| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gregory A Jicha, Joseph E Parisi, Dennis W Dickson, Ruth H Cha, Kris A Johnson, Glenn E Smith, Bradley F Boeve, Ronald C Petersen, David S Knopma. Age and apoE associations with complex pathologic features in Alzheimer's disease. Journal of the neurological sciences. vol 273. issue 1-2. 2009-02-06. PMID:18653200. |
the risk for alzheimer's disease (ad) is influenced by both age and apoe status. |
2009-02-06 |
2023-08-12 |
Not clear |
| Tania Marcourakis, Valéria S Bahia, Elisa M Kawamoto, Carolina D Munhoz, Renata Gorjão, Rinaldo Artes, Fernando Kok, Paulo Caramelli, Ricardo Nitrini, Rui Curi, Cristoforo Scavon. Apolipoprotein E genotype is related to nitric oxide production in platelets. Cell biochemistry and function. vol 26. issue 8. 2009-01-23. PMID:18846579. |
the presence of the epsilon4 allele of apolipoprotein e (apoe) is considered a risk factor for sporadic alzheimer's disease (ad). |
2009-01-23 |
2023-08-12 |
Not clear |
| Ghania Ait-ghezala, Laila Abdullah, Claude-Henry Volmar, Daniel Paris, Cheryl A Luis, Amita Quadros, Benoit Mouzon, Myles A Mullan, Andrew P Keegan, Julia Parrish, Fiona C Crawford, Venkatarajan S Mathura, Michael J Mulla. Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease. Cytokine. vol 44. issue 2. 2009-01-14. PMID:18835787. |
diagnostic utility of apoe, soluble cd40, cd40l, and abeta1-40 levels in plasma in alzheimer's disease. |
2009-01-14 |
2023-08-12 |
Not clear |
| Lars Bertram, Christoph Lange, Kristina Mullin, Michele Parkinson, Monica Hsiao, Meghan F Hogan, Brit M M Schjeide, Basavaraj Hooli, Jason Divito, Iuliana Ionita, Hongyu Jiang, Nan Laird, Thomas Moscarillo, Kari L Ohlsen, Kathryn Elliott, Xin Wang, Diane Hu-Lince, Marie Ryder, Amy Murphy, Steven L Wagner, Deborah Blacker, K David Becker, Rudolph E Tanz. Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. American journal of human genetics. vol 83. issue 5. 2009-01-06. PMID:18976728. |
genome-wide association analysis reveals putative alzheimer's disease susceptibility loci in addition to apoe. |
2009-01-06 |
2023-08-12 |
Not clear |
| Suzanne Zeitouni, Brian S Ford, Sean M Harris, Mandolin J Whitney, Carl A Gregory, Darwin J Procko. Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs). BMC biotechnology. vol 8. 2008-12-31. PMID:18823563. |
homozygosity for apoe epsilon4 is associated with atherosclerosis and alzheimer's disease whereas apoe epsilon2 and epsilon3 tend to be protective. |
2008-12-31 |
2023-08-12 |
mouse |
| Hsuan Pu Chen, Andy Lin, Joshua S Bloom, Arshad H Khan, Christopher C Park, Desmond J Smit. Screening reveals conserved and nonconserved transcriptional regulatory elements including an E3/E4 allele-dependent APOE coding region enhancer. Genomics. vol 92. issue 5. 2008-12-18. PMID:18718521. |
within the coding sequence of the apoe gene we identified an enhancer for the e4 allele associated with alzheimer's disease, but not e3. |
2008-12-18 |
2023-08-12 |
human |
| Lisa Delano-Wood, Wes S Houston, Jennifer A Emond, Natalie L Marchant, David P Salmon, Dilip V Jeste, Leon J Thal, Mark W Bond. APOE genotype predicts depression in women with Alzheimer's disease: a retrospective study. International journal of geriatric psychiatry. vol 23. issue 6. 2008-12-17. PMID:18058831. |
apoe genotype predicts depression in women with alzheimer's disease: a retrospective study. |
2008-12-17 |
2023-08-12 |
Not clear |
| I H G B Ramakers, P J Visser, P Aalten, O Bekers, K Sleegers, C L van Broeckhoven, J Jolles, F R J Verhe. The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology. Dementia and geriatric cognitive disorders. vol 26. issue 2. 2008-12-16. PMID:18617739. |
the association between apoe genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and alzheimer pathology. |
2008-12-16 |
2023-08-12 |
human |
| I H G B Ramakers, P J Visser, P Aalten, O Bekers, K Sleegers, C L van Broeckhoven, J Jolles, F R J Verhe. The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology. Dementia and geriatric cognitive disorders. vol 26. issue 2. 2008-12-16. PMID:18617739. |
we investigated whether the effect of the apoe genotype on memory in subjects with mci was dependent on age and underlying alzheimer disease (ad) pathology. |
2008-12-16 |
2023-08-12 |
human |
| Michael R Cassidy, J Scott Roberts, Thomas D Bird, Ellen J Steinbart, L Adrienne Cupples, Clara A Chen, Erin Linnenbringer, Robert C Gree. Comparing test-specific distress of susceptibility versus deterministic genetic testing for Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 4. issue 6. 2008-12-10. PMID:19012865. |
genetic risk for alzheimer's disease (ad) can be conferred by the susceptibility polymorphism apolipoprotein e (apoe), where the epsilon 4 allele increases the risk of developing late-onset ad but is not a definitive predictor of the disease, or by autosomal dominant mutations (eg, the presenilins), which almost inevitably result in early-onset familial ad. |
2008-12-10 |
2023-08-12 |
Not clear |
| Elin S Blom, Peter Holmans, Sampath Arepalli, Omanma Adighibe, Marian L Hamshere, Margaret Gatz, Nancy L Pedersen, A L Mina Bergem, Michael J Owen, Paul Hollingworth, Alison Goate, Julie Williams, Lars Lannfelt, John Hardy, Fabienne Wavrant-De Vrièze, Anna Glase. Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18161859. |
does apoe explain the linkage of alzheimer's disease to chromosome 19q13? |
2008-12-04 |
2023-08-12 |
Not clear |
| Elin S Blom, Peter Holmans, Sampath Arepalli, Omanma Adighibe, Marian L Hamshere, Margaret Gatz, Nancy L Pedersen, A L Mina Bergem, Michael J Owen, Paul Hollingworth, Alison Goate, Julie Williams, Lars Lannfelt, John Hardy, Fabienne Wavrant-De Vrièze, Anna Glase. Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18161859. |
we have studied the impact of the apolipoprotein e gene (apoe) on the chromosome 19 linkage peak from an analysis of sib-pairs affected by alzheimer's disease. |
2008-12-04 |
2023-08-12 |
Not clear |
| Maura Poli, Luisa Benerini Gatta, Carlo Lovati, Claudio Mariani, Daniela Galimberti, Elio Scarpini, Ida Biunno, Massimo Musicco, Roberto Dominici, Alberto Albertini, Dario Finazz. Interaction between the APOE epsilon4 allele and the APH-1b c + 651T > G SNP in Alzheimer's disease. Neurobiology of aging. vol 29. issue 10. 2008-11-17. PMID:17466415. |
interaction between the apoe epsilon4 allele and the aph-1b c + 651t > g snp in alzheimer's disease. |
2008-11-17 |
2023-08-12 |
Not clear |
| Hyang-Sook Hoe, George William Rebec. Functional interactions of APP with the apoE receptor family. Journal of neurochemistry. vol 106. issue 6. 2008-11-07. PMID:18554321. |
interestingly, many of these app-interacting proteins also interact with the family of receptors for apolipoprotein e (apoe), the alzheimer's disease risk factor. |
2008-11-07 |
2023-08-12 |
Not clear |
| Alexandra Bour, Jeannette Grootendorst, Elise Vogel, Christian Kelche, Jean-Cosme Dodart, Kelly Bales, Pierre-Henri Moreau, Patrick M Sullivan, Chantal Mathi. Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks. Behavioural brain research. vol 193. issue 2. 2008-11-03. PMID:18572260. |
apolipoprotein (apo) e4, one of three human apoe (h-apoe) isoforms, has been identified as a major genetic risk factor for alzheimer's disease and for cognitive deficits associated with aging. |
2008-11-03 |
2023-08-12 |
mouse |
| Carlijn R Hooijmans, Amanda J Kiliaa. Fatty acids, lipid metabolism and Alzheimer pathology. European journal of pharmacology. vol 585. issue 1. 2008-10-31. PMID:18378224. |
cardiovascular risk factors such as high serum cholesterol, presence of the apolipoprotein epsilon4 (apoe epsilon4) allele and hypertension, play important roles in the development of alzheimer's disease. |
2008-10-31 |
2023-08-12 |
Not clear |
| Carlijn R Hooijmans, Amanda J Kiliaa. Fatty acids, lipid metabolism and Alzheimer pathology. European journal of pharmacology. vol 585. issue 1. 2008-10-31. PMID:18378224. |
because of the great importance of lipid diets and metabolism in preventative treatment against both alzheimer's disease and cardiovascular disease, long-chain polyunsaturated fatty acids from fish oil, apoe genotype and cholesterol metabolism in correlation with alzheimer's disease will be reviewed. |
2008-10-31 |
2023-08-12 |
Not clear |
| Lars Bertram, Rudolph E Tanz. Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nature reviews. Neuroscience. vol 9. issue 10. 2008-10-16. PMID:18802446. |
the genetic underpinnings of alzheimer's disease (ad) remain largely elusive despite early successes in identifying three genes that cause early-onset familial ad (those that encode amyloid precursor protein (app) and the presenilins (psen1 and psen2)), and one genetic risk factor for late-onset ad (the gene that encodes apolipoprotein e (apoe)). |
2008-10-16 |
2023-08-12 |
Not clear |
| Ines Jilani, Natalia Grabar, Pierre Meneton, Marie-Christine Jaulen. Assessment of biomedical knowledge according to confidence criteria. Studies in health technology and informatics. vol 136. 2008-09-30. PMID:18487731. |
we propose in this study, an implementation of these confidence markers for functional annotation of the human gene apolipoprotein (apoe) thought to be involved in alzheimer's disease. |
2008-09-30 |
2023-08-12 |
human |
| Sabrina Utter, Irfan Y Tamboli, Jochen Walter, Ajeet Rijal Upadhaya, Gerd Birkenmeier, Claus U Pietrzik, Estifanos Ghebremedhin, Dietmar Rudolf Tha. Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes. Journal of neuropathology and experimental neurology. vol 67. issue 9. 2008-09-30. PMID:18716559. |
apolipoprotein e (apoe) plays a role in the pathogenesis of alzheimer disease (ad). |
2008-09-30 |
2023-08-12 |
human |