandro Padovan. The effect of APOE genotype on clinical phenotype in Alzheimer disease. Neurology. vol 68. issue 8. 2007-03-21. PMID:17310043. |
the effect of apoe genotype on clinical phenotype in alzheimer disease. |
2007-03-21 |
2023-08-12 |
Not clear |
| W Zhou, S A Scott, S B Shelton, K A Crutche. Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease. Neuroscience. vol 143. issue 3. 2007-03-06. PMID:16997486. |
proteolysis of apolipoprotein e (apoe) may be involved in the pathogenesis of alzheimer's disease (ad). |
2007-03-06 |
2023-08-12 |
mouse |
| Uwe Beffert, Farnas Nematollah Farsian, Irene Masiulis, Robert E Hammer, Sung Ok Yoon, Klaus M Giehl, Joachim Her. ApoE receptor 2 controls neuronal survival in the adult brain. Current biology : CB. vol 16. issue 24. 2007-03-05. PMID:17174920. |
because apolipoprotein e (apoe) is a major risk factor for several neurodegenerative diseases, including alzheimer's disease , a direct or indirect role of apoe receptors in the disease process is likely. |
2007-03-05 |
2023-08-12 |
mouse |
| Sarju G Mehta, Giles D J Watts, Jennifer L Adamson, Mike Hutton, Geanie Umberger, Shuling Xiong, Sheena Ramdeen, Mark A Lovell, Virginia E Kimonis, Charles D Smit. APOE is a potential modifier gene in an autosomal dominant form of frontotemporal dementia (IBMPFD). Genetics in medicine : official journal of the American College of Medical Genetics. vol 9. issue 1. 2007-03-01. PMID:17224685. |
in this study apolipoprotein-e (apoe) was evaluated for this role in ibmpfd families based on its known modifier effect in alzheimer's disease. |
2007-03-01 |
2023-08-12 |
Not clear |
| Wiesje M van der Flier, Salka Staekenborg, Yolande A L Pijnenburg, Freek Gillissen, Rolinka Romkes, Astrid Kok, Femke H Bouwman, Philip Schelten. Apolipoprotein E genotype influences presence and severity of delusions and aggressive behavior in Alzheimer disease. Dementia and geriatric cognitive disorders. vol 23. issue 1. 2007-02-27. PMID:17077632. |
we investigated differences in the prevalence and severity of 10 neuropsychiatric and behavioral symptoms according to apolipoprotein e (apoe) genotype and dementia severity in alzheimer disease (ad). |
2007-02-27 |
2023-08-12 |
Not clear |