| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mehul A Trivedi, Taylor W Schmitz, Michele L Ries, Timothy M Hess, Michele E Fitzgerald, Craig S Atwood, Howard A Rowley, Sanjay Asthana, Mark A Sager, Sterling C Johnso. fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors for Alzheimer's disease. Neuropsychologia. vol 46. issue 6. 2008-09-24. PMID:18241895. |
in the present study, we used fmri to examine the influence of age on two other known risk factors for alzheimer's disease (ad), apoe genotype and parental history of ad (fh status), during episodic encoding (enc) and metacognitive self-appraisal (sa) paradigms. |
2008-09-24 |
2023-08-12 |
Not clear |
| Sigrid B Sando, Stacey Melquist, Ashley Cannon, Michael L Hutton, Olav Sletvold, Ingvild Saltvedt, Linda R White, Stian Lydersen, Jan O Aasl. APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway. BMC neurology. vol 8. 2008-09-24. PMID:18416843. |
apoe epsilon 4 lowers age at onset and is a high risk factor for alzheimer's disease; a case control study from central norway. |
2008-09-24 |
2023-08-12 |
Not clear |
| Sigrid B Sando, Stacey Melquist, Ashley Cannon, Michael L Hutton, Olav Sletvold, Ingvild Saltvedt, Linda R White, Stian Lydersen, Jan O Aasl. APOE epsilon 4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway. BMC neurology. vol 8. 2008-09-24. PMID:18416843. |
the apoe epsilon4 allele is the only consistently identified risk factor for late onset alzheimer's disease (load). |
2008-09-24 |
2023-08-12 |
Not clear |
| Brendan S Silbert, Lisbeth A Evered, David A Scott, Tiffany F Cowi. The apolipoprotein E epsilon4 allele is not associated with cognitive dysfunction in cardiac surgery. The Annals of thoracic surgery. vol 86. issue 3. 2008-09-19. PMID:18721571. |
the plasma protein apolipoprotein e (apoe) is a risk factor for degenerative cognitive decline manifested by mild cognitive impairment and later by alzheimer's disease. |
2008-09-19 |
2023-08-12 |
Not clear |
| Brendan S Silbert, Lisbeth A Evered, David A Scott, Tiffany F Cowi. The apolipoprotein E epsilon4 allele is not associated with cognitive dysfunction in cardiac surgery. The Annals of thoracic surgery. vol 86. issue 3. 2008-09-19. PMID:18721571. |
because both mild cognitive impairment and alzheimer's disease generally occur in elderly individuals, the age group that commonly present for cabg, we investigated if the apoe epsilon4 allele was associated with patients manifesting preexisting cognitive impairment and postoperative cognitive dysfunction. |
2008-09-19 |
2023-08-12 |
Not clear |
| Davide Seripa, Maria Giovanna Matera, Marilisa Franceschi, Antonio Daniele, Alessandra Bizzarro, Monica Rinaldi, Francesco Panza, Vito Michele Fazio, Carolina Gravina, Grazia D'Onofrio, Vincenzo Solfrizzi, Carlo Masullo, Alberto Pilott. The RELN locus in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 14. issue 3. 2008-09-17. PMID:18599960. |
reelin, a serine protease encoded by the reln gene, is part of the apolipoprotein e (apoe) biochemical pathway that is involved in the pathogenesis of alzheimer's disease (ad). |
2008-09-17 |
2023-08-12 |
Not clear |
| Mohamed Ali Smach, Bassem Charfeddine, Turkia Lammouchi, Imed Harrabi, Leila Ben Othman, Hedi Dridi, Soufien Bennamou, Khalifa Lime. CSF beta-amyloid 1-42 and tau in Tunisian patients with Alzheimer's disease: the effect of APOE epsilon4 allele. Neuroscience letters. vol 440. issue 2. 2008-09-15. PMID:18555606. |
csf beta-amyloid 1-42 and tau in tunisian patients with alzheimer's disease: the effect of apoe epsilon4 allele. |
2008-09-15 |
2023-08-12 |
human |
| Helen Christensen, Philip J Batterham, Andrew J Mackinnon, Anthony F Jorm, Holly A Mack, Karen A Mather, Kaarin J Anstey, Perminder S Sachdev, Simon Eastea. The association of APOE genotype and cognitive decline in interaction with risk factors in a 65-69 year old community sample. BMC geriatrics. vol 8. 2008-09-09. PMID:18620605. |
while the evidence of an association between the apolipoprotein e (apoe) *e4 allele and alzheimer's disease is very strong, the effect of the *e4 allele on cognitive decline in the general population is more equivocal. |
2008-09-09 |
2023-08-12 |
Not clear |
| Dietmar Rudolf Thal, W Sue T Griffin, Rob A I de Vos, Estifanos Ghebremedhi. Cerebral amyloid angiopathy and its relationship to Alzheimer's disease. Acta neuropathologica. vol 115. issue 6. 2008-08-26. PMID:18369648. |
one with capillary a beta-deposition is characterized by a strong association with the apolipoprotein e (apoe) epsilon 4 allele and by its frequent occurrence in alzheimer's disease cases whereas the other one lacking capillary a beta-deposits is not associated with apoe epsilon 4. |
2008-08-26 |
2023-08-12 |
mouse |
| Elizabeth H Corder, Kaj Blennow, Jonathan A Princ. Genetic susceptibility sets for Alzheimer's disease identified from diverse candidate loci. Rejuvenation research. vol 11. issue 3. 2008-08-21. PMID:18593285. |
alzheimer's disease (ad) has been demonstrated to be associated with gene variants of apoe, but numerous additional candidate loci exist with varying levels of statistical support. |
2008-08-21 |
2023-08-12 |
human |
| Eloy Rodríguez-Rodríguez, Javier Llorca, Ignacio Mateo, Jon Infante, Coro Sánchez-Quintana, Inés García-Gorostiaga, Carlos Fernández-Viadero, Nicolás Peña, José Berciano, Onofre Combarro. No association of genetic variants of liver X receptor-beta with Alzheimer's disease risk. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 5. 2008-08-19. PMID:18081155. |
apolipoprotein e (apoe) epsilon4 allele is the strongest hitherto known risk factor for sporadic alzheimer's disease (ad). |
2008-08-19 |
2023-08-12 |
Not clear |
| Trevor D Burt, Brian K Agan, Vincent C Marconi, Weijing He, Hemant Kulkarni, Jeffrey E Mold, Marielle Cavrois, Yadong Huang, Robert W Mahley, Matthew J Dolan, Joseph M McCune, Sunil K Ahuj. Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 25. 2008-08-19. PMID:18562290. |
these findings establish apoe as a determinant of hiv-aids pathogenesis and raise the possibility that current efforts to convert apoe4 to an "apoe3-like" molecule to treat alzheimer's disease might also have clinical applicability in hiv disease. |
2008-08-19 |
2023-08-12 |
human |
| Maire Percy, Sharon Moalem, Angeles Garcia, Martin J Somerville, Mark Hicks, David Andrews, Azar Azad, Peter Schwarz, Reza Beheshti Zavareh, Rivka Birkan, Clara Choo, Vinca Chow, Sandeep Dhaliwal, Victoria Duda, Anthony L Kupferschmidt, Kyla Lam, Deborah Lightman, Karolina Machalek, Wanna Mar, Frank Nguyen, Piotr J Rytwinski, Erin Svara, Maithy Tran, Kathleen Wheeler, Lisa Yeung, Katherine Zanibbi, Rebecca Zener, Melissa Ziraldo, Morris Freedma. Involvement of ApoE E4 and H63D in sporadic Alzheimer's disease in a folate-supplemented Ontario population. Journal of Alzheimer's disease : JAD. vol 14. issue 1. 2008-08-18. PMID:18525129. |
involvement of apoe e4 and h63d in sporadic alzheimer's disease in a folate-supplemented ontario population. |
2008-08-18 |
2023-08-12 |
human |
| Fumiko Irie, Kamal H Masaki, Helen Petrovitch, Robert D Abbott, G Webster Ross, Dennis R Taaffe, Lenore J Launer, Lon R Whit. Apolipoprotein E epsilon4 allele genotype and the effect of depressive symptoms on the risk of dementia in men: the Honolulu-Asia Aging Study. Archives of general psychiatry. vol 65. issue 8. 2008-08-15. PMID:18678795. |
the apolipoprotein e epsilon4 (apoe epsilon4) allele is a genetic risk factor for alzheimer disease. |
2008-08-15 |
2023-08-12 |
Not clear |
| F Carrillo García, E Gil Néciga, R Alberca, D García-Solís, J Millán, J J Rodríguez Uranga, E Franco, P Mir, A Suárez, R García, A Serrano-Pozo, H Pérez-Díaz, J Pol. [Apolipoprotein E4 in dementia with Lewy bodies]. Neurologia (Barcelona, Spain). vol 23. issue 3. 2008-08-11. PMID:18370334. |
there is a strong association between the e4 allele of apolipoprotein e (apoe) and alzheimer's disease (ad). |
2008-08-11 |
2023-08-12 |
Not clear |
| Lynn M Bekris, Steven P Millard, Nichole M Galloway, Simona Vuletic, John J Albers, Ge Li, Douglas R Galasko, Charles DeCarli, Martin R Farlow, Chris M Clark, Joseph F Quinn, Jeffrey A Kaye, Gerard D Schellenberg, Debby Tsuang, Elaine R Peskind, Chang-En Y. Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. Journal of Alzheimer's disease : JAD. vol 13. issue 3. 2008-08-07. PMID:18430993. |
the epsilon4 allele of the apolipoprotein e gene (apoe) is associated with increased risk and earlier age at onset in late onset alzheimer's disease (ad). |
2008-08-07 |
2023-08-12 |
human |
| Mark A Reger, G Stennis Watson, Pattie S Green, Laura D Baker, Brenna Cholerton, Mark A Fishel, Stephen R Plymate, Monique M Cherrier, Gerard D Schellenberg, William H Frey, Suzanne Craf. Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-beta in memory-impaired older adults. Journal of Alzheimer's disease : JAD. vol 13. issue 3. 2008-08-07. PMID:18430999. |
intranasal insulin administration raises central nervous system (cns) insulin levels in humans and acutely facilitates verbal memory in patients with alzheimer's disease (ad), an effect that may differ by apoe genotype. |
2008-08-07 |
2023-08-12 |
human |
| Nadezda Urosevic, Ralph N Martin. Infection and Alzheimer's disease: the APOE epsilon4 connection and lipid metabolism. Journal of Alzheimer's disease : JAD. vol 13. issue 4. 2008-08-07. PMID:18487850. |
infection and alzheimer's disease: the apoe epsilon4 connection and lipid metabolism. |
2008-08-07 |
2023-08-12 |
Not clear |
| Nicolas Cherbuin, Kaarin J Anstey, Perminder S Sachdev, Jerome J Maller, Chantal Meslin, Holly A Mack, Wei Wen, Simon Eastea. Total and regional gray matter volume is not related to APOE*E4 status in a community sample of middle-aged individuals. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 63. issue 5. 2008-07-15. PMID:18511754. |
the apoe*e4 allele has been associated with greater gray matter atrophy and with alzheimer's disease. |
2008-07-15 |
2023-08-12 |
Not clear |
| Piotr Lewczuk, Johannes Kornhuber, Hugo Vanderstichele, Eugeen Vanmechelen, Hermann Esselmann, Mirko Bibl, Stefanie Wolf, Markus Otto, Udo Reulbach, Heike Kölsch, Frank Jessen, Johannes Schröder, Peter Schönknecht, Harald Hampel, Oliver Peters, Erik Weimer, Robert Perneczky, Holger Jahn, Christian Luckhaus, Ulrich Lamla, Tillmann Supprian, Juan Manuel Maler, Jens Wiltfan. Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17239996. |
concentration of biomarkers of alzheimer's disease in cerebrospinal fluid (csf) was measured with multiplexing technology (n=223), and compared to the results of elisa assays in patients with early dementias or mild cognitive impairment (mci) collected at 12 gerontopsychiatric university departments, and apoe genotyping was performed. |
2008-06-20 |
2023-08-12 |
human |