| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert P Erickson, Katherine Larson-Thomé, Lyndon Weberg, Aleksandra Szybinska, Malgorzata Mossakowska, Maria Styczynska, Maria Barcikowska, Jacek Kuznick. Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population. Neuroscience letters. vol 447. issue 2-3. 2009-04-09. PMID:18834923. |
there is abundant evidence that cholesterol metabolism, especially as mediated by the intercellular transporter apoe, is involved in the pathogenesis of sporadic, late-onset alzheimer disease (slad). |
2009-04-09 |
2023-08-12 |
caenorhabditis_elegans |
| Gerdien Kramer, Wiesje M van der Flier, Conny de Langen, Marinus A Blankenstein, Philip Scheltens, Cornelis J Sta. EEG functional connectivity and ApoE genotype in Alzheimer's disease and controls. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 119. issue 12. 2009-04-08. PMID:18848805. |
eeg functional connectivity and apoe genotype in alzheimer's disease and controls. |
2009-04-08 |
2023-08-12 |
Not clear |
| Gerdien Kramer, Wiesje M van der Flier, Conny de Langen, Marinus A Blankenstein, Philip Scheltens, Cornelis J Sta. EEG functional connectivity and ApoE genotype in Alzheimer's disease and controls. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 119. issue 12. 2009-04-08. PMID:18848805. |
we examined the relation between apolipoprotein e epsilon4 allele (apoe epsilon4) genotype and functional connectivity measured by electroencephalography (eeg) in patients with alzheimer's disease (ad) and patients with subjective complaints (sc). |
2009-04-08 |
2023-08-12 |
Not clear |
| Nunzio Pomara, Kenneth D Belzer, Raul Silva, Thomas B Cooper, John J Sidti. The apolipoprotein E epsilon4 allele and memory performance in HIV-1 seropositive subjects: differences at baseline but not after acute oral lorazepam challenge. Psychopharmacology. vol 201. issue 1. 2009-04-07. PMID:18668226. |
the apoe epsilon4 allele, an established genetic risk factor for late-onset alzheimer's disease, has been linked to an increased risk for dementia especially in older individuals with hiv-1 infection. |
2009-04-07 |
2023-08-12 |
human |
| Ignat Ignatov, Christine Belden, Sandra Jacobson, Donald Connor, Marwan N Sabbag. Possible Alzheimer's disease in an apolipoprotein E2 homozygote. Journal of Alzheimer's disease : JAD. vol 16. issue 1. 2009-03-27. PMID:19158419. |
the objective of this study was to describe a case of alzheimer's disease in an apoe epsilon2/epsilon2 homozygote. |
2009-03-27 |
2023-08-12 |
Not clear |
| Ignat Ignatov, Christine Belden, Sandra Jacobson, Donald Connor, Marwan N Sabbag. Possible Alzheimer's disease in an apolipoprotein E2 homozygote. Journal of Alzheimer's disease : JAD. vol 16. issue 1. 2009-03-27. PMID:19158419. |
here we report an 87-year-old apoe epsilon2/epsilon2 female who meets clinical criteria for alzheimer's disease, with confirmation from neuropsychological testing and pet scan. |
2009-03-27 |
2023-08-12 |
Not clear |
| Daniel J Berlau, María M Corrada, Elizabeth Head, Claudia H Kawa. APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest old. Neurology. vol 72. issue 9. 2009-03-25. PMID:19255410. |
apoe epsilon2 is associated with intact cognition but increased alzheimer pathology in the oldest old. |
2009-03-25 |
2023-08-12 |
Not clear |
| Daniel J Berlau, María M Corrada, Elizabeth Head, Claudia H Kawa. APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest old. Neurology. vol 72. issue 9. 2009-03-25. PMID:19255410. |
many studies have examined the role of apoe genotype in the development of dementia, specifically alzheimer disease (ad). |
2009-03-25 |
2023-08-12 |
Not clear |
| Maria Styczyńska, Joanna B Strosznajder, Dorota Religa, Małgorzata Chodakowska-Zebrowska, Anna Pfeffer, Tomasz Gabryelewicz, Grzegorz A Czapski, Małgorzata Kobryś, Gytis Karciauskas, Maria Barcikowsk. Association between genetic and environmental factors and the risk of Alzheimer's disease. Folia neuropathologica. vol 46. issue 4. 2009-03-17. PMID:19169966. |
the only well confirmed genetic risk factor for sporadic alzheimer's disease (ad) is the possession of apolipoprotein e (apoe) epsilon4 allele. |
2009-03-17 |
2023-08-12 |
Not clear |
| A R Morgan, P Hollingworth, R Abraham, S Lovestone, C Brayne, D C Rubinsztein, A Lynch, B Lawlor, M Gill, M C O'Donovan, M J Owen, J William. Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 1. 2009-03-10. PMID:18452187. |
a recent scan of single nucleotide polymorphisms (snps) in the region 40-107 mb on chromosome 10q in a large japanese case-control cohort identified six snps in or near the dynamin-binding protein gene (dnmbp) that were associated with late onset alzheimer's disease (load) in individuals lacking the apoe epsilon4 allele [kuwano et al. |
2009-03-10 |
2023-08-12 |
human |
| Allen D Rose. The medical and economic roles of pipeline pharmacogenetics: Alzheimer's disease as a model of efficacy and HLA-B(*)5701 as a model of safety. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 1. 2009-03-09. PMID:18923406. |
two important examples are discussed, the association of apoe genotypes to the demonstration of actionable efficacy signals for the use of rosiglitazone for alzheimer's disease; and the identification of hla-b(*)5701 as a highly sensitive and specific predictive marker for abacavir treated patients who will develop hypersensitivity syndrome (hss). |
2009-03-09 |
2023-08-12 |
Not clear |
| Guo-mei Tang, Ming-yuan Zhang, San-duo Jiang, Yi-ping Qian, Dong-xiang Wan. [A study on the relation between the apolipoprotein E promoter -427C/T polymorphism and Alzheimer's disease]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 20. issue 3. 2009-02-25. PMID:12778455. |
to determine the relation between the apolipoprotein e(apoe) promoter -427c/t polymorphism and alzheimer's disease (ad) in a chinese han population in shanghai. |
2009-02-25 |
2023-08-12 |
Not clear |
| Nicole Helbecque, Dominique Cottel, Philippe Amouye. Low-density lipoprotein receptor-related protein 8 gene polymorphisms and dementia. Neurobiology of aging. vol 30. issue 2. 2009-02-19. PMID:17614163. |
the sole known genetic risk factor for sporadic alzheimer's disease (ad) is the gene encoding apolipoprotein e (apoe), but the underlying mechanism is still under debate. |
2009-02-19 |
2023-08-12 |
human |
| B Z Alizadeh, O T Njajou, M R Millán, A Hofman, M M Breteler, C M van Duij. HFE variants, APOE and Alzheimer's disease: findings from the population-based Rotterdam study. Neurobiology of aging. vol 30. issue 2. 2009-02-19. PMID:17628213. |
hfe variants, apoe and alzheimer's disease: findings from the population-based rotterdam study. |
2009-02-19 |
2023-08-12 |
Not clear |
| Nicola Filippini, Anil Rao, Sally Wetten, Rachel A Gibson, Michael Borrie, Danilo Guzman, Andrew Kertesz, Inge Loy-English, Julie Williams, Thomas Nichols, Brandon Whitcher, Paul M Matthew. Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. NeuroImage. vol 44. issue 3. 2009-02-19. PMID:19013250. |
anatomically-distinct genetic associations of apoe epsilon4 allele load with regional cortical atrophy in alzheimer's disease. |
2009-02-19 |
2023-08-12 |
Not clear |
| Nicola Filippini, Anil Rao, Sally Wetten, Rachel A Gibson, Michael Borrie, Danilo Guzman, Andrew Kertesz, Inge Loy-English, Julie Williams, Thomas Nichols, Brandon Whitcher, Paul M Matthew. Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. NeuroImage. vol 44. issue 3. 2009-02-19. PMID:19013250. |
apoe epsilon4 is the best-established genetic risk factor for sporadic alzheimer's disease (ad). |
2009-02-19 |
2023-08-12 |
Not clear |
| Nicola Filippini, Anil Rao, Sally Wetten, Rachel A Gibson, Michael Borrie, Danilo Guzman, Andrew Kertesz, Inge Loy-English, Julie Williams, Thomas Nichols, Brandon Whitcher, Paul M Matthew. Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. NeuroImage. vol 44. issue 3. 2009-02-19. PMID:19013250. |
our aim was to define the relationship between apoe epsilon4 allele load and regionally-specific brain cortical atrophy in alzheimer's disease (ad). |
2009-02-19 |
2023-08-12 |
Not clear |
| Masood Bazrgar, Mehran Karimi, Mohsen Fathzadeh, Sara Senemar, Farah Peiravian, Ashraf Shojaee, Mostafa Saada. Apolipoprotein E polymorphism in Southern Iran: E4 allele in the lowest reported amounts. Molecular biology reports. vol 35. issue 4. 2009-02-09. PMID:17594534. |
common apoe alleles are in association with an increase in risk for central nervous and cardiovascular diseases such as alzheimer's disease, dementia, multiple sclerosis, atherosclerosis, coronary heart disease, hyperlipoproteinemia and stroke. |
2009-02-09 |
2023-08-12 |
Not clear |
| Philipp A Thomann, Ann-Sophie Roth, Vasco Dos Santos, Pablo Toro, Marco Essig, Johannes Schröde. Apolipoprotein E polymorphism and brain morphology in mild cognitive impairment. Dementia and geriatric cognitive disorders. vol 26. issue 4. 2009-02-09. PMID:18843182. |
the apolipoprotein e (apoe) genotype has been confirmed as the major genetic risk factor for late-onset alzheimer's disease (ad). |
2009-02-09 |
2023-08-12 |
Not clear |
| Gregory A Jicha, Joseph E Parisi, Dennis W Dickson, Ruth H Cha, Kris A Johnson, Glenn E Smith, Bradley F Boeve, Ronald C Petersen, David S Knopma. Age and apoE associations with complex pathologic features in Alzheimer's disease. Journal of the neurological sciences. vol 273. issue 1-2. 2009-02-06. PMID:18653200. |
age and apoe associations with complex pathologic features in alzheimer's disease. |
2009-02-06 |
2023-08-12 |
Not clear |